[4:25] The odds of reversing type II diabetes.

[6:05] Can we age better with stable blood sugar?

• Glucose signaling leads to cellular senescence.

[8:12] Should we measure insulin alongside blood sugar?

• Most people want a fasted insulin of <10.
• A1C levels will be the last measure to go high.
• 6-5.7 A1C is associated with negative outcomes.

[11:33] Is A1C an outdated measure?

• It assumes that the RBC has a specific lifespan.
• A transfusion or anemia, for example, will skew the results.

[13:18] Is type II diabetes the #1 killer in America?

• 100 million Americans don’t know that they are pre-diabetic.

[15:40] high blood pressure from insulin production- type II diabetes is an acquired disease.

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[27:20] The cost of functional healthcare.

[29:40] Most of the info for reversing Type II diabetes is on the internet right now.

• The order of operations in which one approaches it matters.
• A good physician can act as one’s Sherpa.

[35:47] Dietary recommendations for diabetes.

• Should we really be recommending carbs to diabetics?
• Most diabetics cannot handle them.
• Staying on protein only will also result in insulin resistance in the long term.
• You also have to give options that people will be compliant with.

[38:10] Gluconeogenesis.

• Excess protein does spike blood sugar.

[40:55] Top mistakes of diabetics.

• Not practicing moderation.
• Not knowing personal tolerance to carbs.
• Sedentary lifestyle.

[44:36] The problems form modern technology.

• Poor sleep leads to impaired insulin sensitivity.
• Gut disbiosis.

[53:50] PDE5 inhibitors increase insulin production in the absence of carbs.

[55:30] Downsides of metformin.

[1:03:30] Purpose of the study on male test during puberty and correlations with brain health.

[1:04:48] Do neurosis usually start during puberty?

[1:06:55] Is there any research on androgen blockade and schizophrenia?

[1:08:30] Study design.

• Birth cohort
• 10,000 kids.
• Measured serum test levels and compared to how their brains responded to different facial expressions ( social cognition).
• Pubertal test levels mattered in relation to current test levels.
• Low pubertal levels led to greater effect from current low levels.

[1:12:25] Could the mother’s levels influence sexual preference or neurological state of the children?

• A male twin will have a more feminine face if in the womb with a female twin.

[1:17:00] The environment’s role in this phenomenon.

[1:23:35] Possible fallacy of using eye measurements as a proxy