Dr. Elizabeth Yurth, MD

We now know that the development of osteoarthritis is more than just a response to mechanical loading. That's actually a good thing because it opens up better ways to treat it.

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SHR # 2397 :: The Pep Talk: Treating Osteoarthritis - Beyond Stem Cells & PRP

Show Notes:

[1:20] Osteoarthritis affects ~80% of aging individuals.

[5:00] Most joint replacement surgeries do not have long-term success.

[7:16] The culprit of osteoarthritis.

• Levels of overall inflammation in the body.
• Genetic components.
• Autoimmune OA is a possibility as well; this will wear our all of the joints in the body more quickly.

[11:00] Hylauronic acid injections.

• They are not a long-term solution, but they do help.

[16:20] Platelet and stem-cell therapy are better options but do not fix the environment that caused the problem.

• Dietary and stressor interventions must be made.

[18:20] Pro inflammatory diets.

• Nobody fares well on a high sugar diet.

[21:30] Treating distended gut problems.

• Betaine HCl between meals.
• Glutamine.
• BPC-157.
• Elimination of sugar.
• Stevia.

[28:39] Even something as simple as BPC-157 can help OA tremendously.

[29:35] AOD-9604.

• Originally for fat loss.
• Completely regenerated and maintained cartilage in rabbits.
• Usually stacked with hyaluronic acid.

[33:10] Will AOD-9604 for fat loss see crossover benefits.

• Yes, there is a systemic benefit.

[34:55] CJC and Ipamorelin

[35:17] Pentosan polysulfate.

• It is a synthetic cellulose molecule from the beechwood tree.
• Reverses arthritis long-term.
• Lowers C2C levels.
• Increases bloodflow to the joint and the bone.
• 2x/ week for 6 weeks.
• It is a minimal blood thinner.
• Can be done subcutaneous.

[42:03] Start using these agents before  stem-cell and PRP therapy.

[44:51] Oral pentosane polysulfate can be used orally, but there is a larger risk of blood thinning.

[45:39] Collagen peptides.

• Improved walking distance in a knee-replacement group.
• Take with a small amount of vitamin C pre workout.

[51:51] Don’t let the cost of therapy scare you.

• Most people have a 3-5 thousand dollar deductible.
• This offsets the cost of a treatment that actually works.

Show Transcript SHR # 2397 :: The Pep Talk: Treating Osteoarthritis - Beyond Stem Cells & PRP