[00:00:00] Welcome back to another episode of superhuman radio. As you know, today is every other Thursday and on every other Thursday. I'm joined by my good friend Adam Lamb who were going to play his theme music now. The first step to changing your life starts with the ReNew Life Show with Adam lamp

[00:00:55] your to get this and download it to your iPhone. And whenever you walk around the house like [00:01:00] you walk from the living room to the kitchen, you should play it. So you have your own you actually have your own theme. Music. How about I like it. I want a copy of it. I think it's kind of every time you play it.

[00:01:10] I'm like, oh, it's nice. I'll send it to you. I will I will you know you. Dr. Jeff golini did with all the gears that we did science for humans. He put them all on his on hold button. So if you call All American pharmaceutical get put on hold you listen, it's weird when I used to call them and I would hear my voice on their on their whole button.

[00:01:31] It was like in the middle of a yeah. Yeah, it's pretty cool. You can do that with these shows that you and I do you could have somebody excerpt them and put them into your hole button. I never have anyone on whole it's not good but not just that's a good that's a good. Actually, that's what people animal.

[00:01:46] So this is going to be a good discussion. Actually. We planned on talking about this and then Wyatt Everhart a listener who was also a high-level media person. He does the news. I want to say in either [00:02:00] in the Carolinas or in Maryland. I think Marilyn. And he sent the some questions that feed right into this nicely.

[00:02:06] So we're going to talk about lab tests because this this is this is an area of a lot of Confusion And the reason there's a lot of confusion is because doctors kind of willy-nilly decide what they. To run on the labs and it's there's no apparently no uniform consensus among doctors. Would you agree with that?

[00:02:28] Yeah, I think that it's like any situation if depending on what you're looking for. There are certain tools. You bring to the Dig right if you're mining gold or silver. I don't know anything about either one of those but I assume that different things require your dinosaur bones right like you're going to.

[00:02:43] You're going to have different tools for that dig, right? And if you're not experienced in, you know, digging up dinosaur bones and your are experiencing gold-mining. You may not be frightened. You mean you're equipped to Dugout to dig for one, but maybe not [00:03:00] necessarily the other one. I agree completely a good analogy actually.

[00:03:02] Yeah. Yeah digging digging digging is the one thing they have in common is digging and that's what doctors getting in trouble. So they think that oh, I know, you know what I need to run but science in this space has changed over the past five years so dramatically.  You know one thing that I always explain to us in the clients were talking to him about onboarding to is like listen, we don't have we've talked about we don't know everything.

[00:03:30] We're not a hundred percent, right? There's some trial and error. For we are follow-up process is so important why we touch base every week to see how people are feeling but it also goes back to our blood work compared to like what we used to look at before. So what we looked at, you know a year or two ago to what we look at today, right?

[00:03:46] And it's we keep you know as explained to you earlier about we'll talk about me a little later about some an AI. Thing that we're working on that's going to like I think revolutionized the hormones play industry for 4 people but [00:04:00] constantly refining the data right any anytime that you just like tears it this we don't need anything else, right?

[00:04:06] That's crazy talk because you if you're if you're constantly learning you do have to be constantly changing or adjusting a little bit and the other side of that discussion is so it's evil. No one should be using it and so. And this is this is the problem with science in general and I posted something on Facebook.

[00:04:25] Just recently I said if you how to spot a fraud Health Guru and then it was like insert here and then is the cause for all diseases. It's like when people started making these broad stroke generalizations like a eyes are evil. No one should be taking them right an injustice. That is just as dumb as everybody should be taking a eyes.

[00:04:50] Right? Right any absolutes in medicine is different that's you know, we're clients again like in the onboarding process and they have questions and they're like, what am I going to do [00:05:00] this or what about this or what's the dosage of what I'm like man, we don't know your blood work soon. Come back.

[00:05:05] Our doctors going to take a look at it and they're gonna make recommendations specifically and your blood work not for any other reason because we don't know, you know what I mean? Like for example, you know looking at some Labs at the new folks that came through I was looking at like we had two guys who've never done any hormone replacement therapy in their life there and they warm was like late 40s early 50s that both have low in the low range of estradiol it below.

[00:05:31] I'd have to pull it up to find the exact Mark but below 10. Tendo. Yeah, and that's is that picograms per deck Alito is that not a problem the scale the picograms? Yeah, so I thought I'd that's the thing because testosterone is an anagram. So and then this is a really important discussion when we talk about estradiol specifically.

[00:05:54] I want to get something out of the way up front. This was one of Wyatt Everhart questions two [00:06:00] men should be getting high. It's tivity estradiol test, which is very different than a woman's test. And the reason for that is the high sensitivity is sensitive from 0 to 20. Okay. This is where know it's 0 to 40.

[00:06:21] This is where men get in trouble because when they use the estradiol test made for women. There's is not sensitive down on that low end because women are always up here. Why are we going to even think about you know anybody down there? And so if guys don't specify specifically say to their doctor are you getting me the high sensitivity estradiol test?

[00:06:44] They're not going to get it. They're going to get one that's going to have a huge margin of error in the zone that men always fall into that's that's it. That's it thing that you have to watch out for. Yeah, and we see, you know [00:07:00] in the the things, you know, for estradiol for example or total estrogens.

[00:07:04] There's those would be the two that we typically kind of scrub to see and you know based on our data. We have ranges of things like where it's at. You know, I'm looking at a guy right here is estradiol. Is it 5.3? That's broke that's lower touch. Anything is like right. Just ask her own is that 296?

[00:07:25] That's what that but. That's probably. He's all oh he's got no testosterone either. Well, yeah in this guy, you know for conversation has had some depression issues right in the the other things that you know, we don't not look at look at this. There's deeper Dives at the Docks do with this and potentially other medication that the other.

[00:07:44] This guy's on that could be leading to lower estradiol things like that. Like I don't know but it's stuff that we're looking at that right. We look into right we take like I said, we take that deep dive to make sure that everything is super [00:08:00] custom to that individual. So so let's talk about what the minimum is what people should be expecting.

[00:08:09] Big picture one thing I see like guys like you and I Carl were in the know we talk about the stuff every single day. And if we were to take a step back right think of the I try to think of like the daily person that doesn't know anything about blood work a lot of times. You know. One thing is we see that's overly focused on testosterone.

[00:08:28] Everyone's like I did this morning was like or do you want my testosterone be I'm like, I don't know our Doc's are going to see where you're at. And when you feel great if you're healthy, you know, I mean, that's where you should be. Depending on where you're so you know, maybe it's that thousand to twelve hundred range is like the shot.

[00:08:43] Like how do you feel there is a too much because we have clients that it's 650. I feel great and we have clients that they need to be near 1500. A lot of it has to do with the rest hpg. And I would say almost every single time that has to do with our shbg where that's at what that ratio looks like, but that's why we look at [00:09:00] that.

[00:09:00] But what I say one thing for the. Folks listen that are very educated in the blood work side of it is there's a lot of things that have to be looked at not just testosterone right and LH F. Sh, sh Bee Gees probably the number one thing that isn't in should be looked at, you know, if you're looking at this dosterone you need to look at shbg.

[00:09:18] This is going to tell the story of whether the testosterone is high or low how effective it's being in your body right with it, whether it's enough things therefore to be binded to and then General Health stuff, you know, like in one of our kind of mottos is it. Healthy you're in charge. If you're unhealthy were in charge right meaning that if you know if guys come over that their hemoglobin or hematocrit is jacked up because they've been not doing part.

[00:09:43] You know, we see all whatever you write 300 milligrams of testosterone. Every two weeks is their what their doctor has like, that's crazy. Right? And and so but then maybe their cholesterol it maybe too much of it in AI of certain kind that people are sensitive to be natural lipids that I shoplifted but remember [00:10:00] not every.

[00:10:01] Right we have in so there's different situations and we have to help sometimes get people better, you know to the the AI kind of discussion like there's some folks. We've had come over recently from a clinic that they're doing one milligram of AI every other day. No, no one needs that's a lot of time.

[00:10:18] It's because you're talking about you're talking about ancestors all your talk about. Yeah, that's what all was crushing that's going to crush your estrogen Crush, right? It's so but there we also we have. Don't do NT estrogen. We have folks that do a half half a milligram and as a result every other day limited, it might be to write but different people are differently in especially in the the one guy thinking of the does.

[00:10:44] He's been a patient for five years, right? We've been monitoring his additional Health measures are healthier today than he what you know, that's right find it at work. I know we're doing the right thing is Doc is cardio is cardiologist. Actually just coming December emerging is Don but he was saying that.

[00:11:00] [00:11:00] Like man, I don't know what the hell you're doing, but you're he's like, you're almost turning back the clock, you know, and so he got back to us. He's like man you guys are you know, we're changing his life as from a health standpoint. Even if you doing those additional testing, but the the going back to the bloodwork side is looking at things that also can be affected by testosterone adversely.

[00:11:21] Right? So if your senior to stop stirring to 1200 and you feel amazing, but hemoglobin hematocrit are high. We usually only see we never see it with our with our patients gas with you. But sometimes it happens with folks coming on board. Usually from injections. Usually from the once-a-week errs, and then or you know cholesterol blood pressure, right if your blood pressure is cranking up because of that just awesome.

[00:11:48] It's a risk to and so watching all of that stuff. And then finding out how you feel is what the most important thing is as opposed to, you know, people we see coming from other clinics [00:12:00] sometimes with low T clinics that they're just checking to stop strong. They never check and that and that and that should be that should be the red flag.

[00:12:06] Like if you walk into a clinic for hormone replacement therapy and they go, you know, we start everybody off with this protocol. Yeah you that that that's the day using the same cookie cutter Approach at the big farmer uses. Everybody just takes this. Everybody takes this pill for that which in and of itself is also flawed but it's and it's hard and but the problem is that people want that people want I had a guy message me this morning.

[00:12:35] I gave him your name. Thank you. He said there's a clinic that just opened up in my town and they do the pellet. What do you think about the pellet testosterone pellets for men so high so, what do I message him back? What do you think I messaging back? I'm. Your back and said well what kind of testosterone what kind of testosterone are you on now?

[00:12:56] He goes, I'm not on any testosterone I said, well, [00:13:00] I would recommend that you start off with cream or injections first and to see how you respond. I said because once they put that pellet in you you're on that ride for three. And if you don't if it's not good for you or too high, or too low, you don't feel better.

[00:13:17] You have to wait three months for an adjustment. Imagine a missile that had to only adjust once every 10 minutes. It's not going to hit its Target. You know what I mean? No. No, so did you think I did the right thing at the right thing that I mean pellet for somebody who's been on for years, but right out of the gate somebody it's you know, and it goes in bed into this conversation to whether we're talking about estrogen and AI or pellet there like there's there's.

[00:13:42] Certain things that we have experienced in that we have success with like you and I talked about like the testosterone cream doing the scrotal application as opposed to we no one does that we don't have anyone to we don't have the experience. Maybe it's better but we know that the folks that put it on their forearm or the back of the knee the blood work comes back.

[00:13:59] They're good. [00:14:00] We're not messing with anything downstairs. The last thing I wanted someone to put something on there and there's some kind of adverse issue and yeah, it doesn't work anymore. And now we did that right right don't want that problem. Right? So there could the pellets that is one of my best friend's has been on pellets for eight years and he loved her.

[00:14:20] Yeah, and I might come on board will take care of, you know, do whatever right is real good for. And loves the pellets. So but in any situation, I think the a you don't you know, if the pellets were like yeah, you know, you get a little bit of Spike. Look at you always said like they turn the lights on in a warehouse and you're like, ah, well, of course, it's good, but could it be better?

[00:14:42] Could it be healthier? Could it be safer? I think in our opinion the cream is the easiest way because you. You can adjust your dose weekly if you have to daily. Yeah, well we can do it daily. Right? And so that's the part that we really really like and then the injections we don't have a beef [00:15:00] with them, but the they have to say also that so so that injections and the the weekly injections and the pellet have the same problems but different at a different magnitude, you know, your body likes to pulse testosterone.

[00:15:17] And now you're turning into a once-a-week pulse. Yeah, and now we're going to turn into it. We're going to turn into a once every three months pulse. Yeah, we have the daily injections, you know where some people are like, oh, well just do just daily do the daily injections. But here's the deal.

[00:15:35] Most people don't want it. They don't want me to write right? Like that's something like I said, like bring it back like you and I are talk about this every day. We've been in the space for a long time like Joe Blow business guy. He's like, dude. Put a needle anywhere. I'm not going to in a plane with what your needles and my carrot like they're not doing it.

[00:15:51] Yeah, so stigma to stick. Yeah, there's a stigma and at the end of the day like you're letting your hurt yourself and cream on your forearms. But as is [00:16:00] where there could be an issue potentially with, you know, giving your injection wrong or doing something goofy. It's rare, right, but it can happen and we just see the results.

[00:16:11] That happened a lot of guys I think are still on the sidelines with looking into hormone therapy because they think they have to go to the doctor and get a shot every week or two weeks or they have to just get a shot in general and they don't want to do it. You know what I mean? And so then when guys hear that we have there's a cream option and it works really well.

[00:16:30] They're like, oh cool. I meant I didn't know you do that, you know, and then they get the results. Let's go ahead and run through the list of what the male blood. Look like just go right down the list. Yeah, so if the CBC with differential platelet metabolic panel lipid panel with cholesterol HDL ratio DHEA to testosterone serum TSH igf-1.

[00:16:55] FSH LH PSA estrogen we do sometimes estrogen [00:17:00] total depends on the usually estradiol, right? And then the sh BG and from the shbg, there's a formula that you could take total testosterone serum and shbg and calculate free testosterone. Typically, yeah, I mean at least there's a an idea of if the shbg is hi there.

[00:17:24] They're free test will be low and if they're free test is high. It's usually a sign that they're shbg is low. But why would you go where lower but we're learning now not to be afraid of shbg this whole idea of Unbound testosterone is the only valuable testosterone will learning now is not true.

[00:17:39] That's not true. And that's something we did for like a few years ago that you know, we figured out like that doesn't. Don't ruin. It doesn't because I just had a guy just had a friend from Sweden to message me this week and said my shbg was 80 and I said what's the assay there and the high-end was like a hundred and twenty or something [00:18:00] like that or hundred and and and I said, how do you feel he goes?

[00:18:03] I feel fantastic. I just don't change it. I said why do you want to lower your shbg goes? Well, doesn't it deactivate testosterone? I says no, it actually is a chaperone think of it as a chaperone. It's the shuttle and what we'll do to with folks that have a higher shbg. Obviously, they need no higher levels of testosterone.

[00:18:25] If they're DHEA is typically low to well then will you know putting a having DHEA because it's also sex or more moves through there. It's very valuable to the body as far as directing hormone traffic work needs to go for example, and adding that DHEA to the mix to now if your lowest HP G guy you don't want to get that each that you don't want to get the DHEA and they're typically and and actually HCG becomes more of a priority because we see the HCG crank it back up, but if you have high shbg.

[00:18:53] 53 years old and your LH and FSH levels are fine. Typically, we're not putting you on HCG at that [00:19:00] point, right? Because we maybe it's every six months you do six weeks or something like that. So there's all these different, you know, I can share with you all these different little tweaks and formulas that they're not for everybody there only for something it's not.

[00:19:13] Yeah, it's not for one blood Mark. Yeah, right. It's not even if you don't say I just listed multiple reasons. Why based on this this this and this you're going to be here right now and that's what our Doc's do in just because we've been doing it. We've had the data, you know, we work with thousands of people you see all the stuff.

[00:19:31] You see the tweaks, you know, where he how they work right? Well, we're technology companies much as we are, you know, if anything we're just more of a health facility. Company than anything the doctors going to send this is not you know, that's not rocket science, but I'm figuring out the science side of it for the patient and how they feel and what that looks like from lab results is really important that CBC is where you're going to get your hematocrit from right Jeffrey.

[00:19:58] You're going to come out of it what [00:20:00] blows my mind and I say this but if you have to donate blood every six weeks while you're on hormone therapy, you're not doing it right and you should not have to disinfect. Do people that we see that are sensitive and and I would say almost a hundred percent of the time they're on injections, but our our client base doesn't have to do well the only way and I agree with you.

[00:20:24] You should not have to get blood drawn. Oh donate blood because of your HRT, but you may want to donate blood to keep iron storage low in your body because there's evidence that you'll age much better. Yeah, I get it. Right, you shouldn't be going because your hematocrit is so high the doctor the guys that come from clinics are like, oh, yeah, so I just I do this this and this I donate blood every six weeks and I'm like that you're doing it wrong.

[00:20:51] You know what I mean? It's like if you have to throw up every time you eat you're eating the wrong Foods, you're eating food just doesn't it's not a [00:21:00] normal thing to do and. Sometimes people think it is. I make donating blood right you want to do that once or twice a year and healthy like you just said, it's all I do it.

[00:21:08] I think it's smart and you're an opportunity to give back that others that may need it. But if you should have to do it every six weeks because you're on hormone therapy, and so those kind of things that we see. When the hematocrit and we also see it in, you know folks that are doing that 200 milligram every two weeks or 300 milligram.

[00:21:26] Every two weeks type spike is it just jacks the hemoglobin hematocrit out as opposed to having a more mainstream flow of stuff. So I would I would like to add expand on this list real quick. I'm going to run through and then I'm going to I'm going to throw some things in that I think are important.

[00:21:45] Also, obviously CBC metabolic panel perfect lipid panel with cholesterol HDL ratio. Perfect DHEA to testosterone serum. Perfect TSH. I really feel strongly [00:22:00] that doesn't tell enough of a story to tell if the thyroid is functioning properly because the thyroid. Version of hormones for it to truly work properly.

[00:22:11] So I think that total and free T3 total and free T4 reverse T3, which can cause problems it can cause the symptoms of hypothyroidism. Even when there's adequate thyroid hormone and you can figure that out right away when you look at the reverse T3, and then the last one. Is TPO thyroid antibodies to make sure that you don't have autoimmunity coming on that's going to start to destroy your thyroid.

[00:22:36] I feel strongly about those. The one that I think is really great that you have on your list that most doctors don't pull for men as follicle stimulating hormone. That's one that they pulled for women. In fact when I met dr. Tutera in Arizona when he was still alive and he was telling me about his pellet.

[00:22:55] He he's the guy who brought soda Pele to the. 8 and [00:23:00] he said he used follicle-stimulating hormone and luteinizing hormone to triangulate to tell if a woman had the right levels of estrogen and progesterone because if the woman still producing high levels of follicle-stimulating hormone, or is it luteinizing hormone, I think it's luteinizing hormone.

[00:23:20] She doesn't have enough estrogen he would he would he would get estrogen high enough that it would shut down. Production of luteinizing hormone follicle-stimulating hormone. I can't remember which one it is, but I but you pull these on men most doctors don't bother with that. Why do you pull these on men?

[00:23:36] It's to help see the communication of the natural testosterone production like so when those levels are low typically this poor communication between the testes in the brain basically to create testosterone and we can also find that if the communication is good, you know, the levels are functional and they are good that they're still a miscommunication and we.

[00:23:57] See that there's sometimes when that is like [00:24:00] let's say your your FSH and LH or in the fuel for five range, which is a decent not too high that a lot of times DHEA is low and DJs and people have Rosa DHEA will is does a great job at getting your hormones to go and do or they're supposed to kind of get where they need to go.

[00:24:18] It's almost like I use the analogy is it's like a traffic director and. But it gets kind of put on the curb because it doesn't like make you big and strong and like grrrr. It's a lot of times pi nobody pays attention to it. It's not sexy. Yeah, it's not out exactly how I want to get this up here myke bear says and he's right.

[00:24:39] The blood of bloodletting goes all the way back to Egyptian era at least bloodletting goes back to the beginning of recorded history when people started to document the sort of stuff and they were different but they were different reasons for it. Nobody was doing it because the HRT and the hemoglobin that we usually doing bloodletting because someone had some ominous illness and they would put [00:25:00] leeches on them and they would and they and and so.

[00:25:03] Um, I think bloodletting has always been around. You're right Mike but now it is actually we know it's a valuable tool in her and helping some people but it's along the shouldn't yeah. Yes for sure, but it shouldn't shouldn't be required in order for you to be on testosterone. Yeah. Yeah, you should you should be able to go your entire life and not have to do it but port for testosterone purposes not nothing like anything just.

[00:25:29] To clear out, you know, like just getting some of the old out write it I use it for better energy. Well, if I don't donate blood I'm kind of like sweet. I don't know the first thing I noticed the day I donate blood as I sleep really soundly that night and if it happens every time so I know it's not an accident.

[00:25:45] No, it's yeah, there's good things to do and like I said donate blood once or twice a year, you might save a life you could say, you know could help your own right, but if you have to do it on. Schedule. Yeah, because you're on [00:26:00] hormone therapy. You're doing hormones. Your hormone therapies is wrong.

[00:26:03] It's something's wrong with it. No doubt, you know, so one thing you mentioned the TSH the T3 T4 into T3 sensitive. You're correct. And here's what when folks ask me that question is the TSH is where it's going to give us a snapshot of the thyroid stimulating hormone. In the conversations we have are going to tell us where there might be some thyroid related issues.

[00:26:26] Yeah it but there's there's probably not even one in a hundred that have a T3 T4 conversion issue, right? So. Is that should everybody spend an extra hundred dollars? I don't know we die simply saying so basically you basically you bore sighting with TSH you're going oh, you know, the guy if the guy or gal is complaining about things that are considered in the domain of thyroid dysfunction and you look at the TSH and you go man.

[00:26:55] It's really high or it's really low. Well, then you will do follow me go. Yes a hundred [00:27:00] percent. But if they're not complaining about low energy being cold all the time and they're TSH is in the middle and you're like, okay, they're fine. I mean we could look at it just like we could look at everybody with low testosterone or too high to low sh T sh or unusually higher igf-1 and say you might have a pituitary tumor you need to go out and get an MRI done.

[00:27:21] If you know, but would be excessive right? I'll tell me that we still see you know, so when a woman recently her. Her igf-1 was let's say 286 or something for like a 47 year old woman is pretty excessive who's not taking anything to stimulate that who also had a TSH of like 5.6. That's pretty high.

[00:27:39] Yeah. Yeah, and so I said, Hey, listen, I'm not trying to scare you, but it wouldn't hurt to. Get in touch with your endo and have that conversation that to take a look and see maybe there's something there. Maybe there isn't we've helped people discover pituitary tumors and gratefully. We've never had anyone that was cancerous and it could be [00:28:00] something that's been there for their whole life right or something that came from something else.

[00:28:04] So to your point like when the Deep Dives needed we'll do it. I mean, we'll throw the kitchen sink at you at 12 weeks if you're a mess, but you know, that's when we use that that first. The blood work is just kind of like the general stuff that we know helps Turn All the Lights On that's needed unless we need to like get the spotlight out in the corner, right and which will do it that 12-week Mark.

[00:28:27] We're going to take a quick commercial break when we come back. I want to talk a little bit more about estrogen. Aromatase Inhibitors and maybe even some alternatives to Pharmaceuticals for aromatase Inhibitors and we're talking with Adam Lamb. The website is ReNew. Life are x.com. Check it out.

[00:28:43] We'll be right back.

[00:28:47] Welcome back. This is the ReNew Life RX show. I'm just going to pop this up here. Mike Baird during the break said look at Jordan Rubin Story the man lost so much weight had every blood test under the sun. No [00:29:00] doctors could figure it out. He wrote the makers died. He was actually a sponsor on superhuman radio for a while a few years ago when he introduced a bunch of new products and started promoting.

[00:29:12] The makers diet. Nice guy really nice guy. So the war rages on about aromatase Inhibitors and you and I have pretty much agreed.  It's stupid to hate aromatase Inhibitors and it's stupid to prescribe them to every patient that only blood work as you talked about. Can dictate and if you need an AI maybe you just need to lower the testosterone but there are anomalies there are people out there who are high aromatize has there really are so let's talk about some of the things that could be used as an alternative to an aromatase inhibitor dive into some of the things you mentioned that well again dim is one thing that we hear dim dim definitely calcium do glucose or a [00:30:00] vitamin.

[00:30:01] A zinc, but the truth is those are all good.  and.  Excuse me, how to clear my throat. Those are all good. And those may get you if your marginally high those may get you down where you belong but if you're on a regular dose of testosterone 250 milligrams a week or cream equating to probably 11 milligrams a day and.

[00:30:30] Who are high aromatize ER and you don't have a lot of body fat?  You need to look at your chronic inflammation inflammatory markers because here's why so when you look at the cytochrome p450 enzyme Cascade, which is the major enzyme Cascade in your liver. It affects every every process in your body has an effect on an effect the p450 cytochrome [00:31:00] Cascade.

[00:31:00] And those Cascades as they say that one feeds the other feeds the other feeds the other feeds the other it's like a train. Well, the precursor to aromatase is one that we've heard a lot in the past decade and that's cyclooxygenase Wilcox. You hear about cox-1 Inhibitors cox-2 Inhibitors to reduce pain and inflammation in the body.

[00:31:27] Well when cyclooxygenase is overexpressed because your body is an inflammatory Firehouse. Okay, then guess what goes through the roof aromatisse enzyme because the more of this you have the more of the downstream you have so if you're one of these people that your doctor goes, you know, We've got you on the lowest possible test dose your aromatize thing like a madman.

[00:31:53] We're going to put you on anastas all before you do that. Say hey Doc. Can you run some tests [00:32:00] on inflammatory markers homocysteine see reality proactive? No Tina, and if those are high get your inflammation under control with fish oil with curcumin with whatever you want. Yeah, whatever you want.

[00:32:17] Direct sunlight melanotan to get your chronic inflammation crew hopes it helps with inflammation to melanotan the Milano court and stimulating hormone, which melanotan is basically a synthetic version of a thousand times stronger than the stuff you producing your own body activates all four of the Milano court and receptors and all four of them suppress inflammation.

[00:32:42] That's why getting out in the beach and laying in the sun. It's so good for you. Pinterest it actually suppresses inflammation. I mean not have earned yourself recently started it like super low dose because I don't want to look like Leatherface. Yeah or but it's interesting. It's a it's something that I don't personally know a ton about [00:33:00] but you know inflammation is is bad news across the board.

[00:33:05] So the more that we can learn to eliminate that the better. Yeah 25 micrograms 20 to 25 micrograms a day is all you need of Milano tan, too. To actually see those benefits without feeling nauseous or getting tan. I mean, that's all you need. What colors? All right.  Well fair-skinned people don't get as dark right the more.

[00:33:27] Melanin. You have like me a 25 microgram dose does make me read but I've got so much melanin in my skin because I'm so dark to begin with that it activates it. Almost like a niacin flush would you say but then it gets dark but it starts out as a 9-foot nice and flush, but then it sets in and it becomes tan to me.

[00:33:46] Okay. So Mike Bear is a pistol today. He says zinc is so important for men especially for their. I knew a man who couldn't urinate.  He passed away. However, the doctor told his wife if he had [00:34:00] dietary zinc. He probably would be alive today that is astonishing that's astonishing amazing.  So I'm going to look at the wide ever hearts of the question here real quick and make sure that we covered those topics.

[00:34:19] Yeah, we talked. But that we talked about the high sensitivity estradiol test and we talked about the basic the basic blood work. That should be done you lay that out nicely and of course our position. Is that a eyes are not friend nor foe they are an arrow in the quiver to be used when they have to be and that's it and and treating them with any other.

[00:34:46] Emotion is a sign of really of not understanding science in general how I look at it as is some of the argument about like an AI being an absolutely. No way [00:35:00] shouldn't do it is the same thing as someone saying that about testosterone. Right. And so when when I hear, you know, a family practitioner or something like that is like testosterone stay away from it bad news shouldn't take it.

[00:35:16] It's the same thing as somebody saying that no one should do an aunt a sturgeon a eyes are all the terrible for you. They're the worst thing in the world the biggest things for for us as far as our position of why is even me personally if I do not take an AI, I don't feel as good a. Oh tional at my skin.

[00:35:36] I just feel like you were like compare. It's kind of silly but you're driving like a convertible and you get out of it. And you kind of just almost feel like you need a shirt or yeah, right, right you like that if I don't if my my estrogen gets too high and you've tested it often enough to know that that's what it's you.

[00:35:50] Stop taking it. Let me do an interesting, right so it but it's hard to explain an uncomfortable feeling sometimes right? So it's [00:36:00] why I've shared the convertible thing. Well, I'm not and doctors don't care about uncomfortable feelings, right? You don't know that it's hard to have that conversation our Doc's do and that's what they that's why we've had so much success as because we have a team of guys like me that have the conversation like we're having that can put those notes into the to the our system that the docs can see and they get it right and they understand that, you know, some of these probably romanticizing let's make the adjustment right and for me, I do half a milligram and test.

[00:36:31] Tuesday night and Friday night. It's sometimes it's a difference of working in the morning or in the evening sometimes for some people that you know that the sensitive to it and can kind of Zap their energy a little bit in doing the evening helps. There's all these little different tweaks that we adjust the conversation.

[00:36:49] We had at a guy recently to who's been a client for ever and he was subscribing to some of this and then he started having libido issues. So he went off the [00:37:00] AI. He started having libido issues. You start have enormous issues and I'm like, why are you doing this? He's like a I hate when you know people that start.

[00:37:08] Hey, I was doing some experimenting and I'm like out man. Don't let's we want to do that as a team. Not you on your own right, but it sounds like well because then we got to try to get you back to good but usually go out get blood work with figure out what you did and so. Long story short, we got him back on his regular AI regiment and then he's messaging me and he's like man things are everything's working back downstairs again in because a lot of folks think that if they you know AI is going to bury their estradiol they're going to have libido problems and it's not for everybody.

[00:37:39] Right? Look I feel best for my estradiol is in the lower range. I just feel dryer. I feel tighter. I feel just better and I can tell when it's the opposite so. And that's a lot for our patients and some folks don't need much AI at all and some need their High Rome incisors. We test that but we can't just throw a [00:38:00] blanket out there and everybody it's just it's Reckless.

[00:38:04] It's not proper care. You know what I mean? So I have a friend. I didn't ask him if I could ask this question, so I'm not going to use his name, but I know him very well. He doesn't he lives outside the United States. And he messaged me a couple months ago and said that he wakes up in the middle of the night between like 2 a.m.

[00:38:26] In the morning. I want to say around 2:00 a.m. In the morning. He wakes up here 2 to 6 a.m. Massive erections bigger and harder than I do normally before sex. Any idea why this is and I know what he's out he's doing he's doing 15 milligrams of test probe a day and the morning or night good question, you know it all matters because everybody metabolizes drugs different to I mean we have guys that they'll do their shot Monday morning and they get by the time they get home.

[00:38:59] They're [00:39:00] ready to chase their wife down. But we also have guys that do the shot in the. And the ready to go home at lunch to taste like that, right? So it's just a matter of how you metabolize those guys that it hits them quick typically need shots more often and there's some guys that do there's some guys it's okay to do a shot once a week.

[00:39:16] We know he doing he's doing daily. So he's doing it 15 milligrams of Test Pro per day. I'm let's sit. Let's assume he's doing it in the morning. Let's just assume he's not doing it at night and he's waking up. I have a theory about this. I've done some looking into it. And so. Um, and he so he wakes up with these fantastic erections in the middle of the night, but not not during the day when he wants his erection for being with us that way and so we of course that you will talk about our Theory.

[00:39:47] Okay. I got go-go bar theory is that when so there's two twos it. There's two issues with the directorial. There's does it work. In psychological right was the physical part of the story like that P shot comes in and [00:40:00] what we when folks get to us and they talk about like I'm like, well, what about morning erections and oh, yeah, man huge great like wake me up with it.

[00:40:08] I'm like, you don't have a physical issue. You have a psychological issue. Yes. This is what it is. This is what it is hard for people to like. Well, you know, I don't like yes. Yes, that's what it is. And I don't know like I've been stressed ever have an issue it right? Yeah stress. In any way for me personally, like if I'm super busy deadline, you know or whatever have massive amounts of things on my plate.

[00:40:32] My wife could do cartwheels in lingerie and I'm like you're bugging me right but I'm not you know, when I when my mind is relaxed all I think about sex maybe you know what I mean? So like it can shift and that's where if it fit if your stuff is working.  It's your mind and you get then you have to peel back some whether it's meditation or just figure out what's bothering you.

[00:40:54] And I've seen it where guys that just they have it from maybe they're dating someone new or there. I'll be honest with [00:41:00] you people that watch too much porn. I think develop issues because now they're comparing themselves to what they're seeing and then it I just I very good at these conversations in the coaching stuff that I do where we dig deep into some stuff and discover that that's where you know, the point being it is psychological.

[00:41:17] What is leading to. Don't know right maybe you saw some guy in the gym locker room. You're like well, maybe maybe it's just the other thing that I think happens to guys as they get older is.  We start to worry about the quality of our erections like when you went like I'll never forget it. I was on a massive cycle.

[00:41:40] and I was doing. Two grams of testosterone a gram of deca and a bunch of other stuff, but I thought that I was using enough testosterone to offset the erectile dysfunction causing effects of the DECA and I wasn't and I went to engage in sex with [00:42:00] someone new and I got an erection but it went down like really fast and then I panicked and I thought and the after that for probably a couple years.

[00:42:11] I used to think to myself one of those are going to happen again and that is becomes a self-fulfilling prophecy because you freak you freak out you start getting nervous. I had a talk with a for lumbo I did they Palumbo's the one he said though. The deck is not in you anymore. It's like been three months.

[00:42:27] It's gone. No, it's it's all your head. And that's where like I said, I've been fortunate to never have a situation like that. But I'm empathetic to the the guys that have because I hear their stories and it's digging that. It's like that one time that maybe it just didn't happen. And now it's plaguing you going into it.

[00:42:48] Right and low testosterone will leave it make it worse because you know some of the theory to is that like if my testosterone is low in my estrogens higher. I'm kind of you know, we see a lot of [00:43:00] ambivalent about sex but when my estrogen are my testosterone is higher I might go into it like. I'm dominant a man.

[00:43:07] I'm going like who I'm going to show her. Right? Right because you're confident. You just ask grown in confidence or like their peanut butter jelly, right? I mean they come together and that's where men women majority of our client base doesn't care about their bench press or their work out. I'd say physics of our clients.

[00:43:25] Don't even go to the gym they care about. The confidence the decision-making the game-changing stuff that which all has to do with testosterone, but if your estradiol and we've seen to that folks if you're estrogens, hi, it doesn't mean that you don't have to have like estrogen more than testosterone to be estrogen dominant.

[00:43:42] If you're a man to raise your yeah, it's a ratio if your estrogen is too high for what Carl needs compared to your testosterone you are going to have those same issues which also can lead. Directorial stuff which also can be psychological mean [00:44:00] estrogen almost every time you especially in I don't want to pick on women but a lot of times women men just a little less with sharing their feelings, but give me a woman who just doesn't like life.

[00:44:10] Estrogens High every single time and heard their age and also progesterone that's one that like putting a woman in her 40s or 50s and progesterone cream is Bonkers. That's what they need in their 20s when they're getting ready to make some babies not in their 50s when there yet we believe that testosterone is just about the only thing that they should be taking post menopausal or because it's going to feed estrogen anyway to it's going to feed estrogen.

[00:44:32] It's going to balance it out is what it's going to do if they come to us in our discussions at. You know that they're just they're miserable but the rest virgins up or and sometimes your estrogen is low and they they're throwing the progesterone and pregnenolone and DHEA and the estrogen patch has all the stuff and there's still a mess and he put all that away put the testosterone on but the point I kind of I digress what I'm going to is that.

[00:44:56] The psychological side of the erection piece am [00:45:00] important in the psychological side though of what estrogen can do in your body is important right that the that a massive component. If not more than 50% of it of what the presence of too much estrogen in your body, you know, and so what do I tell him?

[00:45:17] I know he trains like an animal he's super strong. He's my it, you know, he's not 60. He's in his 50s I said. Well, I would say meditate I said, when's the last time you took off from the gym and it by him replying I'm going to take off this week tells me he hasn't taken off in a very very long time, right?

[00:45:39] You know, we don't realize it but we're not only a type. But we're like a plus plus people because we not only we not only grind in our careers. We not only try to grind in our Our Lives, [00:46:00] you know, so Family Support vacationing doing all the things you want to do, but on top of that we go into the gym four five six some of us seven days a week and do stuff.

[00:46:13] That like the average person doesn't do couldn't do and couldn't do and then and then we wonder why we have this Baseline angst that we don't even notice anymore because we've been living with them for so long that it's like this. It's just this little thing down here and when you go to sleep at night, you start the night off with that angst.

[00:46:33] It dissipates within the first hour and you start going into your deep sleep modes and you're in deep sleep and then at the beginning of the. Morning, 2:00 to 6:00 a.m. You start to go into REM sleep when the brain is active and you're so relaxed. But your brain is active and you start getting your you're nocturnal tumescent erections that are designed to repair the penis.

[00:46:58] Everybody gets him in the middle of the [00:47:00] night, but yours are coming. Super powerful because you have no stress at that moment in your life. You are like you are like zero stress and your penis goes. Yeah, baby here I am but then when it comes time to go make love to your partner you you know, you just you just trained you you have all this stuff going on your life you worried about this you're worried about that and these supposed to just switch it off and get in bed.

[00:47:24] Yeah. And so thank God and guys really don't give themselves the room to chill once in a while. She today we got push notifications distracting us. We got the cell phones ring in we got the the boss on this some and it's like we're stressed out constantly. We don't even know that we're not stressed still because we're so used to being in that zone.

[00:47:45] Well, it's that it's that, you know, I was even reading a book recently. I was saying that we actually can do get addicted to that fight or flight response. Like we can get there's an addiction to that cortisol spike in that in that adrenal Spike that we kind of [00:48:00] like look, Yeah, but you know that you bring up a great point of being that like kind of alpha male a plus.

[00:48:06] I like that like Alpha plus and it's it can be taxing to shut down especially if you're not good at it. You know what I mean? Like there's certain all of us are good at there's some things like if I'm having a bad day, I might be a little short with with my kids or my wife. I might be like very Curt right, but when it comes to the bedroom time, she might be like, hey, honey, and I'm like it never affects me there.

[00:48:30] Other guys they may never lose their Wick with their kids or their wife or their co-workers or their friends, but that's where it could be. Either their spot. Right? And I think first of all saying like there's nothing wrong with you that that happens. It's just sometimes a way of maybe how you're managing your prioritizing stress or how you deal with things figuring out ways to have those self talks to unwind yourself.

[00:48:54] It's hard, you know that's in psychological side. Hormones is real and [00:49:00] we don't too often like the space that I think you and I come from originally mean bodybuilding in the fitness industry. It's all about the physical stuff. It's all about the performance and oh, yeah, I mean, let's face it.

[00:49:10] Nobody. Nobody would use Trend if it wasn't all about the physical stuff because you feel horrible on it. You know what I mean? And so when you when you in the reality is is it's probably 50%. Most that comes from the hormone stuff, right? Like if when you hear you think of women talking about their menopause and they're like all my hormones are whacked or like, you know, the hormonal side of things psychologically is so massive.

[00:49:40] And that's one of the key things because it's a quality of life. If you're angry and stressed and low self-esteem and all that all the time. It's a miserable. I don't care how big your bench press is. Yeah, and those are things that we focus on we'd like to talk about a lot more with to get people to acknowledge and notice that we're correcting a [00:50:00] quality-of-life psychologically for them as well.

[00:50:02] Not just like I'm losing a little bit of fat. Yeah, having a better libido. I want to take one last commercial break when we come back. I just want to talk about something. I read this morning about oxytocin. Okay, it's really under yeah, you're going to you're going to find this interesting stay tuned right back with more of the ReNew Life RX show.

[00:50:20] Go to renew life are x.com today to get started with a group that knows how to make you feel better. Grab a welcome back. I'm not going to belabor this. I'm just going to hit it real hard with that. So, Oxytocin is Magic especially for older guys. There's research out there that shows that oxytocin actually can make your muscles young again.

[00:50:43] This is true. And I have injected five I use of oxytocin post workout for a few years. Now. I'm out of here. My neighbor the nasal stuff now that's for the brain. That's just if you want to feel the effects in your brain. There is a place for [00:51:00] that but you got to make sure there's really oxytocin in it.

[00:51:03] There was a guy that was selling oxytocin spray.  So oxytocin is only available pharmacies. We work with Carrie. Yes, but there was a guy with selling it over the counter but it was a it was a homeopathic preparation, which means that there was no oxytocin. Okay. Oxytocin is by prescription only you have to get it through your doctor.

[00:51:24] Yeah, you know, the injectable oxytocin is called pitocin they use that to make a woman died late for pregnant. They want to bring on pregnancy faster delivery faster. And that's what I use I use pitocin I use injectable pitocin but a study just came out. Actually, it's a real it was a republication of a study that came out a couple years ago that showed that oxytocin actually gets rid of appetite and that would be the intranasal oxytocin.

[00:51:57] Okay, because you just want to affect the brain at that moment. [00:52:00] Yeah, but. What people don't understand is and I did the show there was a guy that I met through a TED Talk. I can't think of his name right now, but he wrote a book about oxytocin and all of its magic and what he said was they had did his group had done some research and they got like 200 people to agree.

[00:52:20] You ready for this to hug their family members eight times a day and they took one of these very sophisticated psychological. Scores that you can evaluate like how you like your life and you enjoying yourself and you feel hopeful and they did it at Baseline and then they did it after like two months of the study and everybody said unanimously.

[00:52:48] That they felt their lives had improved and the only thing they could point to was that they made an effort to hug someone they cared about for sure eight times a day. And so [00:53:00] guess what happens when you hug someone you care about when you hug someone that you feel a kinship to your brain squirts out oxytocin because oxytocin is the bond producing hormone.

[00:53:13] It's the hormone that makes you love it's the love hormone human. How we're supposed to be that and that was kind of my concern with if I supplemented with it that it could potentially hinder that effect in the body. Now. It doesn't hinder it. It's nothing like that. It does affect microbiome to by the way oxytocin increases the presence of a microbe that's been associated with better aging called L root are.

[00:53:44] And they are symbiotically connected to more oxytocin. You have the more L root. Are you have in your gut the more L root? Are you having to your gut the better you age? And so this is what it comes back to. Yes oxytocin [00:54:00] absolutely can suppress appetite oxytocin can also make you feel like your life is worth living but you don't have to go to a pharmacy and buy oxytocin just hug the person you love the most.

[00:54:13] Eight friggin times a day for this book that I read and I think I talked about it but becoming Supernatural by dr. Joe dispenza, but he talks about that like doing studies of people, you know, almost like when they like World Prayer day or they have those kind of things like I hope day where everybody's kind of one time everybody it like you can change that.

[00:54:35] There's these different measures that can go off but even in some of his events will do where you have that you have that intimacy. Word that we often confuse with sex and intimacy is just you know, you know you and I've never met in person but people that meet me in person. They know I hug them.

[00:54:52] All right the second time I've see you again we hug right? I'm a hugging guy, right? That's why they do it. You know, I read a study, [00:55:00] you know, I'm a Christian and I'm very involved in my church and I read to that Christians typically live longer and I think there's a part of that like loving hugging you know, too I think.

[00:55:13] Brooks my church people rightly my church people that are everybody. I had 30 people when I go to church last night, right, you know, and so I think that your point though is that also being very affectionate, you know, like my kids like there's we tuck in we hug we kissed way come home from school when they leave for school and all those same thing with my wife and I, you know, I walked out of the house.

[00:55:35] My cell phone to blow up. What's your problem? What do you mean? Well, you know like yeah, right. Yeah, I think it's not common practice because it wasn't always common practice in my house to do that affection. And I think those like you said those little steps it change your life and it makes your life worth living.

[00:55:50] I think you said it a great way. Yeah, and so those of you listening to the show today start now start today. Hug, your wife hug your children to hug. Your mom hug your dad [00:56:00] hug. You're somebody that you know forever hug someone that you care about eight times today tomorrow the next day just do it for a couple weeks.

[00:56:11] And if it's if it's BS and email me at on are at supremum radio dotnet and say Carl I did this man. I hug people all I got was a cold and it's like, okay. Okay. I think you got to be sincere. You know what I have. For like I'm hoping because I'm happy to see yeah, you know what you did and that's just how I'm wired and I'm generally a happy person like people that spend time with me.

[00:56:34] Look. Why are you so freaking happy all the time, you know it just but it's my state of mind sure I bad days but I think it that's all part of it. Like you're talking about is the hugging if I'm like hugging you out obligation. It's different. You're probably not going to release oxytocin, right?

[00:56:48] But if you're hugging like man's feels good. Yeah Embrace another. No, brother or sister loved one or whatever. It might be it is. I mean, it makes your life [00:57:00] worth living and the study that just came out that says that oxytocin suppresses hunger if you're somebody who's struggling like you're dieting and you're struggling and you feel like man, I just want to eat something.

[00:57:10] Go find your wife go find your husband and give them a real hug him a big wet kiss hug them embrace them get lost in that hug. I promise you you won't be hungry after that if the sun if the research is accurate, you're at your appetite will just be suppressed and you'll be like, oh, I don't even feel like eating anymore.

[00:57:26] So there you go. I should write a book how to lose weight without buying a damn thing. Hugs. Not drugs. Yeah, hugs not drugs. There you go. I the website is ReNew Life are x.com. Go there, you can speak directly to Adam use the coupon code shr and you will save 20% off your lab work. Let them know you heard about them here on superhuman radio.

[00:57:49] I brother have a great weekend, man, and we'll see how tomorrow tomorrow's pep. Talk you're gonna like this. Dr. Paige is going to join us tomorrow. We're going to talk about penal Lon and Epi towel [00:58:00] on the research from Russia shows that 10 to 20 day run fairly high doses. It's expensive. Who's but a 10 to 20 day run of this stuff once a year will make you live longer and reverse aging.

[00:58:15] Is it real? Is it legit? That's the one I want to I'm going to listen to you. I wanna learn about but an update on the me taking the time is in beta for in the PPC 157. I was snowboarding last week where I couldn't get on a treadmill for weeks ago. Yeah. I know the BBC the BBC 157 is really the Magic in that in that in that one.

[00:58:37] It's sighs. Yeah, awesome. I know I know either a peptide you got a Magic Eye brother. Talk to you soon. And that's all we've got for today. Thank you for watching and listening and we'll see you by tomorrow with the pep talk. Don't miss it.  Music [00:59:00] please.