[00:00:00] Carl Lanore: [00:00:00] We have an outstanding show for you today. You know, I've spent the past, I don't know, almost a month now, interviewing brilliant scientists about coven 19 and each of them has their own area of expertise. But being the guy who's interviewed them all gives me this 30,000 foot view. And when I take this 30,000 foot view, it becomes so crystal clear to me.

[00:00:26] About what we really need to know. There is so much information out there today. It's dizzying. We will, and you will not hear the name hydroxy chloroquine uttered in this show because they are fighting over something that has become politically charged, but it's not even needed. It's not needed. We learned that much from dr Luz Santi this week.

[00:00:48] Before I get started and bring on my cohost. Well now let me bring him on, hold on a second. Hold on a second. Just give me a second. This is a, an episode of the renew life RX show. So of [00:01:00] course my cohost today is Ronnie Milo. How are you doing? Running.

[00:01:04] Ronnie Milo: [00:01:04] What's up? How are you?

[00:01:05] Carl Lanore: [00:01:05] Good. I gotta give a shout out to our title sponsor.

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[00:02:12] Ronnie Milo: [00:02:12] I got to get some of those.

[00:02:13] Carl Lanore: [00:02:13] Yeah. Yeah. They're fantastic. I have to fix my shirt. It's creeping up on me. Okay. So there was just so much information out there today about COBIT 19 that it's dizzying and people are still like, they're still arguing about stuff that you don't even need to argue about. Hydroxy chloroquine is not what you want to use.

[00:02:30] And we have a, we have a good agenda to follow here to keep me on track because, you know, I'm a little ADHD. The first thing I want to say is we are not doctors.

[00:02:42] Ronnie Milo: [00:02:42] No, we stayed in a holiday and last night though.

[00:02:44] Carl Lanore: [00:02:44] Yeah, we go. But we did stay at a holiday Inn and we saved a lot of money and I saved money on with Geico.

[00:02:49] Um, but we're not doctors. But like I said at the beginning of the show, I've been interviewing some of the most brilliant minds in this space, and it's become [00:03:00] increasingly clearer and clearer every single day. What the common denominator of the most important information that we should be focusing on.

[00:03:10] In this issue is, and the first thing I want to say is why hydroxy chloroquine is not a good idea. It is. Antivirals were a mistake in treating covert 19 people are going to say, Carl, what? That's it. I'm not listed anymore. You're crazy. But what did we learn from the patients at Wu Han that got antivirals?

[00:03:31] They got out of the hospital, but when they went home, they got reinfected. Why is that Ronnie.

[00:03:37] Ronnie Milo: [00:03:37] Um, that's a good question. Uh, looks like it doesn't work, uh, in a setting that, uh, your body doesn't actually heal itself

[00:03:45] Carl Lanore: [00:03:45] by. Does it match your immune system? Doesn't learn, does it doesn't build up antibodies to the virus.

[00:03:53] It's like if you have a son and he keeps getting beat up at school. There's two ways to handle it. You teach them to defend [00:04:00] themselves or you go and fight for him. If you go and fight for him, he never learns how to defend themselves. He goes through life, never learning how to defend themselves. The immune system is the same way it mountain attack, and if you survive and you live, then that attack will never bother you again.

[00:04:16] That, that, that, uh, virus, that bacteria, this is, this is herd immunity. You live through it. And you are protected from it. And in fact, that protection is conveyed to your children. So people who have lived through covert 19 now who have offspring in the next year to five, seven years, they're going to pass those antibodies onto their, their baby.

[00:04:36] Their baby will not be susceptible to developing this virus. Right?

[00:04:40] Ronnie Milo: [00:04:40] Yeah. I mean, they're just bandaid on it. Just like, you know, the regular Western medical agenda. I mean, not speaking bad about them, but they just want to put bandaids on the issue and not fix the internal issue.

[00:04:49] Carl Lanore: [00:04:49] Well, but people are desperate, right?

[00:04:50] If you're in a hospital and you're dying. Like you want to stay alive. So if they say hydroxy chloroquine is the way to go and antiviral, you'll go, okay, I'll take it. But [00:05:00] then you run the risk of being reinfected. We learned this in Wu Han. We learned this, numerous people got out of the hospital, went back to the homes.

[00:05:08] Hey, got covert 19 all over again. That's horrible. Right. That's horrible. Okay. And we're gonna stay with the, I am not gonna I have, when I published the show today, every single study backing up every S every single assertion, every doc that I'm going to connect on the show will be there for those of you who want to see where I'm coming up with this nonsense, okay?

[00:05:30] So we know that the elderly population is at most risk, right? We also know that people who have additional, uh, uh, illnesses create co-morbidities, they like, they like to call it, right? And so we're going to address the elderly first. We also are aware that elderly people develop more senescent cells. Now, why is that important?

[00:05:57] We're going to talk about in a second. [00:06:00] But the reality is that all of the diseases associated with aging. Uh, or chronological aging, uh, are associated with the accumulation of senescent cells. In fact, these cells, actually a causative, it shows in studies to the pathologies that we consider diseases of aging, which are, you know, heart failure, heart disease, diabetes, arthrosclerosis, kidney failure.

[00:06:24] All these diseases can be linked back. To the continuous burden of senescent cells, and for those of you who've never heard of senescent cells, we've talked a lot about them over the years. These are zombie cells. Every cell in your body has an expiration date on it. The process of these cells disappearing and being replaced by healthy cells.

[00:06:45] This cell turnover is driven by a phenomenon called apoptosis. Apoptosis is when the cell dies on time when cells don't die on time. They go into this suspended animation, a [00:07:00] state, and then they start to produce inflammatory cytokines and other inflammatory, uh, molecules that actually make the cells around them sick, okay?

[00:07:11] These cells there, they've been called zombie cells because they just linger on, but they don't contribute anything. If anything, they make things worse. Well, senescent cells are being tagged with the reason. That aging is seeing the way it is. We can't walk anymore. We develop diseases, we lose a Mo muscle, muscles weaken and, and don't function anymore.

[00:07:35] Even said, essence cells are even implicated in the development of Alzheimer's disease. There's no doubt about it. Okay? So we just remember this about the senescent cells for a second.

[00:07:45] Ronnie Milo: [00:07:45] Okay. Telomeres? Well,

[00:07:48] Carl Lanore: [00:07:48] shrinking telomeres has been. Kind of baffled as a reason for senescent cell development because we have people who have very short telomeres, but they don't have senescent cells, but they do play [00:08:00] a role.

[00:08:00] There's other cofactors, including those shorter telomeres that seem to. Cause cells to become rogue senescent cells. But really the one thing we know for sure that causes a senescent cell to S to linger on the cell not to disappear when it was supposed to, is having  continuously turned on. Now we can look to this standard American diet and the standard American today, if you see obese people, they are probably eating around the clock.

[00:08:37] They eating a lot of food. They stay up late, they eat before bed. They have to wake up at three o'clock in the morning to eat something because they or they can't go back to sleep. This is turning mTOR on all the time. The body was never designed to be that way. It was supposed to oscillate, you know, M Tor autophagy, M tall autophagy, build, remove, build, remove.

[00:08:55] And these ebbs and flows are how we are supposed to function. [00:09:00] But when M is turned on all the time. We know that this is what contributes. This is domino, one of what makes a cell become a senescent cells or zombie cell. Now those of you thinking, why are we talking about this? This is anti aging. No, because say in essence, cells produce a unique, undeniable opportunity for the Cobra 19 virus.

[00:09:24] Not only to infiltrate you, but to replicate. Stay with me here. Glucose to say gulling has also been implicated on triggering and triggering senescent cell proliferation. Can you tell, I'm excited. Let me slow down. I did an interview in 2007 with a doctor from the Albert Einstein Stein school of medicine who published the paper, and the paper simply said, glucose signaling is what triggers cellular senescence.

[00:09:53] And he was onto something because glucose signaling plays a role. In helping to drive M [00:10:00] Tor as well. So people who are old, they accumulate a lot of senescent cells, but also diabetics. Type two diabetics accumulate a lot of senescent cells. And we see this in their population because they suffer from age related diseases at much younger ages, 30 and 40 years old.

[00:10:22] Alzheimer's disease, heart problems, high blood pressure. A type two type two diabetes is, is, is the cause, not one of the co-morbidities in reality, but kidney failure, cancers, dementia. I mean, the list goes on and on 30 and 40 they're developing these diseases associated with. Old age. Why is that? Because they develop more senescent cells earlier in life.

[00:10:49] Right?

[00:10:50] Ronnie Milo: [00:10:50] But also to look in into, um, you know, the massive increase of insulin production in the body that's going to go ahead and increase the senescent cells are replicated twice the rate

[00:11:00] [00:10:59] Carl Lanore: [00:10:59] because it, because every body builder knows that insulin is watt. Anabolic anabolic, and when we hear the word anabolic, we're talking about turning on mTOR.

[00:11:09] And when we talk about turning on mTOR for continuously long periods of time, like people eat constantly around the clock, we're talking about literally doing everything you can to manufacture more senescent cells in your body. And that is why people who have type two type two diabetes and are obese.

[00:11:33] Have the same Coborn biddies that elderly people do when they get this virus. They have heart disease, they have a nonalcoholic fatty liver disease. They have high blood pressure, dyslipidemia, dementia, cancer, and so on and so forth. Now, rebirth. God, I'm sorry. Yeah.

[00:11:50] Ronnie Milo: [00:11:50] The body is primed to replicate this, this, this virus.

[00:11:53] If you know, if you, if

[00:11:55] Carl Lanore: [00:11:55] you don't meet. There's

[00:11:56] Ronnie Milo: [00:11:56] so many different cofactors contributing to the environment that makes [00:12:00] the, the virus grow at such a quick rate. That's pretty much you're, you're giving

[00:12:05] Carl Lanore: [00:12:05] the

[00:12:05] Ronnie Milo: [00:12:05] body's fuel, right? You're giving the body fuel Wharf, uh, fuel on the fire to fire is going to burn hotter and longer, and that's where you start to see, uh, the morbidity rate.

[00:12:14] Go up with these, uh, these diseases.

[00:12:17] Carl Lanore: [00:12:17] Absolutely. And you're right, because, because, um. Senescent cells will harness all the things that help quiescent cells survive, and that's what helps keep them alive as you're pointing out here. Now, I want to put one other caveat in here because people are thinking, I'm just talking about obese people.

[00:12:43] Uh, obesity is often an outcome of type two diabetes, but not always. We, I know people who are. You would look at them. A woman, she's a size four, size three and she, her form factor is, wow, she's got a great figure, but she, her blood [00:13:00] sugar is in the 120 130 it's fast blood sugar. Why? Because it's not about obesity.

[00:13:07] It's about insulin resistance at this point in time, and you don't have to be fat to be insulin resistant. So I'm going to tell people out there who think, well, I'm not obese. I don't have to worry about it, and they've never checked their blood sugar and they don't even know if their blood sugar is elevated all the time.

[00:13:25] Uh, you may be at risk. Some of the telltale signs. I just had a conversation with a guy who called me the other day and was having some problems, and he told me, we were talking about fasting, and I says, I've gone three days without eating all I do, you know, maybe twice a year. How do you do that? He said.

[00:13:44] I says, well, he does does does your appetite. He says, if I go three or four hours without a meal, I start to get the shakes. I get the sweats. I says, well, sounds to me like you are starting to develop insulin resistance. That's one of the telltale signs, right? Yeah, yeah,

[00:13:58] Ronnie Milo: [00:13:58] yeah. Increase in decreasing the [00:14:00] blood sugar will release ghrelin.

[00:14:03] Okay. Intermittent fasting will release leptin, which is a society, drug or society hormones that's you don't want to eat when you're fasting.

[00:14:11] Carl Lanore: [00:14:11] So senescent cells are targeted by covert 19 for viral replication. And here is why the senescent cells produce a great opportunity on two different levels for this virus.

[00:14:24] And we know from doctors I've interviewed this week that this virus takes advantage of senescent cells. The more senescent cells you have, the greater likelihood that you will contract the virus if you come in contact with it. And the greater likelihood you will die from the virus. This is, this is the magic between age, chronological, age and death from this virus or comorbidities and death from this virus.

[00:14:52] This is it. So we've all heard that covert 19 enters through the angiotensin two receptor that was out in the news for [00:15:00] awhile and many people talked about how taking a Arby's. Uh, could block the receptor and protect them against getting this virus. Do you recall that? Yeah,

[00:15:11] Ronnie Milo: [00:15:11] absolutely.

[00:15:13] Carl Lanore: [00:15:13] Here, Matt Andry, who is my personal physician and is gracing us and listening to this show today, just said hypoglycemia and postprandial fatigue are two of the best symptom indicators for hyperinsulinemia.

[00:15:28] So if you suffer from eating a meal and having to go to sleep or. If you haven't had a meal in two or three hours and you're starting to get light-headed, anxiety, sweats, tremor, you are already in this category of people at greater risk. So that's, that's great. Thank you, Matt. And thanks for being here too, by the way.

[00:15:52] Um, so let me get back to where we were. [00:16:00] Uh, I'm sorry. I am trying to produce the video at the same time. So here we are. Uh, let's see here. Yeah. So senescent cells offer a unique opportunity for covert 19, because they actually have more angiotensin too. Receptors on them. In fact, there are several studies that show that angiotensin two angiotensin one has a protective effect.

[00:16:27] Angiotensin two actually increases the, what we considered, uh, aging to the vasculature, for instance. Okay. How does it do this? It does this because angiotensin two helps not only produce the, uh, senescent cell. But it populates the senescent cell with more of the angio to angiotensin two receptors to keep them in that senescent state.

[00:17:00] [00:16:59] And he said, you on angiotensin two Matt, you're the best man. I got to tell you, I worked on this show all last night and today, and I just want to get everything out in a, in a concise manner where everybody can understand it and go, okay, now we know what we have to do. So. The next point here that I want to bring up is angiotensin two receptor is implicated in the development of senescent cells.

[00:17:24] As a result, there are more receptors on the senescent cell, which means greater opportunity for the coven 19 virus to get into that cell. But there's another thing unique about that cell. It's a zombie cell. It's like one of those movies where they plant the host in a human and the human and walks around and the, and the, and the, and the being is eating them from inside and then eventually bursts out these senescent cells, the zombie cells, the, the COBIT 19 virus actually not only gets in through them, but they [00:18:00] are better suited for the virus to help replicate.

[00:18:03] They literally turn into viral replication factories. And one of the ways they do this is when people have  cause they eating a lot of foods, they, they, they, they obese people. And so on. mTOR is turned on all the time. And it M Tor regulate protein synthesis. And it not only increases. The number of senescent cells, but  required for this virus to replicate the rep.

[00:18:37] The virus is housed in a protein shell. So the cell through mTOR starts to produce more viruses because it has all the building blocks there, the viruses in there, and the virus is replicating and it produces the shell out of protein and then releases it. So. M Tor and the senescent cell [00:19:00] together literally become a factory for producing this virus.

[00:19:05] Now you, you want to comment in here so I can slow down and think for a second?

[00:19:11] Ronnie Milo: [00:19:11] Now

[00:19:12] Carl Lanore: [00:19:12] I'm rolling. Okay.

[00:19:17] So what we learned this week from dr Liz Santi. Uh, what she's going to, we're going to talk about some of his science later in the show is the more senescent cells you have, the higher likelihood you can contract the virus if exposed. And the higher your risk of death. And this we know for sure, and the goal has to be to reduce the number of senescent cells, the burden to your body and as quickly as possible.

[00:19:45] Now, the CDC is telling people there's nothing you can do right now. Dietarily or supplement wise. That's not true. It's really not true. And in fact, the answers to solving this problem are things [00:20:00] that we are actually using today. Many of them are right under our nose. So what we're going to do is we're going to take a quick commercial break, and when we come back and we're going to talk to you about how you can actually produce.

[00:20:14] And effect that will not only help you resist getting the virus, but resist succumbing to it. We're going to take one quick commercial break. Stay with me. I promise you this will be worthwhile. Pass the show around to everybody you love. We'll be right back.

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[00:24:28] Hi, I'm going to take a breakfast. You know, I feel this. I feel this sense of urgency. I feel like, like everyone is being distracted by all of this information. Some of it good, some of it bad, but it's like what we're arguing about all this stuff for this nebulous stuff out there when we really do know.

[00:24:49] How to stop this virus from hurting us. But the problem is, you know, we have a limited amount of time to actually get this information out. So, [00:25:00] and that's why I kind of feel a little hurried about this, but I'm going to just slow down now. Okay. So we've established here a clear line that a senescent cells are opportunistically exploited by this virus.

[00:25:15] B. Elderly people and people who have metabolic disorder, metabolic syndrome have the highest accumulation of these senescent cells. And so those two points are undeniable. And again, all of the research that I've read through to prepare for this show today will be linked in the show post on my website when we publish it.

[00:25:38] So what can we do? Well, the first thing you can do, believe it or not, is start looking at resistance training. This is a, an unknown study that I've mentioned on my show over the year. Well, the past year and a half was published last year and it showed that a single bout of resistance [00:26:00] training, which probably, I think it was like an hour, and it was w they used a fairly fit people, so they, they were really hitting it hard, but not heroic.

[00:26:12] A single bout of resistance training. Eliminated 42% of senescent cells in muscle tissue as shown through . Biopsy. They did a biopsy before they assayed the percentage of muscle of senescent cells in muscle. They did a biopsy after the workout. They actually did a biopsy every day for the next two days.

[00:26:37] They stopped that their day, and they showed that not only did it eliminate 42% of senescent cells like that, but those cells didn't return. For the 48 hours that they continue to do punch biopsies. If they would have continued longer, maybe they would've saw that those senescent cells didn't come back for longer.

[00:26:57] Right. The most important thing is the impact of a [00:27:00] single bout of resistance trading. So those of you who are out there now training three days a week, whether it's at home now because we're sequestered, or when you're at the gym, you're actually building up protection against this type of opportunistic virus because you have less senescent cells than the average American out there, far less.

[00:27:20] And let's remember something even in non-trained individuals. Muscle makes up between 34 and 47% of your mass of your body weight. Now, those of us who carry, you know, I probably am maybe around 13% maybe 14% body fat right now, so it actually is a greater ratio, but muscle is a substantial amount of your being.

[00:27:47] Being able to remove 42% of senescent cells in an hour. That's astonishing to me and that seems to me like, okay, [00:28:00] that's the first thing I need to start doing. What do you think of,

[00:28:03] Ronnie Milo: [00:28:03] yeah, I mean, going back to your show, you did earlier, I forgot what doctor you interviewed about the resistance training in immune function.

[00:28:10] Talking about anaerobic and aerobic activity, a anaerobic is shown to increase more immune function than actual aerobic activity, and then it's all about the duration too. Also too is, you know, when you do strength training or resistance training, uh, your body produces a thing called phagocytosis and that will actually ingest bacteria or other phagocytes that are in the system.

[00:28:34] So basically you're, you're, you're putting your body in a position that it's going to eat bad cells, bad stuff, right? Illnesses, bacteria, viruses in that nature. So it's very, very beneficial. Um, for to do some kind of resistance training. Um, you know, in short bowels.

[00:28:51] Carl Lanore: [00:28:51] Okay, so that's number one. Start training.

[00:28:54] Get out in the backyard, do pushups, do body weight squats, do whatever you have to do. Feel like you worked hard. Do that [00:29:00] for an hour, and that's going to help you start to downregulate the accumulation of senescent cells. Number two, dietary strategies. Okay. Intermittent fasting, a strict vegan diet or a strict ketogenic diet.

[00:29:14] All three of these have been shown to interrupt . Remember we talked about senescent cells require MTR to be turned on for long periods of time to become senescent cells. If your body is going through the normal ebb and flow of of protein synthesis, and then autophagy and protein synthesis and autophagy, you don't have this problem, but if you have somebody.

[00:29:37] Who eats around the clock and you've got  turned on all the time. You have more senescent cells. These three dietary strategies have all been shown in science to both interrupt . Okay. And actually, uh, intermittent fasting and ketogenic diet had been studied and shown to reduce the load of, uh, [00:30:00] senescent cells in the body.

[00:30:02] So these are two great dietary strategies. And, and. Do you want to do these forever? Like I might do vegan for a couple months. What the hell? I'm not going to do it long enough to get a a nutrient deficiency, but I would do it for a couple of months if I was a frontline worker. I don't know. You may get a little lightheaded too, but you know, if you try to intimate and fasting or one of these dietary strategies, if you're, you're a frontline worker, you're a hospital worker and you know that you're constantly reducing.

[00:30:30] The opportunity for this virus to hurt you. You can do these for a few months until we're out of the woods with this.

[00:30:37] Ronnie Milo: [00:30:37] That's protecting yourself. You know what I mean? Being preventative.

[00:30:40] Carl Lanore: [00:30:40] I mean, you're not going to wear a mask for the rest of your life. You may are wearing it right now. You could do one of these dietary approaches for, for for a while and see what happens.

[00:30:47] Okay? Yeah, and there are supplements that can help as well. These supplements have all been shown to turn off . Now not turn it off [00:31:00] indefinitely, but turn it off when you supplement with it. Resveratrol, quercitin, alpha lipoic acid and the amino acids, histidine, lysine, and threonine have all been shown to inhibit mTOR.

[00:31:11] Now, resveratrol and alpha lipoic acid, those are no brainers. Why? Because they actually control blood sugar and that goes back to high blood sugar all the time. Hi, M Tor. High accumulation of senescent cells. So they work by actually helping you manage blood sugar better. Quercitin has been shown in a study alongside , which is a very weak, um, uh, oncology drug.

[00:31:40] It's a, uh, chemotherapy to also re reduce senescent cells by itself or in conjunction with the saddening. So these are things that you can include in your diet for a while, but now. That will help you at least not accumulate more new senescent cells. [00:32:00] And if you do them with intimate and fun, I mean, I'm fast if I haven't eaten since six o'clock yesterday.

[00:32:04] That's also why I'm a little wired because I'm running on ketones right now. I get, I get high from ketones. I actually feel euphoric. You and me both. In fact, there are times where I don't eat because I don't want this feeling to go away. But then I have to, I think while I got to go home and eat later, so I'll, you know, I'll eat two meals for that day and that's it.

[00:32:22] But I love feeling this way. I just feel clear and energized. Anyway, so these supplements are beneficial as well. And then I'm sorry.

[00:32:32] Ronnie Milo: [00:32:32] Yeah, the touch on that lysine, I think there's, I've seen studies that lysine is actually used as an antiviral to prevent HIV one,

[00:32:39] Carl Lanore: [00:32:39] which is fever blisters, right? Yeah, exactly, exactly.

[00:32:44] No, not

[00:32:45] Ronnie Milo: [00:32:45] very important. It was detoxify the liver as well. You know, you want the liver to be optimal.

[00:32:50] Carl Lanore: [00:32:50] And personally I use our ally because they corralled. It has been shown that the, our ally is where the blood sugar management really comes from. [00:33:00] The, the the not the L L L a portion. So when you take alpha lipoic acid, it's 50 50.

[00:33:05] If you just think our aloe, you're going to get greater benefits, I believe with that type of blood sugar management that's leading to a reduction in and producing more senescent cells. But there are some drugs and two of them have actually been approved by the FDA specifically to vanquish, and I use that word specifically, a zipper, myosin Z pack.

[00:33:29] He's been shown to eliminate almost 100% of the senescent cells in your body after one five die Daisy pack bout. Think about that. I mean, when I saw this, I actually thought I was going to call Matt and say, Matt, maybe I should do this once a quarter. Maybe we should all be doing this once a quarter, but, but another one is doxycyclin, which is prescribed for acne, and people take this for long periods.

[00:33:54] Some people take it six months, a year at a time. It's very, very safe. And then of course, my favorite [00:34:00] rapid myosin, which I take six milligrams twice a month. But that has been shown to also inhibit mTOR. But we have an anecdotal story that I'm going to let you tell about one of the patients on the, uh, what was the name of the cruise ship that first got hit with the virus?

[00:34:19] Ronnie Milo: [00:34:19] Uh, the

[00:34:19] Carl Lanore: [00:34:19] star. The diamonds, the diamond, the blue, the diamond something. Yeah, the diamond. Yeah. So, so that was the ship that had like 300 cases of, of covert that we were keeping off. And we were like, we didn't know what to do with it. Just leave them out there for awhile. They went back to China. They went to China or Japan, I want to say they went back.

[00:34:37] Yeah. So tell the story about one of the patients on there.

[00:34:42] Ronnie Milo: [00:34:42] Yeah. So you sent me an article as one of them, but the New York post about this gentleman that was on the, uh, the

[00:34:47] Carl Lanore: [00:34:47] cruise ship,

[00:34:48] Ronnie Milo: [00:34:48] and, uh, they would do random testing. They would come to their, um, their suites and they would test them for the, for the SIU cov ID.

[00:34:55] Uh, this gentleman actually tested positive for the cov [00:35:00] ID, but looking into his background, he was a. Recipient of a kidney transplant and he was possibly on, they don't say what drug, but we could probably think it was rapid myosin. Um, he didn't have any symptoms of it. His wife had some symptoms of it.

[00:35:16] She had isolated, uh, they retested him again. He did still test positive, but he had no, um. No, uh, you know, uh, symptoms of it. He didn't feel bad. He just tested positive for it. So they let him come home, I believe, to, to his house to sell quarantine. They kept his wife in Japan because she was having some symptoms of it.

[00:35:35] Carl Lanore: [00:35:35] Yeah, she was,

[00:35:37] Ronnie Milo: [00:35:37] yeah. They, they retested them again and he was still positive

[00:35:40] Carl Lanore: [00:35:40] with no, and he did have, so at the onset, he ran up a low grade fever for one day.

[00:35:49] Ronnie Milo: [00:35:49] Yeah. For one day. And then he said he got up in the morning and he fell.

[00:35:52] Carl Lanore: [00:35:52] Felt fine. So, you know, this is anecdotal and I, you know, all this study is, is coordinated [00:36:00] anecdotes.

[00:36:01] You know, one person has this effect. It's an anecdote, you know, 200 people have this effect in a controlled environment where we're tracking everything. Now it's research, but most anecdotes are the reasons for studies. We see these anecdotes go, gee, I wonder if that works with other people that way when we do a study.

[00:36:21] So this plays right into this idea that because he had fewer he, so as a kidney transplant patient, you take an anti-rejection drug every single day, and the most popular anti-rejection drug is rapid myosin because it really has the least side effects. There are other drugs that they use, but some of them have really horrible side effects.

[00:36:43] And then there's. Methyl prednisone, which is horrible that they'll use in conjunction with rapamycin, but usually not by itself. And so most kidney transplant patients get rapid myosin. It's well tolerated, but they take [00:37:00] usually 10 to 12 milligrams a day ongoing. So this guy probably has no. Zero like maybe he's got like, you know what?

[00:37:10] 1,000 senescent cells. So he developed a little fever, but then it went away. Right. This is very promising in the, in the context of what we're talking about here.

[00:37:20] Ronnie Milo: [00:37:20] Cause I bumped into her so it doesn't give him the fuel to, to replicate it. Yeah.

[00:37:26] Carl Lanore: [00:37:26] And you know, a rapid myosin has a three day half-life. So it's, it's, it lingers that sticks around it.

[00:37:33] The dose is build on each other day after day until about the third day, and then it just, it stays there. Uh, so yeah, he probably had a couple, uh, brand new senescent cells that, uh, were just around in time to give him a little fever, but they were gone the next day, and that was it.

[00:37:49] Ronnie Milo: [00:37:49] Nobody said, we're not going to handle this no more.

[00:37:50] We're going to take care of this.

[00:37:52] Carl Lanore: [00:37:52] Yeah. So, so this is, uh, this is a very exciting area of science that we know. He says, I know you hate [00:38:00] it. Yeah, I know a man. Yeah. But you know, it's, um, it's a very, very exciting area of science that no one is talking about. Everybody's fighting hydroxy chloroquine hydroxy chloroquine is a horrible idea.

[00:38:14] It's not going to help people in the long run. It may get them out of the hospital, but they will end up, uh, possibly getting reinfected. Yes. And of course. Metformin inhibits mTOR, of course, as well. And we will going to include that in our discussion, but I couldn't find any studies that directly tied it to the elimination of senescent cells and both, uh, both, uh, a zipper, a myosin.

[00:38:45] And, um, what's the other one I just said. The acne drug, uh, Zithromycin and doxycyclin have been approved by the FDA to eliminate senescent cells. [00:39:00] So it's not like as though you even have to prescribe it off, uh, off label because it's been approved for this purpose. You can say, I want to get rid of this person.

[00:39:09] Senescent cells. Yeah, he's got covert too, but I want to focus on the senescent cells so you could prescribe it.

[00:39:15] Ronnie Milo: [00:39:15] Also to want to touch on peptide therapy

[00:39:17] Carl Lanore: [00:39:17] therapy. Actually

[00:39:19] Ronnie Milo: [00:39:19] you can senescent cells, right? Did you integrals almost agree to gods? Yes. We use those at the clinic, obviously to help to decrease the senescent cells.

[00:39:28] So that's one point I wanted to point out.

[00:39:30] Carl Lanore: [00:39:30] And how do they work that way? I would imagine Motzy would help because mot DSC actually helped through regulate. Um. Blood sugar levels, and I would say anything that helps you with blood sugar levels is going to be beneficial. In fact, I was just thinking of a dr Andrey.

[00:39:46] All right. Of course, I know that he uses that. Um, uh, what's that injectable? Um, Oh God, I can't, what is it? Lindy and peptide

[00:39:57] Ronnie Milo: [00:39:57] and helps control blood sugars. Well,

[00:39:59] Carl Lanore: [00:39:59] okay. [00:40:00] I'm trying to think of the one. Victoza. What's Victoza? What is Matt? You're listening. What is Victoza? It's, um. I can't think of the peptide it is, but that's another one.

[00:40:10] These, these drugs would be good for people who had diabetic, um, well, starting to develop insulin resistance to help regulate their blood sugar because, because again, alpha lipoic acid resveratrol, they work by regulating blood sugar and turning, helping to turn off M Tor. So

[00:40:30] Ronnie Milo: [00:40:30] berberine does the same as sex by lowering blood sugar.

[00:40:33] Carl Lanore: [00:40:33] I forgot that one. Thank you. Berberine is another one. Absolutely. Absolutely. That's another supplement that you could take. Um, what I wanna do is take our last commercial break and when we come back, I want to talk about what if you already have COBIT GLP one analogs. Thank you, Matt. Matt, thank you GLP analogs.

[00:40:53] Uh, I want to take our last commercial break cause this is where the really exciting information comes in. And this is something that I have to thank [00:41:00] dr LA Santi. And, uh, also. Uh, dr , uh, for teaching me about over the years. Uh, and this is going to help a lot of people who are like, look, I'm a nurse. I'm a fireman.

[00:41:13] Uh, you know, I'm out there on the front lines. I can't stay home. I'm an essential worker. I have to go to work, but it freaks me out. There's an answer and it's a very simple answer. Stay

[00:41:23] Ronnie Milo: [00:41:23] tuned.

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[00:46:06] [00:46:00] Welcome back to this special episode of the renew life RX show. If you're thinking about hormone replacement therapy. Regardless of where you are in the country, you just have to reach out to Ronnie Milo or one of the guys, gals over at me, new life rx.com and Dave mentioned Supima radio. You'll save like 20% off your labs.

[00:46:29] So that's something I'm also, I want to get back to. So when dr Andrey messaged that the GOP one analog, he said, Trulicity OSMP by ADA Bydureon or the others. He also messaged me two studies that show that Metformin does in fact inhibit

[00:46:54] cells. Well, we know it inhibits, uh, uh, I knew that, but I [00:47:00] couldn't find any that specifically showed an effect on senescent cells and he just sent me two studies. I'll include those when I post the show. So what have you already have. Covert 19 what would you do? What would you do? What would I do? Yeah,

[00:47:20] Ronnie Milo: [00:47:20] take care of it.

[00:47:21] Sit around on my body very long.

[00:47:23] Carl Lanore: [00:47:23] So first thing I would do is avoid any antivirals. If we learned anything from the people in Wu Han, the people who got the antivirals, came home, got sick again, and went back to the hospital. You need something that will allow you to survive, but allow your immune system to learn.

[00:47:42] This virus so that it can produce the appropriate antibodies so you're never at risk again. And if you're young enough, so you, when you have children that you can pass down these antibodies to your offspring so that they don't have to worry about this virus. That's number one. Number two, if you're on the front [00:48:00] lines, uh, I would ask my physician to prescribe a Z pack and take it for the requisite.

[00:48:05] Five days is described. If you think that you have contracted this. That's dr Luz Santhi talked about numerous studies that show that that knocks it out and we don't even have to team it up with anything else. Or if you are worried about getting it, then perhaps just ask your doctor to provide you with a doxycyclin a prescription.

[00:48:29] People take that for six months at a time without any problems. Arithromycin also, someone told me, I said to Alyssa the other day, well, you know, you build up. A resistance to a Zithromycin. That's not true. It's a very weak antibiotic, actually. Eh, they don't understand a lot of these. So, so with dr Luz Santhi talked about, um, on the show this week was physicians are afraid to, or don't even think of things that are not antivirals in this situation.

[00:48:58] But the reason that they need to think [00:49:00] about doxycyclin and a zipped or myosin is because they inhibit mTOR. And this virus needs M Tor to replicate any  inhibition is going to make this virus die out as if the myosin does not show any evidence of building up drug resistance, nor does doxycyclin. And we're talking about literally pennies a day.

[00:49:27] You know, doxycyclin has been in use as a six month to one year treatment of, of acne. And it's been proven to be very, very safe. We all have taken Z-Pak from time to time, so we know that they're safe. Both of these are popular antibiotics. They've been approved as treatments to reduce senescent cells by the FDA.

[00:49:47] They cost literally pennies a day, and there's no shortage of them. They're in great demand because they're both generic drugs. So why are we fighting about all this other nonsense? [00:50:00] Uh, when we have the opportunity to treat this, uh, virus, protect people from dying from it, and even protect people on the front line from contracting it in the first place.

[00:50:11] And this, this is just, to me, it's just crazy. It's just crazy. What are your thoughts.

[00:50:19] Ronnie Milo: [00:50:19] Yeah, I think there's a, there's a lot going on, right? There's a lot of smoke and a lot of people can't see through the smoke, and therefore they're trying to do the best that they possibly can, but they're not seeing through the smoke, uh, to understand what we're, what you're trying to, uh, communicate with everybody.

[00:50:34] So I think, um. As the agenda will shift, you might start to see a lot of physicians starting to call out on those different medications.

[00:50:43] Carl Lanore: [00:50:43] Uh, Jeff Clifton answers asks a very intelligent question if you're paying attention. He said, so would you reduce Matthias? And if you contracted it at  and or Lucene.

[00:50:53] Because let's remember, Lucy turns on mTOR, and I'm going to tell you no one. I'm going to tell you why, uh, come to [00:51:00] my website. If the show's posted, read this study on one bout of resistance training. Uh, ameliorating 48% of senescent cells in muscle. They did something very smart in this study. They put one group of guys on a low protein diet and one group group of guys on a high protein diet and high protein diet was one gram of protein per pound of body weight.

[00:51:23] And it still got rid of the senescent cells. And why is that? Because turning on mTOR and turning it off is where the magic is having M turned on all the time because all you do is eat all day long is where the problems occur. So no, I wouldn't reduce my red meat intake. Um, I wouldn't reduce my dairy intake, but I am a fan of intimate and fasting and I still maintain a.

[00:51:49] Good. I mean, I'm 232 pounds right now, and I'm probably 13 or 14% body fat. I maintain muscle without really having to work hard. Uh, and I, and I, so [00:52:00] I'm not worried about losing muscle, and I'm not worried about cutting these foods out because I have plenty of opportunity for autophagy and insulin sensitivity to step be established in my body when I'm fasting.

[00:52:12] So, no, I wouldn't, I wouldn't now if I was, if I was. An obese person who is eating all the time. And then I would start to focus on fixing my insulin resistance. And this is a wake up call to everybody out there, all of you who used to laugh at people like Milo and me because we carry our food with us and where we're, where we're militant about getting good sleep.

[00:52:38] And we're militant about getting to the gym. Well, none of us. We're not running and look for hand sanitizer and masks. I'm not, I don't care about them. Yeah. Yeah. So, so that's the trade off. You either either do the work now you do it later. So I, this is a wake up call to every American to get your shit together.

[00:52:58] So the next pandemic, you're [00:53:00] not one of the vulnerable people because I got news for you. Come the end of the month. If they opened the country back up, all people in sick people are still going to have to stay home. Mark my words . Right.

[00:53:10] Ronnie Milo: [00:53:10] I think I want to touch a little bit on Jeff's question about, um, assignee.

[00:53:13] Um, I think he might be thinking about Lucy, would you eliminate dilution if you can

[00:53:19] Carl Lanore: [00:53:19] track to this over? No, I said that I said that. No, because I, because I, I would, first of all, if I contracted it, I would get a Z pack right away. That's the first thing I would do. I would just take a Z pack and I already have rap myosin, so I'd probably take six milligrams or wrap rapid bias in a couple of days, and that would be, it.

[00:53:38] And my body would build up the antibodies and I would, I wouldn't get it anymore. That would be it. Look at the guy. He's still testing positive, but he has no symptoms. Right. So his body is prepared for it. Now, a couple of other good questions. Let's see here. Um, I thought it was due to the  for activity of Z-Pak and H C Q.

[00:54:00] [00:54:00] To show zinc in the cell to shut off RNA transcription. You know what? Not according to, uh, dr Luz Santi. Or maybe he did say that. You know what? I don't know. All I know is Z-Pak. Definitely protects you from this virus. And dr LA Santhi said, it's because it reduces the, uh, load of senescent cells, and he's like,

[00:54:25] I mean, he's got a list of credentials that goes beyond, uh, anything I can list for you right now. But Aiden, go and listen to the show I did with dr Liz Santhi this week. And, and maybe he, uh, he clarify that for you. A big Bowzer says, are you going to suggest vitamin C? Absolutely not. No. No. And I, you know, and I know they're using intravenous vitamin C and all that, and I take, I take one to two grams of vitamin C already, but no vitamin C has no effect on senescent cells.

[00:54:53] And you know, all, all this stuff, vitamin C and hydroxy core Quinn, it's all up [00:55:00] here. But down here at the pinnacle, the lowest common denominator is senescent cells. And if you focus on things that stop the replication of senescent cells and inhibits. Protein synthesis periodically you will kill this virus.

[00:55:15] So no, I'm not going to say that. Uh, yeah. Preach Carl. The Holy Trinity. Good sleep, good food, and some exercise. Absolutely more Americans. You know what? I'm going to say something and I may piss people off, but I've come to the occlusion that if you are, remember I was a 330 pound fat ass  okay? So I can say this.

[00:55:41] If you're one of them, you're a, you're unpatriotic because you're putting this country under a great load because you are going to get sick. You're not going to be productive. We're going to have to pay for you for all your, your, your treatments and therapies. And more importantly, you're the reason that we can't go out right now.

[00:55:58] You're one of them. [00:56:00] So, you know, I'm tired of it. I'm tired of people just abdicating their responsibility to take care of themselves. And expecting how health care is not going to save you. It's not going to save you. The only thing is gonna save you is to take responsibility for your own health, put in a couple of years and get yourself together.

[00:56:19] Cause that's how long it will take.

[00:56:22] Ronnie Milo: [00:56:22] Well, I mean on that note too is since we, everybody's stuck inside and everything, we've seen a lot of people outside now doing kind of physical activity, whether walking, biking or something, which is good. You know, I encourage that. Um, you know, but why, why does that take a pandemic to start to figure out how to fix yourself?

[00:56:38] Right? It should be an everyday thing. You know what I mean? And, and I do applaud these people for trying to get out, but once we returned back to normal, they're going to go back to normal. Are they going to continue the exercise process? You know what I mean? So it's very frustrating.

[00:56:51] Carl Lanore: [00:56:51] It is. It is because we, those of us who, the only money I spend on healthcare is, is testing my blood.

[00:57:00] [00:56:59] And, and in fact, I go as many of the people who watch the show knows and listen to my podcast. I go to any tablets, any lab test now, and I take money out of my own pocket to test things like iron levels. I don't even ask for prescriptions to go to labs anymore. I'm a $44 other people buy a $70 bottle of wine and think nothing of it.

[00:57:19] I go pay $45 for a lab work, lab work. I'm like, happy to do that. Well,

[00:57:24] Ronnie Milo: [00:57:24] people ask me all the time, you know, how much you spend on your health? And I said, no, I spent about 3000 to $5,000 a month on my health, you know, when they're training, nutrition, supplementation, you know, medications, you know, obviously, um, you know, stuff through the clinic, but spent a good amount of money on myself so I don't have to pay for it in the future with medications.

[00:57:41] And they're like, wow, that's crazy. And I'm like, how is that crazy? So to me, that's

[00:57:44] Carl Lanore: [00:57:44] not crazy. Right. And if you're sick. And you, you and you, all you worry about is having health care. Remember those of us who aren't burdening the system, the money we pay every month, and I pay a stupid amount of money for it, for healthcare, for Elisa and I, but we never [00:58:00] use it.

[00:58:00] So that means that I'm paying for somebody else who doesn't give a damn about their health, who's living a high risk lifestyle because they're fat and they're unhealthy, and they stay up all night and watch TV or play on their iPhones. I'm paying for their healthcare. I don't like that. I don't ask anybody to pay my mortgage or anything like that.

[00:58:20] I don't want to pay for somebody else's bad decisions. I don't.

[00:58:23] Ronnie Milo: [00:58:23] Right. Absolutely.

[00:58:24] Carl Lanore: [00:58:24] I agree. So get your shit together. This is the time to do it. So next time this, uh, next pandemic and there will be a next pandemic. Trust me and it will come from China. Why are liquor stores essential? This is a great question.

[00:58:37] This is a great question by Jeff. Why a liquor store is essential. That can't be helping right now. You're right. Why all liquor stores open? I mean, they closed gyms, but liquor stores are open. Yeah.

[00:58:51] Ronnie Milo: [00:58:51] They're making money. They're making money for the government.

[00:58:53] Carl Lanore: [00:58:53] Yeah, because there's a tax on. You're right. I didn't think about that.

[00:58:55] There's a tax on liquor.

[00:58:57] Ronnie Milo: [00:58:57] Absolutely right. They're going to keep that open and [00:59:00] like you said, they closed the gyms. The gyms are more preventative than actually liquor stores because now people are staying home all the time, drinking liquor low on their immune system. Now they're more susceptible to get the virus.

[00:59:11] Carl Lanore: [00:59:11] So a couple things. Aiden Ray points out. He says vitamin C is being used to prevent the cytokine storm that obliterates the lungs as covert 19 aggressively progressive, similar to university of East Virginia, dr Merkel's sepsis magic bullet. I actually did a show about the sepsis, a magic bullet, but here's something that actually prevents a cytokine storm even to a greater degree.

[00:59:36] And that is that, um, it's a sulfur based. Supplement, uh, MSM, methyl that, that, that works better than vitamin C. if you're worried about cytokine storm

[00:59:48] Ronnie Milo: [00:59:48] wind by increasing immune function, but I don't think it's going to be more of an antiviral.

[00:59:53] Carl Lanore: [00:59:53] Right? But, but if you're worried about the cytokine storm.

[00:59:56] Don't try to suppress the cytokine storm and [01:00:00] leave the thing that's causing it intact. Go to the root of what's causing the problem and kill it. And that's sad. Senescent cells. There'll be studies in this selection today on my website that showed the, the secretion of cytokine, uh, uh, uh, cytokines into Lukens from senescent cells.

[01:00:20] These are the source of these, these damn things, so let's get rid of them as well. So there you go. That's it for today. I'm done. You've got a

[01:00:33] Ronnie Milo: [01:00:33] great show.

[01:00:34] Carl Lanore: [01:00:34] Uh, thank you for listening today. Tomorrow we're going to do a show about a new enzyme that will help you digest your protein so that every gram of protein actually acts like three grams of protein.

[01:00:45] How about that? I mean

[01:00:47] Ronnie Milo: [01:00:47] on that one.

[01:00:48] Carl Lanore: [01:00:48] That'll be a good show. All right. Listen, thanks to everybody for watching today. I'm sorry, I was so. Moving so high speed and talking literally over myself, but I'm just excited about this information. I hope it gets out to the people. If [01:01:00] we start to focus on reducing senescent cell proliferation, we can not only control this virus, but we can cure people and that's the way it goes.

[01:01:10] I will see everybody tomorrow with more super Jaredo. Thanks Milo for being here and dr Andrew, thank you so much for being here, brother. We got to get together soon. Alright? See everybody later. .