The Pep Talk: Oxytocin: The Most Anabolic Peptide Dr. Elizabeth Yurth, MD

While people were still talking about oxytocin as the “love” peptide hormone that helps build bonds, improve mood, strengthen labor contractions during childbirth and help make breastfeeding easier, it was becoming evident to me that oxytocin was much more. From increasing a gut microbe that reversed aging in rats to making old muscle recover and heal like young muscle. Earlier this week on show 2610 we learned new information that oxytocin in the post-menopause model reverses osteoporosis! To add the final piece to this puzzle today we will discuss a study that points to all of the muscular gains experienced when using the strongest and harshest anabolic steroid in the world – Trenbolone – appears to be due to its ability to raise blood and tissue levels of oxytocin 50 fold! We will explore this and a few other effects of oxytocin that may make it one of the most important drugs for bodybuilding and performance enhancement in the world.

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Trenbolone and Oxytocin Study https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00226.2010

[3:22] Trenbolone’s anabolic effects are potentially from oxytocin.

• Perhaps oxytocin could offer some of the same benefits.

[6:30] Evolutionary perspective of oxytocin.

• Oxytocin is released whenever actions are performed to propagate the human species.
• Perhaps it could be extending the life of those that still contribute to propagation.
• Shifts mesenchymal stem cells from contributing to adipose tissues and into osteoblasts.
• Could reduce age related sarcopenia and osteopenia.

[11:50] Oxytocin and the heart.

• Oxytocin aids in myocardio contraction.
• Also has neuroprotective benefits in those with cognitive decline.

[16:00] Oxytocin is very anabolic, but it shows no cancer growing effects at fairly high doses.

[17:30] it has glucose partitioning effects.

• Lowers systemic insulin and pushes insulin into muscle cells.
• Has a vasodilatory effect.

[32:20] The anti cortisol effect of oxytocin.

• It is probably not a good idea to use it upon waking for this reason.
• Traumatic events also warrant a cortisol release.

[35:20] Dosing for sleep.

• Dosing is variable.
• Carl uses 20 iu before bed.

[41:30] Should it be cycled?

• Probably not. The half life is ~6 minutes, and the body’s production slows down as we age.

[50:00] Can oxytocin be used by itself?

[54:00] Oxytocin does not occur in food. IV vs. intra-nasal.

[55;30] the future of oxytocin research

• Post coitus?
• Human equivalent dosages?

[1:05:00] We can’t hide from Covid.

• Show 2714 in May: Carl states that we can’t wait the virus out.