Abstract (provisional)
Background
Dairy food is an important natural source of saturated and trans fatty acids in the human diet. This study evaluates the effect of dietary advice to change dairy food intake on plasma fatty acid levels known to be present in milk in healthy volunteers.
Methods
Twenty one samples of whole fat dairy milk were analyzed for fatty acids levels. Changes in levels of plasma phospholipid levels were evaluated in 180 healthy volunteers randomized to increase, not change or reduce dairy intake for one month. Fatty acids were measured by gas chromatography?mass spectrometry and levels are normalized to d-4 alanine.
Results
The long chain fatty acids palmitic (13.4%), stearic (16.7%) and myristic (18.9%) acid were most common saturated fats in milk. Four trans fatty acids constituted 3.7% of the total milk fat content. Increased dairy food intake by 3.0 (? 1.2) serves/ day for 1?month was associated with small increases in plasma levels of myristic (+0.05, 95% confidence level-0.08 to 0.13, p?=?0.07), pentadecanoic (+0.014, 95% confidence level -0.016 to 0.048, p?=?0.02) and margaric acid (+0.02, -0.03 to 0.05, p?=?0.03). There was no significant change in plasma levels of 4 saturated, 4 trans and 10 unsaturated fatty acids. Decreasing dairy food intake by 2.5 (? 1.2) serves per day was not associated with change in levels of any plasma fatty acid levels.
Conclusion
Dietary advice to change dairy food has a minor effect on plasma fatty acid levels.
Alex's Notes: Honestly I don't have much to say about this study. The authors begin within the context of the flawed lipid hypothesis, and dairy fat is mainly saturated and trans-fat. Of course the trans-fat from whole foods doesn't possess the same risks as industrially created trans-fats, and the lipid hypothesis has been ripped apart countless times.
