[00:00:00] ] I continue to be the one eye'd host at least for a short period of time longer my eye feels like it's getting better. I actually am able to see things through the cloudiness of it. We just lost oh there you are. Okay. Well movie right back up, dr. Page. Let's go ahead and bring him in here. Hold on a second.

[00:00:48] I just dropped this camera. I think or I'm going to just hold on one second. I'm going to move me over and try to bring you back up. And [00:01:00] let's see. Anyway, today is Friday. And that means that this is the pep talk with. Dr. Carl page my co-host. How you doing? Dr. Paige? Are doing quite well, thank you.

[00:01:14] We have you on the other side. We'll fix that after the break. Anyway, this is an interesting show because we're going to be talk. I got to stay back away from my Mike. I've been telling people are telling me I'm so I've come out too loud on Facebook. And I think it's because I'm just too close to the microphone.

[00:01:28] We're going to talk about a very interesting peptide and it's called copper peptide talk about it tell us what it is and and and and some of the information. GH K CU is that you know the name of it. It's really a tripeptide very small naturally occurring found in multiple tissue locations in the body really discovered roughly nine early 70s.

[00:01:55] It has a lot of regenerative skin particularly impact [00:02:00] Works locally, but really my concept of it is more like a copper buffer. You know delivering the important copper ions in places. It's needed for a lot of physiologic response reactions to inflammation or recovery or newer generation, but also has some play trophic effects as well in as more recent data on you know, actually gene expression modulation.

[00:02:24] You know more than just that local buffer for copper deposition. Now this peptide seems to have an affinity to Copper it what why do you think that is? Why did this peptide which it's a tripeptide? It is very small. Why does it seem to attract and attach the cop? You know, it's just the chemical structure of it with a copper ion.

[00:02:45] It's almost like it was literally designed to do that. You know, it's so it's naturally occurring it was not a synthetic peptide. So you know in Copper is very important in on multiple of metabolic processes in the body. It's a so, it's [00:03:00] its purpose in life. You know, it's essentially what is it?

[00:03:02] What is a Roku look like a raccoon? You know what I'm passionate about this stuff with me. So what does that mean to people who don't have enough copper because there is a lot of there's a lot of people who have copper deficiencies. In fact, I did a show probably eight years ago that linked certain types of cardiomyopathy to suboptimal levels of copper.

[00:03:26] It actually causes the muscle of the heart. To become weakened and striated and it develops a almost fibrous so we know there are people out there who don't have enough copper in their bodies what happens if they don't have enough? You know, it's one of those chemicals that are elements that needs to be in the right range.

[00:03:49] Okay, you can get too much copper and it can cause problems or you could not have enough copper and cause problems. So I think that's really where ghk see you comes into play on the local level with its [00:04:00] effect is that it's that buffer that that can provide that copper when it's needed or actually.

[00:04:06] Take up the copper if there's too much copper for things to work at an optimal level. So that's at least my brain where conceives it. Is that copper buffer. To really be able to keep this this local environment in Balance related to Copper metabolism so that you don't get inadequate levels or excess levels, you know, total body levels of copper can be overloaded for a lot of reasons or in you know, inadequate production of certain proteins genetically or the inadequacy of enough copper probably is going to be the most people on a dietary basis.

[00:04:40] And it pretty I was just telling patients Google what's got copper in it? You'll be it's a pretty well, but then there's an interesting phenomenon. I actually had this text messages between myself and dr. Seeds and I think I shared with you that I was suffering from Iron overload. But and or more people in the United States have way [00:05:00] too much iron.

[00:05:01] Then then don't have enough iron and iron displaces copper the more iron your body absorbs the more copper it displaces and you excrete so there's a probably a good possibility. That because we know that the literature shows that this naturally occurring tripeptide seems to like so many things diminish with age and it could be that our propensity to accumulate iron could be helping drive this diminishing levels of of this copper peptide.

[00:05:36] What do you think about that? You know, that's I think that's a great hypothesis. I don't know off the top of my head aware of the published literature that would support that but I think it makes a lot sense. But you know these elements do interact with each other in the body has a very complex mechanism to try to keep that in Balance if you've.

[00:05:55] Too much of an overload of iron which is very common in our [00:06:00] current least in the Western World. It does create copper metabolism abnormalities in directly. And in the majority of the patients LLC will have more too much iron is opposed to not enough iron. That's much more common. Yeah, and so this peptide seems to play a profound role on protecting liver cells.

[00:06:26] There there seems it. Actually there's some research out correct me if I'm wrong. I just gleaned this research. But is it there a study out there that shows that it's either protective or regenerative and maybe part of the reason the way the liver regenerates is because of this peptide. Yeah, that's definitely data available support that.

[00:06:44] You know what it is, but you know soft tissue skin or where most of the data is going to be it's been published but that may be more of a what's needed in the community in our what's in the most demand but you know the copper peptide and [00:07:00] copper metabolism is regenerative as far as causing a new blood vessel and growth and Recovery.

[00:07:06] Honors solder level for multiple tissues in the body, you know, it's not just a skin peptide alone, which is where most of the you know, non-medical data. We're going to see on it and we're a lot of the published areas. Yeah, because the Cosmetic industry is a hundred billion dollar industry and they seem to love this peptide again because.

[00:07:27] It's around right around 400 point something Dalton. So it's it's exactly at the threshold where it can get through the stratum corneum, but also because it seems to stimulate resynthesis of collagen and structural fibroblasts and skin that it is that a desirous to keep your skin from from getting wrinkles and sagging right?

[00:07:49] One minute. It's can tighten your skin reverse thinning of age skin, you know it kind of repairs that skin skin outside wall barrier it missed the [00:08:00] skin is firmer as more elasticity can be clear loss of some of the like brown spots with aging fine lines and wrinkles, really. List of positive things that are associated with application of it that are documented are pretty long list of all good things and since the you can theoretically get overloaded on copper with it and get copper overload, but that's hard to do and if you do notice some of the early symptoms of it just backing off the use of that it will resolve itself.

[00:08:30] Kurt Yaeger posted a question. I'm going to put it up here now because since we just talked about iron if you know what I'm not doing a good job. I'm half blind to cut me some slack. Okay, so he said is there ceruloplasmin interrelationship with iron to Cellular distribution? I don't know if he's asking this question about.

[00:08:52] This copper peptide because ceruloplasmin does have a relationship with iron absorption. We do know that and storage [00:09:00] and in fact, it may be a better Target for identifying. Tissue levels of iron in people, but I Kirk if you could post a little bit more. Are you asking this question in contrast to the role of this copper peptide and we'll wait for him to come back on that.

[00:09:18] So so let's talk a little bit about DNA. This peptide seems to have some sort of protective mechanism with DNA. Is that correct? There's some literature out there. There is someone at your throne that Neil, you know, DNA is vulnerable to you know, ionizing radiation is the big issue now, I'm not I don't know what I can explain to you in detail what the impact of the copper peptide is on protection of DNA, but.

[00:09:47] There is data available. So the mechanism of action that I can't really go into detail because I'm not aware of that. So you have anything on that I'd be glad if you throw it out there. Yeah. No, I really don't I again I just glanced at some of this stuff because it's [00:10:00] because this is a really interesting.

[00:10:01] You know what I'm starting to notice and I don't know if I'm right about this or you've noticed this as well, but it seems that these these smaller peptides these two three four five. You know even up to eight amino acid peptides they seem to have plea atrophic effects that the larger peptides even going up to growth hormone at a hundred ninety-one amino acids.

[00:10:25] They seem to have more specific narrowly focused affects how you noticing that absolutely look at this very small peptides. You'll see the little, you know, three four sequences in the larger peptide. Right. We'll be there in having, you know plain part of that sort of interesting. Yeah, they'll be in the larger pepper.

[00:10:48] I like to I like to refer to the amino acid sequences that we see as syntax because we know that peptides are [00:11:00] messages and like messages they have words and spaces. That tell the story and words to me are like your example here that you can look at some of these other peptides and you can see this peptide maybe two or three times at different points the same way you would see the word the or and stringing together a concept or an idea.

[00:11:22] So I like to refer to that as syntax. Are you saying that this peptide shows up as sent a lot as syntax in a lot of other more complex peptides? Yes, yes, and you know that's not true just for this one but several other smaller peptides but it is like a language and that language when you have a lot of words has much more specific meaning in when you have small pieces.

[00:11:45] It can have a much broader, you know be using a lot of different context essentially is what you're saying with the word syntax. Yeah. Yeah, and so do you not understand all this yet? But it is very fascinating. Oh, I know you can get into a huge Deep dive on it [00:12:00] reading a few if you want to spend it.

[00:12:01] Few weeks on it. Yeah. Well, we we leave that up to dr. Seeds. Yes what he does. He does all the heavy lifting the rest of us have gotten the rest of us look like Geniuses. Yeah, we downloaded a lot of it to me. So I certainly appreciate that. Yeah, so what about its ability to reverse the effects of aging on it says specific tissues a certain tissues.

[00:12:23] What kind of tissue is do we see that in besides skin, obviously. Sure, excuse the big Wonder but neurologic tissue cardio cardio vascular tissues. Really? Yeah. So those are probably the biggest ones, you know, the effect on nerve regeneration is particularly interesting because we have neuropathy like we talked about in a couple of talks.

[00:12:43] I'm particularly interested in that one myself that those are going to be more likely on a subcutaneous application. Unless you've got some really superficial peripheral neuropathies, you know, but especially on excellent route be where you have loss of the neuron, you know, I'm [00:13:00] interested in that and trying to say yes, you know, we demodulation and remodeling Remodeling and you're on you've got a better situation there, but actually getting a neuron to regenerate is so far.

[00:13:11] We've not been very good at that. So does this peptide effectively cross the blood-brain barrier? You know from a science standpoint. It should I can't quote you a study that says they've applied it topically or given Sub-Q and seen across into the central nervous system, but it's getting pretty close at the you know, Foreigner dolphins are it's, you know nerve and blood vessel regrowth have clearly been documented with it.

[00:13:40] I don't know if that is from Central Nervous tissue though. I don't have that data in front of me right now. You know, this is interesting because since it. Since it naturally occurs in humans and mammals, since it naturally occurs in humans, you would think that it probably does cross the blood-brain barrier again everyone.

[00:13:58] Yeah, it should [00:14:00] from a science standpoint. I just didn't want to quote it without having a data to back it up. No, no. No, I got it. Yeah bro, and then, you know this possibility has been found in other tissues, you know, maybe it's like a lot of things it's produced there but after an injury or trauma, it may not be able to make enough of it to called recovery.

[00:14:17] So. So if you were going to use this in your practice with someone who came in and had peripheral sensory neuropathy or even muscular activation Innovation neuropathies, you would give this to them systemically you'd like. You said Sub-Q. What kind of dosing would you look at? You know, the dosing always get confused with a new because I use units and everything for all this and you like.

[00:14:45] Yeah, I know. I'm home brew guy you're so you're what you're what you're doing is when you get it from the pharmacy, it's already it's already reconstituted at a certain. So so maybe a couple grams a day 1 [00:15:00] to 2 milligrams a day ceramic that. Would you would you do this all over the course of like twice a day or one shot in the morning one shot in the evening?

[00:15:11] Because the volume of what it would concentrate down to just you know, because when you get above half a ml so cute and that sometimes so it just depends on concentration of it is how you would split it up. At least off the top of my head it is systemic, but I would probably want to apply Sub-Q near where we had the neuron.

[00:15:32] Yeah get it because because I learned this years ago. So when you inject the peptide it starts to seek out receptors immediately. So naturally it's going to saturate The receptors. To the injection site first and then once they're satisfied it moves up the road and it's this kind of almost like, you know, a rhythmic transition outward.

[00:15:56] So you may as well even like with things like bpc [00:16:00] 157 if you're dealing with tennis elbow then injected as close to the side as you can get reasonably. Because it'll start to work faster. If nothing else, right? I mean if you're going for more of a systemic effect or up regulating growth hormone receptors are things you might as well do it in the abdomen vet.

[00:16:15] If you've got a targeted at nit incentivize for tendinitis. I usually do a plot BP one57 wall cloud would look at the ghk see if we trying to achieve, you know generation the same way from a peripheral neuropathic. Yeah, I want to take our first commercial break and when we come back, I want to talk briefly about something that's kind of exciting about this peptide and is that there was an early French?

[00:16:40] That showed that it actually regrew hair and when you talk about regrowing hair, there's a lot of guys, not you. I know you're happy that you don't have to worry happy. Yeah, I know but but there's a lot of guys out there including myself who would like to keep as much of our hair as possible as we go through life and this peptide may have some real magic to it.

[00:16:59] So [00:17:00] let's stay tuned. We'll be right back with more we're talking with. Dr. Carl page if you want to reach out to him, his website is. Medical transformation center.com we're getting people in the audience Who Loved dr. Paige feel free to reach out to him. We'll be right back with more of the pep talk.

[00:17:16] Welcome back to the pep talk with. Dr. Carl page and myself Carla know who continues to get too close to the microphone. I want to kiss it. That's my problem and I get too loud and dr. Seeds texted me. I've got it right here. And he said sure we can talk about it. So this fits nicely coming out of the break because I alluded to this that there seems to be a quality to this peptide that may regrow hair.

[00:17:43] Yes. There's a lot of already published data that was supported of that a lot of anecdotal data that's you know, small small groups that has not been published and then some pending study pending. How much data current are be in place with the doctor seeds with his [00:18:00] work on the hair regeneration using the GHQ GSK peptide along with a few other things to generate some quite remarkable hair regeneration and and the French study not only showed regrowth but it showed that grey hair went back to the original color and we know and we know that copper plays a role in pigmentation of the follicle.

[00:18:24] Correct, correct. I mean it just like it does in the natural world with leaves and things like that to generate colors and you know, so, you know, it's an anti-inflammatory locally, you know, it has some ability to block DHT, you know off reductase conversion and you know, those are already great things, but when it look at its angiogenic properties its ability to help with stem cell production in migration.

[00:18:50] You know all of the things you would need to cause recovery of local tissue and regeneration or a really augmented by the copper peptide. So [00:19:00] now that you mentioned about anti-inflammatory effects there looks like there is actually some research new research going on where they're looking at this copper peptide in place of corticosteroids.

[00:19:13] Now, we know that corticosteroid. While they reduce inflammation they do it at a pretty hefty price. They do it at degeneration of soft tissue weakening of soft tissue degeneration of muscle tissue catabolic effects on muscle tissue. They also can screw up electrolyte dramatically and partitioning of calcium and sodium and potassium that can lead to at.

[00:19:40] At least facial swelling and water retention at bat at worse changes in heart rhythm. So corticosteroids while you know, they're what we got and we need them sometimes and let's not forget. Most of them are delivered orally and their methylated which means that there's a lot of damage or potential damage to the [00:20:00] they like to call it hepatic stress.

[00:20:01] So you have to take a short period of time and all of a sudden here. We are, you know once again with the. That doesn't do any of those horrible things, but may actually do all the things that corticosteroids are known to do right left out diabetes and weight gain and all the other systems for the global systemic things attacking the school choice.

[00:20:22] Yes, they've sort of been magical in a certain way steroids, but they come like with it's like using a sledgehammer to you know, kill a fly. They just really obliterate so many other things and disrupt so much metabolism. So the copper peptides have quite a. A unique ability like a lot of peptides to sort of come in locally assess the situation and act where they need to and leave most other things untouched and and they can be used in combine later would be P 1 5 7 to help recovery from steroid local impacts and mustard has made and things like that, you know to.

[00:20:58] Allow that when you [00:21:00] get a big wall thinks I'm sure a lot of positions have seen this where you get that shot of steroids and someone from also when they come in two weeks later now, they've got a giant divot or a lot of muscle tissue donors. Yeah, yeah, it does give you a short-term effect, but it is it's a huge consequences Downstream.

[00:21:17] So, you know these Tech the peptides with a copper BBC one five seven can help recover from from that type of damage that's generated from traditional medical management of the senator and so is its anti-inflammatory effects that pronounce that it because corticosteroids they work very quickly person could walk into their doctor's office.

[00:21:40] And have a terrible case of chronic overuse in their elbow. The doctor gives him a cortisone shot. And by the time they walking out there like well and I should I have to step back most doctors include some sort of anesthetic. You know what numbing agent when they [00:22:00] inject it. They say it's so that they know that they're hitting the right spot, but that's really why people feel better immediately.

[00:22:06] But it's true that these corticosteroids are pretty fast acting at suppressing inflammation and pain would the do the copper peptides work that fast. It still has baby within hours, you know, that's you know, six eight twelve hours depends on the steward used and half-life of it in the potency of it and the volume you would use is to how soon you would get an impact from it, but you're right the most immediate thing with the stewards going to be the thing to make it kind of numb it up, right?

[00:22:32] But then your copper peptides, you know, I don't know about God information or data to give you that say that they're going to immediately replace that in clinical use but they've got a lot of potential and certainly there's a lot of work needs to be done in that area because the. The downsides of the long-term use of your local or systemic steroids are going to that way outweigh the benefits in a lot of cases in the Physicians administering those in the vast majority of cases are you know [00:23:00] getting informed consent on that and we sign some papers for they stick needles in you.

[00:23:04] It's going to make you feel better. But there's going to be some downsides to it or potential negatives. So yeah, you know, they're aware of that and it does dictate the amount in the volume using local steroid injections and how much you can use in a particular tendon, you know, if you just took who are the other night that they thought Blues Achilles, you know.

[00:23:22] Oh Kelly Duran. I hear that I hear about this story this story. I've heard over the years every time I've heard about someone getting a steroid injection in an elbow in a wrist in a muscle in the in the leg and literally like two weeks later blowing it blowing attendant just going to put it here and and one of the things I discovered and correct me if I'm wrong.

[00:23:50] Because I may be wrong but but chronic use of which there are a lot of people who have chronic pain and say they say, oh, you know can only get three cortisone shots a year for [00:24:00] cortisone shots a year, but by the end of the year the affected soft tissue the the tendon itself starts to develop what is known as tendinosis where this the tissue starts to unravel and become striated and more rigid where it's actually prone to breaking.

[00:24:20] Right. It's it'll create a section of the tendon at such a weak Link in the chain essentially in the whole tune itself. Is that the same it's going to stress fail and wherever that we've linked is essentially and you know, that that's known to happen with with, you know, large Timmons like a, you know, Achilles and things like that.

[00:24:40] They're not going to drop a big load of steroids into that because it's just takes too much load and it'll it's going to fail. You know if that happens so. Yeah, so this is another area of exploration for this copper peptide. Well, so so this copper peptide if it would it be wise to use this copper [00:25:00] peptide as a prophylactic as your aging to put into your regular because I use a lot of peptide prophylactically.

[00:25:07] I use PPC 157 post-workout all the time because I want to recover faster. I have now switched away from growth hormone, and I'm using 100 micrograms. Of ghr P6 and 100 micrograms of. Real CJC 1295 and always Frank frustrates me that I have to qualify quantify or qualify CJC 1295 has the drug Affinity complex.

[00:25:33] If it's not then it's just called growth hormone releasing hormone. But I use I use a hundred micrograms of each a couple times a day. And and so I'm using these things prophylactically if they're not therapeutic because I don't have a problem yet. Could I use the this copper peptide prophylactically you.

[00:25:52] From a recovery standpoint for from skin standpoint. Yes. I mean a lot of people will use it for Fine Lines [00:26:00] wrinkles age spots. You use it for a while get the skills the skimmer covers, then you can back off you do have to watch local overload. If you would I want to use it every day for months on end, but you can watch local effect and when things start to regenerate then you can decrease frequency and even use intermittent use on it.

[00:26:17] But from the skin standpoint absolutely from a body recovery standpoint, you know, it has data on it for use as an experience with it for use as a general recovery. And but the main things are going to be initially skin elasticity as and skin recoveries what we've got most of the data now here here recovery the hair the hair One Look regrowing hair or protecting hair from being lost in the first place is a multi-billion Dollar business.

[00:26:51] It's it goes from hair weaves and. And hair transplants to Federal FDA approved [00:27:00] shampoos and drugs and and so on. In fact, we just picked up a new sponsor keeps.com and they offer to Fantastic FDA-approved one is a shampoo at stupid low prices like this stuff. If you you try to get it locally and it's ridiculous, but it's like $10 a month with them.

[00:27:19] But but this is this is this is big bit like next to erectile dysfunction. I would get I would say that more men are worried about their hair than their erections and and you know, I would say it's probably bigger than that because if you don't have the confidence to really get out of the house and initiate contact.

[00:27:37] You don't need I don't need an erection. Exactly. Yeah, that's a really good point. But you know, but the reality is that if this really works and I can't wait for dr. C. So those of you who are members of ips already. We have a lot of Physicians who listen to this. You already will know about this because dr.

[00:27:59] Seeds is [00:28:00] preparing a lecture now about using this copper peptide to regrow hair and I'm sure he'll get to the bottom of it whether or not pigmentation comes back as well. But if this works this is going to be like forget about it. It's going to be huge because. Because instead of using drugs that block DHT which have other side effects or instead of using things that you know, you always after you put it on.

[00:28:29] You can't go near your children for an hour. This will be injected micro needle into the scalp and hair will start growing. Do you know what period of time they're looking at hair regrowth to start sprouting because I know the antigen there's phases of hair regrowth you have to wait for them to wake back up.

[00:28:46] You know, there's there's initiation of the protocol and then ongoing use but it's in the matter of weeks to months that you're going to you know, yeah, it's not like 10 years of application before you can see turn around [00:29:00] on. It's quite remarkable is the initial appointment a things. I've seen on it are quite remarkable forget about Bosley and all these companies that charge you tens of thousands of dollars to take care of the back of your neck and put it at the top of your head.

[00:29:14] If you could just inject the. And get the hair to start to regrow what guy wouldn't do that first. Well, you know, we're looking at it back at just how it peptides work and they work locally. They're signaling trickling molecules. They sort of I looking like buffers of life, you know, they normalize.

[00:29:32] The way life supposed to work in their local application when they were having their impact, so it's really remarkable how these little small peptide sequences are like the words of the language of Life. Essentially that makes sense when you understand what they are and how they were in kind of explains the ability to have a very potent effects with really negligible for the most part potential or even measured side.

[00:29:59] You know, I've looked [00:30:00] into this because I've said this once I said this one day unabashedly and then thought you know, I've got to go back and look but the reality is that I don't think there is any peptide we're using today and this includes growth hormone other than insulin other than insulin that there is a known lethal dose.

[00:30:22] I mean some of the biggest doses I mean HCG they give women 10,000 units in one so intramuscular shot to stimulate the correction of hormones that make them fertile. I mean. Okay, I've taken too much melanotan one time and it wasn't pretty because every every dark spot on my body literally turn black.

[00:30:49] It was like, oh my God, I just gave myself black cell carcinoma. You know what that's going to look. Yeah. Yeah, but but I mean those things I mean they yeah they make you nauseous and stuff like [00:31:00] that, but. They don't kill you these peptides by and large are fairly, you know easy to deal with if you take logical doses.

[00:31:10] Sure, and if you follow, you know, the available guidelines on dosing you're going to experience side effects the local site injection side effects may be some flushing with CJC at the a lot of people will get you know, every multiple injections. Don't get a fresh episode but it is making it does make you feel a little strange when we do it, but it's it goes away quickly.

[00:31:31] It doesn't have any positional and there are ones that particular with the growth hormone secreted Gods, you know, the super potent ones that are. Forever then, you know long-term over to use those comes along with all the known side effects of excess growth hormone use, but that's why things like CJ see if a being low potency and not saturating the receptor or much better alternative than we used to have.

[00:31:53] So the availability of these modified peptides tweaking and down to the. Dos that [00:32:00] works, but doesn't have side effects of any measurable amount if used appropriately is just wonderful. So if I wanted to I'm listen, I'm thinking of this if I wanted to add. This copper peptide to my morning regimen of peptides as a prophylactic because I'm thinking, you know, I'll just inject it it'll work on my skin.

[00:32:23] It'll work on my liver. It'll work on other tissue it'll work on inflammation. I'll just inject it if I wanted to take that as a prophylactic. I had no real signs of anything that I was trying to reverse one milligram a day you think. Yeah, but I'm going to probably pulse it just because of the potential for theoretically copper excess over time because you don't know what your environmental exposures going to be.

[00:32:49] You know how well do you clear copper, you know, do you have problems with ceruloplasmin that you don't normally wear out of you know copper metabolism or copper clearance defects. So, I don't know [00:33:00] what I would just start randomly on patient with a daily dose ongoing you would I would likely pulse it if it were going to use it in that manner and you would also want to monitor, you know, what copper in a system, you know Repsol copper ore.

[00:33:14] No serum coppers just to see if the patient had an overload and also the same time work exact metabolism because there is an interplay there as well as with iron. And why do you say pulse it? What would you do? Would you use it every third day something like that pulse or less likely to get you into a problem where it made me play?

[00:33:34] You know three or four weeks on couple months off, you know, one of those type of things you lose to you know, that might be at the Safeway that you could use it, but it certainly on going to use continuously. I don't know that I would recommend that. Okay. I want to take one last commercial break and when we come back, I want to I want to touch on the the DNA protective effects because there is some literature out there and you may not have seen it so we can't talk about it.

[00:33:58] We can't but there is some [00:34:00] literature out there that shows that this may protect against certain types of. I've Cancers and so we'll pick that up on the other side we're talking with. Dr. Carl pay just as the pep talk stay tuned. We'll be right back.

[00:34:14] I sound like Lou Costello when they speed up my voice in those spots. There's a lot that I had to say and I had to say it in a short period of time so they had to condense everything. I swear. I sound I'm listening eyes. Hey Abbott, I sound like the Costello. So anyway. Let's talk a little bit about cancer.

[00:34:32] Do are you aware of some of the research on on this peptide and cancer. Yeah, there's probably stay down there that I have reviewed some of that, you know, it's relatively recent to you know, in 2010-2014 Ryan couple of other studies that are out on particularly metastatic colon cancer and you know changing a gene expression signature to you know, You know help with that [00:35:00] and work on multiple different play Tropic Pathways to sort of Rio on the gene expression signature back to not being cancer-related has stones with skin cells and recovery from fiberglass from ultraviolet radiation damage.

[00:35:15] Wow. Yeah, you know, which is. You know resetting the a pop Tariq mechanism of a cell might become damaged to go to let it return back to its natural and that's and that's from the MP inflammatory because we know things like ginger and curcumin they help to re-establish that a pop tonic landscape by suppressing inflammation, right and, you know allowing the body to go ahead and deal with that potentially.

[00:35:41] Disrupted Keno cancer cell but also has been shown to inhibit neuroblastoma cells and histiocytic Lymphoma cells, you know all the way back to 1983 and some published data with. Pauling Institute regarding ghk [00:36:00] see you and combinations of vitamin C. It would work on realigning that expression of cancer cells in up regulating genes that would help the body recover from cancer or have this General anti-cancer properties in general.

[00:36:17] That's pretty exciting. That is so so if I were to use this, let's say I'm vain and I'm not because otherwise I would have done something about all these this this brow here. But let's say I want skin quality would I follow that pulsed approach and just use a milligram, maybe every third day and just give myself some time and what I see changes to my skin you think if I used a systemically as opposed to topically in a cosmetic deliver.

[00:36:44] You know in theory you would if you had particular areas that you wanted kind of like to be PC and tendinosis or tendinitis are probably would apply topically to specific areas particularly, you know, fine lines and wrinkles around the eyes and things like that. I would want to use a topical solution [00:37:00] in those areas until us all some effect and then back off and of course with the hair regrowth scenario, there you go and want to apply locally to where you want the hair to grow if you're going but in theory but in theory, yeah, you'd want to apply it locally.

[00:37:14] Right, so you could you'd want to really establish its effects in that tissue because we know that scalp tissue has impaired blood flow also as we age but but but in theory if you were using it long enough at let's say once every third day for years, you might actually start to see some hair regrowth just on its own, you know, if you're correcting the cellular processes, you know about systemic use that sort of led to.

[00:37:42] Hair loss in the first place then certainly would be a part of a general recovery regimen for hair, you know, at least in theoretical standpoint. I don't think there's any colors data on it feels like that right now though, right? So eight in Ray has a good question. He says is zinc supplementation recommended [00:38:00] when you are pulsing and and this is a really good question because.

[00:38:04] While we're talking about this copper peptide. It's really the approach the amino acids that create the magic because this acts different than just regular cop. But it's not it was that sort of buffering in the cellular the loo or intercessor malouda copper adding that we needed to pulling out when you don't eat it need it and then the multiple clear trophic gene expression and down regulation affects that the peptide itself.

[00:38:33] So it's it carries copper around and delivers it where it's needed and pulls it out when it's not needed but the peptide itself has its own impact outside of just the copper metabolism. In fact now as far as zinc supplementation, you know, that's more looking at systemic levels of zinc versus copper, you know, if you're overloaded on copper you have to use zinc to get copper levels to come down.

[00:38:56] Naturally. It will balance that out in knows [00:39:00] how so many. You know the balance of copper zinc has so many impacts on multiple metabolic pathways and mood and neurotransmitter metabolism. So many people are zinc deficient, you know, when they are measured and the it's a balance of copper zinc so you can't give zook long term without making sure you're monitoring because they hang on interesting.

[00:39:20] Yeah, so that that's a good point. So in summary. The local effects of it are much more pronounced. Obviously. If you do want to change the quality of your skin, you probably want to get a cosmetic that has it in it. But if you want to just use it prophylactically to see how it can improve the quality of your complete functionality than you would use it.

[00:39:47] You would use it systemically if you're a doctor listening to the show all your a patient who would like your doctor. To have access to this stuff then what you need to [00:40:00] do is number one. Tell your doctor about the international peptide Society because they should join because they will be trained to prescribe and use these peptides with their patients.

[00:40:13] But then you also have to know where to get it. And the reality is that the place to get these peptides is at tailor-made ta ILO are made Pharmacy compounding pharmacy and. Kentucky I've been out there they have amino acid sequencers. They don't use recombinant technology to produce any of their peptides the quality the purity of their peptides is unparalleled.

[00:40:39] And so you dot your doctor can then prescribe for you and have your prescription filled so you can take advantage of these types of things. Remember those peptides you kind of have the same issues you do sometimes with the non analyzed research-grade peptides. You can get [00:41:00] prescription topical copper creams and phones for application, you know through Taylor Bank Pharmacy, and that's the ones that I use with patients because they're you know where with the non-prescription level there's always the issues of Purity and you know degradation of the product and Storage.

[00:41:17] So you want to treat them just like any of your other small amino acid sequences that they once you mix them with a thousand other things in a topical cosmetic solution. You don't really have a lot of data on how well it's going to work. It may work great. It may not you know, some of them have an impact that you can get prescription grade compounded topical copper peptides for skin care.

[00:41:37] I want to know is there anything else you want to talk about about this copper peptide? I mean the most exciting thing to me is the hair regrowth and possibly I mean that is like exciting my patients actually because we're going. Be introducing that for them, but that personally I'm totally fine with lack of hair on my head.

[00:41:53] It's no I know you and you look good with it. You know you get that Kojak kind of thing going on, you know, but [00:42:00] but you know II have a really bad mug and I can't even imagine if I had a dome on top to it. Really I'd be a scary guy to look at so I'm going to try to keep my hair and I'm hoping that copper peptide works for me.

[00:42:13] I want to I want to talk about something else, you know, just kind of a day in the life, so. Three weeks ago. I scratched my cornea being the thick-headed Italian that I am I insisted on continuing to wear my contact lens which led to an infection and now I have an ulcer on my cornea. And while the also will reverse I stand to have an aberration in my cornea a scar if there's a scar in the cornea.

[00:42:39] It's going to look like a little wavy or a little dull spot in my field of vision. And obviously, I don't want that. I don't want that at all. So I started digging around and they've got me on a bunch of different some nasty antibiotics doc. I'm taking I'm taking a topical [00:43:00] vancomycin and Toba myosin and they make me dizzy because they getting into my brain and they give me all those same symptoms that they give people who take large intravenous Doses.

[00:43:12] And so. I went to the doctor today and I I'm getting a prescription for bpc 157 because there is great research out there that shows that bpc 157 when used in an eye drop can actually eliminate the defects seen in healing of the cornea in other words in English. No, scar no blurred vision and I'm like, I'm on this I want to get this now and so, you know people don't understand these peptides are amazing amazing things and they are not just injectable or rub on your skin.

[00:43:52] Like I'm gonna leverage bpc 157 to make sure I don't have a scar on my cornea think of [00:44:00] that you should and yes, absolutely. It was like great day on that. It's if you look at the pictures of it, which if you just. PubMed search it you'd be able to find those they are, you know, if you PubMed, you know PPC one57 corneal ulcers yet.

[00:44:15] There's human and animal data on that. That's very strong in quite compelling. We look at the at the you know, control versus treated group. And in that if I had a corneal ulcer, I would be dropping it in my eye. But okay, so now here's where. Not so smart call comes in right so I did I did but here's the problem.

[00:44:35] I took my bpc 157 and I reconstituted it with just sterile.  It was water for injection. Well, it's not buffered and and and peptides tend to be acidic. Why because they're made of what amino acids keyword acids. So when I drop that stuff in without having a buffered isotonic. It burns the heck out of my [00:45:00] eye.

[00:45:00] That is not good. That's not helping my cause sure and you've also got an open wound with an ulcer there to on it as well. So any mistake Solution on that's going to be uncomfortable and I think your eye doctors would want to make sure you were using a sterile solution since they're trying to make sure no bacteria are growing in the air and that's important because it infection on top of them all services you may have worse than just a bird.

[00:45:24] Section of your visual field. Right? Right. I was told that if this infection got in now keep in mind the infection is gone, but I was told that if this infection actually breached a cornea that I would end up losing the I yeah, and so this is now I'm not playing around here. I'm serious, you know, but interestingly enough guess who has I dropped form of bpc 157 in a buffered isotonic vehicle tailor-made.

[00:45:52] Just got to ask, you know, a lot of times even if they don't have stuff they can get it for you. Well, they can and [00:46:00] that's how I start I said, hey, can you guys compound and he was like, no. We already have it. It's like awesome. Yeah, I'm telling you peptides are just magic people need to stop paying attention to what's happening in peptide science because these are things that fix problems and don't just cover them up.

[00:46:22] And make you think that they're not still happening and doctors need to get with IPS and join. They need to get trained. They need to start giving their patients access to this. This is this is the bleeding edge of the future of medicine right now and and patients deserve access to it. So you doctors out there you need to get on board.

[00:46:42] And get with IPS and reach out the TaylorMade Pharmacy and start practicing the kind of medicine that you went to medical school to practice. You didn't go to medical school to practice giving people statin drugs and blood pressure medicines and know you went to medical school cause you wanted to [00:47:00] help people and how do you help them?

[00:47:02] You fix them. You don't cover up you don't take the battery out of the smoke detector and act like the fire is gone. You put the fire out. That's why the doctors became doctors and peptides hold the answer to allow you to practice medicine the way you really want to practice medicine the beginning is that an overstatement because I know your journey, you know, I it's rejuvenated me on a personal level, but it's also rejuvenated, you know with the other things.

[00:47:30] I've done that peptides are a huge part of what I do now from a practical standpoint. It's so nice to have. Save tools that actually resolve problems as opposed to just block or dampen symptoms, you know, so is the anti-aging regenerative effect of a lot of these peptides. There's you know people with chronic autoimmune illnesses cognitive decline, you know skin hair issues, you know, it's a.

[00:47:55] You know covers multiple areas because they literally artist the most [00:48:00] part analogs or just direct natural substances that might have been tweaked for get a little more duration of effect in the body that they are so clean and they have their profound effects at the local and systemic level. Well, I had to all we've got today.

[00:48:15] This has been another episode of the pep talk will we do this every other week if you have questions for dr. Page email them? To on-air at superhuman radio dotnet and if you would like to reach out to dr. Page to see about becoming a patient you can a lot of people have to understand something you can be a patient.

[00:48:36] Even if you don't live in the state you do have to visit dr. Page one time in person here in Louisville. If you come here take me to lunch and then once you get home, you can do the rest of it through telemedicine Skype visits and everything else go to the website. Transformation center.com to learn more and if you have questions you have topics you want us to cover that a peptide in nature.

[00:48:59] Send me an [00:49:00] email at on are at superhuman radio dotnet. I know we got a question this morning about the pep talk I will send that on to dr. Page and have him address it in another show. Okay, dr. Page. Thanks a lot for being here brother. Thank you. We'll see you later on. We'll see everybody Monday.

[00:49:18] It's the weekend. I'm gone. See you [00:50:00] then.