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Transcript to SHR # 2374 :: The Pep Talk: PT-141 (Bremelanotide) Explored

[00:00:00] [00:00:00] Carl Lanore: [00:00:00] welcome back to another episode of superhuman radio on. My audio is way too low test 1 2 3 4 5 that's getting better. And today is an important show. I've been talking about the show all week because this is a return of the pep talk which many of you love this show. I can't believe how many other podcasters are listening to the pep talk now and messaging me about using peptides like LL 3 7 to rid their bodies of sibo.

[00:00:25] It's quite flattering actually anyway, Today's discussion is going to be about a peptide called PT 141 otherwise known as bream Leno tide and we're doing this because recently our June 21st the FDA approved the use of a drug called vile EC to treat women with hypoactive sexual disorder, I guess desire disorder, right?

[00:00:52] Okay, and this is really the first big step. That anyone has taken in the area [00:01:00] of working with women with some sexual dysfunction. I mean guys have Viagra Cialis and all this other stuff and porn of obviously and so so, you know women have been standing in the back going, you know, what about us, you know, we still want to be active sexually but there's something not working for us anymore.

[00:01:18] And so the FDA and if Divine wisdom has approved this and so today my guest is. Dr. Elizabeth were Earth. I'm sorry. How you doing? Dr. You Earth? I'm

[00:01:29] Dr. Elizabeth Yurth, MD: [00:01:29] great Carl. Thanks for having

[00:01:30] Carl Lanore: [00:01:30] me. Thank you for being here too. And so you are a member of the international peptide Society an organization that I've promoted since its Inception on this show that works hard to teach Physicians how to integrate peptides into their practice as a form of therapy.

[00:01:51] Dr. Elizabeth Yurth, MD: [00:01:51] That's right. I'm on the faculty of international peptide society. And we really have been trying to bring peptides into a much more [00:02:00] legitimate sort of Forefront from where they have been where they've been really widely used and kind of the bodybuilder or maybe performance athletes, but bring them into more medically manage settings.

[00:02:09] Yeah,

[00:02:10] Carl Lanore: [00:02:10] so it's funny. I for years. I spent decades on the bodybuilding and strength websites and forums and my screen name was try scepter. But my My Little by line was 250-pound with star rat because most of us experiment on ourselves and a lot of the information that we discovered ended up triggering research.

[00:02:34] So you're right it out of the Shadows so to speak into the. In Stream So talk about yourself first before we get started because I find it's very fascinating to people who are have moved towards longevity medicine all come from areas of medicine where they have to put people back together if they're broken.

[00:02:53] He have you noticed that.

[00:02:55] Dr. Elizabeth Yurth, MD: [00:02:55] Yeah, I think I think too. I think true friends. I think Physicians often times come to this [00:03:00] either from a desire for themselves for overall health or frustration from treating patients and really not getting where we want to go. My background actually is an Orthopedics and I've worked with athletes for 30 years.

[00:03:15] And sort of became frustrated with the athlete that we've sort of put back together, but they never really got better and then something else would fall apart and particularly as they got older. It was really just well you're getting older you're really never going to be able to do what you did before and so about 15 years ago.

[00:03:30] Now, I went back and retrained in functional medicine and regenerative medicine. And I still have an orthopedic practice, but I also have a clinic called Boda Longevity Institute where we do more performance medicine. So now we work with people to try and really just get them what we call optimized we try and get them to a state of kind of you know, superhuman we try and get people as as healthy as they can be doing everything they could do when they were in their 20s at a very high level and keep them there, hopefully [00:04:00] until.

[00:04:00] It's a hundred twenty

[00:04:02] Carl Lanore: [00:04:02] and that's something very unique to our generation. I say My Generation because I'm 61 years old, but you know, we're not welcome. You know, my father was willing to grow old. He was willing to sit back and take it slow. But our generation is like no we don't want to and we don't believe we need to and quite frankly a lot of it comes from the fact that.

[00:04:23] In the 60s we were told pot was going to kill us LSD was going to give us, you know trips we were going to trip and we're going to have a future trips because I mean I'm still waiting for that one. You know, I would I would invite it because I've been micro dosing LSD for a while now. It's like hey I can get a free trip for free now, but you know, it's like we were told all these lies about how bad these things were and we all survived and were like wait a minute.

[00:04:47] Maybe there's ways for us to leverage science. And make it work for us to live longer and be able to stay fully engaged in life longer.

[00:04:59] Dr. Elizabeth Yurth, MD: [00:04:59] Right [00:05:00] exactly. I think, you know, you are close to the same age. And I think that we've watched her parents sort. He's not so well either from a mental perspective or physical proof its perspective.

[00:05:08] My my dad's 90 and my mom's 95. My dad was climbing 14 years until I was 85, but after that it was pretty much a downhill Decline and you know you and I don't want to have that downhaul decline really ever in our hope is that we can go to a you know to our Graves still hiking 14 years and doing everything we want to do and and I think that that certainly is feasible.

[00:05:28] I really do but it takes work and it takes not only the right exercise and. Also be able to do all these things you're talking about.

[00:05:36] Carl Lanore: [00:05:36] Well, it also pay, you know, I don't I don't like the word biohacking. I actually like the word bio hijacking because I

[00:05:44] Dr. Elizabeth Yurth, MD: [00:05:44] like that.

[00:05:45] Carl Lanore: [00:05:45] Yeah because you know bio hijacking is really what it takes today.

[00:05:48] It takes heroic methods of using science. In ways that maybe it was never designed to be used but now we know like like rap a [00:06:00] myosin was never designed to help reverse senescent cells to quiescent cells. It was designed to create a cure cancer and being anti-rejection drug, but now it's finding its way into the anti-aging and so I kind of like to call it by a hijacking we use peptides we use hormones to literally hijacker body and go.

[00:06:17] No, you're not done yet. You're still young and we're going to we're going to make you keep operating. What do you think of that snake?

[00:06:24] Dr. Elizabeth Yurth, MD: [00:06:24] I love that. I mean, you know, we we work along with the bio hacker group and kind of consider ourselves biohackers, but you're right. I kind of like the bio hijacking.

[00:06:32] That's a great terminology for it because you're exactly right. We really are taking everything that was program. And now put it on a whole different route from where it was going. And so that whole hijacking it to some different destination than where its ultimate destination was makes a lot of sense in your ultimate destination is a slow spiral to death, right?

[00:06:52] So can biohack that hack that that pathway and maybe make yourself age more slowly. Yeah, but can we actually now [00:07:00] divert that pathway? So we actually have a more superhuman Trend that everything

[00:07:05] Carl Lanore: [00:07:05] we take we take the gun out we go. No, we are not going to the Grave. We're going somewhere else. Well Landing somewhere else and

[00:07:13] Dr. Elizabeth Yurth, MD: [00:07:13] then he be smarter more compassionate more energetic than we could ever have been Even in our younger day.

[00:07:20] So I think that's a really Advanced really cool way of thinking about hijack this whole life to a whole different different place than where it was ever had. Yeah.

[00:07:27] Carl Lanore: [00:07:27] So now let's talk about PT 141 bream Leno tied or now the legal drug name for it is vitally see I explain what it is. This is a peptide how many amino acids?

[00:07:39] Dr. Elizabeth Yurth, MD: [00:07:39] He said that's a 10 amino acid peptide. So it's a relatively small peptides for probably a lot of your listeners are familiar with peptides. The peptides are

[00:07:49] Carl Lanore: [00:07:49] oh, yeah.

[00:07:52] Dr. Elizabeth Yurth, MD: [00:07:52] Yeah, we always explain them to people they're basically shorter than proteins there. So they're 50 less than 50 amino acids. This is a relatively small [00:08:00] amino acid or peptide chain, but very potent one.

[00:08:04] Carl Lanore: [00:08:04] And it was it was discovered because am so just kind of create some backstory ASU develop Milano 10 one of my line. I'll tend to in hopes of developing a peptide that could help create a prophylactic tan if you will before fair-skinned people went out into the sun to minimize the chances of skin cancers.

[00:08:26] And one of the probably unexpected but very desirable side effects of melanotan to was that when you took the requisite, you know, 200 microgram shot it gave you a rise in libido. That was unignorable, right?

[00:08:44] Dr. Elizabeth Yurth, MD: [00:08:44] Right, right. That was one of the problems with it really quite frankly people were having the sustained directions or you know, they were they were getting the benefit of the dark skin, but they couldn't go out anywhere because they would have such a increase sex drive that they really couldn't go out in public.

[00:08:59] So it'll [00:09:00] actually a problem when it first came out and you and I both use I use melanotan when it first came out. We used to get it as a nasal spray from a European site, you know, 15 years ago, and it was great. It went and your skin. But it does it didn't have that side effect for shouldn't be especially for men that they would have such an increased sexual desire.

[00:09:17] They'd be in the gym just you know not able to work out

[00:09:20] Carl Lanore: [00:09:20] right? So so what happens is a group of scientists said, hey, let's find the amino acid sequence is responsible just for the increase in libido. Let's extract that. So it doesn't have the tanning effect and just focus on that. That's how that's how a PT 141 came around.

[00:09:41] Dr. Elizabeth Yurth, MD: [00:09:41] Right. So basically said let's yeah, so they separate it out into the different. So there's all these different melanocytes stimulating hormones. And I think one thing that just before we kind of move on as whenever we say this this melanocytes two million hormone people always get confused at least my patients do with with

[00:09:59] [00:10:00] Carl Lanore: [00:09:59] melatonin.

[00:10:00] Yeah. I

[00:10:01] Dr. Elizabeth Yurth, MD: [00:10:01] know we different. So melatonin is what you take to help you sleep and this is a completely even though they sound a little bit similar. The melanocytes pathway is not the Melatonin pathway. They have nothing to do with each other. So just to kind of get that off the table initially simply because I get that confusion a lot from my patients.

[00:10:20] But what they did find is there's all these different pieces of melanocytes you might hormones in different parts of the melanocytes the line of court and system and if they could isolate these different parts, they could use them for different purposes. And so now we can separate out. Okay. This now just makes you 10 maybe a few other facts or this piece of it just helps with libido, which is where now beliefs by Lee CPT 141 came from

[00:10:47] Carl Lanore: [00:10:47] and I've talked on with the show.

[00:10:49] My list is no for probably the past seven or eight years now predicting that all all of the purported benefits of vitamin D. [00:11:00] That that are extrapolated from large populations and then taken into research centers and don't play out the way we thought they would like its effect on mood its effect on atheros chronic plaque its effect on.

[00:11:16] Several different things are actually really because of the Milano court and system but a lot of court system is not getting the the the credit for it because no one's paying attention to it. And really the Milano court and system is an amazing. I mean, it's probably one of the most complex widespread as far as effects on the body systems that we have.

[00:11:40] Would you agree with that statement?

[00:11:42] Dr. Elizabeth Yurth, MD: [00:11:42] Yeah, it really is. I mean and if you look at all the different pieces, it's going to help it will affect immune system. It is it works with mood appetite suppression and acceleration sexy. So libido sex drive erection quality [00:12:00] energy levels. Skin tone so you're right.

[00:12:03] It's really affecting a huge Spectrum. I mean interestingly the whole using in for instance and people who have been Gene disorders and things like that because it has such a big pathway in terms of our feeding behaviors so it can be used really for weight loss as well. But it's also really critical in an immune regulation.

[00:12:24] So for immune health and you're right, that's probably where being in the sun. Versus just taking your vitamin. I

[00:12:30] Carl Lanore: [00:12:30] know we're all blaming on vitamin D and it's not vitamin D at all. And in fact I talk about this all the time, you know, I look at everything from evolutionary perspective. Why would this happen what benefits would it serve us and I've talked about on the show and other people shows.

[00:12:45] I've been interviewed on and I've said, you know, Anything that affects libido is important to pay attention to if you do something and it makes your libido go away. It's bad for you because we only have one job on this planet. That's the procreate. That's it. That's like every [00:13:00] other species out there.

[00:13:01] We need to keep the species growing anything that increases libido. Pay attention to it. It's good for you. And that's what the other thing. You know, when you go to the beach go on vacation with your partner your wife your husband you lay in the sun. You want to make love all the time. That's because the sun's good for you that pay attention to that.

[00:13:21] Dr. Elizabeth Yurth, MD: [00:13:21] Yeah, that's interesting as a really good way of looking at because you're right really are one purpose here on Earth is you know from a from a survival perspective is to have babies is to reproduce and so you're right, you know, everything should be driven to sex drive and if Sex Drive is reduced like a lot of medications do right and you know

[00:13:39] Carl Lanore: [00:13:39] starvation famine right when you go when we have famine the the body goes you can't even get enough calories for you.

[00:13:46] Never mind a baby. It turns off the reproductive system women stop. She's waiting, you know men lose their libido.

[00:13:52] Dr. Elizabeth Yurth, MD: [00:13:52] Right or stress which is probably the most prominent one in our world today. Right? It's everybody's completely dressed. So nobody has sex drive. It's really just [00:14:00] you know, and that's contributing to to aging and cancer and all the other disorders.

[00:14:05] So you write the the effects of anything that is increasing libido or probably in general, you know beneficial not obviously you can go overboard on that go to the other end of it.

[00:14:17] Carl Lanore: [00:14:17] But

[00:14:17] Dr. Elizabeth Yurth, MD: [00:14:17] yeah. Yeah and the right son is. The downside of said obviously is skin cancer. And so there's that piece of of what is the final line there?

[00:14:27] Well,

[00:14:28] Carl Lanore: [00:14:28] I so I've done a show on that skin cancer is the result of your diet not sun. The sun isn't is it an unsuspecting culprit in the process? It doesn't want to do it. If you eat the right Foods, they're protective against skin cancer. We know that everything we eat makes it into the Skin So if you're eating cat carotenoids and astaxanthin and all these things vitamin A real vitamin A retinol retinol casted we know that that actually protects.

[00:14:55] If you're eating the wrong foods that when exposed to sunlight [00:15:00] create carcinogens, then you're going to get skin cancer so we can really reduce skin cancer down to diet. It's like at the analogy I use on the show is like matches can start a house fire, but that doesn't mean that matches of the reason that there's house fires.

[00:15:14] You know what? I mean? They're just that they're an unwilling unwilling participant if you will

[00:15:18] Dr. Elizabeth Yurth, MD: [00:15:18] John there's all these protective things that you can do, you know short of covering yourself in sunblock, which is obviously blocking a lot of the beneficial effects of the Sun. There's a lot of things you can do internally from a dietary perspective that we know will help protect you and me.

[00:15:31] Carl Lanore: [00:15:31] Yeah,

[00:15:31] Dr. Elizabeth Yurth, MD: [00:15:31] I'm pretty dark skin in general, but I'm out in the sun a lot and you know, and I you know, I've probably low likelihood of getting skin cancer because of all the other things that I'm doing, right? So we write as health in general all falls into we have to look internally at the supplements were taking the food we're eating and that's going to be the Mainstay of protecting us if son was horribly bad for us our species wouldn't have.

[00:15:55] Carl Lanore: [00:15:55] But be here we went if son was hardly bad for us. Dr. Your Earth you and I wouldn't be [00:16:00] doing this show we wouldn't have an internet. There'd be no Facebook because we would we would have been gone a long time ago. So back on Haiti 141. So this peptide is injected, correct? They tried nasal, but didn't the nasal version cause worse side effects with raising blood pressure and stuff like that.

[00:16:17] Dr. Elizabeth Yurth, MD: [00:16:17] Read more episodes of hypertension with the nasal spray knows probably did you add the dough sit quite a bit higher to really get an effect. So the upside of the using it subcutaneously is you can use a much smaller dose now, I don't know about you, but when we used to use use. The latter courtin The Lads had we used as a nasal spray Works actually very well as a nasal spray, but for just handing the skin or darkening the skin you didn't need as much as you do it for dosing for the libido, right?

[00:16:44] So as you go high enough to get Improvement in libido where you would start to see as hypertension so became you know, they actually try to get it approved years ago for treating libido for that purpose and they couldn't because of that side effect. So finding that when we lower the dose using it's a few [00:17:00] tediously that that effect was.

[00:17:01] The ball made it now FDA acceptable drug

[00:17:06] Carl Lanore: [00:17:06] and the FDA has approved this for premenopausal women and I got that wrong. I thought it was postmenopausal women because those are the women that usually lose their libido, but it's just prenup right now. It's only approved for premenopausal women, correct,

[00:17:18] Dr. Elizabeth Yurth, MD: [00:17:18] right, which is interesting, right?

[00:17:19] You know, I read that I was like, well, I don't have nearly as many premenopausal women in my practice. There are some. I would love to beat. Oh, my biggest problem is, you know, the disconnect and couples where the man has will be. No still the woman has no libido and you know, it's a huge detriment to marriage and everything else.

[00:17:36] And so when I read this drug was approved only for premenopausal women. I was like, well that doesn't even make sense. I think the the reason is because if you take the typical postmenopausal woman out of the people would our domain who are using a lot of things most of them have no hormones. They have no estrogen they have no testosterone.

[00:17:55] If you are really no hormones at all, your progesterone testosterone estrogen are [00:18:00] all really important for sex drive. It's not we sort of testosterone gets all the credit. You can give a woman tons of testosterone and if they have no estrogen right, they're not they're not going to have any sex drive.

[00:18:11] And so if you have a female who has zero hormones. You're not going to get the fact by throwing a bunch of PT 141 at them. And so I think as you know, this is not something that you can just sort of. Oh, let's just use this you have to look at all the pieces. And so if you look at a postmenopausal women.

[00:18:28] First thing you need to do is make sure their hormones are right and a good and then you can add this on to get the effect. I think it's very beneficial drug for eyes metabolic. I want

[00:18:37] Carl Lanore: [00:18:37] to I want to clarify something to as long as we're on this topic. So Way Way Back years and years ago the consensus was that if a woman was a mentor react for one year it was too late to get on HRT, but that's changed hasn't it?

[00:18:52] We're starting to see a more of a well. You know, let's look at the whole patient before we just say a year is. Window

[00:18:59] Dr. Elizabeth Yurth, MD: [00:18:59] know [00:19:00] exactly true and we always get that question from our patients. Where is it? Well, I'm whatever I did this too late for me to start these and we realized determine that it probably doesn't exist it too late to start

[00:19:11] Carl Lanore: [00:19:11] certainly.

[00:19:12] Dr. Elizabeth Yurth, MD: [00:19:12] If you can't we do know that there was an issue say that just came out from cardiovascular benefit that starting women even before they became a mentor Rick so there, you know, actually a premenopausal state had the best cardiac protective of right Simon. We do know that starting earlier is probably better there doesn't appear to be an age where you're not going to have some benefit and we have women who start Who start HRT in their 70s and you have improve bone density and sex drive and they look better and they feel better.

[00:19:41] And so I don't think there is a too late age for starting to try and repair your body.

[00:19:46] Carl Lanore: [00:19:46] How much of that misunderstanding is driven by the fact that all of the all of the research done on female. HRT has been using you know, [00:20:00] methylated equine estrogens and and synthetic progestin 's that we know change hepatic landscape and increase the propensity of arteriosclerotic plaque buildup.

[00:20:11] And because we're really we don't see many people doing these types of long-term studies on bhrt do we.

[00:20:20] Dr. Elizabeth Yurth, MD: [00:20:20] No, I mean you're exactly right. There's even when people have so many women who are told by the doctors. You shouldn't take hormone replacement. You're too old. It's going to increase your risk of cancer.

[00:20:31] And and when you look at that piece, I tell my patients lives. Replacement can cause cancer and it can protect cancer from cancer and the key is two things number one use the right type of hormones and you're right. You don't want to use a synthetic hormone that's made from horse urine you want to use things that match what we're making in our own bodies and then number two one of the things for into that bowl Longevity Institute.

[00:20:57] We always look at how those hormones are [00:21:00] metabolized because one of the piece of whether your estrogens are going to cause cancer or even. Last room for males is how you metabolize is what Pathways is it going down. It's going down high-risk Pathways down for instance into a for hydroxy Esther owner.

[00:21:13] So

[00:21:13] Carl Lanore: [00:21:13] strong I was just gonna say Estrin is such horrible stuff. Absolutely.

[00:21:16] Dr. Elizabeth Yurth, MD: [00:21:16] It's a week never put people on hormone replacement. We are following their pathway metabolites and so that's that really is the key and that's that's what is every study. I read it overlooks is nobody is looking to see a we put women on all of these hormones but we have if we didn't number one we didn't dose them appropriately.

[00:21:34] We just stuck around the same dose or number two. We've never follow that patient to see how they were metabolizing and then work on how we change their metabolism to make it more into a safe safer state. So, you know so hormones I think done. We are going to protect you in general from from most diseases and you know the

[00:21:53] Carl Lanore: [00:21:53] in Friday at any age at any actually I feel the same way.

[00:21:56] I feel the same way because hormones tell your body. [00:22:00] It's young man. And and the body says, oh, I'm still young. I'm going to repair things. I'm still young. I still have a chance of procreating. I'm still young so it can't be bad. But as you point out, there's some things to consider when embarking on it the older you get.

[00:22:16] I want to take first commercial break. Now we come back. I want to get into dosing. I want to get into the affects. What women will experience we're gonna talk about men to because it works for men as well in higher doses. I also want to talk about ways to mitigate because there are ways to mitigate some of the quote-unquote unwanted effects.

[00:22:36] We're talking with dr. Elizabeth. You're with her practice is the boulder it's a time. So I got to put it back up here in order to Boulder Longevity.com. If you're in that area, you can reach out to her. She is a member of the international peptide Society. So, you know, she knows what she's talking about.

[00:22:53] Stay tuned. We'll be

[00:22:59] right back. Welcome back [00:23:00] we're talking with dr. Elizabeth your we're talking about PT 141. It is a peptide that increases libido. In both men and women but because it was approved as a drug for women who have a lack of libido and that have not gone through menopause yet. We're talking about that from that perspective today.

[00:23:21] So what is the dosing of PT? 141 for a woman? How long is it take for it to to start to work? How long does it last it's

[00:23:32] Dr. Elizabeth Yurth, MD: [00:23:32] a growing business actually one of the and you know from your experience you might have noticed this but. One of the hardest things I think about this peptide is bad that it does have a very very a lot of variability between people both from how long it takes to kick in and how long it lasts and even dosing some women will respond to a very small dose like a point 1 milligram kind of dose, you know, it's, you know one biscuit 1 milligram dose.

[00:24:00] [00:24:00] CeCe does which is one milligram some women need to and maybe even up to three men need more men often times that we were from 2242 really get an effect. The Miley see is a 1.75 milligrams. So they kind of cut between the 1 and 2 and you know, I found that that was a good

[00:24:18] Carl Lanore: [00:24:18] dose reliable. Yeah for everybody.

[00:24:20] Yeah, that

[00:24:21] Dr. Elizabeth Yurth, MD: [00:24:21] was for most women. I was like most of our women end up needing about a 2 milligram dose. We often have start them at one. The prescription says to take it 45 minutes before you want to have intercourse or you have relations with somebody and and I will tell you that some people it takes much longer than that and some people short.

[00:24:43] And then the length of effect can be anywhere from a few hours to As Long really Ed 72 hours in some people so it can really be a fairly long affect men don't usually get 72 hours of interactions, but I've had men who can

[00:24:58] Carl Lanore: [00:24:58] something goes

[00:24:59] Dr. Elizabeth Yurth, MD: [00:24:59] on and [00:25:00] on and on and that can be an issue, too. We usually tell people tell our patients when they first do it kind of do it at time when you don't have somewhere to go the next day when you you know, when you can actually play with the dosing a little bit and find out what is the right dose for you.

[00:25:15] How long is it going to take to kick in for you? You know, it's you know, I we tell people try about an hour before. And we start them at a 1 milligram and if they say I felt nothing we go up to a 2 milligram. Go

[00:25:31] Carl Lanore: [00:25:31] DJ you mean you just add a second. Who

[00:25:34] Dr. Elizabeth Yurth, MD: [00:25:34] did that? Yep, we just add a little bit more you from the for them to just take me away because different from vitally see which comes in a prefilled syringe so you really have choice of a 1.75 milligram right?

[00:25:46] When we describe it. We usually get our PT 141 from just a very, you know, a reputable Pharmacy like tailor-made for of us are

[00:25:53] Carl Lanore: [00:25:53] older. Maybe that's and that's and that's all we tell people like if you want interested in this you go to your doctor. Your doctor was reading about it have them [00:26:00] sign up for IPs International peptide Society get trained and they.

[00:26:03] Order this through tailor-made Pharmacy and Nicholasville, Kentucky and you have them prescription sent right to you and everything. Yeah, exactly.

[00:26:12] Dr. Elizabeth Yurth, MD: [00:26:12] What's you know, unless make sure that people know that really you'll you can go online and find PT 141 all over the place and you know, we've actually and taylormade's done this it analyzed a lot of these products and there are you either you know.

[00:26:27] Have very little of what they say. They have contaminants in them. So if you're just buying the stuff online keep in mind, you really don't know what you're getting. And so we really recommend that you work through a physician that actually has certification. We have our practice that you know to practitioners who are certified peptide specialist who do nothing but peptides therapies.

[00:26:47] So you really want to work with somebody knows what they're doing and you want to get these from a reputable Pharmacy like tailor-made. So when you get when our patients get that's a little. We can adjust the dose very easily. We say all the little bit [00:27:00] more pull up a little bit less. So that is a nice advantage over being able to speak in front of groups and.

[00:27:07] You know,

[00:27:07] Carl Lanore: [00:27:07] right exactly so I want to I want to inject no pun intended something into the discussion because this is going to play out in the rest of the discussion as well. So I've been playing around with Milano tend to for probably close to 20 years and and and obviously I took the opportunity to get some PT 141 and experiment with it last weekend.

[00:27:32] I started out with one in jet one milligram. The next day I added a second milligram and two days later. I did a full four milligrams and I felt different from each of those doses. I suspect that the the duration of onset is faster and its effects last longer and people with darker skin. Now, I have no evidence to prove what I'm saying other than I think that [00:28:00] if you have a much more evolved.

[00:28:02] Milano court and system your darker skin you have a lot more melanin receptors in general the four different receptors. I think that you will feel this faster and longer than someone who is like really, you know Nordic with you know translucent skin. We can see veins through and stuff like that. I think that they may need more they may need to wait longer for it to turn to or I could be exactly wrong.

[00:28:27] It could be the opposite that those with dark skin and not feeling as much. They like it but I think that the variation in in why we can't go well everybody just use this is related to the color of your skin.

[00:28:40] Dr. Elizabeth Yurth, MD: [00:28:40] Well, that would be interested in your it seems I haven't really we've been using PT 141 for a while.

[00:28:45] I guess I haven't really sort of registered try to register that I'd have to talk to some of you to my guy to do a lot with our all of our clients. Be see if they if they really notice that that I'm going to start keeping an eye on that and see it and I'll get back to you on that. Yeah,

[00:28:59] Carl Lanore: [00:28:59] I like [00:29:00] that.

[00:29:00] Yeah,

[00:29:00] Dr. Elizabeth Yurth, MD: [00:29:00] in terms of skin tone, you know is what is it will be interesting to see who you know, can we sort of? Come up with a person that we know is always going to use a little bit more a little bit less. So I'm gonna eye on that will start keeping a little notes on that and get back to you because it will be interesting to see I think theoretically it makes sense.

[00:29:18] I think that your hypothesis makes sense, theoretically so we'll see that sort of pans out.

[00:29:23] Carl Lanore: [00:29:23] Thank you, but

[00:29:23] Dr. Elizabeth Yurth, MD: [00:29:23] I gave it to last night who texted me this morning said I gave her one milligram. It didn't work at all and she is a more fair scare skin kind of, you know person. But then you and I talked a little bit too, but that there are other factors that play as well and one of those four instances just what your Baseline dopamine.

[00:29:40] Yes are you know, and we know that dopamine he is. Your sex drive is really really complex and especially in women men are much more simplistic. We know that that woman's Sex Drive is is really complex and there's a whole bunch of pieces that go in. That's why when we are [00:30:00] stressed and things like that.

[00:30:01] They have no sex drive is because stress and women rule really have a very distinct effect from. Men can be stressed in the whole world could be following in and you know, they still would want to have sex but

[00:30:10] Carl Lanore: [00:30:10] you know what but that is our evolutionary drive. That's why we that's why we have 300 million people in the country because Ben Ben just think about sex.

[00:30:19] That's it. I mean, you know, let's put us back in the cave. What do you think would think about sex? That's it, you know for that. Yeah.

[00:30:29] Dr. Elizabeth Yurth, MD: [00:30:29] Yeah, yeah, so, you know

[00:30:32] Carl Lanore: [00:30:32] the

[00:30:32] Dr. Elizabeth Yurth, MD: [00:30:32] whole dopamine system for instance is woman I was talking about last night. She also recently has had just this she's eating all the time.

[00:30:42] She's constantly constantly she woke up in the middle of the night to feed herself and which is unusual for her which would indicate. Dropping her dopamine for some reason. So yeah what me levels have dropped really low. We do think that the Moana court system. You know that when you take a moment has a lot of something that stimulates [00:31:00] will add a quart and that it does have a downstream effect on dopamine if your dopamine levels are very very low boosting them up a little bit may not help and so people who aren't responding or people who respond a whole lot probably different levels of dopamine play a role there as well.

[00:31:17] So those are all things. Interesting to kind of love

[00:31:19] Carl Lanore: [00:31:19] I'd like to offer something else. So if someone doesn't respond and it's idiopathic like we just can't figure it out. And we and you suspect it's dopamine related. I would say don't stop giving it to them because if we look at this from an evolutionary perspective right if you.

[00:31:41] If you keep stimulating that you start to Prime that pump the body will respond by adaptation and there that the new adaptation will the body will start to produce more dopamine in response to that. So I predict and one of the things that I pondered, you know about about [00:32:00] this. In fact, I had this discussion last year with with dr.

[00:32:02] Bill seeds. I said, I have a funny feeling that we could use Milano 10. To help people with Parkinson's disease if they received the problem with Parkinson's disease is 90% of people of misdiagnosed is a small sliver of people that really do have dopaminergic degeneration and and the Brain.

[00:32:25] Specifically the substantial Niagra but a lot of people have other neuromotor issues and doctors just say Parkinson's disease. That's a big problem today. I lived with my poor sister died because they treated her for Parkinson's Disease and they killed her with the with the cinnamon and the and the dopaminergic drugs at the ever.

[00:32:43] But anyway, I suspect that Milano tend to could be used and for that matter just being out in the sun. Moving to a sunny climate could actually be used to help people with Parkinson's disease because of its effect on dopamine [00:33:00] production because it needs dopamine to arouse you

[00:33:04] Dr. Elizabeth Yurth, MD: [00:33:04] night, but me exactly right that that all those things increase dopamine.

[00:33:08] We know that there's there's a lot of environmental factors now that are lowering dopamine. So when we kind of connect all these. Your Parkinson's patients to maybe there's a lot of environmental influences that are actually impacting dopamine levels and simply by doing things to raise dopamine and changing some environmental conditions.

[00:33:28] You can actually get Improvement but you're going about it. Maybe the sun is is dopaminergic and and will stimulate dopamine, you know lot of antidepressants remember are not dopaminergic and so a lot of our patients who are on antidepressants where you have high serotonin levels will serotonin is sort of aunt, Ida.

[00:33:46] S

[00:33:46] Carl Lanore: [00:33:46] of those

[00:33:48] Dr. Elizabeth Yurth, MD: [00:33:48] patients A lot of times you'll put those patients who are on antidepressants that are serotonin uptake Inhibitors and you give them something like like melanotan or PT 141 [00:34:00] and they don't have as much of an influence because their dopamine levels are so low and there's such a imbalance.

[00:34:05] So there's it's really complex and is why we kind of when we're looking at all of these things which seem simplistic. I'm going to go buy some PT 141 off the. Give myself an injection. There's a lot of complexity.

[00:34:18] Carl Lanore: [00:34:18] Yeah. Now this is a drug. You got to pay attention. So I also want to point out something else.

[00:34:23] You know, when I was a kid, there was a story that went around the streets of Brooklyn about Spanish Fly and woman took it and and she impaled herself and BT 141 is not going to make women do anything. Untoward or that they would not do characteristically. It's not going to take over their bodies and make them want to have sex with whoever answers the door next after the shot.

[00:34:47] You know, I want to I want people understand that all it does is is give you back the ability to become Amorous again. To get the feel those feelings, but you still have to have the [00:35:00] connection to the person that you're with just clarify that he's

[00:35:04] Dr. Elizabeth Yurth, MD: [00:35:04] interested actually the even when they were doing this in a rat model and and I'd actually no it was my choice.

[00:35:11] I think but I actually didn't know that mice preferentially had Partners. I thought they would just have sex with her. But Carolyn women dude, then not so much but the female mice do have preferential part. And when you gave them female Mouse PT 141 and they put multiple partners with her. She actually didn't want to have sex with the partner.

[00:35:28] They put her wish you would crawl through a little hole to try and get through her preferential partner. Right?

[00:35:32] Carl Lanore: [00:35:32] Let's start

[00:35:33] Dr. Elizabeth Yurth, MD: [00:35:33] with more to the story that we that it's not just generally going to make you go want to have sex with any guy walking down the road. There does seem to be some type of other deeper connection that you have to have and it stimulates that connection.

[00:35:46] But it isn't just that we do think that maybe you can take for instance marriages that are doing well and things like that and potentially using a combination of things like maybe a little oxytocin and people 141. You can actually sort [00:36:00] of recreate some love bond between those people.

[00:36:02] Carl Lanore: [00:36:02] Yes,

[00:36:03] Dr. Elizabeth Yurth, MD: [00:36:03] perfect.

[00:36:04] Carl Lanore: [00:36:04] Perfect. Perfect example of Bio hijacking right there.

[00:36:08] Dr. Elizabeth Yurth, MD: [00:36:08] You'll get two people kind of fall back in love, but it doesn't appear that you can just take that person stick them with anybody and. Then you know it doesn't work and that really is how complex the whole brain wiring system. Is that there?

[00:36:21] There's just too many pieces to this but and that's one really nice things about this. This PT 141 is it doesn't. It's not going to make you oversexed. It just creates a nice, you know, women have an improvement in sex drive improvement improvement in you know, in the whole experience really

[00:36:42] Carl Lanore: [00:36:42] orgasm.

[00:36:43] So I want to get that out to Chris. There's a there's a lot of women out there who have a tough time orgasming because they're there so self-confident conscious conscious not confident. They were self confident. They probably have more orgasms. But okay so self-conscious. About themselves how they look all I just wish I could lose ten [00:37:00] pounds.

[00:37:00] I don't want my husband to see me like this and they get so caught up in their head that they can't Climax and and actually PT 141 makes it easier to Climax and make the orgasm much deeper.

[00:37:14] Dr. Elizabeth Yurth, MD: [00:37:14] Right and that's true for both men and women. Yes, but guys, he women both reach orgasm more easily added and people describe a much much more euphoric stage.

[00:37:25] Carl Lanore: [00:37:25] Yes. So

[00:37:26] Dr. Elizabeth Yurth, MD: [00:37:26] with that so some of that has to do with increased basket full of some of it has to do with the neurochemical sort of balances that occur when you read about the whole neurochemistry involved with sex, it's it's sort of overwhelming and so just by doing this little simple tweak it. This is the books.

[00:37:44] I think that that the Manticore and system is so complex as you and I discussed but by setting all these little things you're affecting so many pieces of this what the what the other Advantage You Know Carl that that there probably is also an advantage to there seems to be [00:38:00] when you're using PT 141 a little bit of improvement and immune function a little bit of improvement in and sort of overeating and so even though it's focused a little bit more.

[00:38:11] It's treating the MC. Or system which is a little more focused on on the sex drive. It does have some effect on other systems as well. And so we have seen that it may be beneficially help over eating behaviors as well. It may make you just have a little bit better feeling during the entire day. So it's really a it's kind of a

[00:38:29] Carl Lanore: [00:38:29] well and it does does tan me a little bit not like one one-hundredth.

[00:38:35] Of what like I took four milligrams and I noticed I got a little tan like a little tent now if I were to take 4 milligrams of melatonin, I look like a black mole. I like black black mole right now instead of a skin. But but you know, it definitely tanned me and it definitely stayed around. It didn't just disappear right away.

[00:38:54] So I would say that. It probably will add a little glow to you. [00:39:00] If you're not as dark as me. I'm 14% Northern African. So I got to pray the tendency of that dark. But but yeah, it definitely tanju little bit. Let's talk about men for a minute. Right? So men need more like a for milligram dose and and unfortunately the negative or unwanted effects of this this drug seem to help that mean affect men more than women.

[00:39:25] Dr. Elizabeth Yurth, MD: [00:39:25] It's probably because of the higher dose the biggest downsides of PT 141 or by the lessee are the side effects and the biggest side effect is nausea. I mean, it's not great to be really horny and have a erection and be super super nauseous. Wait,

[00:39:40] Carl Lanore: [00:39:40] I got to go vomit. I'll be right back that's never what no one wants to kiss you if you vomit dr.

[00:39:46] Yours. I don't understand why. One so that's

[00:39:49] Dr. Elizabeth Yurth, MD: [00:39:49] the first thing and forty percent of people will get that. Usually it goes away the more you use it. So it does appear that there seems to be some adaption. So if you're [00:40:00] using it for a longer period of time that that side effect does sort of start to wane over time.

[00:40:06] And and usually it's earlier after the injection as well.

[00:40:10] Carl Lanore: [00:40:10] So yeah,

[00:40:10] Dr. Elizabeth Yurth, MD: [00:40:10] I'm Zach

[00:40:11] Carl Lanore: [00:40:11] 15 minutes 15 minutes 15 minutes after you take the injection. You may feel a little itchy. I just don't like not not even queasy T. I just don't feel right. What is it? Is it my stomach and then it goes away but here's the good news, right and you correct me if I'm wrong.

[00:40:26] If you're one of these people that it gets nauseous about everything if you take Alka-Seltzer gold. Which is equal parts of potassium bicarbonate and sodium bicarbonate about 20 minutes before the injection. You won't get nauseous that I learned that from dr. Bill seeds. And then also if you take like a half of a Dramamine, but that makes you kind of sleepy but if you're somebody who's oh, I'll just take a half of a Dramamine about 20 minutes before you won't get nauseous.

[00:40:53] If you're one of these people who's concerned about noisy.

[00:40:56] Dr. Elizabeth Yurth, MD: [00:40:56] Right, I think the sodium so using the sodium potassium bicarbonate [00:41:00] sodium bicarb to the oxides are gold is that is a nice trick. We have a lot of our clients on sodium bicarb anyway, because key people in more alkaline state has probably healthier anyway, so probably yeah

[00:41:12] Carl Lanore: [00:41:12] I said I take I take sodium bicarbonate twice a day and have been doing so for 10 years

[00:41:17] Dr. Elizabeth Yurth, MD: [00:41:17] now performance

[00:41:18] Carl Lanore: [00:41:18] is so there's so many things it's good for so minutes this.

[00:41:22] Yeah, yeah, so that's

[00:41:24] Dr. Elizabeth Yurth, MD: [00:41:24] that little trick the other side effect that some people get is headache and flushing and that actually can be alleviated. Sometimes by actually doing a little trouble baby aspirin about half an hour before, you know, the downside is you start to go. Okay. Well, I don't want my baby aspirin and I'm doing my PT 141 the fine.

[00:41:40] I'm ready to have sex. It starts to get a little bit complex. But if you really and like some most of these side effects of you sir. Can encourage people to kind of stick with this it most of them will go away. If you have somebody who just can't you know, I'm and I'm not going to do this and maybe 26 and those are little tricks that you certainly can use to help them

[00:41:59] [00:42:00] Carl Lanore: [00:41:59] along.

[00:42:00] I have a really good. I have a really good trick and this is because I've used melanotan to for decades now, I take my shot then I get in to take my shower. So when the what would the water stimulates. Endorphins epinephrine. It stimulates all of these hormones the water takes your mind off of why does my body feel weird because you know, you know, like if you tell me your hand you yeah.

[00:42:23] Yeah. Yeah, you tell me your hand hurts and I Jam your foot. Now your hand doesn't hurt because your foot hurts and so it distracts you and you get out and you're kind of read from taking a shower anyway, so it's not like, oh man, I'm all red. So anytime I use these drugs I take them and then I go take a shower right away when I come out I feel normal.

[00:42:42] Dr. Elizabeth Yurth, MD: [00:42:42] Yeah, that's a that's a interesting plan. Right? Because you know as our bio hijackers, lots of times would find different things and you sit there for a while and you just kind of wait to see what side effect you're going to feel and you know, it could be something completely unrelated, but you're thinking oh my God, I take my, you know left fingernail feels like it's growing, [00:43:00] you know, and those are just because you did something was completely different you sit there and you really literally wait for the side.

[00:43:06] And so I think by distracting yourself away from a lot of those side effects are going to be negligible. You're not going to notice of what you're saying. They're waiting for a side effect. And I think you know when we prescribe things often times, we really feel. Because we think about liability and everything else right?

[00:43:21] Are you getting this happened? This happened? This happened when I was just injected all of these thoughts into our clients heads and you know, and I think we sometimes maybe you know, people are so weary as they're doing it that they're going to have a side effect. So I do think that's a great thought is to give them something the shower is a great idea

[00:43:38] Carl Lanore: [00:43:38] to co-parent take your shot jump in the shower you come out you feel normal, but you've all of sudden you're aroused.

[00:43:44] I want to take a last commercial break and I want. Give my opinion of a tip that it's working. Okay, this is a good one. Stay tuned. We'll be right back with more of dr. Elizabeth. You're

[00:43:59] [00:44:00] welcome back. We're talking with dr. Elizabeth yurt from the boulder longevity in anti-aging Institute Boulder longevity.com for those of you who are in the Colorado area. The beautiful Colorado Colorado means it's colorful. It's a beautiful place. Yes. I have a lot of friends in Colorado keep from you.

[00:44:20] Gotta come out here. You gotta come out here. I'm afraid if I go there and I stopped smoking weed all never come home. But anyway, so, you know, the the thing that I've discovered with melanotan as well as PT 141 is you know, it's working for libido if all of a sudden you have this. Strange urge to stretch and yawn a lot.

[00:44:45] Oh, it's like when you know when you when you get a good night sleep you wake up in the morning and you stretch at actually means something to me. I've picked up on this route through life like their periods of time where I wasn't doing that I was like, I'm not sleeping. Well, I'm not doing well.

[00:44:57] I'm not aging well when when [00:45:00] you got the dose dialed in. You'll have this urge to just stretch and yawn and in women, they actually have this urge to tilt their pelvis and you'll see what I mean. When you when you hit the right dose. The term is actually lordosis and it's actually something women do when they're ready to well female females do when they're ready to mate.

[00:45:21] But if you can hear yawn it is not

[00:45:23] Dr. Elizabeth Yurth, MD: [00:45:23] a behavior. Yeah

[00:45:25] Carl Lanore: [00:45:25] arching

[00:45:25] Dr. Elizabeth Yurth, MD: [00:45:25] back. Yeah.

[00:45:26] Carl Lanore: [00:45:26] So yeah, you just feel like doing that and that, you know, okay. It's. Honey, let's go. Let's go home. Let's finish dinner and go home. Now. That's it. So, what did we miss? What would you like to add to this discussion today that we must.

[00:45:40] Dr. Elizabeth Yurth, MD: [00:45:40] I think I think just connect cautionary tale about how long the effects are going to last we had so Andrew acts as one of our one of our peptide specialist here and he has a client. Who's this big by the other guys working the long time. It is very eager about PG 141 and so he did a whopping dose and it really literally the, you know, the next [00:46:00] morning still drive has to go to work.

[00:46:01] He's still has a Russian, you know, he's calling Andrew trying to say, you know, what should I do? So because we really don't. So it could really you could still be having effects on it for sometimes 24 hours or so. Make sure you do do it at I want your first couple doses at a time when you know, you have the Leisure of maybe I'm in a rush off to work rush off to a meeting something like that.

[00:46:23] You have to play with this a little bit. Yeah, but it's fun and you know and just sort of try what those is the best what you know, what happens when you do a little too much really nice thing and you know, it's Carl and probably a lot of your listeners do but really the nice thing about peptides is it's pretty hard to do anything

[00:46:39] Carl Lanore: [00:46:39] bad.

[00:46:39] Yeah, if you have

[00:46:40] Dr. Elizabeth Yurth, MD: [00:46:40] good quality peptides like we talked about from TaylorMade if you have somebody who's kind of giving you them has told you how to dose them, you know, and that's not true all the peptides but for the most part, you know. I think if you do a little too much BT 141, you may have an unpleasant, you know have to have sex drive for too long.

[00:46:56] But in general probably not going to do too much.

[00:46:59] Carl Lanore: [00:46:59] Oh and [00:47:00] there's and there's so many other things that are horrible compared to having a sex drive for too long. You know, I actually I've told this story on the show, so you. Listeners who been listening to my show forever like oh, yeah. We're going to Carl's going to tell the story about the day.

[00:47:13] He was going through his divorce at a pick up his daughter, but I you know, I took a larger dose than normal by accident. I did my calculations wrong of Langton to. And I looked in the mirror. I was like, holy crap. I'm getting dark really fast and then all of a sudden I got an erection and and and and and if they're tired, I couldn't I couldn't I tried and tried I tried and tried and I tried again and I tried again and I couldn't get it to go down and I had to call my ex-wife and say look I can't picks it up today.

[00:47:46] I something came up. I like I really just can't I can't she was so aggravated with me but yes, but here's the thing. So I took one milligram last week on Friday. I definitely noticed an interest. [00:48:00] Let's say a heightened interest. Now, I already have is Eliza will tell you I'm a real pain in the neck.

[00:48:05] I already have a heightened interest, but I had like a noticeable heightened interest the next day. I added another milligram and it definitely felt more and then two days later I did four milligrams in one shot. And I did not get a spontaneous uncontrolled erection. I did get an erection right away.

[00:48:24] But if I was able to go, okay little Carl, we're not doing that now and it was able to if I would have taken six maybe I would have had that same experience like I did with that big dose of Milano 10. Yeah,

[00:48:36] Dr. Elizabeth Yurth, MD: [00:48:36] yeah, and you know and it's working many people always think about so well is this Viagra and memory it's not it's working in a very different mechanism.

[00:48:44] So it's Viagra or Cialis are working to vasodilate which is why they can be very dangerous, right? They can cause cardiac problems that can cause brain problems. They can cause priapism just extended erection because you've got this big huge phase of dilatation big blood flow [00:49:00] increase and that's what makes those drugs so risky so the nice thing about Petey 141 don't confuse it with.

[00:49:05] It's not working on that mechanism. It's not working because it's big huge, you know, increase blood flow where you're going to have a massive heart attack or it's working on a neurochemical basis. And so you really bite. If you increase your neural chemicals temporarily a little bit too high this there's tends to be not a big huge risk associated with that.

[00:49:24] He took a massive dose of Viagra. Yeah. There's going to be a huge risk with that. And so that's really one of the very nice things mean. This is a safe medication for people who can't take those types of drugs like Viagra. And sales because. They have cardiac issues or they've had a stroke or they had some underlying other dysfunction.

[00:49:42] And so these are really nice. This is a really nice medication for those people.

[00:49:48] Carl Lanore: [00:49:48] You know, there's a lot there's a lot of guys out there, you know with all these men's clinics open up everywhere, you know with all the different, you know different types of therapies that they're offering guys and obviously some of the [00:50:00] early offerings are pde5 Inhibitors and guys will take those and say, you know, I but I don't have any desire to have sex a pde5 inhibitor will make the the Machinery work, but you have to have desire for those guys.

[00:50:14] You can probably cut back on your Cialis to like seven or eight milligrams and take a take PT 141 and you can probably have a really nice weekend of sex,

[00:50:28] Dr. Elizabeth Yurth, MD: [00:50:28] right? That's it. And that's a great Point. They've done studies Now using using sales or Viagra. With PT 141 and they have a really nice synergistic effect.

[00:50:38] You one working on increasing vasodilation and one working on neural chemical basis put those two things together and you have increased libido increase sort of euphoria better better orgasm and a really nice quality rection, you know, and and for women to that their women have now are using Viagra, but the same thing you'll [00:51:00] increase visibility tation.

[00:51:01] You probably help with orgasm. It's not going to increase desire. So this is really one of the first medications that actually works on actually in

[00:51:10] Carl Lanore: [00:51:10] gasoline

[00:51:11] Dr. Elizabeth Yurth, MD: [00:51:11] wire.

[00:51:11] Carl Lanore: [00:51:11] We've been we've been waiting. We've been waiting for this for a hundred years. Yeah a hundred years. We've been waiting for something that woods but spontaneously increased desire right and and it's here now, but you gotta you know, you gotta just be careful with it.

[00:51:26] That's it. Listen. I want to have you back on. So we're going to come up with some other peptides in the near future and I will communicate with you and we'll do some more I'm experimenting with extremely high doses of oxytocin, right.

[00:51:40] Dr. Elizabeth Yurth, MD: [00:51:40] So oxytocin's of you know, we've been using that we use for increasing female sex drive for a while.

[00:51:44] We were using oxytocin, you know, because it was one of the ways you could and supplement works amazingly well to use oxytocin. I think it'll be fun to sort of see how those two play together.

[00:51:54] Carl Lanore: [00:51:54] Yes iíve been doing it. I've been playing with him CIA. So I've been I've been using extremely high doses of [00:52:00] oxytocin post workout because of the study that I talked about three or four years ago where they gave old rodents high doses of oxytocin.

[00:52:10] And injured their muscles and they injured the muscles of young rodents and they watch how fast they healed and the old rodents that got the oxytocin their muscles recovered even faster than the young so I thought okay oxytocin is good to take post workout. But the problem was I was buying pitocin which is you know 10, I used an ml.

[00:52:31] I got a high. I got a 10 milligram vial of oxytocin. 1 milligram is 500 I use now I've taken as much as 250 I use in one shot not a good idea talk about a head rush because oxytocin will raise blood pressure very quickly very quickly. But yeah, you

[00:52:54] Dr. Elizabeth Yurth, MD: [00:52:54] can use as a nasal spray to so it actually is relatively effective as a nasal spray it you use that kind of regular [00:53:00] basis.

[00:53:00] And

[00:53:00] Carl Lanore: [00:53:00] it's probably better to make it into the into the brain as a nasal spray, but I want but I wanted to hit my muscles because I want to be I want to be the old guy at the gym that everybody goes how old is that guy? So so so I'm actually using 50 milligrams to a hundred milligrams post-workout.

[00:53:17] I feel it when I take a hundred Tommy. I'm sorry 200 I use fifty to a hundred. I use post-workout one shot and I feel it. I feel it. I mean it's strong strong relaxing. My head feels like it's swelling up for about 4 or 5 minutes. But then all of a sudden I got this really sense of oh life is okay.

[00:53:37] Everything is just great. You think

[00:53:40] Dr. Elizabeth Yurth, MD: [00:53:40] it's helped me you're with the recovery or

[00:53:42] Carl Lanore: [00:53:42] yeah, I'll find the study and send it to you. So there's this study that we enter we interviewed the scientist three years ago. We probably longer than that. She did a study on Old rodents and young rodents rats and when they were trying to determine what they gave these rodents really high doses of oxytocin.

[00:53:57] And in fact, I had doctors write me and say [00:54:00] it's a silly study because you all we ever give people is 10/10. I use a mint, you know, they're talking about getting a woman to go into labor and it's like no dude. They you can take stronger doses than. But they gave these rodents. So what they did was they injured the quadricep muscle of The Young and the old rodents, but some of the old rodents they gave very high doses of oxytocin and then they looked at the muscles repair, you know, I sacrificed them and they were like, wow the old rodents that got the oxytocin their muscles recovered faster than the young rodents.

[00:54:34] And and so that my I did that interview because I'm like, well, we're enjoying our muscles every time we go into the gym and do some hard work. So oxytocin can help me so back then I started out by taking 10 I use post workout because like I said, I was getting pitocin, you know, like that's nothing but then I found a source of pure oxytocin and milligrams and I said, okay now I can get serious so I can take a hundred I use post-workout now, we're talking something [00:55:00] significant now we're talking something similar to what the rodents were getting.

[00:55:04] Dr. Elizabeth Yurth, MD: [00:55:04] And you've been doing that for how long now just

[00:55:05] Carl Lanore: [00:55:05] started just don't but I did take I did take some oxytocin with my second one milligram shot of PT 141 just to see what would happen. She'll be

[00:55:17] Dr. Elizabeth Yurth, MD: [00:55:17] really interesting to look at and yeah, maybe then that we can come up with a nice little mix of those two and patent that or something.

[00:55:23] Yeah,

[00:55:24] Carl Lanore: [00:55:24] I'd like that. I like that, you know hit see I'm still that 250-pound with store at except now. I'm only 225 pounds doctor your thank you so much for being on the show. We'll do this again. Okay. Thanks Carl. I taste it got

[00:55:37] Dr. Elizabeth Yurth, MD: [00:55:37] licensing about eight different states. So I have your listeners who want to work with us for my peptide specialist.

[00:55:42] We actually can work, you know Zoom conference and work with other people other people

[00:55:47] Carl Lanore: [00:55:47] list the states that your licensing please

[00:55:50] Dr. Elizabeth Yurth, MD: [00:55:50] and let's see, Arizona, Nevada, Wisconsin, Utah. California is two more [00:56:00] of them forgetting.

[00:56:02] Carl Lanore: [00:56:02] Okay, so you're pretty much out there on the west on the west coast. Yeah.

[00:56:05] Good,

[00:56:06] Dr. Elizabeth Yurth, MD: [00:56:06] Wisconsin, Chicago, Illinois.

[00:56:09] Carl Lanore: [00:56:09] Oh excellent. Yeah, Illinois. Yeah, just north of me. Fantastic. Okay. Well listen, thanks for being on the show and we'll talk to you soon. Okay. And that's all we've got for this week. It's been a great week. We've had a lot of great shows this one especially and we've got great shows planned for next week.

[00:56:25] So hope that you are around and you can catch them and don't forget. Oh, no, I forgot. No. No, that's next week. I'll talk to her by next week. We'll see you then.

[00:56:41] Take

[00:56:45] care [00:57:00] .



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Super Human Radio is the world's longest running broadcast dedicated to health, fitness & anti-aging with an emphasis on exercise, nutrition, and hormone management. This one of the most progressive podcasts for preventative & regenerative techniques designed to increase longevity. More

2908 Brownsboro Rd Ste 103
Louisville, Kentucky 40206

(502)-690-2200

SHR Logo

Super Human Radio is the world's longest running broadcast dedicated to fitness, health, and anti-aging with emphasis on exercise, nutrition, and hormone management. The most progressive source of information for preventative & regenerative techniques... More

2908 Brownsboro Rd Ste 103
Louisville, Kentucky 40206
United States of America

+1 502-690-2200