[00:00:00] Carl Lanore: [00:00:00] Welcome back to another episode of super human radio. Today is December 19th, 2019 as we near the end of the year. So since I do video now, everybody realizes my secret. I shave on Monday and then I don't shave again for the rest of the week. And when I used to just come in here and do the audio podcast, nobody knew.

[00:00:19] But I'm looking at myself and I look like an old codger. Of some sort. There's no doubt about it. I have to definitely start shaving during the week. Today a is a every other Thursday, which means that we have the re new life RX show. Uh, and of course Milo, Ronnie Milo is standing. Yes. The first step to changing your life starts with the renew life show

[00:00:42] Ronnie Milo: [00:00:42] with Adam Lamb.

[00:00:50] Carl Lanore: [00:00:50] It's not Adam Lamb. Adam graced us last week. Hey look at this. You're on the other side. We'll see if we could change this up later. I like being on that side. I don't know why. Cause I'm looking at the monitor [00:01:00] and it looks like I'm looking at you next to me, but now it looks like I'm looking away. How you doing?

[00:01:06] Oh wait a minute. Sorry. How you doing? I'm good.

[00:01:09] Ronnie Milo: [00:01:09] Good. No complaints. No complaints.

[00:01:11] Carl Lanore: [00:01:11] I know Adam was here last time. Amazing. You know, not that

[00:01:16] Ronnie Milo: [00:01:16] I was, I was traveling back to New York to see some friends, some family, uh, getting to the holiday spirit. Cause uh, you know, Florida here it's a, you know, it doesn't really feel like Christmas.

[00:01:24] It's 80 degrees out. Everything's green. Even though they hang out Christmas lights, it doesn't really feel like Christmas.

[00:01:29] Carl Lanore: [00:01:29] I know I went through that when I lived in Nevada and when I lived in Arizona. So I, yeah, I'm very familiar. Just so I'm, I'm sorry. If you grew up in the East, it's hard to look at a Palm tree with Christmas lights on it and feel Christmasy now.

[00:01:44] I guess if you grew up, uh, out on the West coast where you didn't have, you know, white Christmases, uh, then you, you're accustomed to it. But it took me a long time to even, I mean, I never really felt like it was Christmas.

[00:01:56] Ronnie Milo: [00:01:56] Right? Yeah. Still doesn't feel like Christmas. It feels like 4th of July right now,

[00:02:00] [00:02:00] Carl Lanore: [00:02:00] and let's be honest, the whole world feels that's the way Christmas is.

[00:02:03] Otherwise, movies like a Christmas story wouldn't be wildly successful. People would be like, Oh, that sucks. There's no Palm trees and sunshine. That's not Christmas. Right? So, and, and, and your mind, everybody thinks about Christmas being, you know, white and snowy and, and Christmas bells and people with Parker's and, and, you know, and skull caps on and playing in the snow and all that sort of stuff.

[00:02:25] They don't think about laying in the beach, laying on the beach and staring at a Palm tree with the Christmas lights and

[00:02:31] Ronnie Milo: [00:02:31] so on Christmas day.

[00:02:34] Carl Lanore: [00:02:34] Yeah. Yeah. Uh, so anyway, today's discussion is very fascinating to me. And I w I want to preface it by saying this. By and large, the bodybuilding community thinks that estrogen is the pox.

[00:02:47] Like, Oh, you know, estrogen attracts water or extra estrogen makes you fat. And, and science has proven that estrogen is both anabolic and, and, uh, light. Politik uh, [00:03:00] when we looked at research side by side with men who were given testosterone therapy and a placebo or testosterone therapy. And anastrozole and the men who got the answers all did not lose as much body fat.

[00:03:17] Uh, and quite frankly, they didn't gain as much lean mass as the group that just got testosterone and allowed the aromas  to occur. And the other thing that we could talk about since you and I were talking about trend bologna off the air, is we know that, uh, trend, uh, I, I gotta adjust something. I'm still learning this, uh.

[00:03:38] We also know that when they give cows trend bologne by itself versus a combination of trend bologne but plus extra dialed benzoate, the cows put on almost 50% more muscle mass with the addition of estrodiol benzoate. So you, it's hard to argue, um, logically that. [00:04:00] Astrogen is the POCs that it makes you bloated, it makes you fat.

[00:04:03] Uh, you know, it holds water and all that sort of stuff. It's gotta be something else because it doesn't, that doesn't play out in science. Right?

[00:04:12] Ronnie Milo: [00:04:12] Yeah. Especially when they, back in the day when the bodybuilders were making the tremble one, they used to go to the, uh, to the feed store and buy a feed, eject.

[00:04:20] Right. And then the process they would have to boil out or to get rid of the estrogen in there because it was almost estrogen dominant. So they would have to get rid of it to make it the trend acetate or an Anthea to where the case may be. So, uh, to your point, yeah, there's, there's a lot of estrogen. In Trenton alone, but you just got to get it out of there because

[00:04:38] Carl Lanore: [00:04:38] we know that that's the trend.

[00:04:40] Balone okay. So I want to just make sure we're clear about something. You can get Faena pellets that are just trend and you could put those in your cows, or you can brew your own Homebrew with them at home, but, but they also have, uh, uh, they also have feed a plus. Uh, as to dial benzoate, which was a separate [00:05:00] product.

[00:05:00] And you're right, the guys on the boards had a way to get the extra dial out, which I, I always thought to myself, there's gotta be some residual amount in there. And any residual amount would not be, uh, ideal. But now we think it, now we think it may be, uh, but, but you were able to get plain old. Faena pellets too, which we just trend blown.

[00:05:21] And cows don't put on as much muscle when they just use the trend by itself. So, so I guess it was Dan Dushane that popularized this idea that STR as the dial was a bad thing. Right? Cause he's the one who really introduced the use of the a then breast cancer drug. Which was aromatase inhibitors, right?

[00:05:41] Ronnie Milo: [00:05:41] Yeah.

[00:05:42] Carl Lanore: [00:05:42] And they do. And women too, and you know, let's be honest, there's a lot of female bodybuilders in females, very serious competitive athletes that have been convinced that they need to suppress estrogen in order to become more muscular and leaner, and they lose their period for years. Sometimes. [00:06:00] Oh yeah.

[00:06:00] Uh, and, and this is not a good thing. I get it. You're, you're more driven by success than health. But that is going to change when you reach a certain age and you realize, Oh wow, death is just up there now. You know, I'm not all the way back there anymore. And you go, Oh, look, what can I do to stack the odds in my favor that I'll live longer?

[00:06:22] And, and that a suppression of estrodiol is, is, is so. Harmful to a woman's health. So harmful.

[00:06:31] Ronnie Milo: [00:06:31] And we, so we get a lot of competitors come through the clinic and then I'll see their blood work and I'm like, did you just compete? And they're like, yes. I'm like, your estrogen's in the toilet, right? Like, what do you mean?

[00:06:39] I'm like, it's 11 it's 12 you know, it's, it's 20 and they're like, how? So I said, are you taking firms? Are you taking aromatase inhibitors? Well, yeah, my trainer had me do it because he says, it makes me leaner and it makes me this. I said, all right, well, there's a deal. We got to get them back back up, right?

[00:06:55] We've got to get it back up and get them, get it back up quick, because that's going to affect over a health and wellness. [00:07:00] And then obviously the post show rebound. We all know how that goes, but then also takes your body eight months to normalize regularly without any medications on board to get the estrogens back to normal levels.

[00:07:10] So well,

[00:07:12] Carl Lanore: [00:07:12] and this whole fallacy about water retention. Layne Norton dispelled this years ago. Um, you know, lane was an accomplished competitive bodybuilder. And, and I, I'll stand to be corrected, but I don't think lane ever did real gear. I mean, he may have tried some over the counter or, um, uh, pro hormones back in the day when we had access to them.

[00:07:38] I don't know. And I'm not saying that, and I'm not suggesting that lane is a Saint, but I'm pretty sure that when lane competed, he didn't use gear. But what I do know about lane is. He would get so paper thin, his skin would get so paper thin and he would be so. Grainy that his body looked like it was made out of solid [00:08:00] mahogany.

[00:08:00] It really did that, and he came on my show years ago. This is like, I don't know, 10 years ago, 11 years ago, I mean, lane was on my show before he even had his PhD and before he was Dr. Lane Norton. And. He came on the show and said, no, the secret is to continue to drink water all the way up to your competition.

[00:08:18] He would actually up his water as he got closer, when everybody else started taking diuretics and trying to dry out, and he was dry and grainy. So clearly there's another way to do this thing, you know what I mean?

[00:08:31] Ronnie Milo: [00:08:31] Absolutely. Well, I think the misconception is when you're going through a bodybuilding show, right?

[00:08:35] We have the androgens pretty high, right? To retain the muscle, especially in a caloric deficit state, that the misconception is that more androgens create more water retention to get rid of the water retention. Do we need to use an AI? And I was, I was a part of that, you know, back in the early bodybuilding days in the 2010 2011 and you know, you're eating aromatase inhibitors a daily.

[00:08:58] Right? W we didn't know [00:09:00] how bad it was for us, right? And we figured out that what makes us leaner makes us harder. But in that case, to your point, it doesn't. Right. And the best I've ever looked on stage was actually drinking water, like a gallon of water before I went on stage. And I look grainy, I look hard, I look, you know, tight while everybody else is looking watery because they eliminated the water and they're trying to manipulate sodium intake and potassium intake and then they're trying to carb load.

[00:09:24] But, um, you know, to your point. He was right. He was right, right on the, on the money when he said that, you know, drink water before you go on stage,

[00:09:33] Carl Lanore: [00:09:33] he tried. He said he literally went from one gallon to two gallon and two gallons to three gals. I remember this distinctly and, and he drank water right up until the day.

[00:09:43] The moment he stepped on stage and there were few people that was dry and grainy looking. All right? As him standing on that stage, I mean, he won a lot of competitions because his conditioning was just amazing. But, but so now let's, let's, so this is a good [00:10:00] discussion, right? Can estrogen is very misunderstood.

[00:10:02] It's clear. Now we know that, right? It's misunderstood by modern medicine. It's misunderstood by athletes who think that it's, it's the pox. We now know that it actually is at a Bolick. We now know that. Oh, it is light ballistic. We also know that Astra dial specifically, uh, is highly anti-inflammatory.

[00:10:23] There is a receptor on every cell on your body called a FAF, fiberblast activation factor receptor. And, and during times of trauma, Esther dial can dock in that receptor and completely and immediately suppress. The inflammatory response of blunt force trauma. So like if you're in a car and you don't have your seatbelt on, you get in a car accident.

[00:10:48] Your head hits that glass and you suffer severe damage to your skull, and the and the underlying brain androgens are immediately aromatase in the [00:11:00] brain to become extra dial to start to that early emergency. First responder to stop, to try to, okay, we got to keep this brain from swelling anymore until we can do something about this.

[00:11:11] And that's Esther dial. So we know that Esther dial is also highly anti-inflammatory, and we talk about inflammation in every disease today,

[00:11:18] Ronnie Milo: [00:11:18] right? Yeah, absolutely. Okay. Possible for transcription of the RNA and DNA because of the ERB. Well, the era estrogen receptor site as as what it does actually, it goes from testosterone to aromatase and to the ER estrogen receptor into the transcription of the RNA DNA.

[00:11:35] So it's for growth, sexual function, responsible for a whole myriad effects. Do you know, uh, for human function

[00:11:43] Carl Lanore: [00:11:43] and now and now and now, a new one, a new one? No. All of estrogen on soft tissue, more specifically on tendon. And ligament function and metabolism. And they even show a correlation to the tensile strength of tendons and, and the, [00:12:00] and the, the failure load that can be reached.

[00:12:03] So let's talk about this study. This study was a multicenter study done in Germany and Bulgaria. Right. Go ahead. Yeah,

[00:12:09] Ronnie Milo: [00:12:09] they're just starting to study. It was from the journal of a steroid, biochemistry and molecular biology. It was done back in 2017

[00:12:17] Carl Lanore: [00:12:17] and

[00:12:18] Ronnie Milo: [00:12:18] what we try to do at, at renew life is try to stay ahead of the game cause we have a lot of patients that we deal with.

[00:12:24] And a lot of the concerns that I get on a daily basis is men and women. Where am I? Estrogen levels, right? Are they low? Are they high? What can I do about them? What can I do about this? So we have to stay ahead of the game by making sure that we are controlling the correct estrogen levels for them, for ha, for optimal, uh, you know, health and longevity, right?

[00:12:42] So we have to stay on top of this. So I have to study all the time. You know, I'll put a 16 hour day in, you know, with patients, but then I have to spend a little bit more extra time doing studies and stay on top of it. So I ran across this one and it was the effect of estrogen on tendon and ligament metabolism function, as you said.

[00:12:57] Right? And this was shows that the [00:13:00] study was back in 1996 and they took an ACL ligament and they biopsied it, and they showed that there was estrogen and receptor sites on that. Then they started to figure out that there's more estrogen receptor sites and you know, human tissue, obviously muscle bones, ligaments, cartilage, tendons, and then they started to do this study on this, which, uh, which you have a essentially copy of.

[00:13:24] And then it just goes into the depth of saying that, you know, estrogen is really responsible for, like you said, tensile strength and in the ligaments and the tendons and bone transfer on bone, um, uh, you know, replication and that nature and what they're showing that is that it helps increase collagen production.

[00:13:43] Right. And it helps decrease inflammation. Like you said, it also helps healing. And then it also helps with joint stiffness. Now I can relate to that too, because when I was getting ready for bodybuilding shows and I was running a lot of aromatase inhibitors back, you know, probably two to three weeks off from the [00:14:00] show, my

[00:14:00] Carl Lanore: [00:14:00] joint achy joints.

[00:14:01] Absolutely.

[00:14:03] Ronnie Milo: [00:14:03] The bottom of my feet felt like you're walking on glass. Like when you go to the gym, it's just your, your, your ligaments and your joints

[00:14:09] Carl Lanore: [00:14:09] just hurt.

[00:14:10] Ronnie Milo: [00:14:10] And then also there's a lot of estrogen receptors in the brain. So if you eliminate a lot of estrogen, your thought process is a little bit different, right?

[00:14:17] So you're, you're looking and try to tie your shoe and it takes you about 15, 20 minutes trying to figure out how to tie your shoe because your body needs estrogen, right? So these studies show that estrogen is very responsible and, uh, for these different functions in the body. So that's, that's what the study is all about.

[00:14:34] And it's a, it's a pretty in depth, uh, read to you

[00:14:37] Carl Lanore: [00:14:37] if you went over it. Yeah. And, and I, I loved some of the, the, the information in there that, that kinda correlates to the other side to where some of these troubles are coming from. And we have some evidence of athletes, uh, that have used lots of aromatase inhibitors in suffering major, uh, tendon.

[00:14:56] Uh, failures. And so, you know, we know, [00:15:00] I mean, people who are stripping, uh, quadricep muscles off the bone, it's not, it's not everybody thinks all, you know, what they love to say is all, when you do steroids, the muscle gets stronger than the, uh, then the ligaments can hold onto. But some of these athletes that this is happening to, they've been training for 10 years.

[00:15:18] No, it's not, that's not the problem here. The problem is that a tendon, metabolism and tendon, a repair is not happening at the rate that it needs to happen. Because a lot of these guys and gals are suppressing their estrogen levels, most notably the estradiol levels. And you also, when you talk about collagen, you know, um, you, you, I'm not wanting to talk cause I have a face like a shoe.

[00:15:43] I'm 61, I'm 61 years old. Um, you see a lot of young. Bodybuilders, men and women, they're in their thirties and their faces look old. And, uh, yeah. And it's because these, they're the [00:16:00] imbalances in, in estrogens and androgens in their bodies for long periods of time. And especially if they're suppressing those estrogens even more so.

[00:16:09] The collagen breaks down, your skin gets old, it stretches you, get, you get stretch marks in it. It sags under the gravity before it's supposed to. It's one thing if you're in your sixties but if you're in your thirties and you're starting to see this already, not a good thing.

[00:16:24] Ronnie Milo: [00:16:24] And then I'll see a lot of people too.

[00:16:26] So instead of identifying their hormones, what they'll do is I go get Botox. They'll get fillers to fill out the faces to make them look more youthful. But at the end of the day.

[00:16:35] Carl Lanore: [00:16:35] The issue

[00:16:36] Ronnie Milo: [00:16:36] is hormonal,

[00:16:36] Carl Lanore: [00:16:36] right?

[00:16:37] Ronnie Milo: [00:16:37] Also too, if it's, if somebody is estrogen dominant, predominantly females, it could have the same effects as low estrogen in males.

[00:16:44] You'll start to see breaking down in the ligaments. You'll start to see a fracturing of bones a little bit easier, you know? Um, and then also, you know, stiffness in the joints because of the inflammation, maybe like arthritis and stuff of that nature. So,

[00:16:58] Carl Lanore: [00:16:58] yes, and [00:17:00] that's a big one. So even rheumatoid arthritis.

[00:17:03] Uh, there is a component, uh, of estrogen's role in both the development and the suppression of, of the disease. And, and, you know, you, you got a lot of women today who are going through early menopause. Uh, I, I mean, I'm shocked it guys are going through early andropause too. Don't think it's just women. We are under attack biochemically today.

[00:17:27] We have things that are suppressing. Natural production of our hormones. And then we have things that are interfering and competing, uh, that are, that are, that are, uh, uh, forms of, of molecules that act like androgen to act like estrogens. They could be from plant sources or they could be from chemical, uh, chemicals.

[00:17:46] So we have, uh, we have a lot of people today that are in their thirties. They're starting to display. Signs of, uh, hypogonadism and men and, and, uh, and, and, and, and, [00:18:00] and women who are starting to show the early signs of peri-menopause where their periods are getting irregular and they're starting to have hot flashes already and all of these symptoms, this is not a good thing when you talk about bone and a soft tissue health, these are some of the first things to show signs that something is wrong with this person.

[00:18:22] Right?

[00:18:22] Ronnie Milo: [00:18:22] And we're starting to see, um, you know, more people, you know, at a younger age, come in with low hormones, whether it's estrogen or testosterone. I think I had one the other day and I was 23 and I asked him, have you used hormones in the past? They said, no. I said, are you under a lot of stress? They said, yes.

[00:18:37] I said, well, there you go.

[00:18:39] Carl Lanore: [00:18:39] I don't know that it could all be explained the way from stress. I gotta be honest with ya. We know the body is so resilient that at a young age, it's designed to keep. Everything's stable during what is considered the, the reproductive years. You know, your body will overcome a lot.

[00:18:54] I think it's, I think it's stress, but I also think it's things that they're eating [00:19:00] that are, that are, that are, that are hormonal mimetics I think it's, I think it's, uh, their sleep patterns or the quality of their sleep. Uh, there's this, this is, uh, this is multifactorial and  we actually have, you know, they had the plague wiped out.

[00:19:20] Millions of people add the red death, wiped out millions of people. Every time. One of these, these, uh, uh, mass killers came along. We actually had a Renaissance because with all these people, what they had with the herd thinned, there was like this new, uh, this new emotional. A movement in the, in, in these countries to, to, to, to do better, let's say.

[00:19:45] And so we don't have that quick, like three months, 17 million people, uh, dead. But we do have, is it thinning of the herd of a different type. Right.

[00:19:56] Ronnie Milo: [00:19:56] And it's a lifestyle too, right? You know, the stress does [00:20:00] contribute to a couple of different things. You know, obviously, you know, high cortisol levels, but then at the end of the day, of, to your point, it's a multifactorial because it's all lifestyle.

[00:20:07] It's, you know, their foods or you know, if they're sedentary or not, if they're under a lot of stress, if they're, you know, they're not doing the right things for their health, and you start to see declining of the hormones that are earlier age because of that. Plus, you know, if you take. Somebody 20 years ago we didn't, we didn't have as much stimulation as we have now with social media and everything's under stress now because everything is

[00:20:28] Carl Lanore: [00:20:28] just the caffeine consumption.

[00:20:30] Today. I just read a great study. Here's a, here's a tid, but you'll love this one. Women who consume 300 milligrams of caffeine a day or more have functional changes in the vitamin D receptor that that makes vitamin D. Ineffective. So you can go and have your 25 hydroxy tested and your doctor go, wow, you're in the seventies you're rocking.

[00:20:57] But if it doesn't activate the [00:21:00] receptor, it doesn't matter how much vitamin D you have in your body, you're still going to develop osteoporosis. So if you're one of these now, now think about this. It's probably somewhat true in men too. I mean, eh, you know, with the amount of caffeine we're consuming today.

[00:21:17] It's probably true in men too, but maybe their threshold is high or maybe when they get to a thousand milligrams and there's plenty of guys out there that are drinking a thousand milligrams a day or more, just the few boutique coffees that they have.

[00:21:32] Ronnie Milo: [00:21:32] Well, if you, if you're the deficient right and you're in, your hormones are low, then you're a perfect candidate for osteoporosis

[00:21:39] Carl Lanore: [00:21:39] and other disorders.

[00:21:40] We're now seeing that the, this, this, uh, um, this perfect storm. I hate to use that term cause it's been so overused, but this perfect storm that we w we see in the population today is causing all of these diseases we have. Have you ever asked why every frigging body has obstructive sleep apnea? Have [00:22:00] you ever asked, why does everybody have neuropathy today?

[00:22:03] Even if they're not diabetic? Have you ever asked, why is everybody's gut so distended? Why is lean people, they look like they're three months pregnant? If you're not asking these questions, you're not noticing it in the population. You are actually one of the people who may get thinned out someday. You got to start paying attention to this stuff because there is something afoot in our population.

[00:22:26] Yeah.

[00:22:26] Ronnie Milo: [00:22:26] And it's funny, it's funny you say that because how does discussion up in New York was one of my friends, and, uh, he started to get into physical culture and he started to understand what we do. And I said, the next time you go to a grocery store or somewhere that has a lot of people, don't judge, but just look,

[00:22:42] Carl Lanore: [00:22:42] Oh, we watched Ronnie Milo, but he usually comes right back very quickly.

[00:22:46] Very cool. You just wait, wait, wait. You said you don't, you said I missed you after you said you just look.

[00:22:52] Ronnie Milo: [00:22:52] Yeah. So don't judge people. Well, I said, don't, don't judge people. Just look and see how many people that appear to look sick, [00:23:00] right? They're overweight. Uh, they have some kind of issue going on, right?

[00:23:04] And, and just observe. And he came back to me and he says, man, I didn't never notice. But there's a lot of people out there that have some kind of issue. And I said, it's, it's crazy. Right? And for us, we want to help them, right? We want to walk up to them and be like, Hey, I can help you, but we can't.

[00:23:18] Obviously this day and age, they take that as offensive. Right, but we're just trying to help them, but they're like, no, I'm fine, or whatever the case may be. But he was, he was like, man, you're really right. When you go to the grocery store and you look around and just looking at what people have in their grocery carts, right?

[00:23:33] And you just want to say something, but you can't, you know? And he's like, man, it's, it's pretty crazy.

[00:23:39] Carl Lanore: [00:23:39] We're gonna take a quick commercial break. When we come back, we'll pick up this subject on the other side, talking about this recent study and some other implications of tampering with your estrogen levels.

[00:23:50] Uh, especially if you're a man. I mean, we don't have enough estrogen to begin with, quite frankly. Super bright back. [00:24:00] Welcome back.

[00:24:03] Ronnie Milo: [00:24:03] I found an old shirt, mist,

[00:24:07] Carl Lanore: [00:24:07] ballers. Aggressive strike Mike Mala shirt. Old school. Yeah. This year it's about 10 years old. Um, yeah. Yeah, easily. Maybe longer. I, you know, I, I dug out a bunch of clothes.

[00:24:19] Winter stuff and I found this and I'm like, that's not a winter thing. Well, how did that get in there? So, yeah.

[00:24:24] Ronnie Milo: [00:24:24] I don't have any winter clothes.

[00:24:26] Carl Lanore: [00:24:26] Yeah. You don't need any winter clothes.

[00:24:29] Ronnie Milo: [00:24:29] You're wearing tank tops and love. You're on the show.

[00:24:31] Carl Lanore: [00:24:31] Yeah. Uh, I've, I've been shirtless before. I started doing video when in the, in the middle of the summer.

[00:24:38] It gets so hot in the studio because the air conditioning just sucks. And then I've got all this equipment around me and uh, and yeah, it's, um, it's brutal. And so I would sit in here shirtless and leave the door open and people would walk up and down the hallway and they'd look in the eye. The woman who runs this, um, property, Leah, um, she would take people to look at office [00:25:00] space and they'd walk by my studio and they would whisper, Tara, is he naked?

[00:25:06] She go, no, he just takes his shirt off cause it's really hot in there for him. Cause I'd be dripping sweat. I can't do that on video. That's not going to happen anymore. Now that I'm doing video. Yeah. So anyway, um, you know, uh, we keep thinking estrogen is something bad and. We know that it's not now. It's really a small percentage of people now that I think estrogen, they think it's estrogen is bad, and that's pretty much the ones in the bodybuilding community that had been using things to suppress their estrogen.

[00:25:36] I think the rest of the rest of the thinking population knows that this is, it can't be bad. It's gotta be good. Especially when in men, we developed Parkinson's disease like five times greater rate. Until women go through menopause and their estrogen duct drops, and we know that estrogen protects the brain.

[00:25:57] We know that it specifically protects the brain. We [00:26:00] know in the development of Parkinson's disease, they use rodents and they infuse one group with M P T P, which causes Parkinson's symptoms spontaneously that fast. And céline and the other group, they gave MPTP and Esther dial and the group that got the S, the dial took ix weeks to succumb to MPTP and the group that got the saline, they developed Parkinson's symptoms immediately within, within, you know, hour or so.

[00:26:37] Ronnie Milo: [00:26:37] Well, if you look at Parkinson's, inflammation of the brain, right. Downregulation of mitochondria in the brain. Right? So that's an absence can communicate correctly. So extra dial will decrease inflammation in the brain. So there you go. There's your fix.

[00:26:50] Carl Lanore: [00:26:50] Yeah. And you know, and I've always wondered why the people within the Parkinson's community aren't doing something about that.

[00:26:57] Right. Oh wait. Oh wait, let me [00:27:00] guess. Wait. It's, it's, it's a hormone. They're dangerous weight. We've had them in our body since the moment we were born and, and we have hormones and they seem to be fine, but as soon as you want to treat somebody with a disease, with a hormone over the last dangerous, yeah, that's a hormone.

[00:27:18] Ronnie Milo: [00:27:18] I think they did a couple of studies on some, a synthetic estrogen, the restaurant aisle, and not one that caused cancer because it was from that quinine. Uh, it wasn't a naturally occurring, wasn't, it wasn't a

[00:27:28] Carl Lanore: [00:27:28] biogenical hormone. Right? I think course. Because for medical, for for research purposes, all they're going to use is Premarin, right?

[00:27:36] That's the one that Premarin is, not only is it, not only is it an equine estrogen, but it's also methylated to resist. Breakdown by the liver, which actually causes thrombosis. It causes thrombotic index to go through the roof. It causes clotting. It causes the development of cysts in the liver. It's horrible, horrible, [00:28:00] horrible stuff.

[00:28:00] They got no problem putting women on that stuff, but they won't put them on a, an estrogen cream. God forbid. Right?

[00:28:06] Ronnie Milo: [00:28:06] And that's where people go. They go right to that study and they say, well, they're sentencing me. They're like, well, estrogen causes cancer. I'm like, no. We'll look at the basis of the study on the control of what the study, what the, what the study was from, you know, from a synthetic, you know, like you said, like when I'm, you know, estrogen,

[00:28:21] Carl Lanore: [00:28:21] we don't use it.

[00:28:22] Well, and if you apply some critical thinking, you realize that it, if estrogen caused cancer. If that was an absolute fact that every pubertal girl would develop some form of cancer. When estrogen just goes through the roof at her booby start growing and hair starts growing on her, you know, her vagina, and she's turning into a young woman, we would see the highest level of cancer rates at that age, right?

[00:28:46] They're like, Oh my God, estrogen. It's causing cancer and all these girls. Right.

[00:28:50] Ronnie Milo: [00:28:50] Especially when the doctors birth control. Right?

[00:28:53] Carl Lanore: [00:28:53] Yeah. So we talked about that recently about birth control pills. I mean, we've talked about birth control pills [00:29:00] on this show over the course of 14 years, quite a bit. And the takeaway is progestin based pro progestin based birth control pills are horrible for women's bodies.

[00:29:10] Horrible. They lead to the onset of dementia in a dose dependent and length of time dependent basis. The longer you're on a progestin based birth control pill, the more sure, assuredly you will develop dementia. That's been proven in a very big study of over 30,000 women.

[00:29:30] Ronnie Milo: [00:29:30] They don't want you to know that.

[00:29:32] Carl Lanore: [00:29:32] Oh, they tell you, forget about that. Oh, in a couple of years, you'll forget it anyway. You won't have, and you won't have a memory either. I mean, so, so those hormones are fine for them to give you that, that is synthetic or, or come from animals. But God forbid they give you a biodentical. That's, that's just dangerous.

[00:29:51] That's, that's reckless. Right. So, um, in summary, this study does show. That [00:30:00] more research needs to be done because they have shown that there is a direct correlation to estrogen's availability and the strength, uh, and metabolism of soft tissue and more specifically tendons and ligaments. Right.

[00:30:16] Ronnie Milo: [00:30:16] Right. So yeah, so basically this study was based on estrogens, right?

[00:30:20] And we know there are three parts of estrogens after dial, estriol, and, uh, Asteron.

[00:30:25] Carl Lanore: [00:30:25] Asteron, right?

[00:30:26] Ronnie Milo: [00:30:26] So they're, they're basically coupling all three and CLC, which is a estrogen like compounds, so they're not able to specifically target what estrogen is responsible for these. So that's why. There should be more studies out to do this.

[00:30:39] And like I said, this was back in 2017 when they studied it. So I'm sure we'll start to see more studies starting to come out to light. Uh, basically specifically targeting what estrogens is responsible for these things. And it could be all three, right? It could be all three. Um,

[00:30:54] Carl Lanore: [00:30:54] you know, uh, and you're right.

[00:30:56] We have this attitude that estradiol is the only good one. [00:31:00] Estrone is the only bad one. An estriol, which is the most abundant, is of no real consequence. We also thought that about sex hormone binding globulin. You know, every time we act cavalier, like, Oh, this is the only good one. Well, why would the body have the other two, 2.5 million years of evolution?

[00:31:18] Why would we have the other two? They play a role. There's no doubt about it.

[00:31:23] Ronnie Milo: [00:31:23] Right? Absolutely. Yeah. I mean, they all all play a role and they all come down to one thing and it's cholesterol, right? They're all cheated from cholesterol and very important to understand, especially with this new trend of this plant based diet stuff out.

[00:31:38] Cause I get phone calls every day.

[00:31:40] Carl Lanore: [00:31:40] It's scary. We're going to wait. We're going to make the population sicker. Then in the 70s when we told them that red meat and fat was bad.

[00:31:48] Ronnie Milo: [00:31:48] Right? So, I mean, I get the phone calls all day. I watched this movie, I want to go plant based. What's your thoughts? And I'm like, listen, one thing, we need cholesterol, because cholesterol is a feeder for all the hormones, right?

[00:31:59] And estrogen, [00:32:00] testosterone, a SHBG, all the, all the hormones that are needed. And when you start eliminating those, then you start eliminating hormones and you start to see a lot of different problems in the system. So, um, you know, with that said is, you know, they're all, they're all derived from cholesterol, right?

[00:32:15] So we need these, you know, we need a good cholesterol in the system to create these hormones. If not, we'll have an imbalance. And then obviously you'll be calling me and I'll be doing your blood work and make sure that everything is

[00:32:24] Carl Lanore: [00:32:24] normal. It's funny you mentioned this too. Uh, so this weekend I was cleaning out a room and I actually gave away pumping iron.

[00:32:34] Now I watch pumping iron probably. Two or three times a week for at least a decade before I went to train. I watched that, or I watched, uh, uh, the unbelievable with Ronnie Coleman. I watched those two videos to pump me up to train. But after, I realize now that Arnold is successful, right? But success does not mean [00:33:00] that.

[00:33:00] A person is intelligent. I know a lot of really stupid people that have made a lot of money. I know a lot of corrupt people that have made a lot of money and I know a lot of people who, if their objective is just to make a lot of money, they, they will find ways to do that. And Arnold, his, his promoting an obviously nutrient deficient diet on our unthinking population who follow.

[00:33:27] Uh, celebrities. Every suggestion today, we're going to have a lot more sick people look. So people said, Carl, everybody's weighed in on the game changer. We know you should do a show. I'm not going to do a show about it, but I'm going to say this. The vegan diet is not an appropriate diet for humans, because if it were, we would have been vegans, and we're not.

[00:33:54] Right. And, and we can't be obligate vegans. We cannot, if you eat [00:34:00] just a vegan diet, you absolutely unabashedly, I will not take the statement back, develop nutrient deficiencies that will lead to diseases and early death. If you are a strict vegan and, and I'm talking about without supplementation, without you going.

[00:34:20] And buying things to put in your body to make up for all the harmful damage you're doing by leaving those things out in your diet. We didn't have GNC, you know, 50,000 years ago. Okay. So we couldn't, we didn't have the luxury of supplementing, so people who were vegans, it's even in the Bible, I just posted this somewhere.

[00:34:44] The Bible talks about vegans being weak. Physically weak because they were weak. They were starving themselves to death for some righteous attitude about animals or whatever it is, and that's fine. I don't care why you do it, but just [00:35:00] know this. Telling people to go vegan is reckless. It's harmful. We know that vegans have the greatest amount of mental illness compared to omnivores.

[00:35:13] Been proven three times in studies, more recently. One that shows that vegans are depressed and the vegans will tell you, well, that's because we were sick already, and we'll use the diet to get better, but they're not getting better. They're getting sicker. Right? So I have lost respect for Arnold. I don't care what he does anymore.

[00:35:31] I am not going to give him any bandwidth because he is just a shill. He's just trying to stay relevant. So he's saying what the crowd wants to hear. That's all he's doing.

[00:35:42] Ronnie Milo: [00:35:42] Well, he's all, it's all about making money, right? Cause if you look at the director, James Cameron, right? If you look at what he does, he is an investor in a, I think a plant based company, right?

[00:35:52] So that's his agenda as a push this plant based to drive some more money to.

[00:35:56] Carl Lanore: [00:35:56] But, but he will say to you that he's an investor in that because he believes [00:36:00] that the plant based diet is better for people and he's doing it for the right reasons, which that's great for him. But he's wrong. He's absolutely wrong.

[00:36:09] And, and science shows this. And an evolutionary history shows this, that they are wrong, but they are going to kill a lot of people and I'm okay with that. This is, this is selection pressure folks. We're watching selection pressure. Remember I've been saying on the show for years now, the new selection pressure is where you get your information from and what things you choose from that information to put into your lifestyle.

[00:36:35] And we are going to have a lot of sick people. A lot of sick people and probably 200 years from now, we're going to have a thinning of the herd and really what's going to be left the critical thinkers at the trip.

[00:36:45] Ronnie Milo: [00:36:45] Yeah, and that goes back to our conversation, right? You start eliminating cholesterol food and plant based diet, and then you start eliminating estrogen and testosterone

[00:36:54] Carl Lanore: [00:36:54] B12 you'll increase increased copper, reduced [00:37:00] iron.

[00:37:01] Ronnie Milo: [00:37:01] Oh yeah. And then you'll start seeing a lot of injuries now in the gym, right?

[00:37:04] Carl Lanore: [00:37:04] Oh yeah.

[00:37:06] Ronnie Milo: [00:37:06] It's one of my ligament. I tore my tendon. You know why? Cause I'm on plant based diet. There you go. We just, we just uncovered this study showing that estrogen is important for ligament, tendon and bone repair.

[00:37:15] Carl Lanore: [00:37:15] Well, and, and to come full circle to something I said before, during Reaper, it's called reproductive fitness.

[00:37:21] The body will make adjustments for every stupid frigging disease idea you choose. They will, the body will keep you running until you get past that age. Where you should've reproduced by now, and it's time for you to clear up the proud. So when you have these, these bodies, these athletes today going, Oh, I'm a vegan athlete.

[00:37:43] How old are you? I'm 29 years old. I'm 32 years old. Okay, stay vegan until your forties watch what happens once your body gets past reproductive fitness age, it says, okay, you're an idiot. So we're just done with you. We're not, we're going to stop making adjustments for your bad [00:38:00] decisions.

[00:38:00] Ronnie Milo: [00:38:00] Right? Absolutely.

[00:38:02] Yeah, that's it. It's a, it's a trend right now. It's a trend. And, you know, unfortunately we're in the middle of that trend because we get all the people ask us questions, right. Cause they, they, you know, they understand and, and, and take our opinion and it's kinda like, no, we're not designed for that. You know what I mean?

[00:38:17] So we're, we're caught in the middle, uh, unfortunately. Right. You know, that's my position.

[00:38:22] Carl Lanore: [00:38:22] I want to talk, I want to talk briefly about the, uh. The role of a, I just saw a question come up from John peaks and let me just put these up real quick and then I'll come back.

[00:38:34] Ronnie Milo: [00:38:34] He's one of our guys

[00:38:35] Carl Lanore: [00:38:35] jumped in. Yeah, yeah, yeah.

[00:38:36] He says, uh, he says, Hey, Carl, Elaina and I are in Oklahoma, headed to Kansas city tonight. Then home to little rock for tomorrow. Wow. And thanks for watching live, John. There he is in his, in his seat of his truck. Right there. There you go. Oh yeah. Peanut PANORG said, um. They said, you can get B12 from the unwashed dirt from the vegetables and the [00:39:00] streams.

[00:39:00] You know, I don't necessarily doubt that there isn't B12 in the dirt. Um, I don't, I don't know. I, I don't want to, I don't think you can get enough B12. Yeah. From those sources because you're generally washing this stuff off, but there's so much more wrong with the diet. Even if, even if they're right about B12, I'll give it to them.

[00:39:21] There is so many other nutrient deficiencies, and we know that we have a, we have a predecessor call Australia . Robustness. It had big jaws, big gut, because it spent all its waking hours chewing food to try to extrapolate nutrition. And it was Australia pit because Africanas or grass seal, uh, which share the same name, uh, that, that started to eat meat.

[00:39:51] And then they went on. They actually outlived. The, uh, Australia, Pythagoras, a robustness by almost twice, [00:40:00] twice the lifespan. So that tells you something and, and their brains got bigger and their guts got smaller. Right.

[00:40:09] Ronnie Milo: [00:40:09] But, but look, but look at the, the food sources back in the day. Right now, they're being farmed at such a high rate that the nutrients and the minerals and stuff are going to be able to replenish in the soils.

[00:40:18] So you're barely getting any nutrients

[00:40:20] Carl Lanore: [00:40:20] at all. Yeah. I mean, I don't think you can get enough B12. From the, the scant amount that you're going to find in dirt, even if it, your body can absorb it. Um, but you know, it, it's just, it's stupid. It's just all so stupid. They recognize that you have to, you have to, uh, they recognize that you have to supplement with it.

[00:40:38] If you're a vegan, they know that. Right? Otherwise, I'll eat the dirt. If that works, eat the dirt, then.

[00:40:44] Ronnie Milo: [00:40:44] And we test for B12 on our, on our labs, and sometimes it comes back low and I'm like, do you take B complex be 12 I knew. I'm like, well, it's not working

[00:40:52] Carl Lanore: [00:40:52] well. So here's another reason, because there's something in the gut called intrinsic factor that if you don't have intrinsic factor in your gut, you can't absorb the [00:41:00] B12 that's entering through your mouth.

[00:41:02] That's why a lot of people turn to sublingual to try to bypass digestion because there's no intrinsic factor.

[00:41:08] Ronnie Milo: [00:41:08] And we do injectable beach wall and B complex, uh, at the clinic. Yeah. I take myself, honestly,

[00:41:13] Carl Lanore: [00:41:13] I actually am using a B complex right now. I'm just very surprised that it doesn't have more B vitamins in it.

[00:41:20] I

[00:41:20] Ronnie Milo: [00:41:20] don't think they could get that much in that

[00:41:22] Carl Lanore: [00:41:22] lounge. That's what it must be. They should make a double like one way you use this one and that one at the same time. I want to take a break and when we come back, I want to talk about cholesterol some more because there are a lot of women out there who may have.

[00:41:34] Been told by their doctors that their cholesterol is high and nothing they do seems to lower it, and I'm going to tell you why that is. When we come back, stay tuned, we'll be right back. Put myself back on the right side for a little while. Still learn how to use this new a platform. It's pretty cool.

[00:41:53] There's a lot of things I can do. I like the fact that I could put people's questions up and add them to the show and all that sort of stuff. It makes a big [00:42:00] difference.

[00:42:00] Ronnie Milo: [00:42:00] Came along late. Huh?

[00:42:02] Carl Lanore: [00:42:02] I don't know about that. I don't know if I've come a long way. I just, you know, I, I just try to make things a little bit better here and there, uh, as I go along, that's really all I end up doing.

[00:42:11] Yeah. I, so I want to talk for a minute about estrogen and cholesterol because this is something that men need to hear for their wives and the women in their lives and women need to hear as well.

[00:42:27] I know women over the past decade who have had high cholesterol and who would not on HRT, and they, they were upset. The doctor's putting them on Staten drugs. They know that Staten drugs have a risk. And I say to them, you know, cholesterol is a building block of all of the sex hormones. And if you're of a certain age and you're not.

[00:42:53] You know, doing well, your period is slowing down or you've stopped entirely and you're actually in menopause. Uh, [00:43:00] you should get on HRT for a variety of reasons, but one of them is that your cholesterol will normalize and people just can't believe this. They can't believe this, that they'll say to me, well, if that's true, why wouldn't my doctor have told me that?

[00:43:15] Well, maybe because. HRT isn't one of his quiver arrows in his quiver. So he doesn't want to open up the discussion with you. But I will guarantee you, and I saw this, I've seen this dozens of times, dozens, women who are not on HRT having high cholesterol get on HRT and their cholesterol becomes model. And you're like, why?

[00:43:39] Why? Because, because your body makes cholesterol to make hormones. And when you get older. That cholesterol is not being used to make hormones anymore. So it's almost like you continue to cut wood even though you don't have a fireplace anymore. And all of a sudden, one day, your yard is completely filled with wood because you're not burning any.

[00:44:00] [00:44:00] Once you get on HRT, you will see your cholesterol. I'm talking about within 60 days normalized because all of a sudden, if you are supplementing with testosterone, progesterone, uh, uh, uh. Extra dial bias after dial estriol, maybe some , maybe some pregnant alone. All of us all, all of a sudden, yeah. All of a sudden that that cholesterol is being used now, it's being used and it as a result of that.

[00:44:31] Your cholesterol has something to do now instead of just continue to float around your blood, and I know people are going to say, that doesn't make any sense. Caller. Okay, then try it. Give me find a woman who doesn't have, that's not on HRT and our doctors telling her her cholesterol is dangerously high and telling her, Oh, it's your genetics.

[00:44:46] You know, put her on HRT 60 days later. All of a sudden she doesn't need stat and drugs anymore. Right?

[00:44:54] Ronnie Milo: [00:44:54] And I, and I had this conversation probably 15 times a day, right? Cause we do labs, we look at [00:45:00] labs and we go over cholesterol obviously is one of the big thing is, uh, you know, total cholesterol, total cholesterol ratio, HDLs, LDLs.

[00:45:08] And then VLDL, right? So I always have this conversation. Now your body makes 3000 milligrams of cholesterol day, right? In your body. Your brain specifically is 50% cholesterol, 50% fat, okay. Also, it's responsible for your, to your point, sexual hormones. It's also responsible for cellular, uh, degradation and also passing through vitamins of the cell.

[00:45:32] It's got there kind of like the bouncer, right? They let the fat soluble vitamins in and out of the cell. Obviously, so cholesterol is very important for human function and a tenfold right now. People want to look at HDL and LDL, and I said, they're not cholesterol. They're proteins, and what they are is HDLs are the ability to bring cholesterol away from the liver.

[00:45:51] LDLs are the ability to do plain Crestrol to the liver.

[00:45:54] Carl Lanore: [00:45:54] Now, when

[00:45:54] Ronnie Milo: [00:45:54] we look at total cholesterol, they said, it's high. I said, to who standards. They said to the [00:46:00] standard of the labs, I said, that's a standard set by a lab company that's in cahoots with the pharmaceutical company that are setting standards very low.

[00:46:07] Carl Lanore: [00:46:07] I said, .

[00:46:09] Ronnie Milo: [00:46:09] 99% of the times cholesterol doesn't kill you. It's the oxidation of cholesterol. What I mean by that, if you put a banana on the counter, turns Brown, that's oxidation. If that happens intracellularly, then we can start to see cardiovascular problems with arthrosclerosis CVD or any kind of cardiovascular disease.

[00:46:25] Now, to look at that as the cholesterol ratio, right? Between HDLs, LDLs, and an L, looking at VLDL. Which is very low density lipids. Okay? Now, if they're very high, then there's a case that they could oxidize, and if the ratio is over 5.0 they could have a, a predisposition of oxidation, but 99% of time that people that we see their cholesterol, it could be two 50 total.

[00:46:47] They're not oxidizing. I said, you could live a healthy and happy lifestyle their entire life with that cholesterol because it's, you're not oxidized.

[00:46:56] Carl Lanore: [00:46:56] All right. And there are, there are even studies out there. Uh, there's two [00:47:00] studies from the university of Hawaii that are fantastic. They're actually called the Hawaii studies where they showed longitudinally that the people above 70 years old that had the highest cholesterol lived the longest.

[00:47:14] Exactly. That doesn't make, that doesn't make sense compared to, you know, what we talk about here on that, on the main Island, you know?

[00:47:21] Ronnie Milo: [00:47:21] Right. Is what they want to do is they want to set a standard and everybody has high cholesterol, so they want to put you on a Staton. And then once you start limiting, you know, cholesterol, then everything else starts to happen because you're now down-regulating sexual hormones and everything else.

[00:47:34] Carl Lanore: [00:47:34] I have a friend whose father was a very successful surgeon. I've talked about him before on this show, but if it fits nicely into the discussion, and he started taking Staten drugs 20 years ago, he didn't have high cholesterol, but. His doctor friend told him that if he started now, he would never have high cholesterol, so he wouldn't have to worry about ever developing plaque and his heart would be protected as he aged.

[00:48:01] [00:48:00] Well, of course. What's one of the well known side effects of longterm stat and drug use? Dementia, right? Yeah. He's in a nursing home today. Can't take care of himself anymore. And, and I actually told his son eight years ago, you know, he really should get off of those. They're not providing him with any.

[00:48:19] Longevity benefits. He's already, you know, in his seventies now. He's like, he needs to get off of those, and he won't get off of him. And he's still not off of him. He takes him religiously every single day in the nursing home. So the, you know, the whole Staten drug thing was a big boondoggle, and a lot of people.

[00:48:42] Got sick from them, they could develop, you know, one of the, one of the side effects of longterm stat and drug use is what type two diabetes. It makes you insulin resistant.

[00:48:50] Ronnie Milo: [00:48:50] Oh, absolutely.

[00:48:50] Carl Lanore: [00:48:50] So then it leads to Metformin and that leads to this and that leads the next thing you know, you're taking eight frigging pills because it is one.

[00:48:57] Now your doctor insisted you had to take it. [00:49:00] You want them to stay alive.

[00:49:01] Ronnie Milo: [00:49:01] And it's detrimental to your liver. It puts too much stress on the liver. And then here, here it comes full circle, right? They put somebody on Statens and down-regulate sexual hormones. What's the side effects from statins? Muscle cramping, joint pain.

[00:49:13] So there you go. There's

[00:49:14] Carl Lanore: [00:49:14] Abdo rhabdo for rapid brat, rapid breakdown of muscle tissue so quickly that it clogs up the kidneys. Yeah. Think about that.

[00:49:25] Ronnie Milo: [00:49:25] Yes. Not able to shelter out the creatine kinase.

[00:49:28] Carl Lanore: [00:49:28] Well, it's not just that, it's the, uh, I can't think of the name of it now, but I've done a show on rhabdo and it's actually something else that causes the Rab though.

[00:49:34] But the bottom line is the muscle breakdown is so rapid that the kidneys are just clogged up. They just can't handle all the debris coming down to them from taking statin drugs. Yeah.

[00:49:47] Ronnie Milo: [00:49:47] And my main objective is I get somebody on site. It doesn't get them off stuff. Basically. That's my objective.

[00:49:52] Carl Lanore: [00:49:52] I have a good friend that's been taken.

[00:49:54] It was taken him for years, and I finally got them to stop taking them. And he's a young guy. He's in his late thirties, early forties. So [00:50:00] I, so what's happened?

[00:50:02] Ronnie Milo: [00:50:02] No, probably. Thank you for that

[00:50:03] Carl Lanore: [00:50:03] someday. Um, so in summary, uh, we know that women develop. Tendon and ligament issues after they've gone through menopause.

[00:50:15] We know that women tend to develop osteoarthritis after they've gone through menopause, and we also know that when you go through menopause, there is a sensation of the production of estradiol and estriol and not as strong. So as strong goes up when after women go through menopause. In fact, as Strohn is known as the old lady hormone.

[00:50:39] Yeah. And it's more closely tied to, um, unique types of cancers, then Esther dial is, believe it or not,

[00:50:48] Ronnie Milo: [00:50:48] cause it's compensating. That's why, yes. Compensating from the decrease in estrogen, Astro or the extra dial on the estriol.

[00:50:54] Carl Lanore: [00:50:54] Right, right. Yeah. So, you know, we know that, uh, we know that. [00:51:00] These onset of injuries happen at a higher rate when estradiol and estriol and estrone are being suppressed through menopause.

[00:51:09] We also can assume that men already have very low estrogen levels. Now as they get older, their testosterone tanks, and there's more of a siphoned off through aromatase into estradiol. It would be interesting to find out if that protects their ligaments and tendons. Well,

[00:51:28] Ronnie Milo: [00:51:28] also too, if you see that somebody has a low testosterone or that it's just to compensate, they have higher estrogen aisle, they'll carry more body fat.

[00:51:35] Right. Because there's the robotize inhibitor or the rheumatologist. Um, you know, receptors on

[00:51:39] Carl Lanore: [00:51:39] what's the, I think it's the other way around. I think so. I think that though, I think that resting metabolism shifts, they move less. They still eat the same amount, and as they accumulate body fat. More of their testosterone is siphoned off to dial because, because [00:52:00] then they're not, they're not making body fat because they don't need us to dial like women see women.

[00:52:06] It's a different story. Women's bodies will actually start to manufacturer fat as they lose their ovarian function to make up for the estrogen that they're losing. So they'll actually manufacture fat for the aromatase inhibitor, aromatase enzyme that lives in the fat cells, but men don't need us to dial.

[00:52:28] I think it's the flip side with men and my own opinion, no proof. I think men get fat. First, and as they get fatter, their testosterone drops through us to dial stuff to come up. Right.

[00:52:40] Ronnie Milo: [00:52:40] And I see that a lot in the blood work too. Cause you know, I remember I don't, I don't see a lot of patients, right. I could just tell them through their blood work and if I see that their testosterone is low, their Astra dials high.

[00:52:49] I said, I said, don't take this the wrong way. Are you overweight? And they said, well, yeah. How do you know? I said, well, I could see it from the blood work because your estrogen, your estrogen Isles is elevated. Right, right. All right. So,

[00:53:00] [00:52:59] Carl Lanore: [00:52:59] uh, keep your estrogen levels in check. Make sure that you have estrogen, if you're a man or a woman, make sure if you're a woman, it's the right levels and from man as well.

[00:53:10] Uh, but don't think that estrogen is not playing a role, uh, in formation and DNA transcription, uh, of soft tissue repair and reconstruction. It's a critical player, critical player, and we have a lot of women out there who are taking all sorts of. Cosmetic stuff. Oh, this will improve collagen production.

[00:53:31] Yeah. You know, to improve collagen production, get your estrogen levels back up, and you'll have, you'll have the most beautiful skin in the world

[00:53:38] Ronnie Milo: [00:53:38] and don't overdo the AIS. I see that all the time.

[00:53:41] Carl Lanore: [00:53:41] You know, I've never, I've never had a problem. I'm not a high aromatase zer even at really, really high doses of aromatase usable androgens, my extra dial has never gone over.

[00:53:51] Maybe 60 which was not a big deal considering I was using two grams of tests. Right, right. Yeah. I've never had [00:54:00] gotten, you know, sore nipples or tendon nipples. I've never gotten any signs of that at all. So I've luckily stayed away from aromatase inhibitors because when I do take, if I take a half a milligram of anastrozole, I don't sleep good that night.

[00:54:12] Ronnie Milo: [00:54:12] Yeah, you and me. I don't use them at all. I'm the same way. If I do take it, I, I feel weird. I feel like hot flashes

[00:54:18] Carl Lanore: [00:54:18] and sleep. Yeah. I don't, I don't have that high of estrogen to begin with, so I'm suppressing it is probably a stupid idea for me. Well, I mean, everybody's different.

[00:54:27] Ronnie Milo: [00:54:27] Some people can function at 60 you know, Nana grabs a Delta leader for the estrogen without a rheumatology.

[00:54:32] Right. Some people get to, you know, 20 grand, 20 nanograms per deciliter, and aromatase. So everybody,

[00:54:38] Carl Lanore: [00:54:38] but you know why I know why I, I'm not a high aromatase. Of course, I'm an extremely high five alpha reducer. Right. And DHT suppresses aromatization. Exactly. Cause my, my, when I, when I use high doses of androgens, aromatase double androgens, my DHT is what goes up along with my testosterone.

[00:54:57] Right. Stupid level.

[00:54:59] Ronnie Milo: [00:54:59] And you [00:55:00] can, and you could use the DHT. Me, I can't look at my hair, you know what I mean? I'm, I'm a high aroma Tiser for DHT. So there, there it goes.

[00:55:09] Carl Lanore: [00:55:09] All right, we're going to pull the plug on the interview today. Uh, it's been good. And, uh, I probably won't see you before. So bono, Nepali, Merry Christmas to you.

[00:55:19] And so I'm off the air tomorrow. Let's see. What is Christmas? Christmas is a Tuesday.

[00:55:24] Ronnie Milo: [00:55:24] Yeah, next Tuesday. Lunch. Christmas Eve. So I think it's Wednesday.

[00:55:27] Carl Lanore: [00:55:27] Um, I believe I have a show on Monday. I don't think I have a show on Tuesday. I'll have to see what I set up for the week because the holiday is here and I wish everybody a Merry Christmas.

[00:55:37] Uh, and, uh, of course, uh, happy Hanukkah has already passed, so I apologize for that. For my Jewish listeners and, uh, and all of you, whatever holiday you're celebrating a hope, it's a wonderful one with your family. Uh, don't eat too much. If you're going to eat a lot, do the same thing we talked about on Thanksgiving.

[00:55:54] Bust out, you know, 40 or 50 67 you know, two or three [00:56:00] sets of 20 pushups before you sit down and eat to turn on the muscle making machinery. And who knows, you may come away instead of having more fat, having more muscle from this holiday seasons.

[00:56:09] Ronnie Milo: [00:56:09] Right.

[00:56:11] Carl Lanore: [00:56:11] All right, so we'll see everybody next week. I think I will be on the air Monday.

[00:56:15] If not, I will let you guys know. Thanks for listening today. Pass the show around. Share the show. We need you to share the show [00:57:00] .