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Transcript to SHR # 2634 :: The BluePrint Power Hour + How Glyphosate Produces Transgenerational Epigenetic Disease

[00:00:00] Carl Lanore: [00:00:00] Welcome back to another episode of super human radio. Today is December 15th, 2020. The year is coming to an end. Many of us are going to be happy to see this year ago. Um, but who knows, maybe this will be better than next year. And we'll be looking at this as a fondly, uh, the year we wanted to continue living in.

[00:00:18] I doubt that very much, but anyway, we have a great show for you today. Of course, today is Tuesday, so we have the blueprint power hour. Uh, coach Robin. I asked her as answer your questions. Uh, none of the questions are off topic. We like to talk about training, nutrition, drugs, uh, uh, um, supplements, things like that, but people ask us questions, uh, quite diverse, uh, sometimes, uh, much broader than those topics.

[00:00:46] So feel free to do that. And the place to do it is right here, uh, on Facebook or YouTube where you are watching live. Uh, I'm actually unlocking YouTube. I found out later [00:01:00] this week that unless I go to YouTube and switch the primary link back to public, instead of friends only, I don't see a lot of the comments that people make.

[00:01:12] So we'll be able to see all of your comments today doing it right now. Um, Before we get started. Of course I have to thank our title sponsor. And that is legendary foods. Uh, the website is SHR network.biz/legendary. The code is SHR 10 to save 10% off everything there. They have such great stuff. If you haven't been like, if you've been listening to me, say this at the beginning of every show.

[00:01:39] But you just don't think it's interesting to you. You have to go to Legendary's website, SHR network.biz/legendary. They have seasoned almonds that are the best in the world. And I'll tell you why they're the best because they almonds are the freshest. One thing about Ron Penna. Uh, and we learned this from quest.

[00:02:00] [00:02:00] He is a stickler when it comes to raw materials and he only gets the best. And in this case here, he gets the best. Uh, almonds you've ever had that you, they taste like almonds. So many amens don't even taste like almonds anymore. And then Shannon Penna comes up with these amazing, uh, blends of spices and seasonings that she puts on them.

[00:02:22] Uh, they're they're seasoned almonds are own believable. They're nut butters are unbelievable and no sugar in there, nut butters. And of course, uh, Snack. That's taking the world by supply surprises. They're tasty pastry, which is basically a Pop-Tart with zero sugar. In the case of the two new flavors, blueberry and hot fudge sundae, 15 grams of high leucine protein.

[00:02:45] Um, no gluten and. Not a ton of fiber. I I've grown so tired of too much fiber in snack foods. Um, and I think a lot of people are [00:03:00] starting to notice that as well. Uh, go-to SHR network.biz/legendary use the code SHR 10, not only to save 10% off on some of the best snacks she'll ever have, but also to let them know that you heard about them here on superhuman radio.

[00:03:16] And without further delay, let's line up Rob's music here and play that calling all

[00:03:23] Coach Rob Regish: [00:03:23] blueprint army

[00:03:24] Carl Lanore: [00:03:24] fall in line. It's time for the blueprint power hour

[00:03:28] Coach Rob Regish: [00:03:28] with coach

[00:03:29] Carl Lanore: [00:03:29] Rodriguez on the superhuman radio network.

[00:03:35] how you doing Rob?

[00:03:37] Coach Rob Regish: [00:03:37] I'm doing well, although I'm fucking awful cold. It is 35 degrees here in wonderful Massachusetts. And it's just going to get colder. I guess we've got a storm on the way, but we'll see.

[00:03:49] Carl Lanore: [00:03:49] Yeah. New York is getting hit with it already down to downstate New York. So what that means it's on your radar too.

[00:03:55] And interestingly enough, this morning, it was 24 degrees here in Louisville.

[00:03:59] Coach Rob Regish: [00:03:59] Oh, [00:04:00] wow. Wow.

[00:04:03] Carl Lanore: [00:04:03] Really good conversation with a good friend of mine. We both ride. And I said, when I was in New York and in college, I was living in South ozone park Queens. I was going to school downtown Brooklyn at the city university of New York.

[00:04:17] And, uh, there were days where it was the middle of winter, December, January, February, and we had had snow, but the snowplows came through the streets and. Cleared the snow away and the main thoroughfares like Atlantic Avenue in the highways, they were, they were just fine. They would dry by the morning jet.

[00:04:37] Typically from the road of being dried by cars. I would ride my motorcycle to school because I didn't have a car and I didn't want to take the train. And I remember that, uh, I used to have to cover my face with a bandana. Because the hair in my nose would freeze every time I inhaled and tears, I just wore sunglasses.

[00:04:58] Tears would run [00:05:00] down the sides of my eyes in, towards my ears and freeze into little icicles on my face. And I said to my buddy, Billy, I said, you know, I have a rule now, 48 degrees or more I'll ride. But back then, I didn't even pay it to, I didn't even check the weather. I just knew the streets were rideable and I would go out and I'm sure I was riding in 25 and 30 degree weather back then.

[00:05:24] Coach Rob Regish: [00:05:24] Did you see anyone else riding a motorcycle? No. No.

[00:05:29] Carl Lanore: [00:05:29] And I'm sure,

[00:05:31] Coach Rob Regish: [00:05:31] I'm sure you didn't have a car.

[00:05:33] Carl Lanore: [00:05:33] Yeah, I didn't. And I didn't want to take the eight train because it was, it took me literally 20 minutes real time to get to school on my bike versus an hour and a half on the, a train.

[00:05:43] Coach Rob Regish: [00:05:43] Yeah. So

[00:05:45] Carl Lanore: [00:05:45] anybody we have, uh, we have some exciting news about the blueprint Bolton, right?

[00:05:48] You got, you still have something

[00:05:49] Coach Rob Regish: [00:05:49] going on, uh, and look, being, being the time of year that it is, um, why not give yourself something that you really want instead of depending upon folks and [00:06:00] perhaps not getting, uh, something that you really want. I'm talking about the blueprint bull and, you know, people ask me all the time.

[00:06:06] They say, Hey, I love. The blueprint power hour. What is the blueprint bulletin? And I tell them, uh, it's everything we discussed here on the show plus, right. I got to save the absolute best stuff and I do for my subscribers, but people of course are, you know, they're skeptical. Um, money's tight. It's been tough out there.

[00:06:25] That's no secret. So, uh, what we are doing is this, we have a special now, uh, where for less. Then $5 a month, you can get the first three months over the blueprint bullet for just four 99 a month. Uh, which is an incredible deal full 90 days to check it out. You also get instant access to the entire library.

[00:06:50] All right. So we're talking over a hundred issues now, uh, in addition to that new issue, you'll be getting every month and you get two freebies here. Um, one [00:07:00] is the fast fat loss report, which is, it looks this time of year. It's no secret. A lot of people's struggle, right. With putting pounds on. This is a really interesting.

[00:07:10] A little report that will clue you in, on both the stimulant and the non-stimulant fat burners out there and where to find them, which is an interesting in and of itself. And then finally, if, if even before buying, if you want to check this out, uh, we are giving you a free sample issue so that you can see for yourself.

[00:07:32] Uh, what I put into this, what the blueprint bulletin is like and what kind of value you will receive in exchange for that real pittance of a, of a price. So, um, now we have a special URL,

[00:07:47] Carl Lanore: [00:07:47] right? Yeah. The URL is SHR network.biz/coach Rob. And once you're there, they argue the code SHR five. The code is also on the top of the page.

[00:07:57] So you can't forget it. And you pay for all three [00:08:00] months and in one shot, you pay 1499 and you have access to it for three months, possibly three, the most important ones to have access to this, because let's be honest, I'm living proof. I haven't trained in three weeks and it's not because of the holidays.

[00:08:15] It's because the move and my gym and the COVID so doubling down on information that could help you. If not. Gain muscle and lose fat, not gain any fat and lose muscle during this next 30 to 60 days. This is gold. This is gold for 1499 and get three months of it.

[00:08:39] Coach Rob Regish: [00:08:39] And I I'm really excited about, um, next month's issue.

[00:08:42] I'll be debuting a new training system that I think is, uh, it's motivating me to get in the gym and do my thing because of the results that I'm seeing. And I know, I know when people see this, they're going to love it, where they, whether they choose to do it right in [00:09:00] by itself. Or use a little bit of it, uh, to sprinkle in their training, to, uh, to jazz things up, which frankly is something we all need every so often.

[00:09:10] Carl Lanore: [00:09:10] Yeah, I agree. Okay. Let's get to the first question. The first question, hold on, let me just scan up here. And the first question comes from Mike Graham. He says, uh, I'm do, I'm going to use equity sterile and soon, but wanted to know the best kind to get. Let's say I wanted equity by itself. I've thought of this too, just buying raw powder other than , which herbs should I be looking for?

[00:09:35] Coach Rob Regish: [00:09:35] It's a popular question. It's one. I get a lot, you know, if I want to get back to you just by itself, what should I be looking for? So, um, Most people are familiar with the fact that I prefer and recommend full spectrum repotted com. The reality is that there are a small handful of other plants that contain enough equity to make them [00:10:00] worthwhile.

[00:10:00] And so these range. From herbs grown in Russia to Bulgaria, to, to South America, uh, and elsewhere now much depends. However, whichever one you choose much depends on which  that you are looking for or whether you want the full spectrum stuff that I talk about. So often. If, for example, you're looking for 20 hydroxy acne sterile that can be extracted from a number of sources, everything from the quality stuff, which I.

[00:10:35] You know, respond to come is what I, what I recommend, but you're also going to see it derived from sign notice, spa sign, notice a rachnoids uh, there's another sign notice source genus that frankly, it's just, it's not recommended. There are no human studies. There are no studies period behind signed notice and something else that I learned about sign notice recently, uh, there are no toxicological studies on it.

[00:11:00] [00:11:00] So, whereas we have that data on many other plants showing incredible safety with respect to the  content and the rest of it that doesn't exist inside. I notice. So I, up until recently, I didn't know that. Um, but it's just another black Mark right on sign notice and, and check D from such. Yeah. Other plants, uh, uh, jugar tourist.

[00:11:27] Turkistan Leica is a good one and believe it or not something called Vitex. There are several strains of Vitex, which is traditionally marketed towards women and, uh, you know, PMs relief. They actually contain some acne steroids. Uh, now. Equity is also pregnant. You might see this in the market, uh, in fund G various strains of fungi.

[00:11:53] Oh, I've only seen one company that sources equity from fungi. Uh it's [00:12:00] it's not have a good proposition. In my opinion, I have seen much like, yeah, the research isn't there. Like it is on other plants. If you're looking for Turkey, Westeros, It is naturally present and , but not in really commercially viable amounts for that.

[00:12:20] You want a jugar Turkistan Anika. Okay. If you want to her, that's where to get it. Brazilian Suma is also an acceptable plant source, uh, and it all, it includes rare things. Cranium, which has in some studies been shown to regenerate tissues along with, uh, believe it or not several amino acids and other beneficial compounds.

[00:12:46] It is naturally Minich and keenwah. Although the eat a lot of both, right. To get a, to get enough, unfortunately, on the Summa quality soup [00:13:00] is very rare, right? There are a ton of five to one junk extracts that you're going to find out there that don't do anything. There is one 25 to one Summa. Extract on the market and its trade name is ultra Suma.

[00:13:14] If you can find that, especially in isolation, by all means, grab it. It's good stuff. Otherwise I still stand by the  right, uh, recommendation more and more. I am convinced that that is due to several of the  in not just one, uh, that have these. Pretty powerful lowering of blood sugar effects and anyone that's used enough of that good reposit gum, 500 milligrams a day or more, and they've got blood work done, right.

[00:13:51] That looking at fasting blood sugars, they're going to tell you the same thing. I have had a dozen guys. In the last year, [00:14:00] email me and say, Hey, you know, I heard you talking about that. And I got on the XYZ product and sure enough, man, my, my blood sugars are, you know, 20, 30 points, lower 2030 points is huge.

[00:14:11] And, and I see that

[00:14:14] Carl Lanore: [00:14:14] Metformin does that,

[00:14:16] Coach Rob Regish: [00:14:16] that 20, 30 point drop is something that I see too. I didn't know if I was an anomaly, I guess I'm not because these other guys tell me about it. Um, and, and that's important. Why is it important? Well, not just from a general health perspective, right? Lower blood sugar.

[00:14:34] But when we look at fat loss, Right. Especially this time of year, we're looking for things that are going to help us. Well, we hear a lot about thermogenics. We hear a lot about, you know, uh, stimulants. We hear a lot about even some non-stimulants and appetite suppressants, yada, yada, but the, the tie that binds in every FA successful fat loss study that I've [00:15:00] seen, whether it's low carb, low protein, low calories, or what have you.

[00:15:04] Is low blood sugar and consequently, low to steady insulin levels. Yep. Personally, I think, uh, I'm, I've been looking at a couple of different combinations of equity steroids to see if they lower blood sugar better than just the full spectrum of ponticum or this or that ID. I have some promising data around that, and I'll tell you this one way or another.

[00:15:31] It's going to make it into my next product, which will be a female fat burner, right. Fat burner for women. Now that doesn't mean it won't work in men, but it is being designed and will be marketed more so to, to the fairs. Yeah. Cause

[00:15:51] Carl Lanore: [00:15:51] they're the ones that step on the scale every day. And they're the ones that go.

[00:15:54] I'm never going to eat again. The scale is up a half a pound. Yeah.

[00:16:00] [00:16:00] Coach Rob Regish: [00:16:00] Yeah. It's, it's interesting because, um, you know, I talked to some of Jen's friends, I talked to women in the gym and it's just, like you said, you know, uh, even none of them sleep. Right. Which is another question I asked them, but just to illustrate the, the mentality, I had more than one, tell me.

[00:16:21] If I have to go sleepless, I'd rather lose eyebrows, brother. See the pounds on the scale, go down first, you know, without even getting a good night's sleep. So if, if they're going to choose between the two, that's what they do. So why not go on that direction?

[00:16:37] Carl Lanore: [00:16:37] Right. I think it's funny when, uh, When men talk about, Oh, I'm, I'm up two pounds and women are like, I don't understand why you're excited.

[00:16:45] Oh no, probably muscle. At least some of it's muscle. It's like, yeah. But why are you excited? Yeah. Dave Hartnett posted this. When we, when I was talking about the, um, Uh, legendary foods, um, tasty pastries. He, those blueberry ones are amazing. [00:17:00] My issue is I ate the whole box in one city, David Italian. We would call you a govern and I would call you my gov own brother, because I do the same thing.

[00:17:12] I can't keep this stuff in the house Elisa, so good. Elisa will have one. And then later on in the evening, I'll say, Hey, you want to tasty pastry? And she'll say, no, I already had one today. I'm like, what? So you can't know

[00:17:27] Coach Rob Regish: [00:17:27] how many are there to a box?

[00:17:29] Carl Lanore: [00:17:29] I think it's 10. I'm not sure. I think it's 10. It's a considerable number.

[00:17:33] It's not like five.

[00:17:35] Coach Rob Regish: [00:17:35] Yeah, no, that's, that's cool.

[00:17:37] Carl Lanore: [00:17:37] Yeah. I'm the same way. I'm a Gabo. When I eat, I eat it until it's gone. That's how, that's how I decide when to stop when there's no more to eat. All right. The next question comes from Alex, right? He says, what do you make of super slow training? I saw once using it in the gym, someone using it in the gym the other day and weathered wondered whether it was worth trying.

[00:18:00] [00:18:00] Coach Rob Regish: [00:18:00] Yeah. Well, super slow really brings up. Um, the issue is really this right, uh, rep tempo, how quickly or slowly that you move the weight and associated time under attachment. And from what I've can seen, have seen from being in this game for many years is manipulating either one of those has gone in and out of style several times over the last 30 years or so.

[00:18:30] Carl Lanore: [00:18:30] And I've never, I've never seen anyone except maybe Joshua Trentino who's built significant muscle continuously on, on a super slow program.

[00:18:45] Coach Rob Regish: [00:18:45] Yeah. And, and that's believe it or not. That's part of my answer because, um, when it, uh, was really popularized back in the nineties, I actually did it, but I'll get there in a second.

[00:18:59] But [00:19:00] what we're talking about here is for most super slow protocols, most of them are talking about. Slowing the negative part, part of the movement down, um, but super slow in its strictest interpretation, advocated, both the positive and the negative as being super slow. Now, I can't recall the exact name, but there was a book written in the early to mid nineties advocating the super slow philosophy.

[00:19:30] I bought it. I read it. Parts of it made sense to me. So of course I tried it and if I recall correctly, I did so for about four months. And I want to say I was using a six second negative as well as the six, second positive.

[00:19:48] Carl Lanore: [00:19:48] And so that's low.

[00:19:50] Coach Rob Regish: [00:19:50] Yeah. So here are the things I remember, number one, you need to obviously to drastically lower the amount of weight that you were working with.

[00:19:59] Number [00:20:00] two. Was that I was some of the most painful training I have ever done in that the burn during those reps was excruciating. I think it was the positive portion that was worse than negative. Um, number three was that I didn't grow any faster. And that number four upon resuming the classical barbell lifts bench, squat, deadlift, I was dramatically weaker.

[00:20:27] Now as with all training methods, there's a kernel of truth in super slow. So it is true. For example, that time under tensions have anywhere from 40 to 60 seconds seemed to favor. I think more so, more so than these, you know, very short duration sets, but think about it. You can get there. In far better way.

[00:20:52] So here's what I'm talking about. If you perform a four to five second negative, but then you lift the weight as [00:21:00] fast as possible in the, in the concentric. And one to two seconds that gives you roughly the same six seconds under tension, but instead of teaching your central nervous system to be slow, you're training your training.

[00:21:16] System and muscles to be fast and explosive the slope on centric, by the way, coupled with the dramatically lower tension that was on the bar, likely explains why my big lifts tanked so fast when I returned to them, I couldn't believe. How much weaker I was. I really couldn't. It may also explain why it didn't grow any better.

[00:21:38] Right. Despite the fact that my time under tension was greater, uh, with super slow, finally, consider this right. Just put our critical thinking caps on, as you like to say, the guys at West side Barbeau. They lift insane amounts of weight and whether it's the max effort method or the dynamic effort method, their muscles, [00:22:00] aren't under tension for a long, long time, right seconds.

[00:22:04] And they damn sure don't train to be slow in quite the opposite, in fact, right. Explosive dynamic effort days or speed. Last time I checked those boys were sporting plenty of muscle and strength, more than most bodybuilders. So here's the bottom line. If you take anything from super slow tech, a few seconds onto your eccentrics, maybe if you shoot for a five second negative, most people will count fast, frankly, and wind up at three seconds, which is.

[00:22:37] About right. In my opinion, in so far as the best compromise between strength in the hypertrophy bottom line, I didn't grow any better. And I got a lot weaker and it was just a real, it left a real bad taste in my mouth.

[00:22:53] Carl Lanore: [00:22:53] Do you think that there's a place for it once in a while, you know, like to throw it in here and there,

[00:23:00] [00:23:00] Coach Rob Regish: [00:23:00] maybe in people that are rehabbing an injury, you know, I, otherwise, I just can't.

[00:23:07] I, I just can't see where, where the benefits are and they're dramatic. Number of negatives, too many in my book to repeat that.

[00:23:17] Carl Lanore: [00:23:17] Well, later in the show, if you can stick around to the top of the hour at 2:00 PM Eastern, we're going to be interviewing a doctor who he's discovered through a study. Um, from Washington state, the great land grant university, Washington state university.

[00:23:35] They do a lot of work there when it comes to agricultural implications, they just provided, they show in a study that exposure to glyphosate changes, men's sperm that causes trans-generational epigenetic diseases. So we're talking about your children, your children's children, their children, they're all five generations deep.

[00:23:58] You know, [00:24:00] we've been told for years that glyphosate is safe by all of the talking heads out there that are on the payroll. Well, it's not only not safe, but your exposure to it now has implications to future generations. And they're going to use that to predict disease States. So, is it a happy ending to the story, but it's not a happy ending for the people who end up with the diseases.

[00:24:23] Ken Jukin says, I keep hearing the term feed efficiency thrown around what is it? And is it anything worth pursuing?

[00:24:35] Coach Rob Regish: [00:24:35] Yeah. The term deficiency and bodybuilding usually refers to more of the calories you eat being steered. If you will, toward muscle and away from fat, uh, Nutrient the term nutrient partitioning became a very powerful marketing term.

[00:24:53] Although at the time, if you understood what it really meant, it was used. If you'll recall to great effect, [00:25:00] um, like bill Phillips and Dr. Scott Connolly back in the mid nineties, when metrics was, was all the rage. Uh, but the term feed efficiency. Does show up elsewhere, such as veterinary medicine. Uh, and there, you can find, it mentioned frequently when discussing experiments that were or studies done in livestock.

[00:25:26] Right? For example, that's where I found, frankly, TMG trimethylglycine. You can go back. Uh, this was 1990. Seven 1998. Uh, when I started beginning to experiment with TMG and for the simple reason, I had seen several veterinary studies showing that it improved feed the F what they called feed efficiency. So think about it.

[00:25:53] If you're a farmer or you're raising cattle, if you can get an animal to grow on, [00:26:00] I don't know, 6,000 calories today instead of 10. And, and be leaner when it gets to market and therefore you can command a greater price. You've just saved yourself and made yourself a ton of money. So that's where feed efficiency will show up, uh, another case in point anabolics where the original and probably ultimate feed efficiency compounds.

[00:26:27] Uh, prior to even that though, if we think about it, Vince Gerardo. Noted, uh, that more calories could be eaten without getting fat when people eliminate the carbohydrates from their diet and instead ate fats and proteins. So understand that whether it's manipulating food, whether you're adding a powerful drug like DBL or you're just rearranging macros or using supplements.

[00:26:55] Yeah. Feed efficiency, I do think is a real, [00:27:00] uh, I'm going to give you one of the best right now, though, and it's absolutely free increasing your feed efficiency, sprints, get yourself onto the track twice a week and perform some sprints at top speed. And you're going to see exactly what I'm talking about on the same food.

[00:27:21] Your waistline's can be a lot. Trimmer. Sprints are quite likely the best training that you can do. I think too. Maximize every morsel of food that crosses your lips and spreads, physiques are proof positive. One thing is true. You can see you, you can find bodybuilders. Yes. That are extremely lean after a 16 week diet.

[00:27:45] But the rest of the year, they're not so lean. You're never going to find a out of shape sprinter or a fat sprinter. They just don't test. Or, or they don't cut it. I mean, you're either lean. Strong and [00:28:00] fast or your career in sprinting is over, you know, find something else to do. So watch any sprinter and how they train, uh, speaking of how they train, it's not just sprinting some of the best perform heavy squats immediately prior to their race.

[00:28:20] Uh, and then they sprint faster and faster likely why? Because of central nervous system excitation. You know, it's like putting a donut on a baseball bat, right. Swinging 10 times, and then taking it off. You'll be a lot faster and a lot more powerful when that donut comes off. And these are not okay.

[00:28:39] Sprinters. These are not fat people, right? Nor are they wispy though, like marathon runner. And they look like that because they're training steers more of their calories towards muscle and away from fat or burns the existing body fat stores more efficiently. So yeah, feed efficiency is a real [00:29:00] phenomenon.

[00:29:01] Um, but it's my opinion that the right training and the right macros are almost certainly the most powerful way to maximize. Every morsel of food that you eat, steer it towards as much towards muscle in a way towards fat. You know, it's always, it's always a combination of the fundamentals. It's never, you know what, just going to eat like crap.

[00:29:27] I'll try and haphazardly take TMG. No, that's not gonna work. But that's feed efficiency.

[00:29:35] Carl Lanore: [00:29:35] Tell you something else. This is something I like to call protein efficiency, proteins, certain proteins are better digested and assimilated than others, dairy and egg and King of the Hill.

[00:29:45] Coach Rob Regish: [00:29:45] Yes.

[00:29:46] Carl Lanore: [00:29:46] Soy sucks. P protein is okay.

[00:29:50] Soy protein is terrible because you, you, your body is actually designed not to absorb the soy protein because soy contains. A [00:30:00] trypsin inhibitor and trypsin is the enzyme your body has to make to digest soy proteins. Why people get gassy when they eat a lot of soy protein, it's digesting in your colon.

[00:30:11] Uh, but when it comes to protein, efficiency, egg and dairy King of the Hill, uh, even better than beef and chicken.

[00:30:20] Coach Rob Regish: [00:30:20] Right. So, whereas soy is, what's a biological value of 74, a whole egg is a hundred, right. That's feed efficiency. Do you want to eat 30%, right? 30% more soy just to get the same nitrogen retention is yeah.

[00:30:38] No,

[00:30:39] Carl Lanore: [00:30:39] we got a break. When we come back, we have a question about Doug Bernoulli's training from Robert Thompson. And I don't know if you're familiar with it. We just did a show with Doug. He's a phenomenal guy. Stay tuned. We'll be right back with more of the blueprint power hour.

[00:30:51] Coach Rob Regish: [00:30:51] This is the superhuman channel

[00:30:53] Carl Lanore: [00:30:53] where we use

[00:30:54] Coach Rob Regish: [00:30:54] oxygen for the power of good.

[00:30:57] Carl Lanore: [00:30:57] I had my microphone open during the break. I'm sure everybody [00:31:00] heard me laughing. Ben Greenfield just sent me the best. Happy anniversary video. We'll play it on the show Friday. Um, but he he's a pisser. I love the guy. He's really great. Uh, anyway, uh, let's go back and answer a question from somebody in the audience and that is Robert Thompson.

[00:31:16] He says, um, what are your thoughts on, uh, Doug Brignoli  training is skewing compound exercises for strictly isolation movements.

[00:31:28] Coach Rob Regish: [00:31:28] You want me to go first? Yeah, of course. Um, I'll admit, this is the first time I've heard his name. Uh, and I'm not familiar with, with what he's basing this on. It does look like from the little bit that I Googled during the break that he's put a lot of thought into it and I'll reserve judgment until I, I hear him on your episode.

[00:31:53] Um, I can only give you the benefit of my experience and, and. With compound versus [00:32:00] isolate isolation exercises. I never put any substantial muscle on with isolation work. I put a lot on with calm, big compound, heavy lifts, and with the exception of one, uh, arthritic right elbow, which may be because of baseball, you know, 35 years later, I don't have any substantial really injuries.

[00:32:26] Um, now. Can you work a muscle efficiently with an isolation exercise? Well, a lot of that depends, depends. I think on what the exercise is, what, where the lever arm is, uh, how much tension you can or can't generate, you know, with that muscle. But I wouldn't be surprised to hear from. Basically anyone that came to me and [00:33:00] said, you know what?

[00:33:01] I built my body, all this muscle with isolation, only exercises. And maybe that's not his argument. I don't know. Maybe he just thinks there's more of a place for isolation work. Um, but until I hear his entire spiel, uh, I'll reserve judgment.

[00:33:22] Carl Lanore: [00:33:22] So. It comes down to what are you trying to achieve? Can you, first of all, if you're lean,

[00:33:33] Coach Rob Regish: [00:33:33] you look bigger, this is a fact.

[00:33:36] Carl Lanore: [00:33:36] And if your goal is to be lean and as muscular as you possibly can without actually having to risk injury or work. Hard then Doug bronchiole has a really good training style [00:34:00] for you because you can achieve maximum, uh, muscle activation with using lightweight, but you're never going to be a mass monster.

[00:34:11] You're not you can't

[00:34:14] Coach Rob Regish: [00:34:14] because that's probably why my opinion is what it is

[00:34:17] Carl Lanore: [00:34:17] now. Well, I mean like, like Doug bronchiole has got a great training style of you're somebody who's achieved the level of physique that you enjoy and you just want to maintain it. You're not really looking to put on more. He's got the way to do it because you can get in and out of the gym and still have energy.

[00:34:38] Uh, he, he manipulates angles and he manipulates geometry and he manipulates things to hit the muscle to its fullest and its full range.

[00:34:48] Coach Rob Regish: [00:34:48] Yeah.

[00:34:49] Carl Lanore: [00:34:49] But you're never going to see somebody train a Doug bronchiole style training and then go compete, you know, in the bench, press deadlift and squat because that.

[00:35:00] [00:35:00] Muscle activation while your muscles will get stronger. I don't want people to say, Oh no, you can get strong. No, you can get stronger, but they're never going to work in unison the way you want them to work. Let's say to squat 600 pounds. Right. So, you know, it just depends on your goals. If your goals are.

[00:35:20] To have a big bench, a big squat and a big deadlift. You must train those moves because your S your, your central nervous system and peripheral nervous system must learn how to execute that move. You can't do it in pieces. You can't make your quad strong, your glutes, strong, all doing different types of things.

[00:35:37] You know, I'll give you a for instance, I had two daughters that were highly into figure skating, very expensive sport. And we, we actually had some of the best Olympic trainers in there. Um, and, uh, one of them, I can't remember his name now, but he worked with the, uh, Olympic skater [00:36:00] blonde head girl. And, uh, I sat down with him, Terry, his name was Terry something, Terry something.

[00:36:06] And he, he. Subscribed to teaching a skater, to do an axle by learning, to execute the three portions of the axle, the takeoff, the spin, the land. But he said to me, I can get you to do the perfect takeoff, the perfect spin and the perfect land in isolation. And you'll never do an axle until I teach you how to thread them all together in a continuum.

[00:36:38] And this is kind of what I'm talking about. When we talk about training and, you know, body, there's a lot of bodybuilders that move heavyweight with isolation movements and their muscles respond that way, but they may actually be putting themselves at greater risk of injury because they could tear a bicep.

[00:36:54] You know, you start getting too heavy, these smaller muscle groups, Doug doesn't espouse that Doug has [00:37:00] spouses using. Um, less taxing weight and amplifying its effect by angles and leverages, which is brilliant. But if you, but if your goal is to be able to dead lift 600 pounds, you're not going to be able to train each individual muscle independently and then just get up there and deadlift, you're going to have to dead lift 600

[00:37:21] Coach Rob Regish: [00:37:21] pounds.

[00:37:23] Yeah. Um, so much like what I discussed last week, you know, the, the real key to super strength. Is learning the contract as many, as much muscle as possible. Simultaneously

[00:37:34] Carl Lanore: [00:37:34] I call it amperage. I call it. So, you know, there's voltage and there's amperage, right? You can have 120 volts and a couple milli amps, and you can't even light up a light bulb, but you take 120 volts and you put five or six amps into it and you can electrocute a human being into death.

[00:37:50] Right.

[00:37:51] Coach Rob Regish: [00:37:51] So

[00:37:52] Carl Lanore: [00:37:52] activating a muscle is like, is like voltage. Activating, lots of muscles takes amperage, and that is [00:38:00] collateral adaptations to the nervous system that make it, allow it to focus on 12 different muscle groups and stimulate them at the same time. That's amperage.

[00:38:10] Coach Rob Regish: [00:38:10] Yeah. And that's, that's just been my, my goal and my stick throughout life.

[00:38:16] It's not everyone's. Um, and I'll listen to his stuff and I'll tell you why, you know, there may be a place for it where. Somebody like me spends his entire life doing big compound lifts and trying to get stronger and stronger. Uh, but, uh, look, there are no 80 year old squatting and deadlifting 500 pounds in gyms right there.

[00:38:36] There's a reason for that. And so, you know, is it plausible? I switch over to this at some point. Yeah. I agree with you, you know? Right.

[00:38:45] Carl Lanore: [00:38:45] Depends on your goals. Change. Like I said, it depends on what you're trying to achieve your goals change.

[00:38:50] Coach Rob Regish: [00:38:50] Right?

[00:38:51] Carl Lanore: [00:38:51] So I'm rusty. Brooke says, what's your take on mega dosing, beta alanine itchy.

[00:38:57] Uh, I saw an article saying that [00:39:00] six grams a day might not be enough and I want to get the most out of it. I can.

[00:39:05] Coach Rob Regish: [00:39:05] Yeah. Interesting thing here. Um, a couple of things that I noticed recently, most major companies with a beta alanine only product have dropped it. And, and I have to believe that's because people don't think right that it's working or, or warranty expense, even though it's not terribly expensive where it does show up a lot is in people's pre-workouts and in no small, no small measure, uh, because the company realizes that you get the tingles.

[00:39:38] Well, it must be doing something right. So we still have these questions about beta alanine and this one is certainly valid. You know, what about megadosing? In my opinion, on mega dosing, is this, it would be a very bad thing to do. Now, let me tell you why, because once again, I learned the hard way on this one.

[00:40:00] [00:40:00] Okay. I dosed 10 grams a day or more around about a year ago. And I quickly regretted it. Why? Uh, because I started having heart palpitations or maybe more accurately, my heart was skipping beats. Uh, and so I do a little more research and it turns out that very high doses of beta alanine displaced Turing.

[00:40:25] Which among many of the things that taurine does, uh, Turing's also responsible for regulating heart rate. Now, interestingly enough, you can do the same thing to yourself, uh, by taking too much vitamin D. Now, in all fairness, it takes probably 20,000 IUs a day or more for long periods of time. Um, but when you take too much of it, it affects calcium.

[00:40:53] Dynamics in your body, which also of course are responsible for regulating heart rhythm. [00:41:00] Your heart skipping beats is a scary thing. Very scary. At least it was for me. And it doesn't, here's the thing, but those two, those two products too, it doesn't stop the day that you discontinue beta alanine or vitamin D.

[00:41:15] It takes days and in some cases weeks. So just understand that don't. Don't like, uh, start taking it again, thinking, well, gee, that didn't work. It must be something else with beta alanine. In particular, you need to understand the dynamics of how it's incorporated into muscle tissue. Um, And, and how long and how much and yada yada, now, as an example, as a, as a benchmark creatine increases, phosphocreatine levels dramatically in, in a relatively short period of time, a month or less sometimes just a week or two, depending whether or not you decide to, to front-load beta alanine, [00:42:00] however, is a different animal study show that muscle carnosine levels are still.

[00:42:05] Rising at the 12, 16 and even 20 week Mark or more now? Yes, it is a bit faster when consumed with food and that's because food causes an insulin response. So it's smart. If you're going to take it, let's take it with meals, but you won't be loaded. In just a few weeks, like, like you worked with creative team, it works the other way too, by the way, meaning muscle carnosine levels after you discontinue very slowly received months and months and months for those carnosine levels to come down to baseline where you were before you started supplementing with beta alanine.

[00:42:49] If you don't want to wait to get the, the buffering effect, you can experiment with phosphate loading. Right. And we know from, there's been a [00:43:00] lot of studies on that, uh, showing much favorable research on it. Although the caution is always there to go slow. Why? Because provided, you know, you can get and keep it down.

[00:43:15] Um, it provides a more acute effect. Yes. Buffering hydrogen ions. However, the gastrointestinal issues that you face are going to be, let's say urgent, most athletes will only try it once. And I have a sneaking suspicion, um, that any performance enhancement they see, it might not be due to the phosphate loading.

[00:43:44] I think it might be honestly due to the salt, right? Uh, so experimenting with maybe sea salt or a similar version of it around workouts might be helpful to you. A lot of us, because we're in we're lifting and [00:44:00] watching our diets. We're on low sodium diets. I'm not a fan. I am not, I think, low sodium diets cause more problems than adequate and maybe even high sodium diets.

[00:44:14] Sodium is a very powerful mineral, right? Just, just a little bit. And it can increase your, uh, bodily stores of water pretty dramatically. And in some cases that's exactly what the doctor ordered for people. And they'll see an increase in strength. So, you know, that's, that's beta alanine in a nutshell, don't mega dose.

[00:44:40] It, you know, I would take three, maybe five grams a day, every day with food and just let it do its thing. You know, you'll be fully loaded in four months, you know, three, four months, something like that.

[00:44:57] Carl Lanore: [00:44:57] The next question comes from. Greg [00:45:00] casting way. He says, I know you're a fan of amino acids and fast proteins, especially during workouts.

[00:45:06] Like a lot of people I use way and lots of it. Should I take a scoop before and after my workout? What do you do personally?

[00:45:15] Coach Rob Regish: [00:45:15] Well, for some clarification about, about my position on proteins provided they have a high biological value. Like we discussed earlier. Fast, medium or slow. They all have their benefits and drawbacks.

[00:45:30] Um, so we needed to define though, particularly for this question, what fast means, at least in the context that he's asking milk protein. As most people know as a combination of way in casing and casing lasts for up to seven hours in your system, right. Slowly just kind of trickle feeding, amino acids. Um, and like casing way is a quote unquote, intact protein, meaning it's this [00:46:00] string like a ladder, so to speak of amino acids that still needs to be deconstructed so faster.

[00:46:07] Not. It's broken down into its constituent amino acids. Yes. Faster than casing. Um, but it washes out, excuse me, washes out much faster too. At around the 90 minute Mark, most of ways aminos are gone and it takes sometimes up to 60 minutes to liberate those amino acids for them to show up in the bloodstream.

[00:46:29] So for intro workout, use where I think supplements are most helpful. For intro workout use, you need something faster. And that means either a hydrolyzed protein or freeform essential amino acids. Now, the studies will tell you hydrocephalic hydraulic hydrolyzed proteins are better and faster. I say that after comparing the two and using them and experimenting.

[00:47:00] [00:47:00] Forever with them. Essential aminos are better. Hydraulic. I draw selects I'd relatives,

[00:47:06] Carl Lanore: [00:47:06] hydraulic sets. Yeah, I know. I get the same problem.

[00:47:09] Coach Rob Regish: [00:47:09] Hydraulics that use Diane try peptides may still be faster, but frankly, we're talking a negligible difference. They're both extremely fast. Within minutes. The amino acids will show up in the bloodstream from my viewpoint.

[00:47:27] And everything, all the experimentation that I've done, essential aminos recover you better, which is a consequence in my opinion, of being far easier to manipulate the ratios of each amino acid. And even if you get a stock essential amino acids formula, which conforms to the national institutes of health recommendations, you will recover faster than using a hydrolyzed protein.

[00:47:54] Back to the ratios, the ratios, as I said, can be manipulated [00:48:00] and the ratios matter. And if you don't believe that or read these conclusions to have just one study that the researchers did on EAs the composition of the mixture of essential aminos, we have tested in this in previous, these was originally based on the composition of muscle protein.

[00:48:20] However changes in concentrations of blood amino acids after ingestion maybe caused by different clearance rates of individual amino acids. Here's the important part. Therefore adjustments in the composition of the drink could further improve the net muscle protein balance response. And in fact, if you follow the L the ladder studies after this one, which was published, I think in 2010, They did in fact achieve better numbers with a different amino acid sequence.

[00:48:56] Now with protein hydroceles [00:49:00] it is technically possible to create different amino peptide combinations via hydrolysis. They, I think the, in the old days they would use an acid wash today. They use some sort of enzyme bath, however, It that's beyond the ability of the average person, right. One would need the necessary lab equipment and frankly, a chemistry degree to figure out how to do that.

[00:49:27] Um, and even then, The process results in a lot of, um, proline residues, which are what gives hydrolyzed proteins, very, very bitter taste. Uh, you know, even the best supplements won't work if they taste so dreadful, you seldom use it, even if you do use it consistently. And I have. I've used high hydraulics it's sourced from casing from way from salmon and believe it or not from silk [00:50:00] cocoon protein, which was hydrolyzed down to an average molecular way to be between 90 and 150 daltons by way of comparison, the previous benchmark for low molecular weight was 250 daltons.

[00:50:15] So if anything was going to work. It was going to be this stuff right? 90 and a hundred between 90 and 150. Let me save you some money along with your taste buds. None of the hydraulics that's that that I've used do what essential amino acids do. And by that, I mean a proper blend of them. So here's the bottom line.

[00:50:39] Few people can afford, especially nowadays few people can afford. You know, a half a dozen different speed proteins or the lab equipment to create custom dye and tri peptide blends. So if you want to maximize your results, do the, do these two things. Number one, sip on [00:51:00] essential aminos, just prior to an in-between your sets in.

[00:51:05] Immediately after training have a scoop of thrive, which is by far the best casing way mix plus extras, plus extra essential amino acids, plus right. Extra glycine, et cetera, et cetera. You mix that in a little bit of heavy cream. Post-workout that is the absolute best that you can do based upon the information that we have and the products that we have today.

[00:51:32] And I guarantee if you do use it. You will see and feel the difference almost immediately.

[00:51:40] Carl Lanore: [00:51:40] I take a quick commercial break. When we come back, we have the blueprint tip of the day. You don't want to miss that. Stay tuned. We shall return.

[00:51:56] later in the show, we're going to talk about one of my favorite things to talk about, and that [00:52:00] is glyphosate. There appears to be some transgenerational epigenetic effects. This study comes out of a university that I'm very, very fond of the great land grant. University of Washington state, where a lot of this good information comes out from.

[00:52:16] So you're going to want to stay tuned for that. He goes, you know, we've been told for a better part of the past eight or nine years, at least that the glyphosate is completely safe. You can drink it by the glass. It's fine. So we'll, we're going to, we're going to talk about that in a little bit, but before we do that, we have, uh, Rob registers blueprint tip of the day, what the blueprint tip of the day Rob

[00:52:37] Coach Rob Regish: [00:52:37] tip of the day has to do with the merits of, uh, planning.

[00:52:41] And resilience. And you know, this might not be the most happy-go-lucky conversation to have, but we need to have it because I was contacted not that long ago by a guy. I know I've known him for awhile. Great guy. I mean, [00:53:00] just, you know, hardworking guy, uh, doing everything that he can to provide for his family.

[00:53:09] And he got hit. Bad and I'll go into it here quickly. Um, but yeah, today's tip has to do with planning and more, more accurately, Carl, as you once said, being resilient. Now, I'm not sure if my plans are just that bad or what, but I've had to fall back on plan B more than once in my life. And so that means either plan a didn't work or more likely it wasn't adequate versus.

[00:53:40] The circumstances that I was faced with. Uh, and if you don't think this applies to you think again, because whether it's a plateau, you hit in the gym, a divorce that comes at you from out of nowhere weather or job loss, or, or COVID closes your gym. And now you've got nowhere to [00:54:00] train. You need to have a plan and, and to be resilient, some problems are so severe.

[00:54:07] Or, or so many hit at once just surviving is winning. Just getting up the next day is winning. For some reason, I seem to, to know from an early age that at some point in my life, some terrible things were going to happen. And so early on I built walls, right. That would protect me first. I built physical walls.

[00:54:35] Meaning, I built myself up to be as big and strong as possible. And, you know, hoping that that would deter any potential problems later on. I learned how to fight and, and, uh, that obviously it goes hand in hand with it. Um, but I also, in retrospect, I built financial walls. Reasoning that if I have this [00:55:00] big pile of money, uh, that would see me through a job loss, which is something that I really, really feared.

[00:55:07] Right. I mean, who doesn't little did I know, you know, job loss, divorce, rhabdo, and unfortunately it's, you know, uh, Suicide in the family more than one. Um, and even worse would hit all at once. Pretty much. I for sure. Didn't think that those things would last for years and even get worse as time went on in retrospect, in retrospect.

[00:55:36] Um, I'm glad that I built those walls because if I hadn't. I don't know if I'd be here today. If I was still here, I wouldn't be in nearly as good shape. Let's put it that way. I don't wish any of that on anyone. Even my worst enemy. What I do wish is that you take the time to plan today to [00:56:00] build today. And build some of your own resilience that could be greater physical strength, right?

[00:56:07] Yeah. I have a feeling, everybody listening is already doing that, but there's also mental and emotional strength to make it through the difficult times. Um, it might mean you start saving a little money and you have a. Start an emergency fund and you need to do those things because I'm here to tell you that with few exceptions, nobody's going to help you.

[00:56:32] When hard times hit, this is something that took more out of me than even some of the events that I was confronted with, you know, prepare yourself now for good friends, maybe even your spouse, your employer, and family members to turn their back on you. When you need them the most. And I'll tell you now I am still very angry about that.

[00:56:59] It is [00:57:00] sad to know that there are people out there like this, but truth be told the world is full of them. Now, on the other side of the coin, you're going to meet some great people that stand by you and do everything they can to help you. Some of which, who don't even know you really well. You know, and Carla Knorr was one of those.

[00:57:26] So understand it. Won't all be bad. And hopefully you run into a car Eleanor of yourself, yourself when, when the tough time set. Uh, so look, I hear and see it all the time and it's just going to get worse with COVID. Why? Because a lot of people are losing their jobs. That's going to put a lot of pressure on their relationships and marriages and sadly their families, you know, and like I said earlier, I had somebody write me recently.

[00:57:59] I can't [00:58:00] even begin to tell you what a good guy this is. And he was completely blindsided. He came home one day and there was a note, there was a piece of paper on the kitchen table from his wife saying, so sorry, I took the kids and I'm going to split. All right. It left him with nothing. Actually. It was probably it's less than nothing.

[00:58:25] Um, because now he's going to have to pay for a pay for an attorney. And, you know, if family court, is there anything like it used to be, they'll probably mandate that he pays some obscene amount of child support, even when he doesn't have his job, because he lost his job too. So, you know, it won't be long maybe before they're threatening him with jail time.

[00:58:53] You know, if he doesn't pay something alimony. Um, so you see how this works, [00:59:00] you know, at one minute your life is going along as planned, but then disaster strikes don't think it can't happen to you because. One of the first things this guy told me was, you know what? I listened to you on SHR, talk about saving money or getting ready or having a plan.

[00:59:20] Um, he said, I had no warning. She was going to do this. And, and he said, I never saved a dime. I lost my job. And now he's using credit cards to pay for his attorney goes. That's going to have a long tail on it. Folks. It's, it's really going to hurt in on many different fronts before he's whole. Yeah, but he will be whole again.

[00:59:49] And hopefully with the help of some good people, like I said before, there's an old saying that goes like this. You hope for the best, but you plan for the worst. And that was true a [01:00:00] hundred years ago. It's true today. And it's going to be true a hundred years from now. So start building resilience today, whether that means saving 10 bucks a week, stocking up on essentials, maybe for COVID 20 God forbid, if that happens well or.

[01:00:20] Continuing to build your biceps. You can never invest enough in plan B and being resilient because you never know when you might need it.

[01:00:37] Yeah. I mean like you and I, Carl, right. We went through something very similar and, um, and it's sad, but. You know, the stats are what they are. What is it? 70% of marriages end in divorce,

[01:00:49] Carl Lanore: [01:00:49] 75. Now

[01:00:52] Coach Rob Regish: [01:00:52] I remember when it was like 50 or 60 and I'll be [01:01:00] honest. I never thought I'd get divorced, but boom, there I was.

[01:01:03] Carl Lanore: [01:01:03] Well, and like you said with what's going on right now with COVID and job losses and just the general stress of the election and all the drama that's really created by people outside of our. Little circles of life that bleed into our circles of life. People are more stressed now than ever before.

[01:01:20] Suicides are through the roof. I mean, you know, it's really, it's really a sad, sad statement because I don't believe government really cares. Uh, they act like they care. They're almost like an extension of Hollywood in that age. They act a certain way, but the policies they put in place don't really.

[01:01:41] Aren't really designed to truly help people. And it's a, it's a sad situation right now. There's a lot of people under a lot of stress, you know, I'm fortunate, but I'm not lucky. I have put 15 years into this show I showed up when nobody else [01:02:00] would. We're going to have a 15 anniversary show this Friday, you know, I mean, you just, you just, you just gotta keep working and building your game and don't worry about what's going on around you.

[01:02:13] That's really, really the answer to everything. That's true business, a true of life. It true of relationships. You got to, you got a good partner in the world. Focus all your energy on her. Have her focus, all her energy on you. You, you don't need everybody else out there.

[01:02:27] Coach Rob Regish: [01:02:27] It's true. Yeah, and just know that forever, however bad it is when you come out the other end, you know, look at me.

[01:02:38] I met the most wonderful woman in the world and she makes my life. Wonderful. I would have never met her. Right. If all that crap didn't happen. Yeah.

[01:02:50] Carl Lanore: [01:02:50] And that's the way to look at it. And even though that is the way to look at it, because that's an optimistic view, not a pessimistic, pessimistic view, pessimistic view will never take you far in life.

[01:03:00] [01:03:00] Uh, just one more time, let's go ahead and plug the current offer. So if you want to take advantage of the blueprint bulletin. You can get three months for 1499. Go to SHR network.biz/coach Rob use code SHR five and see what you're missing. Don't forget to check out this special bonus fat loss guide, especially for these holidays.

[01:03:22] You're going to need it, Rob. Thanks for being here today, brother. Thank you. All right, we're going to take one quick commercial break. And when we come back, we're going to talk about something very, very near and dear to my heart and very serious. And you should be. Listening with complete attention,

[01:03:38] Coach Rob Regish: [01:03:38] stay tuned.

[01:03:41] Carl Lanore: [01:03:41] We're ripped and we're ready.

[01:03:47] welcome. Back to superhuman radio. We're joined by Dr. Michael Skinner from the university of Washington, Washington state university.

[01:03:57] Coach Rob Regish: [01:03:57] I'm sorry,

[01:03:58] Carl Lanore: [01:03:58] a [01:04:00] fantastic university that I applaud because they produce some of the best. Research as it relates to chemical pesticides and herbicides. And today we're going to talk specifically about, uh, glyphosate or Roundup.

[01:04:14] Many of you have heard in the media, the past four or five years about glyphosate on both sides. You know, you have the scientists say, Oh, it's completely safe. You can drink it by the glass. Then you have other people who say all sorts of horrible things about it. And obviously, um, The truth usually lies somewhere in the middle, but this research is even more fascinating to me.

[01:04:34] Welcome to the show Dr. Skinner. Thanks very much. So, um, why, why, why this study, first of all, th th this particular study, uh, you looked at, uh, the transgenerational effects of glyphosate. Why? I mean, was this just the natural next progression and looking at this chemical compound or whether there's some.

[01:04:55] Things that you saw in the literature that said, wait, we need to see how far this goes [01:05:00] down the line.

[01:05:01] Coach Rob Regish: [01:05:01] Yeah.

[01:05:01] Dr. Michael Skinner, Ph.D.: [01:05:01] So about 20 years ago, we, uh, discovered this concept where an environmental exposure or toxicant could actually influence an individual and Shane's their sperm or egg. And that gets passed to the next generation.

[01:05:18] And subsequent generations. And so this is called it's through a process called epigenetics, which is not a genetic change in the DNA sequence, but it's small chemical modifications around the DNA that actually can change how the DNA functions that's epigenetics. So this, what we just described is an epigenetic transgenerational inheritance.

[01:05:38] So this truly is an non genetic form of inheritance. It's how biology. Input is influenced by the environment. So the environment can change things without changing the DNA sequence to change phenotypes, promote disease, or promote wellness, depending on what the environmental sort of things are. So this has been going on for [01:06:00] 20 years.

[01:06:00] We've looked at 16 or so different environmental toxicants, everything from DDT, fungicide, so forth. And the recent one we looked at because a couple of years ago we looked awake. I looked at Gaia glyphosate initially, because it's currently. In our current generation and actually for the past generation is one of the major environmental exposures we get.

[01:06:22] Okay. And so we wanted to find out if glyphosate would actually promote things generationally. So that's what we did in 2019. And we showed the glyphosate actually promotes transgenerational disease events. So what it is is the individual exposed. Isn't so much effected by the glyphosate. So in essence, what they've been saying that glyphosate is relatively safe is not completely incorrect in terms of most chemicals out there, it is relatively safe for directly,

[01:06:59] Carl Lanore: [01:06:59] right?

[01:06:59] It's not [01:07:00] acutely toxic.

[01:07:01] Coach Rob Regish: [01:07:01] Correct.

[01:07:01] Dr. Michael Skinner, Ph.D.: [01:07:01] So it doesn't impact. If you're exposed, it's not going to affect you as that much, but it can change your sperm or egg sets that you're going to pass that to your children and grandchildren and great grandchildren. And so if you look at disease in the subsequent generations where we did and a rodent model, we see dramatic increases in disease in the grandchildren, and great-grandchildren where there's no exposures.

[01:07:27] Essentially, you're passing this epigenetic change in your germline, sperm or egg to subsequent generations. So we call this generational toxicology. In other words, it's not so much the direct exposure where everybody looks today, it affects the future generations. And so essentially what it means is it's very, it's relatively safe for today's exposures.

[01:07:53] Individual direct exposure, but we really didn't know previously that could we, it could be affecting our great grandchildren [01:08:00] and dramatically increasing their disease, onset everything from obesity to heart disease, to prostate disease, reproductive defects, the whole gambit, these were affected in these transgenerational animals.

[01:08:12] So in the current study, what we showed is we actually can analyze the individuals. And identify which diseases they may be susceptible to get. So, because this is now been exposed since 1990, we have this programming in our genome and we're going to potentially pass it to our grandchildren. What can we do about it?

[01:08:35] We may not be able to fix it because it's already happened.

[01:08:39] Carl Lanore: [01:08:39] Right? So what you do

[01:08:40] Coach Rob Regish: [01:08:40] about it.

[01:08:41] Dr. Michael Skinner, Ph.D.: [01:08:41] So this, this, what we, this study shows is we can actually look. At the epigenetics of your DNA and your sperm or egg or other cell types to give a diagnostic to say what disease later in life, you may be more susceptible to get then by knowing that's the [01:09:00] case, preventative lifestyle changes and or therapeutics can be put in place to delay or prevent the onset of that disease.

[01:09:08] So this gives, uh, this, this first hint at, for this, these types of problems that have been programmed from all these generations of exposures into our genome. We might be able to use this newer technology for epigenetic diagnostics or biomarkers to actually try to develop a better preventative medicine in the future.

[01:09:28] Carl Lanore: [01:09:28] Okay. A couple of questions that are just bouncing around in my brain. The first one is, uh, the time of exposure. As it relates to the production of offspring. So is it if you've ever been exposed to glyphosate or is it if you are, the exposure is occurring when you are fathering that child?

[01:09:49] Dr. Michael Skinner, Ph.D.: [01:09:49] So we study the most sensitive time for exposures for any organism is during fetal development, embryonic development.

[01:09:59] So when the [01:10:00] fetus is developing in the gestating mother, Most organ systems are starting to develop and that's when they're most sensitive to environmental insults. So we actually do the exposure on a gestating female. And this gets passed for generations to come. Okay. Gotcha. However, lots of different labs, including our own have looked at adults, preconception adults.

[01:10:23] In other words, adults, that when exposed, they can change their germline epigenetics as in the throat. And then that can actually get passed as well. Things like that. Caloric restriction or high-fat diets, things like this will actually promote those generational effects, right? Subsequent generations from adult exposures as well.

[01:10:43] So the most sensitive period is during fetal development. The next one is early postnatal right after birth. The next one is during teenage years pubertal development. And once you become an adult. You're generally less resistant to your personal effects from these exposures, but it can still [01:11:00] affect your

[01:11:00] Coach Rob Regish: [01:11:00] germline.

[01:11:01] Carl Lanore: [01:11:01] So it's not like, Oh, I was exposed and these three different periods of time, but then I cleaned up, uh, and removed it all from my body. And now three years later after it's been removed, I'm going to have a baby. It's still, it's still a dominant effect. Epigenetic, correct?

[01:11:18] Dr. Michael Skinner, Ph.D.: [01:11:18] Right. The programming and the germline.

[01:11:21] Can become permanent throughout your, the rest of your life. And so essentially the way that works is males have a, what are called traumatogenic cells, that cells that make sperm and these four mitogenic cells have a STEM cell. If you change that STEM cell sprouted zone, then those are the cells that replenish all the sperm that are made constantly throughout your life.

[01:11:45] If you change that cell it's

[01:11:47] Carl Lanore: [01:11:47] permanent, you just changed the blueprint in the factory, basically, correct? Correct. So, um, you know, w we've talked about epigenetics on the show for a very long time. In fact, we've even had a couple, uh, uh, [01:12:00] epigenetic testing groups, one out of coal chronemics out of the UK. Uh, they are testing over 2 million.

[01:12:07] Data points on the DNA, um, epigenetic, uh, epigenetically on the DNA. And, and so we always talk about epigenetics from, um, an unwanted passive effect. Like I interviewed one of your colleagues many years ago about DDT and sperm line. You know, Jay changing. Um, we've talked about epigenetics on this show from a variety of different reasons, but it's always epigenetic bad, you know?

[01:12:41] Oh, the epigenetic change have bad outcomes. Surely we can figure out how to harness epigenetics and maybe do things to unwind the bad things. Shouldn't we be able to do that. Absolutely.

[01:12:53] Dr. Michael Skinner, Ph.D.: [01:12:53] So you have to understand previously for the past a hundred years, We [01:13:00] thought the DNA sequence, just the DNA sequence was the secret to life.

[01:13:05] That basically everything was determined from the sequence itself. Okay. It turns out that the sequence itself can't really do much, even though there's genes and things in this sequence. The way that those are regulated is through epigenetic marks on the DNA we'll turn genes on or off to give you different cell types and so forth.

[01:13:27] So normal biology uses epigenetics for normal development, your maturation, your phenotypes, that you have, everything is really controlled through this environmental epigenetics and how it's affecting the genetics. They all work together. And so essentially normal biology. Everything you can think of.

[01:13:44] That's good is in just as much due to genetic epigenetics as it is genetic. Now, if we have some environmental toxicant high-fat diets, caloric restriction, these are sort of abnormal environmental sort of things. Then you shift the [01:14:00] epigenetics. And most of those shifts will then promote some abnormality in the normal developmental process.

[01:14:07] So all you've done is sort of, it's more the environment that we need to pay attention to. If we have a bad environment, it's going to promote these physiological effects like disease onset. It's not due to the epigenetics intentionally doing it. It's just part of the conduit on how this works. Okay.

[01:14:25] Carl Lanore: [01:14:25] So it's interesting because I did a show with Joel green, brilliant guy, uh, earlier in the year where, you know, there's, there's this, um, all of these new diets, the keto diet, you know, the, uh, uh, obviously fasting has become a very big thing.

[01:14:42] Um, restricted calorie diet. And after reading some of the research, I. Assumed I thought, you know, let's say there's a husband and wife they're really into intimate and fasting and keto. They're checking their blood ketone levels every day and they're getting deeper and [01:15:00] deeper into keto. And they're just thrilled about it because within their community, they're just superstars and they happen to get pregnant.

[01:15:08] Correct. That baby is going to be imprinted with the genetics of a baby. That's coming into a world that. Is not abundant. This baby probably will have higher degree of thrifty genes because the baby is coming into a world with a mother and father is starving all the time. So, so you just validated that that is true.

[01:15:30] That is a truism because that, because if you're, if you're starving yourself, So that you can be the King person in your diet community. And I always say, if your diet comes with an annual cruise and a membership card, you're doing it for the wrong reason, but you know, it's, it's, it's like you, you are doing some really, really big things to the offspring that you're going to have some Dianne.

[01:15:52] So even diets have epigenetic effects.

[01:15:55] Dr. Michael Skinner, Ph.D.: [01:15:55] Correct? Correct. So for example, your years ago, about five, six [01:16:00] years ago, what we showed was if we did the same type of experiment I just showed you or just discussed with DDT. So we actually promote, hit it with DDT three generations later, the great grand offspring, 50% of the population, both males and females developed obesity.

[01:16:18] Such that essentially, depending on what the environmental factor is, it can promote relatively specific phenotypes for DDT estrogenic type substances. It promotes obesity. So if you have a caloric restriction situation, what you're doing is you're promoting the thrifty phenotype. What you just mentioned.

[01:16:38] What it is. Is your offspring have the capacity to now live on less calories?

[01:16:42] Carl Lanore: [01:16:42] Yeah, because there is because they're assuming that's the world. Yeah.

[01:16:46] Dr. Michael Skinner, Ph.D.: [01:16:46] If you give them an low calories, they have a susceptibility to develop obesity and that gets passed to their great grandchildren and great, great grandchildren as well.

[01:16:55] So, Yeah. If the pregnancy issue is really the critical one, if you're [01:17:00] going to have a child, you have to think about what's your germ cells seen. So if you actually sh reprogramming for most of your life, because of these chloric restricted diets, if your child is not on a caloric, ritualistic diet, they will have a susceptibility to obesity.

[01:17:15] These, this is the, we have to be more conscientious about our environment. It's not just a built-in program thing. Like we used to think about it for the past hundred years, like genetics, the environment can actually dramatically influences epigenetics and it can reprogram that genetics very quickly.

[01:17:34] This is how evolutionary biology works. This is how this new phenomena of non-genetic inheritance impacts every area or biology, not only where disease comes from, but how evolution works. And we didn't really know about this until very recently. So it's not that the genetics isn't really important. It really is.

[01:17:54] We can't live without it, but it's really the epigenetics working with the genetics is how [01:18:00] biology works. So this is a normal process. And if we shift now the environment to a bad environment, either caloric restriction or whatever, You're going to shift the epigenetics and it's really going to reprogram things then because it's reprogrammed.

[01:18:13] And if it gets into your sperm or egg, it's there in plants, they've shown this phenomena is permanent. It goes a hundred generations. The heat exposure of a plant kind of has been shown to actually change the flowering phenotype. And that was passed through an epigenetic process for over a hundred generations.

[01:18:32] So this becomes relatively permanently programmed. So with this paper that you, that we were discussing shows is we, Nick can now use the epigenetic changes as

[01:18:43] Coach Rob Regish: [01:18:43] biomarkers

[01:18:44] Dr. Michael Skinner, Ph.D.: [01:18:44] to give us a better predictive capacity, to know what abnormalities might develop later in life. And we then can actually take a preventative approach medicine wise

[01:18:54] Coach Rob Regish: [01:18:54] to prevent

[01:18:55] Dr. Michael Skinner, Ph.D.: [01:18:55] them, which is much easier than

[01:18:57] Carl Lanore: [01:18:57] what was it.

[01:18:57] Th th there were, there were a couple of very, very [01:19:00] common disease outcomes to the, uh, glyphosate exposed. Epigenetically changed offspring, prostate cancer.

[01:19:08] Dr. Michael Skinner, Ph.D.: [01:19:08] There was prostate disease, kidney disease, and, and test this disease infertility in the mail. Those were the most, there were three most prominent basically, but the highest population actually had multiple diseases.

[01:19:22] It's not just one. It's actually a good,

[01:19:24] Carl Lanore: [01:19:24] multiple. That's tough. Then when you have multiple diseases like that, it's very tough. I mean, the body isn't functioning right at all. Who knows what the downstream. Diseases that occur from those are right. If your kidneys aren't functioning, your liver's probably not functioning either.

[01:19:38] Dr. Michael Skinner, Ph.D.: [01:19:38] So the take home is the glyphosate, the way they designed it, the way that it's classically tested for toxicology shows that it is relatively safe compared to many other exposures. But what we didn't realize is all these exposures, including glyphosate promote generational impact. And so now what's what we don't [01:20:00] do anywhere else in the world right now is test for generational impacts of compounds like glyphosate.

[01:20:06] So we need now to step back and start analysis of these generational impacts to know, even though it may not be harmful for us to get exposed. If it's harmful for our grandchildren, it's just as bad to think about it. So that that generational toxicology needs to be start to be addressed. And right now we don't do any testing anywhere in the world for that concept.

[01:20:30] Carl Lanore: [01:20:30] So I had a scientist, um, that was with a think tank. I can't remember his name, Anthony something and Anthony Sam's Samsel. I think his name was if I remember correctly, about four years ago on the show that his group had discovered that. Glyphosate is a synthetic glycine and the body doesn't really know how to break it down the way it does glycine.

[01:20:54] So it accumulates in tissue and it causes a phenomenon called amyloidosis. The one [01:21:00] of the first studies, his group published was the, uh, uh, unusual phenomenon of Amidala amyloidosis of the heart, which leads to heart failure. And they indicated that it was because the body thinks it's glycine.

[01:21:13] Incorporates it into tissue, but when it comes time for, uh, uh, you know, for tissue turnover, autophagy, organelles, doing their job, they look at it and they go, well, we don't know what to do with that. We'll just leave it there. And they just build new tissue over it. And so, but now you're saying that some of these trans-generational epigenetic effects may be because it mimics.

[01:21:35] Uh, some hormones like maybe estrone, it seems like all, everything seems like BP BPA, everything, everything mimics estrogen. It seems like it's good to talk about that.

[01:21:45] Dr. Michael Skinner, Ph.D.: [01:21:45] No, I mean, essentially, uh, not all, but probably I guess between 30 to 40% of all environmental chemicals have usually winter called an endocrine disruptor effect.

[01:21:58] It's an androgen [01:22:00] receptor and estrogen receptor. It's some hormone system. Gets abnormally influence either it's inhibited or super stimulated or something like that. And so these, the hormone system, these endocrine disruptors, and then that's what they do is they disrupt the endocrine system. They can actually, they are the ones that are probably more active in promoting these sort of disease, phenotypes, but glyphosate.

[01:22:21] It's really not a hormone like substance. It doesn't really interfere like an endocrine disruptor. We don't really in a mammo and a know how, what, what it is, what it's doing per se. All we know is that there are some with direct effects. There are a couple of little things coming on, but for these transgenerational things, clearly the germline is being affected by the glyphosate to change it's normal epigenetics.

[01:22:45] So the epigenetics, it's the chemical modifications that are supposed to occur either don't occur or there's too many such that the end result is you have a germline that has a shifted epigenetics. So the offspring and grant offspring and so forth now have the [01:23:00] ability or it'll promote them to have a disease susceptibility.

[01:23:03] It doesn't really promote the disease. It just, the susceptibility, you have to understand in disease, ecology, if someone has a susceptibility to get obesity, On the same caloric content that you might take. If they take that same caloric content, they will develop obesity and you won't. So disease often is a susceptibility issue and many things like diet and exercise and so forth will actually shove it one way or the other as to whether you get the disease onset.

[01:23:32] What this epigenetics is doing generationally is shifting that susceptibility index. So these individuals now have a higher susceptibility for it based on their diet and exercise and so forth. Okay.

[01:23:45] Carl Lanore: [01:23:45] So, um, the microbiome is a fascinating new area that more and more scientists are starting to incorporate into their own work to see what role it plays in, in the outcome of diseases and in the area of glyphosate, [01:24:00] that the reason it was considered safe is because humans don't have a shit gamete, uh, pathway.

[01:24:06] In our, in our, in our tissue, but we have microbes in our gut that respond to glyphosate. So I wonder if you could also look at the microbiome diversity of the parents and the offspring to see if there is, uh, a signature in those versus wild type mice that weren't exposed and haven't had epigenetic changes.

[01:24:32] Dr. Michael Skinner, Ph.D.: [01:24:32] No, no. What you would say is. Let's say we have a population with a certain type of microbiome, bacteria, and viral sort of components in your digestive system. If you expose them with glyphosate, would you shift that? Uh, because of the glyphosate exposure. So I don't think I'm not aware of a study that's directly done that, but because of that shift, there are physiological impacts of the microbiome that you could actually change.

[01:25:00] [01:25:00] What we're talking about is more, a direct effect of the glyphosate. On the actual germ cells or supporting cells for the germ cells to shift its normal biology.

[01:25:11] Carl Lanore: [01:25:11] Okay. Not, not translated, not translated through the microbiome. No,

[01:25:16] Dr. Michael Skinner, Ph.D.: [01:25:16] but you could potentially alter that microbiome through the direct exposure.

[01:25:20] If that happens. It would just be in that individual. If you change your diet, if you no longer expose, it might simply recover or something. Those are things that haven't really been looked at that I'm

[01:25:30] Coach Rob Regish: [01:25:30] aware of.

[01:25:31] Carl Lanore: [01:25:31] I I'm going to put this question up, but you are not a virologist. I assume you're not. And, and obviously vaccines are a lightning rod right now, but, uh, Robert Thompson is asking can the vac can of vaccine like the coronavirus vaccine effect epigenetics and I, I would imagine everything if diet can affect epigenetics, I'm sure vaccines can as well.

[01:25:51] Correct.

[01:25:52] Dr. Michael Skinner, Ph.D.: [01:25:52] The immune response you have during infection is a different physiological state that can affect a number of different things. [01:26:00] Um, although it hasn't been shown with a virus yet with some, some communicable diseases, mostly, uh, parasites and things those have been shown to cause an a, of a change in the individual to change the epigenetics of the germline and coat that promote that transgenerationally.

[01:26:18] So viral infections are likely to do the same thing, but the direct data for that has not been come out to show that you can actually change the germline epigenetics and for generational stuff. That's the critical thing. And only the sperm or egg pass, anything to the next generation, right. For the individual.

[01:26:35] However, it's a big deal. If, if you were young, this is why, uh, individual that's correct. The coronavirus is, let's say the age of one or two or five or something like that. And they get infected because many organ systems are still in development and ongoing epigenetic changes. The simple existence of that infection can shift those things, whether that's going to impact their heart later on or their [01:27:00] brain later on, or things like that.

[01:27:01] Those are studies that have, you know, our, I believe her in process, but haven't really been. Uh, published or anything, but I suspect that younger generation individuals will be more responsive to have these changes. So it's it. Later in life they'll have diseases associated as adults. We won't have that because everything's already developed too.

[01:27:21] When we get ex uh, infected that may influence that the transient infection period. But it won't necessarily permanently shift organ systems because we've already got them developed. It's a younger children and certainly fetus and so forth that are most sensitive to the

[01:27:38] Carl Lanore: [01:27:38] potential. We're talking about one chemical compound in the environment today.

[01:27:43] And as you know, and as your university has spent a lot of time identifying, there are literally hundreds of these chemical compounds. In our environment today, and many of them have trans-generational epigenetic effects. Sadly. Do you ever feel hopeless, but being in, [01:28:00] being in the center of all this information, do you ever think to yourself?

[01:28:02] Wow, we have really EFT ourselves.

[01:28:05] Dr. Michael Skinner, Ph.D.: [01:28:05] Well to a degree, that's why we're doing the studies we're doing now. In other words, showing like today and the public publication that was just published, that we can actually use epigenetic biomarkers to, to diagnose the susceptibility, to get disease. So it's the, we could use preventative treatments to prevent that disease developing the, or recently we've found that essentially, if we look at the epigenetics of the sperm, We can tell a father what potential the diseases they're offspring may be more susceptible to get as they get older.

[01:28:40] And so those types of diagnostics will give us the ability to determine that. And so that then down the line, we can use preventative sort of approaches to address problem. So that's why we're doing this sort of thing. In other words, years ago, we spent lots of times as showing that the phenomena existed.

[01:29:00] [01:29:00] There's little, little controversy now that the phenomena exists because it's been done by so many different people in so many different systems, but now it is fairly doom and gloom, you know, what's your great grandmother. Got exposed to when she was pregnant. Maybe gonna give you a disease later in life.

[01:29:18] What can we do about it? And you're going to pass it on to your grandkids. So what can we do about it? Well, these preventative therapeutics through this epigenetic biomarkers would give us a way to at least treat it. We may not be able to fix it, but at least can treat it in the future. So that's the way I would view it.

[01:29:34] Is this particular paper in general. So the first step to allow us to get to that future sort of three.

[01:29:41] Carl Lanore: [01:29:41] So really testing a man sperm, even if the already had children and he's in his thirties and forties could actually help him understand what diseases that lie in his future. And we're talking about his stones.

[01:29:55] When we talk about sperm, right? We talk about the, uh, the histone. No.

[01:29:59] Dr. Michael Skinner, Ph.D.: [01:29:59] Well, [01:30:00] we have histones, we'll do the same thing. Like this paper showed his histone effects in the sperm were a good biomarker, but the main biomarker that most people study in the we study as well. It's called DNA methylation. It's a methyl group.

[01:30:14] That's a chemical modification of the DNA that basically can turn genes on and off. But in sperm, we have these histone sort of sites that actually could also be used as a diagnostic. And this, this paper actually is one of the first papers to show that that phenomena could potentially exist.

[01:30:32] Carl Lanore: [01:30:32] This is fascinating stuff.

[01:30:33] And at the same time, it just depresses me. Well, I mean, I, I, you know, it's, you, you come into this world, you try to do the best you can. And we know there's things that outside of our control, but to think that there's something that your great-grandmother did is affecting. Like it isn't even her, it's not even a genetic anomaly.

[01:30:53] It's not like as though she had the gene for this disease. It's just because she became, she worked at a factory and was [01:31:00] exposed to this chemical and then she had children and they had children and you got it. So every decision your ancestors made somehow fall upon you one way or the other, correct.

[01:31:09] Dr. Michael Skinner, Ph.D.: [01:31:09] That's a different way to think about disease etiology. In other words, why is it 50% of our population in the U S has obesity that susceptibility probably has a lot to do with the 1950s exposure to DDT. And so these generational impacts really can be kind of explain what's going on today. So with this sort of step forward and getting coming up with epigenetic diagnostics,

[01:31:33] Coach Rob Regish: [01:31:33] BioMarin.

[01:31:35] Dr. Michael Skinner, Ph.D.: [01:31:35] We might be able to treat

[01:31:36] Carl Lanore: [01:31:36] the situation. Yeah. Cause we'll know about it ahead of time. You'll know that before the disease shows up, you say, Oh my God, you have a predisposition for this kidney disease. You know, you need to control these things in your environment. You need to do this. You need to take this away.

[01:31:50] We'll take a

[01:31:50] Dr. Michael Skinner, Ph.D.: [01:31:50] therapeutic that actually would directly address it. Correct. Right. The best example is right now, our best, one of our better examples of a preventative therapeutic is [01:32:00] Tamoxifen. Tamoxifen was a chemotherapy used to treat breast cancer. This isn't really good at treating breast cancer after it develops, but it turns out if you take Tamoxifen in your thirties for a couple of years, you can delay the onset of breast cancer by 10 or 15 years later in life.

[01:32:19] So essentially it's a true preventative therapeutic. The problem today is we don't know who to give it to. We don't know what the woman that's definitely going to get breast cancer. And so it's sort of a mixed bag with these epigenetic biomarkers. Boom. We potentially have a biomarker to say later in life, you have a such and such percentage chance you're going to get this disease.

[01:32:40] So if you take this therapeutic for a couple of years, potentially, you're going to delay its onset. That's a that's preventative medicine that we can't do today because we don't have

[01:32:49] Carl Lanore: [01:32:49] any biomarkers. Yeah. This is interesting. I want to thank you so much for coming on the show today, Dr.

[01:32:55] Coach Rob Regish: [01:32:55] Skinner. No

[01:32:56] Dr. Michael Skinner, Ph.D.: [01:32:56] problem.

[01:32:57] It was a pleasure and I appreciate the interest

[01:32:59] Carl Lanore: [01:32:59] take care. [01:33:00] Well, we'll have you back on again. We'll keep an eye out for your work and if you want to keep in touch with Elisa, when your group is publishing, maybe someone else that's in your that's in your clinic there. Just, just send her an email. We'll get you back on.

[01:33:11] Coach Rob Regish: [01:33:11] All right.

[01:33:11] Carl Lanore: [01:33:11] Thank you. Take, take, take care. And that's it for today's show. We have nothing else to talk about. That's fascinating and makes me so sad. It makes me sad because there are so many companies out there selling stuff that's going to harm us and we just don't even know it yet. And we buy it willingly and, you know, There's no such thing as protecting the public.

[01:33:33] I don't even want to get into it. You got to learn to protect yourself, make good decisions. Uh, okay. We have a great show for you tomorrow too. Friday is our anniversary show. 15 years in continuous production. No small feat. Uh, so please show up for that show live. If you want to be memorialized in that door, immortalized in that show.

[01:33:54] You could do one of two things. You can either email [01:34:00] This email address is being protected from spambots. You need JavaScript enabled to view it., and simply put the year you first started listening and your name. That's it. It's going to be, it's going to be on, on the screen throughout the whole show. All these names are going to scroll, or if you want to do a little something extra, uh, take a video with your iPhone.

[01:34:16] Wishing the show, uh, happy 15th anniversary, and then click. Uh, go to your browser and go to SHR network.biz/your story and upload the video there and we'll get it on, on the air as well. I see you tomorrow with more superhuman radio. Thank you for listening today. [01:35:00]



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Super Human Radio is the world's longest running broadcast dedicated to health, fitness & anti-aging with an emphasis on exercise, nutrition, and hormone management. This one of the most progressive podcasts for preventative & regenerative techniques designed to increase longevity. More

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SHR Logo

Super Human Radio is the world's longest running broadcast dedicated to fitness, health, and anti-aging with emphasis on exercise, nutrition, and hormone management. The most progressive source of information for preventative & regenerative techniques... More

2908 Brownsboro Rd Ste 103
Louisville, Kentucky 40206
United States of America

+1 502-690-2200