[00:00:00] Carl Lanore: [00:00:00] The end of the day, I'm just a big chimpanzee. Cause when I see my face, I smile. Welcome back to super human radio. Today is, uh, February 9th, 2021. And we have a great show planned for you today now. Uh, creatine may very well be the most studied, uh, ergogenic, uh, sports supplement in the world. And my guests will be able to correct me if I'm wrong.

[00:00:24] Um, it's ability to increase, uh, muscle's ability to work longer and harder, uh, has been well-documented. Um, it also imparts almost immediate gains in muscle size. We'll discuss that phenomenon and why that happens. It turns out that creatine does a lot of other amazing things for health and longevity that, you know, while not as sexy may actually be much more important, then your, uh, vain, uh, desire to be more muscular.

[00:00:54] But regardless of why you use creatine, the takeaway of today's show will definitely [00:01:00] be that you should be using creatine all the time. Uh, and. Before we get started. Of course I have to thank our title sponsor. And that is legendary foods. Legendary food, just introduced a brand new tasty, pastry it's flakier and puffier, uh, kind of like Apple turnover, uh, type, uh, pastry, then the original tasty pastry, which is more like a, a hard, uh, pop tart, and then new red velvet flavor.

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[00:02:17] All you have to do is listen during the commercial break. There's a secret word in my voice, hidden between commercial spots. When you hear it, write it down into an email, send it to on This email address is being protected from spambots. You need JavaScript enabled to view it. and you are entered to win your own box of tasty pastries. So don't wait second, listen hard during the commercial break and without further delay, I'll bring my guests on.

[00:02:42] He's a returning guest to the show and a guy that I sit down and talk with. We'll break for 10 seconds. And I'm like, man. I got to have this guy on the show. More often we share a common bond because we're both from Brooklyn. We both love physical culture, Glenn and, and, uh, and also we [00:03:00] both had interesting paths at the end of today's show.

[00:03:02] After we're done talking about Korea team, we're going to talk about something that's a little less than known about will brink. I'm not going to share what it is yet. So you're going to have to tune in and stay with us. So will you, uh, I am nominating you as the official patron Saint of Korea team.

[00:03:18] Because no one, no one has studied creating more written about creating more than you. I believe. So. I

[00:03:27] Will Brink: [00:03:27] will say, I think you're accurate. I I'm generally a pretty humble guy, but I have to give myself the credit there. Uh, yes, I, um, I really was the first person to publish articles in the magazines and stuff about the, the non, the non-exercise uses of creaking, the medical uses and the anti-aging uses the longevity uses, which, you know, every time I think.

[00:03:48] I've learned all there is no about creatine. It just comes up with some new study will come up and blow me away in an area. I didn't even think it could have a benefit. And this has been going on for about 30 years. I mean, when I was writing about [00:04:00] the benefits of creatine, uh, you know, there wasn't an internet, you know, I know a lot of, uh, younger people watching this.

[00:04:05] Don't actually remember there was a time minus internet, remember those number of those days, but there wasn't, there wasn't a time without internet. So, uh, yeah, I I've been writing about, uh, The benefits of creating specifically, like, let's say the non-athletic parts, the anti-aging benefits of the brain, you know, the brain parts, the mood parts.

[00:04:22] Uh, and like I say, I just today, I mean, I was reading three new studies that just blew my mind. I just, I keep thinking if there's everything, anything, you know, new to learn, um, you know, I, I know what by now, where there's nothing new under the sun, it just, uh, it, it goes on and on and on. And one of the, one of the frustrating things about creating for me, at least having been in this game a long time, Is this an old supplement, you'll talk to somebody, you know, average person, you know, and say, what do you know?

[00:04:48] How about, Oh, I know all about creatine. It, you know, it's good for the eye. I use it when I work out, you know, it's good stuff. And that immediately tells me they don't know shit about creatine, right. Because it's been around a long time. Everybody's just, Oh, [00:05:00] Creotine I know all about creating it. And the reality is they don't, uh, I'm actually always blown away by the number of people, even, you know, who use it or, or are you supplements or in the gym?

[00:05:11] Who knows. So little about the benefits of creating. I mean, of course we expect the average person on the street, not to know a thing about it. Uh, it's, uh, according to them, it's a steroid FATF you remember? Right. Right. Um, you know, or your average doctor doesn't really know much about creating, but I'm always amazed by the percentage of people who are in the, you know, in the gym or into health, into eating well, who, who still really don't know much about creating that, that parts are always kind of blows me away.

[00:05:36] So

[00:05:36] Carl Lanore: [00:05:36] let's start with the remedial stuff for just a second. We're just kind of going to do the reader's digest version of this. First of all, creatine is, is it considered a non-essential amino acid because it's built by other amino acids.

[00:05:48] Will Brink: [00:05:48] It's not even considered an amino acid in the classic sense. It's an, it it's usually listens like amino acid derivative, or an amino acid, like compound.

[00:05:56] It sort of floats in this odd spot, but it's not technically an amino [00:06:00] acid, uh, because it gets a combination of three amino.

[00:06:03] Carl Lanore: [00:06:03] Okay. So with that being said, wow, I guess it could be a short protein peptide, if you want to think of it that way.

[00:06:09] Will Brink: [00:06:09] No. Yeah. I don't know if it's even long enough. Yeah. I mean,

[00:06:12] Carl Lanore: [00:06:12] I don't think, and they have, they have some three peptide, uh, you know, some,

[00:06:15] Will Brink: [00:06:15] yeah, we do, but it's, it's not the, the way the, the, the model, the way those amino acids are modified.

[00:06:20] They're not just ma they're not just, uh, amino acids connected by a peptide bond. So they're not, they wouldn't be a tripeptide, it's a new molecule altogether. Okay. So

[00:06:31] Carl Lanore: [00:06:31] what I'm trying to say, the. Benefits from an ergogenic standpoint, is that create the available muscle creatine helps to recycle ATP so that you can train longer, get a couple extra reps, even be a little bit stronger.

[00:06:46] Am I correct with that? Yeah.

[00:06:48] Will Brink: [00:06:48] Yeah. That's that's, that's the basic under the hood premise. Um, there there's, there might be more to it. I mean, one of the interesting things, of course, I think you had mentioned earlier is there is interest cellular [00:07:00] water. So the, but it's interesting that. Uh, the, the cellular, the hydration state of the cell is an anabolic signal onto itself.

[00:07:09] And it makes, again, it makes terms of sense, right? You've got a dehydrating sail. It's not going to be turning on protein. Synthesis is trying to survive, right. If the, if they sell as well, hydrated is actually an anabolic signal to turn on. So this is why. You will put on like weight with creatine early on.

[00:07:24] Right? You might put on a cake, you know, three, four pounds early on and people like to say, Oh, it's just waterway. Well, it's intracellular water. Wait, what are these not water retention. Right. And it's an, and what happens is that, then it goes on to be its own anabolic signal to the cell. And so there's a short-term gain.

[00:07:41] Right? And then there is a, a longer term effect where you are turning on the machinery and the protein synthetic stuff. Of course, if you're, you got to give it a stimulus of course, and lift some weights and all that other good stuff, but right. So there's a, there's a sort of a multi-pronged effect that goes on, uh, with creative besides just that early

[00:07:56] Carl Lanore: [00:07:56] waterway.

[00:07:57] I want to get Carlo, uh, uh, Carlo [00:08:00] Capone's, uh, Comment up here again, he liked creating HCL. Is there any evidence that any of these other modified forms of creating are any better than creating amount of height?

[00:08:12] Will Brink: [00:08:12] Not a damn bit. So,

[00:08:15] Carl Lanore: [00:08:15] so whichever one you like taking it, that's taking just take it, that's it?

[00:08:18] Well,

[00:08:19] Will Brink: [00:08:19] no, I'm going to be a little harder on this. Um, you know, there's like a zillion of them out there ranging from. Probably know better, but no harm done. If you just, you prefer, do you want to spend the money to a bunch of garbage, complete nonsense? Uh, it is is less, less value to Korea team. Uh, you mentioned creatine monohydrate is the one with all the data period.

[00:08:40] Um, HDL for example, I think looks interesting. It again has very minimal data there. The one study that was done again showed it was not superior in any way. It is, of course it is considerably more expensive. So again, milligram per milligram, you know, which, what should you take creatine? Hydrochloride at least does not look like a scam.

[00:08:58] So if you like it, [00:09:00] you don't mind spending the money. Go ahead. But there's a long list of them that are straight up bullshit scams, um, that are, you really are wasting money in way that I have an article on the brink zone called the creating graveyard where I, where I, where I say that this bullshit creatine is going to die.

[00:09:15] So if anybody wants to go read up, I have a whole list of the ones that I say are maybe worth using. Probably not worth using and so forth, but, uh, no, I took to date for the most part. There's no reason to creatine monohydrate is dirt cheap. It's got all the safety data, it's got all the benefit data. Um, and there really isn't.

[00:09:31] I haven't seen any yet any reason to use anything else, you know, until somebody comes up, you know, there's no, here's the thing about creating, right? It it's, it's a commodity this point it's so cheap. There's really no profit margins on it in any real sense of, so. What companies need to do, understandably is look for, is look for something else that, you know, sounds wonderful and amazing and new and cutting it.

[00:09:53] And, uh, yeah, and so charge it, charge a bunch for it. Um, creating really doesn't have any, the only real drawback to the monohydrate. It's [00:10:00] just not very soluble. That is it's the Achilles heel of treating monohydrates is poor solubility. Uh, and so suddenly by hydrochloride is S has better solubility. Um, but again, from an absorption standpoint, what I tell people to do, um, Is again, it's something I started doing, telling people 30 well, 20 years ago, or so it was just a prejudice, all that in hot liquids, coffee,

[00:10:23] Carl Lanore: [00:10:23] coffee.

[00:10:23] Well, well, I want to, I got to correct somebody. So, um, so Robert Thompson is a big fan of yours and he said bomb-proof coffee. Yes. But the reality is that the name has changed and I'm going to put the website up here cause it be available for sale. Very surely alpha Joe coffee.com. Uh, take your coffee to an 11.

[00:10:44] Right here. Yeah, yeah, yeah. So there you go. That's the new product and that's where you'll be able to get it very shortly. He's waiting for a shipment of creatine of all things, uh, so that they can, uh, uh, fire up the press and produce them. Yep. And

[00:10:57] Will Brink: [00:10:57] the other of course, topic w we could get into a little bit, is [00:11:00] talking about, uh, sources of creatine.

[00:11:01] Monohydrate. I mean, there's, there's only two places left in the world where creatine monohydrate is made and that's China and Germany and. You know, back in the day, again, there was a bunch of manufacturers, there was fan steel and there was, uh, there was one at Italy and there was some American, but. Um, over time, basically the Chinese, they put everybody out of the business.

[00:11:19] Carl Lanore: [00:11:19] It's a commodity item who he can't make any money on creatine. Monohydrate, that's the beauty of it. Walter evidence said, you know, and plus it's cheap as dirt. He's absolutely right. Um, but it works, it works magically. Um, I've taken creatine for probably over 20 years. I took off, I take off every now and then, and then kick it back in.

[00:11:37] So, um, before we, before we start talking. How about some of the science you've blogged about and I'll get to everybody else's comments everybody wants to talk to will. So sit tight. Uh, I'll make sure all of you get a minute. Um, those of you who are listening to this show that are vegans or no vegans, this is a really, really, really important show for you because if you're vegan, you get [00:12:00] zero kreatin in your diet.

[00:12:01] None. The only, the only source of creating an animal sources and correct me if I'm wrong, tuna and pork. Top of the list for, for creating a per pound of muscle meat. Uh, beef is in there, turkeys in there, but tuna and pork have the highest levels of creatine in most of

[00:12:19] Will Brink: [00:12:19] them. Um, no exact tuna. Uh, of course I'm going to, Oh, gee, I'm not, I'm forgetting the fish.

[00:12:24] Maybe somebody watching this will remember. Uh, it's probably, it's a really terrible tasting fish that nobody would want to eat every day. And of course, I'm, of course I'm blanking on, but, uh, it's, uh, it's not tuna. It's a different fish. Uh, it's a really smelly fish, right? Yeah. But yeah, it's, as far as dietary is concerned.

[00:12:39] Yeah. It comes from animal. You can make it yourself. Of course. Otherwise, you know, if you, if you, if you rely on it completely from your diet, you, you die so you can produce it yourself. But as you said, vegans are notoriously low in tissue, creatine levels. Um, there's. There's this is, I don't know what the cause of causes, but a lot of people don't like to talk about this in the vegan world, but there's also a lot of studies showing that [00:13:00] vegans vegetarian or vegan, especially suffer from a lot more mood disorders, depression and so forth.

[00:13:06] Now, chicken or the egg. We don't know. However, there is also really good data showing that creatine again, creating levels. Are correlated with mood and depression. And I also have articles and studies about that on brimstone. And there are, uh, there are actual studies feeding people, a creatine, and, you know, they do find benefits in mood.

[00:13:26] So, uh, is that one of least, I mean, is that one reason that vegans and vegetarians have. Um, greater

[00:13:33] Carl Lanore: [00:13:33] level. I would say it's one. I would say it's one of them. Cause there's a lot of things. There's a lot of nutrient deficiencies, if you're a vegan and you're not supplementing, but

[00:13:42] Will Brink: [00:13:42] I'm wondering if that's one of them, at least.

[00:13:43] Yeah. This is medium fatty acids. B12 carnosine yeah, it goes on and on. And now

[00:13:50] the

[00:13:50] Carl Lanore: [00:13:50] vegans will argue with, you know, we get omega-3 fatty acids and linolenic at no, the only the triglyceride bound from fish are actually the ones that work just for the record.

[00:14:00] [00:13:59] Will Brink: [00:13:59] Right. Well, the other problem of course, is the conversion rates of linoleic acid and LNA in LA are very, very poor.

[00:14:07] They're like one to 2% women are a little better as you get older, it gets worse and yada, yada, yada. So yeah. You'd have to eat a lot of, of LNA and stuff to get a high amount of, um, of actual fish oils. Quote-unquote fish oils. I mean, we call it fish oils, but they're DHA and EPA basically. So they're, they're the, they're the, the hydrogenated, uh, version of, of LNA.

[00:14:27] Carl Lanore: [00:14:27] Let's start off with one of your articles that the title intrigued, everybody who looked at it, it was about a baby was saved by using creatine. Monohydrate talk

[00:14:37] Will Brink: [00:14:37] about. That's an absolute fact, man. I know it sounds like melodramatic.

[00:14:42] Carl Lanore: [00:14:42] It sounds like something you'd see on the mirror or the other Inquirer

[00:14:45] Will Brink: [00:14:45] or the kid fell out of the tree and they say, you know, that the, uh, the fireman caught him, but no legit.

[00:14:51] Um, so there's something called, um, uh, it, it, it's an internal, a genetic problem where, uh, for example, cerebral palsy is [00:15:00] mistaken, a cerebral palsy. So there's genetic, there's genetic deficiencies that kids are tested for. Unfortunately, this one is not, I don't know why, but it should be. And it's a genetic deficiency where the kid is missing is genetically missing an enzyme to produce karate.

[00:15:13] It's that simple and it's, and it's mistaken. It's misdiagnosed as cerebral palsy, which is a horrible, you know, here's something you can completely cure this kid. Uh, it's called an internal, uh, error of metabolism and, um, It's a simple test. It's one that should be added in with all the other tests that they have for, you know, for infants that come out just to make sure they don't have it.

[00:15:33] It's not that common, but I mean, imagine, you know, you've got some kid who get diagnosed with cerebral palsy who was going to have a miserable life and he, and he can be saved. I mean, he can be saved by a dirt cheap supplement. So, yeah, legit legitimately kids can be and are saved by a simple test, that test for this genetic deficiency where they can produce creatine.

[00:15:53] And if they have it, all they got to do is feed them, create a team, you know, effing, miraculous cure, you know, done. Right. And [00:16:00] that's about as perfect a scenario as you can ask for. Right. I

[00:16:02] talk

[00:16:02] Carl Lanore: [00:16:02] about this is basically a, a nutrient deficiency. So it just goes to show you how important creatine

[00:16:08] Will Brink: [00:16:08] actually is.

[00:16:09] Yeah, well, creatine, I mean, again for brain function for especially young brains, but for brain function, no, no creatine. You're going to die. I mean, you're, you know, basically it looks like cerebral palsy and the kid dies a miserable, slow death because his brain can not, can not produce creating. So the second part of that, of that, that article.

[00:16:25] Was it a paper when we started out saying we just had some papers just came out that, that I really amaze me. And one that just came out was actually found that creatine status is also correlated with, with, with fertility and women, the, the, um, the quality of birth that is the diverse birth problems coming out of the, the, uh, for the baby.

[00:16:44] There's something called hypoxia. What happens is the baby's brain get starved for oxygen, uh, under certain conditions. And. The creatine levels because the brain is creaking. It's very neuroprotective, especially in hypoxic States, creating is again [00:17:00] associated with a successful birth and a kid without brain damage.

[00:17:04] So even pre-birth, you know, not only does it save babies that are alive that may have this, this genetic deficiency, it could also be a great value, uh, to both, uh, to both women and unborn kids and a healthy, successful birth. So that was a paper that just came out, which what I tend to do is I'll take like an older post and update it versus writing a new one.

[00:17:24] Right. So I like to just saw the creaking saves baby. When I update it as an older one, which I updated with that new, that new paper. That's how I sort of liked to just fill them up. So yeah, talking

[00:17:33] Carl Lanore: [00:17:33] about thinking about neuroprotection. So, um, my mom, when she was alive, she, she had a stroke and this was about.

[00:17:42] I think I was doing the show already. So it was about 15, 16 years ago, maybe around there. Yeah. And I went out to take care of her. She couldn't talk, you know, she had some, uh, uh, facial paralysis that was typical of a stroke. And I had found that really good study that showed that, uh, taking creatine monohydrate [00:18:00] at two and a half to five grams a day helped resolve a stroke faster.

[00:18:04] Yeah. I went to her neurologist and I said, can I do this? He said, sure. And I just, I got to know he was when I walked in with the study, I walked in with this study because I'm just a lot of times they just don't do it. You gave her a, uh, a protein drink every day. And I put two to a two and a half grams of creatine in it twice a day.

[00:18:26] And she came back from that stroke faster. Uh, then she would have, and he said that she, she had, she had no symptoms after that. I have the stroke, it all went away and he said it to me. He said, you know, I really think that creatine did something for, cause she was already in her late seventies at this point in time.

[00:18:42] Will Brink: [00:18:42] Well, that's fantastic. Fantastic. I mean, because you would not believe how many people I get contacted by, uh, that say, you know, say so where my mother had a stroke, I'd like to give her creatine or my kid had a TBI and football. I'd like to give him creatine. And doctor says, no. Doc, you know, and I say, look, take these studies and show them.

[00:18:59] And they [00:19:00] still say no. And to this day, we're talking 20, 21. We're not talking 15 years ago. And it happens all the time. It just blows my mind. You know, so I'm glad it's wonderful that, that you're at least, you know, neurologist was open to it. Just, uh,

[00:19:13] Carl Lanore: [00:19:13] well, that's a rock. Robert Thompson is saying, he said my cardiologist advised me against taking creatine and all supplements just because, so, um,

[00:19:23] Will Brink: [00:19:23] just because he didn't learn anything about them in medical school

[00:19:26] Carl Lanore: [00:19:26] and doctors will say no to cover their ass.

[00:19:30] Because if they say, yes, there's potential liability, they say, no, there's no liability. Perfect. Yes. And attorneys, he said natural path scheduled a renal consult just because I was taking Korea teams. And, and he does go on to say his bun levels. Well elevated, but she knows I take creatine. Would creatine have any effect on bun levels?

[00:19:53] I didn't think it would. No.

[00:19:54] Will Brink: [00:19:54] No, not, uh, yeah. Creatine would affect creatinine level, right? The bun, [00:20:00] the bun levels way to be more likely, um, uh, elevated by a higher protein diets and a weightlifting along with, uh, LDH, I believe. And they keep changing the name of these dammit. The reason I'm guessing. Cause they keep changing the name of these liver enzymes.

[00:20:15] But, uh, I believe it was LDH is another one that will be raised by will be, can be raised by a resistance training. I have not seen any studies with

[00:20:22] Carl Lanore: [00:20:22] balm just for the record. Anybody who's worried about getting, um, um, uh, what is it? Rhabdomyolysis? Creatinine is not an indicator of rhabdo. Myoglobin is. And doctors don't know this and you'll see your creatinine levels getting high.

[00:20:38] And they'll say, Oh, you know, you're a weightlifter. You're, you're going to get rhabdo. And they need to look at myoglobin. Creatinine has nothing to do with rhabdo and doctors don't know this. And it's really sad because there's a lot of guys that telling, Hey, No more creatine, no more working out because you're, you're on the borderline of getting rhabdo.

[00:20:57] And the reality is you're not. So you can tell you that

[00:21:01] [00:21:00] Will Brink: [00:21:01] you'd have to do enzyme. You'd have to look at enzymes for rhabdo, but even creatinine is not even an indicator of liver of a kidney failure, which again, you would expect most doctors would know that, but it's not. Uh, it it's it's it's um, now of course you wouldn't want to ignore high creatinine level.

[00:21:15] I would never tell him what, just do a soft screw it, you know, ignore it. Yeah. Uh, always, you know, if the there's about 10% of people that can get elevated creatinine from Creotine, uh, and we'll always tell them to do is just take a few weeks off hydrate and get retested. And it always comes back normal.

[00:21:31] I've never had one person come back. It was still high. If it still comes back high, then you should definitely go and see what's going on and get a GFR test and all that. But a high creatinine level is not an indicator or a cause. Should I say a cause of, of a kidney? Can you tell her anything like that?

[00:21:49] Carl Lanore: [00:21:49] says herring. Was that the fish you were thinking about? Thank you.

[00:21:52] Will Brink: [00:21:52] Yes, Sharon. I love her.

[00:21:54] Carl Lanore: [00:21:54] Gilliam. Oh my God. Well, my father used to get the Vita herring. It's like in a cream sauce. [00:22:00] Right? Matter of fact,

[00:22:01] Will Brink: [00:22:01] my grandma, my grandmother used to get the pickled

[00:22:03] Carl Lanore: [00:22:03] herring, which I did. Yeah. I loved that too. That was great.

[00:22:05] Around, around, around the holidays, they would have that stuff out. I love that stuff. That was not one of my favorites. So homocysteine is a, is a independent marker for. Arthrosclerosis. Uh, it's an inflammatory marker and I read once and you correct me now, I'm asking you this question. I read once that if you take creatine, your homocysteine levels go down because homocysteine is actually produced when your body makes Creotine out of these other amino acids.

[00:22:30] Yes.

[00:22:31] Will Brink: [00:22:31] Uh, creatine can drop homocysteine dramatically, homocysteine Ashley, but homocysteine high homocysteine levels are an indicator of, of poor methylation, uh, lack of methyl groups. And Korea team, the production of creeping in the body is the most intensive use of methyl groups that you have. So if you're taking Creotine externally, you don't, you free up all these methyl groups to go do all these other beneficial things.

[00:22:56] So yeah, help me assist you naturally is usually an indicator of a meth [00:23:00] methylation methylation. Again has been shown recent data has been shown to be completely indicator are correlated with aging. Uh, how well you methalate things is a very key part of aging. Whether your body says methylene methylation is a big deal.

[00:23:14] B12. Uh, but it's become, it's become, uh, right up there, um, with a lot of other, uh, uh, aging indicators, whether you're properly methylating so yeah, you can, you can lower homocysteine quite

[00:23:25] Carl Lanore: [00:23:25] dramatically do that. Then the liver has the ability to use those resources to do other things. Yeah. Yeah. Now you've

[00:23:31] Will Brink: [00:23:31] will free up all these methyl groups that normally would have been used to produce Creotine because you have to go for the guano decent guano guano, a data asset.

[00:23:38] I think I'm pronouncing it right. That's the precursor precursor to creatine. You attach a methyl group, you get creative. So, if you don't have to make that step, you're freeing up all these methyl groups to go to all these wonderful anti-aging things or at least aging supportive things. Okay. Are

[00:23:52] Carl Lanore: [00:23:52] there any other things that can enhance methylation or their donors to the methyl groups that you could take?

[00:23:57] Like I know methyl cobalamine is supposed to be better because [00:24:00] it's already methylated, so you're not taxing the liver to make it that way, but are there things you can take that will, that will increase your ability to methylate?

[00:24:09] Will Brink: [00:24:09] You absolutely are. And if you, I can even go, I have an article, well, not an article, but even at a formula I'm trying to develop that basically is a creatine plus methyl groups.

[00:24:19] And I could look it up, but, um, there's also, yeah, there's about half a dozen different things that are very helpful to methylation B12, as you said. Uh, I I'm trying to remember of creating is another one. That's kind of the big one, but I can't, I'm trying to remember, um, Okay,

[00:24:38] Carl Lanore: [00:24:38] another show. Let's save that for a show.

[00:24:41] Enhance methylation. That could be a show by itself. But, um, for the record, I just want to repeat this again. If you're a guy and your doctor says your homocysteine levels are too high and he recommends you take B12 abandoned the B12 take, take B12. It's okay. But just take five grams of creatine every day, day.

[00:24:57] And next time you go back, go, Oh my God, your homocysteine [00:25:00] levels of less than 1.1. You know, it's like, it's like magic. It really is. I want to take a quick commercial break. When we come back, I'd like to have you tell us what other new and exciting things you've learned about Creotine lately that are ideally suited for a healthy aging of, of, uh, adults.

[00:25:20] Will Brink: [00:25:20] How's that right? Well, and I'll, and I'll have the list of methylators up too, but I'll, I'll pull those up because I, now I, of course, I want to get back to it. One thing about aging, as you know, Carl, no matter how much neuro stuff you take. Your recall just is not what it used to be. I used to be a walking computer of pulling it up, studies authors when the study was published, so on and so forth.

[00:25:41] And, uh, it definitely not that that, that speedy recall is not what it was. So

[00:25:46] Carl Lanore: [00:25:46] it's interesting you say that, make sure we talk about this on the other side of the break. Okay. Yeah. Okay. Stay tuned. We'll be right back with more we'll break States.

[00:25:59] Will Brink: [00:25:59] Did you

[00:26:00] [00:25:59] Carl Lanore: [00:25:59] notice how short the commercial was? Yeah, we've shortened up our commercial breaks. Yeah. It was my director of communications, Natalie Kopecki, your turbines that our commercial breaks too long. So we're shortening them up so that we get back on the air faster. Okay. Talking about memory.

[00:26:19] Will Brink: [00:26:19] All right.

[00:26:19] Before it, before we go, I looked it up quickly during the break. So, uh, betaine HCL, vitamin B12, vitamin B6, folic acid. Coleen and CDP calling appear to be, and creating of course are appear to be the cream, the, the core methylator methylating nutrients to take as far as,

[00:26:40] Carl Lanore: [00:26:40] so are you going to come out with a product that has that we'll add in it?

[00:26:43] Will Brink: [00:26:43] Yes. And I have one other, it's not secret ingredient, but I have one ingredient that I haven't, I haven't mentioned that well, increase brain creating. Uh, it's important to note that the brain typically because of the blood-brain barrier is very resistant to allowing things through and [00:27:00] creating another one of them.

[00:27:01] Uh, creatine, the normal doses we take in are three to five grams per day. Doesn't raise brain creatine, as much as we'd like, it seems to take, you need more like 10 grams or so, um, to really bring the bodies, the body tissue saturate at that three to five grams, but brain Creotine does not get elevated as much as we'd like.

[00:27:19] And, uh, I have, um, I'm after I come out with, uh, alpha Joe, um, you know, maybe the next product, um, I'm talking to a company right now. That's interested in it, but, um, that's difficult, you know, I do consulting work and R and D for different companies and charter and harder these days to, uh, you know, to get a good product.

[00:27:36] So it's just, again, one reason I decided to come out with my own damn, you know, formula at this point, but yeah, so that, that would be in my, my basic, uh, methylating uh, product.

[00:27:46] Carl Lanore: [00:27:46] Does creatine have an effect directly on M.

[00:27:50] Will Brink: [00:27:50] Um, it's a good question. I'm trying to think. I don't directly, I don't think directly it [00:28:00] does.

[00:28:00] I mean, I believe indirectly it does because your workout, your workout harder, or you increased protein, synthetic rates, uh, and so forth. But you know, that's a good question, which I probably should look into. I haven't, to be honest with you. As important as, as creating is in terms of things like mTOR and proteins that are great.

[00:28:16] I actually spend most of my time again, looking at the anti-aging aspects of it, you know, it's like, so I, I guess sort of in that. Can it gain muscle lose. I already know what makes muscle or know what's good for sarcopenia, you know, all that. So to me, that's kind of like, okay, it does this thing. I know it does this thing.

[00:28:31] And now I'm more interested in these other things. I'm still trying to elucidate I E mood and anti-aging and brain health. So I actually haven't looked into that one, but it's

[00:28:39] Carl Lanore: [00:28:39] a good question. The reason I asked you is we did a show a couple, three weeks ago. And one of the things that kind of was, uh, discussed in the show that I didn't know was that M tour's responsible for memory formation.

[00:28:50] Hmm. Um, so memories are basically, um, folded proteins, like, like, like peptides, if you will. [00:29:00] And so when you make a memory, this protein has a syntax and it has, you know, it has, um, different amino acids in different places. It has a meaning and that's put away in your brain. When you recall, uh, a memory you're basically taking that protein out of where it was, you're unfolding, it, you're reading it, but then it requires M Tor to refold it and put it back.

[00:29:26] Interesting. And so, you know, th there's this whole, there's this whole, uh, crush em tour because it ages you faster bullshit on today. Um, and, you know, look, I, I take rap myosin once a week, six milligrams once a week. Right. Um, but I am not like a Metformin guy. I'm not like somebody who would just want, Oh, I got to stop doing anything that turns on M talk, cause I'm going to live forever because it not only will you not live forever, but you'll be cripple the longer you live.

[00:29:53] But more importantly, you're going to have, you're going to end up with problems with your memory. Like, so that's why, when you said about memory and us getting [00:30:00] older, do you think that chance there's a chance that Korea team could correct some of the, uh, The inhibition to be anabolic and actually could help you save memory.

[00:30:13] Will Brink: [00:30:13] Well, I mean, studies on the brain, I mean, have suggested that in that there has been, I don't know about recall, but there has been studies again with creatine showing improved memory, as far as spatial memory, uh, reaction times, that type of thing. So. In leading in that direction, it sounds, you know, like positive.

[00:30:32] Yeah. I mean, the guy just there's different types of memory. I was just the long-term short-term. Um, you know, recall and short-term is the one that, you know, as you get older, you have trouble with, I don't have trouble in Raja. It's the short-term somebody asks me a question, you know, I'll just blank and go shit, you know?

[00:30:45] And it stopped right there

[00:30:47] Carl Lanore: [00:30:47] earlier when I was trying to think of homocysteine, I kept thinking, I kept thinking of N-acetylcysteine. I'm like, no, that's not what I want.

[00:30:52] Will Brink: [00:30:52] Well, macro, so macro just wasn't coming. You said tried. And I should've said I should've been macro, you know, 10 years ago or 20 years ago, but you know, it's a good question.

[00:30:58] We do know though, there [00:31:00] has, there have definitely been studies that are suggestive of yes. Uh, you know, the brain is such an energy intensive organ. It's the most energy intensive Oregon. It uses up most of your energy, most of your glucose. And it's very sensitive to any changes in energy that, uh, to, to reduce that energy levels on a cellular level is definitely going to reduce, you know, um, mental acuity and recall, and mood and all that.

[00:31:22] So, uh, anything that I think improves that, but it's not it's I don't think. And it's a good question I might have to look at is I don't think it's really working on the. The mentor level, but it doesn't mean again that, you know, there's, there's no individual systems. I mean, it's the longer you're in the longer you're in science long, you look at this along, you realize there is no such thing as an isolated system, zero and in the medical, in the, in the science world and in the, the Western medical world, you know, scientists are taught again to, to isolate systems and systems in isolation.

[00:31:51] And that has led us to, to ignore. The fact that they're all working together all the time. There is no isolated system.

[00:31:58] Carl Lanore: [00:31:58] In fact, in fact, that's a, that's an [00:32:00] insult to the complexity of the human body.

[00:32:02] Will Brink: [00:32:02] It's like stupid, you know, stupid. And, and I think, again, I think, I think we're getting a little better about it now.

[00:32:08] Eastern Eastern medicine is kind of the opposite in that they see that they see the body as a whole and the system as a whole. And they sort of almost go too far in that direction where it's like, if it works, it works. We don't care how it works. Whereas on the West coast, the West, what do Western medicine.

[00:32:23] W whether it works or not, we got to know how it works. We got to go find them the pathway in the system. Where's the East. So obviously the balance is somewhere in the middle of great, you know, the middle part there, where obviously, if something works, you gotta know why it works. Right. I mean, the East coming in Eastern floss, they don't care.

[00:32:36] As long as it works, it works. We don't care how it works. So I I'm sort of in the middle there, you know, if something works, I want to know how it works. And because that four I can eat, I can measure maybe make it work better. Uh, maybe I can enhance it. Maybe I can. Reduce the negatives of it. But yeah. So in the, in the, you know, when I went to school and stuff, I mean, we were just looking at isolated, isolated, um, pathways, constantly, uh, and very few people, even the [00:33:00] middle, many medical doctors that I know and work with, um, have, are able to make that leap, you know, outside of this, this one pathway that they know, or they study or whatever to, you know, say, well, how does it, how does it interplay with X, Y or whatever?

[00:33:11] And a lot of times. They just can't do it, you know, at that time that takes a certain mental structure to do too.

[00:33:18] Carl Lanore: [00:33:18] When, when you and I were young bodybuilder types, uh, we used to take our creatine with, um, some dextrose, uh, generally like 60 to 80 grams of dextrose, maybe 40 to 60 grams of whey protein and a hundred to 200 milligrams of our alpha-lipoic acid.

[00:33:37] And it was postulated back then that our Allah could enhance muscle uptake of Korea team because it may have been an insulin mimetic. And now we know it's not, it's more of a glucose clearing, uh, disposal effect more than anything else. Yeah.

[00:33:55] Will Brink: [00:33:55] Yeah. I think it's a CD four. I think it an improved CD four, um, up,

[00:34:00] [00:34:00] Carl Lanore: [00:34:00] up here.

[00:34:00] Right. So do you, so w where are you with, uh, with taking creatine with, uh, our ally.

[00:34:06] Will Brink: [00:34:06] I think it's still worth doing. I just, I actually was just seeing this funny thing about ALA is it that the data, again, sort of has been around for a long time. It will be data that makes this stuff look like miracle stuff, and then it sort of fades away for awhile.

[00:34:18] It seems to be making a little bit of a comeback. Again, there was a recent study on L ALA showing, uh, some, some benefit to that.

[00:34:25] Carl Lanore: [00:34:25] I did. I interviewed the author. Yeah. Yeah. I know it was targeted to, to visceral fat loss. That was the interesting puppet

[00:34:35] Will Brink: [00:34:35] it. So it seems to be kind of making a comeback problem with, I mean, there's probably a couple of problems.

[00:34:39] ALA one of them is just wickedly expensive, you know? Um, and I think I, I try to tell people it's only so many things we can take. Right. I mean, I take more somethings than most people do. Um, all is good for you. It's it's dad. They use it for peripheral neuropathy and stuff in, in other countries in European countries and stuff.

[00:34:57] Uh, it's a very good antioxidant. [00:35:00] Um, so I'm pro ALA. I don't know if it's worth push comes to shove for the money you're spending. Is it worth adding to create a team there? You know, that's one of those, how many things can you take? How many things do you want to take? How much money do you want to spend?

[00:35:12] I kind of, I sort of break things down into, you know, how good is the data, um, um, how effective is it? What does it cost and all that. So as you sort of check off those boxes, It's not really on the, on the worst side, I guess if that makes sense. You don't care how many pills you got to take and what you want to spend yet.

[00:35:30] I,

[00:35:31] Carl Lanore: [00:35:31] we have a sponsor and I got to do a shameless plug here. Yeah. So we have a sponsor called pure nootropics and they just put this together just for my audience. It stabilized our ally. It's bound to sodium and they are like the generic approach to supplements. Uh, and so they actually offer my audience a 30% discount on this already really cheap form of our alphabet 250 milligram caps is 60 of them.

[00:35:57] And if you go to SHR [00:36:00] network.biz/pure and use the code. S H R 30, you can actually get a stabilized form of our Allah really cheap, and I'm going to start using it because of the visceral fat component of it. Uh, that, that study, in fact, that's study. I think it was a show 26, 80 or 26 Oh eight that study, uh, prompted them to put this together for your audience.

[00:36:22] So

[00:36:22] Will Brink: [00:36:22] it's out there. I also, yeah, there's interesting studies also on, uh, different isomers of ALA, too. And there's that. And actually I was thinking of getting back to taking it also because my blood sugar is starting to, again, as we age, you know, our blood sugar starts to work. It starts to good.  started to finally climb up and I'm 55 and it's finally just starting this last year or so to go a little higher than I'd like it to be.

[00:36:46] And 55,

[00:36:47] Carl Lanore: [00:36:47] man, I'm older than you. I'm 62. Yeah, no, I mean, I'm always surprised to hear people's ages because it's just, I don't have any perspective. I don't have any perspective on age.

[00:36:58] Will Brink: [00:36:58] That's the thing. No, I don't either. [00:37:00] I'm 18 in my head. I know I'm 18 in my head. And to me, the nineties were like yesterday.

[00:37:05] I still can't believe how, when I talk about nineties and people look at me like, wow, that's that was so long ago to me. The nineties were, I don't know. It just doesn't, you know, it doesn't feel that long ago, but I have, I have, I have started to notice, like I say, my blood sugar is starting to go up a little bit.

[00:37:18] Uh, which, you know, again, as we get older, our tissues become a little less sensitive in the, you know, it's only so much you can do about that until you need to like add something in or up your off your exercise, your lower, whatever you gotta do. But I actually was just thinking about getting that back into my diet, uh, more for the, the, the, uh, uh, glucose disposal.

[00:37:34] Carl Lanore: [00:37:34] Try it, try this, uh, that stabilize form. It's bounty. Oh sodium. It's supposed to be a superior form. You don't have to take as much of it. Um, so bear wants to know. And there's another question I'll get up here too, before the break bell wants to know on that note, are there other supplements that have a synergistic effect with Korea team?

[00:37:50] Where are you on things like beta alanine and creatine stack together?

[00:37:55] Will Brink: [00:37:55] Um, well, there's different. There's still such different questions. There's there would be like, there's one of the [00:38:00] synergism that is two things that actually are greater than the sum of their parts are greater together. Right. I think beta Ellenine and creating AR should be a great combination.

[00:38:08] I don't know if there's synergism in the classic sense, but is there additional benefit, which is different than synergism? Probably. Yeah, I think that's one of the beta Alanon definitely looks like one of those worth. Oh, I've always put that on. And there are some. Uh, anti-aging benefits ally. And to, you know, do you remember all the, the anti-aging people are real big on carnosine.

[00:38:26] Right. Um, but for some reason they won't take beta Alanon. So what is beta? I mean, carnosine is just beta alanine in his study. And when you swallow carnosine you break apart, it breaks apart, goes back together. I've been trying to get anti-aging companies like I do life, you know, I do work for the life extension and stuff.

[00:38:43] Um, you know, and they are big on carnosine, but they just, I just

[00:38:46] Carl Lanore: [00:38:46] can't get it. And the irony is there's two really well done studies that show that beta alanine is the limiting factor in your body producing carnosine

[00:38:56] Will Brink: [00:38:56] well, yeah, well, it's similar to that. Maybe they made them in the same studies, but there [00:39:00] are studies that show that beta alanine increases tissue.

[00:39:02] Carnosine better than carnosine

[00:39:05] Carl Lanore: [00:39:05] for Shipt sake. Yeah, I know. Right. I know. What do you think, do you think it's because we're bodybuilders and they're like, no, we don't want that. Um, but you know, that's the body, the thing

[00:39:14] Will Brink: [00:39:14] about anti-aging types. Well, bodybuilders are pretty neurotic too, but anti-aging types take, but OCD, neuroses thing.

[00:39:19] Don't hold other levels. Yeah, no, you're right. There was, there was one study that showed beta alanine, uh, caused Turing depletion in cats. It does. It does. Right. Well, that'd be cats. Cats. Don't make taurine. We do. It's a

[00:39:33] Carl Lanore: [00:39:33] non-issue and plus that's easy to solve. Just supplement with taurine. Taurine is another great immunoassay.

[00:39:39] What

[00:39:39] Will Brink: [00:39:39] the hell? Right? What a revelation. That is. That's what I do. So again, I proposed a product which was based a beta beta alanine, plus taurine, if you're so damn worried about it anyway, but yes, you're right. So yeah. Taurine is dirt cheap. It's good for you. I actually, I go to touring the most underrated amino acid of the mall.

[00:39:58] It really is an underwrite people. [00:40:00] Real that's a whole other conversation,

[00:40:01] Carl Lanore: [00:40:01] hard protective. It does so many good things. Yeah, it really does.  wants to know does cooking fish, meat, pork reduce the creatine.

[00:40:11] Will Brink: [00:40:11] Good question. I don't have a good answer to that one. It's pretty Hardy stuff. I don't think you're going to damage it, but you know what?

[00:40:19] That's a good question. I don't know. I never looked into that one. I don't, I don't think that the, the Korea team. Content changes substantially upon cooking, but that's a good, it's a good question. I honestly don't know. I don't know if it's actually ever been studied, to be honest with you. I guess I, and I, and I have to say the reason I'm not that interested.

[00:40:39] I don't have a great answer just because of my view supplement. You supplement. So I don't worry about it. I mean, so like again, we can only look at worry about so much stuff, you know, and so whatever I can put away and not worry about and, and, and, and overtake my brain on stuff, it's like, this is why I don't know dates and holidays and stuff, because I only

[00:40:55] Carl Lanore: [00:40:55] got to find something to find that somewhere, you know, who was like that, I just don't care.

[00:41:00] [00:41:00] Einstein. He couldn't remember his own phone number and people used to joke with them. You you're the smartest man in the world. You can't remember your, he says, cause I can find it in a book somewhere. I don't have to remember

[00:41:09] Will Brink: [00:41:09] it. I can, he didn't know my own mother's birthday nor my own father's birthday.

[00:41:13] I've been reminded of my own birthday on my birthday and so on and so forth. I don't give a shit about dates. I mean, so to me, I can only, you know, I only want to fill my brain with so much stuff. Um, and so like, say that question to me. To get the amount of beef and herring and lamb. And so if you've got to eat every day to get three to five grams of creatine is a lot, I could do the calculations, but it's more than you want to eat.

[00:41:38] It's dirt cheap. It's safe. Supplement, move on with other stuff to worry about. That would be my answer to that question. I hope it doesn't offend anybody, but that would be the way to answer

[00:41:46] Carl Lanore: [00:41:46] that question. You know, commercial break, we'll be right back with more, stay tuned, share the show. Please also share our shows.

[00:41:52] You help people, especially vegans stay tuned. Ashley,

[00:41:58] Will Brink: [00:41:58] welcome back.

[00:42:00] [00:42:00] Carl Lanore: [00:42:00] You know what I just realized though, recently I've been talking about, I got a couple of the business ventures that I'm working on and I thought, you know, I would love this show to go on someday. But maybe not me hosting it. And the hardest part for me has been, how do I find somebody to host this show?

[00:42:16] You could host a show, just the thought, just a thought. I'm just, I'm just saying that

[00:42:22] Will Brink: [00:42:22] I did it. I did a podcast myself, uh, was, uh, Oh, it was a from years ago. And, uh, I got about 10 of them. I have to say. And you know, the problem of course is just especially back then. It was just, it's just a lot of work. I mean, I enjoyed it.

[00:42:34] I had some, I had some good shows. Uh, and I enjoyed the process. It's just, it's always a lot of damn work, you know, there's anything, anything as, you know, like doing what we're doing now, it takes a lot of prep, you know? And so there's might be the hour, we're doing a show or whatever, but as you know, it does take a lot of prep.

[00:42:50] And I, once I start getting a couple of the projects I need to get out of the way, one of them is alpha Joe coffee. Another one is I have the 20, 20 and 2021. My two focuses were [00:43:00] to get my fiction stuff off the ground, which is doing really well. Right. Cause I do fiction. A lot of people will know that. Uh, and the alpha Joe coffee.

[00:43:07] And so once those two were kind of like running them, doing their own thing, um, we'll be open to other projects and doing

[00:43:12] Carl Lanore: [00:43:12] other things. Yeah, no, absolutely. Um, so Gerard  wants to know creatine before after workouts. Right? We always take told to take it after workouts because yeah, but that's not true, is it?

[00:43:25] Will Brink: [00:43:25] No, it doesn't. It doesn't matter. Uh, creating there's no real nothing to create creatine as a, as a, as a chronic effect. It's a tissue level effect. So once you've gotten to the tissue levels, timing doesn't matter. Uh, Jose Antonio did a study, a small study that found that taking it after workouts was just marginally better.

[00:43:44] I mean, just like a point above statistical significance. Uh, but for the most part, I mean, that's, that's the supply just, you might as well take it then any way. If you're going to take it during the day. Put it into your protein drink. But as far as the fact that doesn't matter, uh, but you say creatine is not like a stimulant.

[00:43:58] It doesn't do anything at a, at a, [00:44:00] at a window. You take it creating as a chronic effect of increasing tissue creating levels. So that effect is the same.

[00:44:06] Carl Lanore: [00:44:06] Although when I do use it in coffee, which I do, and I have to be honest, I learned this from you a long time ago, you started talking about putting creatine in coffee years

[00:44:16] Will Brink: [00:44:16] ago.

[00:44:16] Yeah, 10 years. Plus I've been giving away this formula to people which ended up being, uh, alpha Jo or ended up being bomb-proof, which is

[00:44:23] Carl Lanore: [00:44:23] now alphabet. Right? And so I started putting creatine in my coffee. Now, maybe it is just a placebo, but I feel like it definitely has a brain effect when you combine it with a little caffeine.

[00:44:36] Am I wrong about that?

[00:44:37] Will Brink: [00:44:37] Well, again, the data isn't there to put on my scientist brain. I'm going to say the studies specific to combining them is not there. But it makes perfect sense. Um, hence why I, you know, why I, why I put it in my own formula that there's definitely cognitive effects of creating that we have good studies on again, whether there's a combined effect of the tumor synergistic effect.

[00:44:58] I don't know. There is a [00:45:00] synergistic effect of caffeine plus Coca-Cola, which is in my formula. That's there they're actually more effective together than they are separately. What do we mean by, by synergism, but yeah, um, I, it makes perfect sense to me. We put it in your coffee. So

[00:45:13] Carl Lanore: [00:45:13] let's, let's focus on let's focus on the moon food and, and brain effects to wrap up this portion of the interview.

[00:45:19] And then later Will's going to share some things with us that he's really never shared with anybody else. And I'm excited to talk to him about this. So I remember the military did a study. Uh, they did, they took some soldiers that had to work in overnight and they gave one group of placebo on one group.

[00:45:35] They gave five grams of. Uh, Creotine and the group that got the creatine had no problems with wakefulness and, and, and alertness or anything like that. And the other group, obviously working in overnight, they'd kind of were slower moving and a little tired, and some guys even fell asleep at their post.

[00:45:53] So how does that w that re study way into the, um, [00:46:00] mood elevating effects? Cause we know if you're alert, you're feeling good, you know, what, what other research points

[00:46:05] Will Brink: [00:46:05] at that? I'll give you a more, even a more interesting military study, but one of my favorites is, uh, with creating. So they took a, they took a group of Navy seals, uh, and during winter warfare training and one group got created and got five grams.

[00:46:21] My thing was five or 10 grams. The other group did not. They gave them, uh, um, uh, mental tasks, various tests, you know, recall imaging, uh, that type of thing. And they put them out into Arctic cold and the. Brought them back and retested them. Well, only the ones that had the creatine test exactly as baseline, same baseline.

[00:46:40] The ones that had, did not have creatine as expected when you go out in the cold, uh, we're way off we're way off baseline. Because when you're out in the cold, again, your, your neurotransmitters, your energy levels, your cellular energy love your brain tissue levels are, are used up. And so even these guys that are top of their game, obviously they're, they're very smart guys.

[00:46:59] They're [00:47:00] sharp. They're on it. Uh, after winter warfare training, Um, given creatine, they were actually able to do the same mental acuity task as they were at baseline. So that one to me is even more telling as far as like acute stress, you know, it's an actual, it's an actual sprain stress type nutrient.

[00:47:15] Carl Lanore: [00:47:15] What about, um, the fact that some body builders early on believed that continuing to take creatine during a cutting phase would not allow them to lose as much weight because it's shifted substrate, a preference towards glucose. Do you remember that, that going around in the bodybuilding community maybe 10, 15

[00:47:35] Will Brink: [00:47:35] years ago?

[00:47:36] I mean, a lot of them, the only ones I've ever heard that bodybuilder stopped using, creating pre contest was the water. And, you know, it's the water, but that's because again, they were thinking that the water was under the skin subcutaneous and it's not it's intramuscular. And there's no reason to stop taking creatine pre contests.

[00:47:52] Um, and there's Ivy and there's pictures of a bunch of guys that I worked with, you know, back in the day where, you know, shredded, but the only time I ever, I never heard of any substrate. So [00:48:00] the only thing they used to stay with while it holds water and I want to get rid of the water.

[00:48:03] Carl Lanore: [00:48:03] Okay. Well, is there a possibility, is there a possibility to take it too much and it spills over out of muscle and gets into sub Q tissue.

[00:48:12] I

[00:48:12] Will Brink: [00:48:12] thought I, the studies and there's been a handful of them have, have always shown that these, the compartment that is the water compartments don't change. That is the same amount of water as far as ratio is the same as it was under the skin as it is. So, no, it shouldn't, it shouldn't be no spillover.

[00:48:27] I've never seen anything like that. Um, and there has been I'll bet three or four studies that have looked at that. Maybe look, you know, doing pretty good. They've even done it with radio labeled water, which is really sophisticated stuff and found like, say the, the uptake is almost all intracellular.

[00:48:39] There's very little additional water subcute so the interest should be no now. All right, so don't do 20 grand. Let me get to simplify this without taking the science of wait a minute. You know, if you're worried about don't do 20 grams of creatine, you know, stick to your, you know, your, your five to 10 I'm out, but there shouldn't be any preserve muscle

[00:48:56] Carl Lanore: [00:48:56] science shows that.

[00:48:57] If you do five grams a day for like a [00:49:00] month, you get the same tissue loading is if you do the 20 grams for five days. Yeah.

[00:49:05] Will Brink: [00:49:05] That's why to slow it. Loading the loading phases is out the window. Nobody does loading pages anymore, right? That's that's

[00:49:10] Carl Lanore: [00:49:10] that's that's all new. I'm thinking that Dawn Mike Fenty Sheck is Dawn, not Mike.

[00:49:16] They must share an account. A lime ate my muscles, getting integrative treatment, praying to get healing. I'm wondering if she's asking. If, uh, there may be a place for, um, muscle degenerative diseases like Lyme disease, uh, or even fibromyalgia. Is there a place for creating,

[00:49:37] Will Brink: [00:49:37] uh, now you have brought up a very important point that I even forgot because I tell you there's so many papers that come out.

[00:49:45] That I, I can't even keep track of. And she is part of a very important point that there was a, just a big paper out that found the creating wasn't was a benefit in what they call a post-viral syndrome. Uh, obviously specific now, but obviously it's direct a little bit of COVID. However, [00:50:00] again, they find that people that have been exposed to viruses, show cellular energy, dysregulation, and weather, whatever that may be, whatever virus that may be.

[00:50:08] And so she is, that's a really good point. I posted that paper on my Facebook page. So the answer is probably yes. Um, there, it does appear to be a benefit in what they say. There's a general syndrome. He posted viral syndrome. I mean, a lot of people have experienced this, right? You've you've had the flu or whatever, and all that, the acute symptoms may be gone.

[00:50:26] But for me, you're sluggish as hell. Yeah. You're just tired. And that is what may be now for some people that never goes away. And that's that, that, that brain fog that's tiredness. That's slowness now. And Lyme disease is famous for that. Uh, as, as of course did some of them, um, fibromyalgia's another one.

[00:50:44] They're not, nobody's no, sh they're not sure if I'm around is, is a viral, you know, come from viral exposure, but there's, there's theories on that. But, uh, yes, creating could be and should be of considerable benefit too. Uh, what they call like say viral post viral syndrome. And if you have [00:51:00] just again, uh, chronic fatigue is another one.

[00:51:02] Nobody knows where it comes from. One of the main theories of chronic fatigue is that it's a viral. If you've been exposed to a virus at some point, um, and they do find like Epstein-Barr and stuff is very common, uh, to show up with people with chronic fatigue. So, yeah. Great question. And like I said, I'm glad you, you brought it up because that's another paper I had just completely forgotten about that.

[00:51:19] I just read that just blew my mind. So

[00:51:21] Carl Lanore: [00:51:21] the mitochondria is exciting. We're we're learning more and more about it. Um, yeah. Does creatine do anything beneficial to mitochondria?

[00:51:31] Will Brink: [00:51:31] Uh, in fact, good question. Uh, there was a study that actually showed that creatine increased mitochondrial production, not just improved the function of my Biogen, but actual biogenesis.

[00:51:44] Yes. Thank you. Yes, actual biogenesis. Now the thing is, when you, when you look at all these different systems, aging, uh, um, brain health mood, Under the hood. I mean, what is the common denominator under all this it's, as you're saying, it's, it's, it's something called [00:52:00] cellular energetics, basically the cell, you, the energy flux, it's called energy flux, the cellular energetics, the synergy status of a cell, all of them is relate is the key.

[00:52:10] I mean, that's like, that's like the bottom line to whether we, whether we get healthy, whether we feel good, whether we, you know, whether we get ill, uh, or not. And you know, if a cell is a world, George's a bundle of cells, right. So if a cell is not producing energy or is putting out some of the, the electron transfer chain, which basically moves electrons is in that argument, in that mitochondrial thing and everything at the end of the day, if I was to like narrow it down to one thing, that's sort of the common denominator.

[00:52:39] All this is is, is cellular energetics, and that's a big area of study. And as you said, mitochondrial health, Um, it's coming because we get older as mitochondria leakage again, where the mitochondria, the leaks electrons, it can't contain them. And so what that does is obviously the cell is not functioning and it either dies.

[00:52:56] You know, it goes,

[00:52:58] well,

[00:52:58] Carl Lanore: [00:52:58] it becomes a senescent

[00:52:59] Will Brink: [00:52:59] cell. [00:53:00] Well, it gives a whole other grade. There's a whole other conversation. Yes. An essence. I'm, I'm big on that one. It's the whole anti-aging thing. It's something I've been looking into because I'm getting older.

[00:53:07] Carl Lanore: [00:53:07] Yeah, I know, right. I focus focuses have changed haven't they will.

[00:53:11] Will Brink: [00:53:11] And I, and I've taken a cellular senescent meds. Uh, I've taken, um, I've tried that. In fact, you're supposed to do them every six months, uh, this akin app. And of course

[00:53:19] Carl Lanore: [00:53:19] it, yeah, I take, uh, I take courses in advice in that, uh, We have a sponsor that has a nice product, but there's

[00:53:24] Will Brink: [00:53:24] a, there's a, there's a drug that you combine with it, uh, called this a 10 average is actually a cancer.

[00:53:29] Carl Lanore: [00:53:29] Well, yeah, it's an, it's a chemo. Right. I pronounce it this Avenue, but yeah,

[00:53:34] Will Brink: [00:53:34] you might be, and you might be, and you might be right. Yeah. But anyway, you're supposed to do that every six months, but yeah. So back to our, our, our question, you said, yeah, so there may be some essence cells. They may go like a pop tonic.

[00:53:43] Of course they're there then there's of course proper links to cancer. So yeah, that is absolutely. And under the hood, Um, I think those, those nutrients that either support the mitochondria cellular respiration or stabilize it, because again, there's also a lot of [00:54:00] issues working in that proton leakage.

[00:54:01] It's called electron leakage is a big deal, but yeah, uh, creatine is an absolutely key, but maybe the key nutrient as far as, as far as, um, uh, biogenesis, as far as, uh, cellular energy,

[00:54:14] Carl Lanore: [00:54:14] it's just so fascinating. So, uh, before we take this break, I want people to stay with me because. Will is going to share some stories that he really hasn't told anybody before and excuse me.

[00:54:24] And it, it arose from a discussion we had before the show. And I said, do people know this story? And he says, no, not really. So we're going to share a little bit. The other thing I want to say is if you are listening to this show right now, regardless of when it is two weeks after the show, and you want to see more of we'll bring on superhuman radio.

[00:54:45] Email me at, on This email address is being protected from spambots. You need JavaScript enabled to view it.. And I will give you a free box of tasty pastries from legendary foods. Yeah, you'll get a free box too. You said, well, you [00:55:00] have to email me and tell me if you should be back on the show. All right. I'll do it. All right. So there you go. This is an easy one. I want to know.

[00:55:06] Do you want we'll back on the show and if you take, if you, regardless of whether you say yes or no, I will send you a free

[00:55:14] Will Brink: [00:55:14] box of taste. I want you to email to say no, but send

[00:55:16] Carl Lanore: [00:55:16] me a free box. Yeah, that's a good way of saying it. Say no, but send me a free box. And if you want, if you want to read, I'll give you those.

[00:55:23] So you can, you can put a hit on them. Um, and if you want to check out more of what will is thinking about and writing about go to bring zone.com today and. Keep an eye out at the website, alpha Joe coffee.com for the single best coffee you'll ever have. Take your coffee to an 11 with alpha Joe coffee.

[00:55:42] We'll be right back with more super radio stick around.

[00:55:55] welcome back. I don't know if you saw the commercial book placard, but I love this thing. [00:56:00] This is my mile storm meteorite. It's a massage ball. It's heated. It has three different levels of vibration. So I use it for everything you hear that I use it on the back of my neck. I use it on sore muscles, but I gave myself a testosterone injection, uh, last week.

[00:56:19] And I went a little too far towards the knee on the quad. And because I put to see season, it was, it was a lot, but that small muscle area, well. I had pain and soreness for two days. And then I thought to myself, I wonder if this would work. I put this thing on it with the heat. And I just rolled around on my naked leg for a while.

[00:56:37] And the next morning the pain was gone. Well,

[00:56:39] Will Brink: [00:56:39] the heat part, especially that's a big

[00:56:41] Carl Lanore: [00:56:41] one. Yeah. Yeah. And this is, this is the greatest invention in the world. I take it with me wherever I go. I put it in the crook of my back. It wakes me up. I put it on the top of my head right before a show and the vibration kind of wakes my

[00:56:52] Will Brink: [00:56:52] brain.

[00:56:53] Is, uh, is that you have to heat it up or do you push a

[00:56:55] Carl Lanore: [00:56:55] battery? It's got, it's got a, it's got a, it's got a vibration setting. Right. And then it's got a [00:57:00] heat setting. You just turn that on and the ball gets

[00:57:01] Will Brink: [00:57:01] hot. Yep. No. I like the heat part. Cause I use like balls and stuff, like a roll on them, but the heat park would be the game because I've got wands and all kinds of stuff.

[00:57:10] But heat is a, there's a huge difference, you know, to, when you go a chiropractor stuff, they put the heat pads on you before they adjust you. It loosens up all the muscles and all that.

[00:57:18] Carl Lanore: [00:57:18] Yeah, I like that. So it's $149, but you can win one of five. We're giving away five to five. Lucky. Listeners. If you go to SHR network.biz/free media, or all you gotta do is enter your email address and you're entered to win.

[00:57:30] So check it out, man. This thing is amazing. So let's get back to so we'll, and I kind of have a similar story, but just at different points in our lives. And we found the physical culture because we kind of were broken a little bit. Talk about how you, why you, why you even, I mean, you, you trained at the Mecca of bodybuilding back in the day when Arnold was there, how did you end up becoming a physical culture as a bodybuilder?

[00:57:54] Will Brink: [00:57:54] Well, I was so here's, I've mentioned this a little bit over the years, but now that I'm older and don't care, but you know, back in the [00:58:00] day, you know, uh, to have any sickness or, or whatever, you know, when you with what's a sign of weakness, right. And even it wasn't your fault, you get hit by a car or whatever.

[00:58:07] So I've never really talked about this. I mean, my friends know, um, and I just, you know, I'm not the kind of person again, we're from Brooklyn, you know, you tough it out. Right. We don't, we don't, we don't wear our problems on our sleeves here. Right, right. So how I got into actually into the whole body going thing.

[00:58:20] I mean, I was lifting weights. I was about 20 years old. I was, I was lifting weights, but I mean, just casually, I was going to college. I was majoring in, um, uh, psych and journalism and I got Hodgkin's disease, like a cancer of the lymph nodes. And, you know, I'm 20 years old. I eat pretty well. You know, I take a multivitamin and I'm like, what the fuck?

[00:58:40] You know what I mean? I thought that's all you had to do not to get sick. Right. And, but I, you know, beyond that, I didn't really know anything. I just knew what everybody knew in the gym. I lifted my weights. That was that. And now I've got Hodgkin's disease and I'm 20 years old. Uh, you know, when I had to get, uh, I had to get treated, I had radiation, um, you know, which, um, reason I've got a of good and people like to make fun of people or say shit [00:59:00] about people and they don't know.

[00:59:01] Anything about their physical people, like make fun of my, now I have pictures from older pictures. I used actually a really big neck that was like my strong body part. Right. But a bunch of nerves were cut when I had the operation. All bunch of nerves were cut and they took out this lymph node. And so I don't have a, I can't really innovate.

[00:59:14] I can't flex. Right. So the treatments and all that, um, you know, the treatments, we don't really mess me up. Um, you know, I had high dose radiation from about here to here. So I have no thyroid. My thought I would do is destroy thyroid. I have a stint in my heart. Um, I never told anybody that, so, uh, what happened from the radiation?

[00:59:35] This, uh, scar tissue built up in my heart. Uh, I've got scar tissue in my lungs. I've got a stent in my heart. Um, what else is wrong with me? That's most of it. Uh, you know, so I mean the radiation, frankly, if I, again, if I had known what I know now, then I wouldn't have done it. I would have taken my chances.

[00:59:52] The, the, the cancer that I had was very much encapsulated in that one lymph node. And they didn't think it went anywhere, but just

[00:59:58] Carl Lanore: [00:59:58] in case, [01:00:00] just

[01:00:00] Will Brink: [01:00:00] in case, just in case we're going to radiate them fuck out of you for the next two months. And I didn't know any better. I'm 20 years old. This is, you know, so when all that was over, um, you know, and I, my health was, was pretty beaten down.

[01:00:13] Um, that's when I really got into the interest of science and health and vitamins. Um, and I was reading an article and, uh, in fact, in muscle and fitness, and it was an interview with Derek Pearson and Sandy Shaw number, Derek isn't Danny Shaw. Yeah. Well, Sandy Shaw had a very rare cancer in her. Uh, it was a salivary canceling, unbelievably rare.

[01:00:34] Right. And he said that she, um, during the radiation treatments she could vitamin C and vitamin E and high doses to avoid being burned. So I did the same thing and the doctor said to me, you know, look, you're going to get really, really burns and your skin's getting red. And I, you know, and I said, well, okay, I'm taking this, taking the C and the EDA to prevent that.

[01:00:57] And you know what? It didn't happen. You didn't get burned. And the doc, [01:01:00] I got a little red, I got a little suntan basically, but I didn't get that red. And the doctor now, of course, what are the doctors tell me, I'd love to

[01:01:07] Carl Lanore: [01:01:07] do. I know I was going to say

[01:01:10] Will Brink: [01:01:10] right. And I'm like, you guys all warned me that I was going to get burnt to shit.

[01:01:13] I'm going to be all red and dying. And so now in retrospect, I wouldn't have done that because in fact, it's not a good, you actually don't want to take high dose antioxidant during treatment, but that's another,

[01:01:23] Carl Lanore: [01:01:23] but the reality, the reality is that you really didn't have anything metastatic going on. So

[01:01:28] Will Brink: [01:01:28] yeah, so.

[01:01:30] Exactly. But had I had, I had, I mean, it could have been a problem.

[01:01:33] Carl Lanore: [01:01:33] You could have promoted the cancer to grow. Right.

[01:01:35] Will Brink: [01:01:35] So for me here I am proof of concept. So no, I have no science background. I'm interested in fitness, like everybody else. Um, I graduated college. I went live with my father for a year to recuperate my health, honestly.

[01:01:46] And then I went back to school, uh, you know, for sciences. I said, you know what, I'm going to go back to school and you know, I'm going to, I'm going to do pre-med. I thought I might be a doctor, but I went and did all the pre-medical sciences. I am then a bunch more. I mean, I've got enough credits to be for two master's degrees.

[01:02:00] [01:01:59] I've gone to four different colleges. One of those eternal pipes who never, I finally finished my day and my one stupid little degree, but I've got enough credits probably for two master's degrees at this point. So what sent me into the really put me in down the rabbit hole of health and fitness and all that was, was that illness that, uh, uh, and I'm still dealing with, like I said, because I've got, you know, I've got scar tissue in my lungs.

[01:02:21] I have to take thyroid meds every day. My thyroid was, you know, destroyed by the

[01:02:25] Carl Lanore: [01:02:25] radiation. And I gotta tell you something, your lifestyle is evidence that it works, that you actually were able to mitigate. Uh, some of the really horrible effects of radiation. So yeah, whenever women have breast cancer and it's the left breast and they get radiation, they all end up with heart problems.

[01:02:46] They all end up Harper because that radiation destroys hard tissue. I am here. I am. I know. That's my point. So obviously physical culture saved your life.

[01:02:55] Will Brink: [01:02:55] Yeah, absolutely. And again, the sad thing about it, nobody told me, nobody [01:03:00] sat me down and said, Hey, you know, you need to keep an eye on your heart because in about, you know, 10 years or whatever, you know, this causes, nobody gives you anything.

[01:03:07] Nobody says anything to you, you know? Yeah. I have to learn this for yourself. I started to have palpitations. And again, as you said, I go in and the doc said, you know, the reason you didn't drop is because if you're in such good shape overall, right. He said, you shouldn't because of the heart, the scar tissue.

[01:03:22] You know that the limited blood that you have going through that once he said you should've fallen over how you drove yourself here. I don't know. He said, but I'm putting it down to your, your, your peripheral cardiovascular system is so healthy that you were eight. You were able to adjust and get yourself here.

[01:03:36] So I go down there and I get a, you know, MRI and all that. And he said, you know, you're, you've got scar tissue. That's closing up. Uh, because of the damage that was done to your heart and we're going to have to put a stent in. So yeah, I've never talked about any of this to anybody. It's fascinating. I, a good handful of my friends that have no knowledge of, uh, of any of this.

[01:03:54] And it's, so again, it's not like say I, I, you know, it, you know, we're old school, I guess we're old school. We're from Brooklyn. [01:04:00] I'm a Northeastern Yankee. I mean, we just, you know, you'd have to ask me or. Um, we don't talk,

[01:04:04] Carl Lanore: [01:04:04] we don't talk. We don't, we don't talk about our problems as a rule.

[01:04:07] Will Brink: [01:04:07] No, no, no. So behind me, on my immediate family, you know, I've never really talked about it now.

[01:04:12] Right. And I have to say that back in the day when you're younger and you're in bodybuilding and that's your bread and butter,

[01:04:18] Carl Lanore: [01:04:18] um, you don't want people to know that you have,

[01:04:21] Will Brink: [01:04:21] you know, at the same thing with animals, right? If an animal gets injured and stuff, they won't, you don't like animals. Don't show it right.

[01:04:26] If your cat or your dog or whatever, it breaks a leg, they'll you notice that you don't show it. Why.

[01:04:32] Carl Lanore: [01:04:32] Because you could eat and they become pray. You're praying. Right. And we, and we spent more time in that world than the last, you know, what, 40, 60,000 years that we spent

[01:04:43] Will Brink: [01:04:43] in this, we think we're above all that stuff, but we're, we're not, we're, we're, you know, we're just barely out of that realm.

[01:04:49] And I think it's, it is the same in the human, uh, in the human realm, that to show weakness of any kind, whether it's your fault or not, it doesn't matter. You're, you're a prey.

[01:04:57] Carl Lanore: [01:04:57] Look, look, look what people used to do with back in the days, [01:05:00] if they had a sickly child, they would hide them because they thought that it would be, it would cast a shadow on all of the family, that there was weakness and frailty in the family.

[01:05:09] Will Brink: [01:05:09] It did, or they kill them or I mean, or whatever. And he used to throw them up, you know, let's get these and throw them over the cliff. But having, having a kid with any sort of a disease, it was not, their fault was, was a sign of a weakness, a poor family bringing. So yeah. These are things I never really talked about, but when people ask me what got you into the health and fitness, you know, what, what, what made you so, so interested in that, that's what, that's, what changed my entire life.

[01:05:35] I was just, you know, I was just, I did weight. I lifted weights. It didn't, but that probably would help me, but I was, I would have gone on to probably be, I don't know what a journalist or whatever, you know, at the time. Right. That's right. So I went down that rabbit hole.

[01:05:46] Carl Lanore: [01:05:46] The break This email address is being protected from spambots. You need JavaScript enabled to view it. to read all of the amazing things that we'll writes about, and you can keep an eye This email address is being protected from spambots. You need JavaScript enabled to view it..

[01:05:56] Take your coffee to an 11. It will be released shortly. So keep an eye on that. [01:06:00] And. If you want more, we'll bring on supreme-a radio. I'll have him on more often. We'll do interviews. He's got fascinating stuff to talk about. He's a wealth of knowledge, highly respected. Uh, I'll have him back on, but you gotta make it happen.

[01:06:14] You have to email me at, on This email address is being protected from spambots. You need JavaScript enabled to view it. and say you want more we'll break and I'll even reward you for taking the time to email me. And I'll send you a free box of tasty pastries. Can't guarantee the flavor, but I'll send you a free box. So that's it. That's it for today's show we'll. Thanks for being here today, brother.

[01:06:34] Thanks Carl. We'll do it again. And uh, that's it for me. I'll see everybody tomorrow with more superhero. Oh, Eddie Gallagher is going to be on the end of this month. Eddie gal,

[01:06:44] Will Brink: [01:06:44] a seal, right? Okay. I thought I was gonna say, is that okay?

[01:06:47] Carl Lanore: [01:06:47] Yeah, absolutely. Yes. So Eddie Gallagher, Eddie Gallagher's coming on. Uh, we're going to talk when he's going to do an episode of, of fathers and sons.

[01:06:55] Um, I got his new brass knuckles. I bought [01:07:00] them. See, I have, I have a carry of permit so I can carry them. It's it. Knuckle

[01:07:04] Will Brink: [01:07:04] dusters. Remember, that's what we

[01:07:05] Carl Lanore: [01:07:05] call them in Brooklyn. I had a pair that I bought in easy rider magazine, but then Mike, my son, when he was about 12 or 13 years old, he took them out to show a friend and somebody clipped them.

[01:07:14] But I don't know if you can see what the back of the knuckles say, uh, you can't they say fuck around and find out. All right, but these are, these are Gallagher, original breasts, knuckles, and he'll be on, uh,

[01:07:28] Will Brink: [01:07:28] this month. Better be careful of that. Cancel culture. Carl talking that honesty

[01:07:32] Carl Lanore: [01:07:32] these days, listen, I'm not a popular guy to begin with, so they can't take much away from me.

[01:07:37] If I lose to who am I going to lose? I'm not Mark Bell. I'm not, you know, Dave Asprey. I don't have that audience. So I don't have to worry about it. All right. Look, we'll see everybody tomorrow with most super human radio. Thank you for being here. Take care. We'll talk to you later. [01:08:00] .