Guests: Dr. Hans Van Dongan, Ph.D. - Dr. Jason McDermott, PH.D. - Dr. Shobahn Gaddameedhi, Ph.D.
We have long discussed that night-shift workers and the higher rates of cancer. New research may now explain why cancer rates are much higher in night-shift workers than the general population. Identifying the pathway may allow night-shift workers to take special precautions. BTW if you like staying up all night and not necessarily a night-shift worker... pay attention.
PLUS
Part 2
Does Light Therapy Really Work
Guest: Patrick Johnson
Light therapy units are all the rage today. The Light Therapy Market size is valued at over USD 1 billion in 2020 and is expected to witness 5.1% category growth from 2021 to 2027. But do they really work? Are they deserving of you dollars?
Celluma Light Therapy: shrnetwork.biz/celluma Use code: SHR10 for 10% OFF.
Play
Sponsorship Inquiries: email This email address is being protected from spambots. You need JavaScript enabled to view it.
Show Notes:
Why Working The Night-Shit Leads To Cancer + Does Light Therapy Really Work
[5:08] Inspiration for the study on the correlation between shift work and cancer.
- The increased risk was an enigma.
- Wanted an MOA.
[7:00] Study design.
- 2 regiment: day shift for 3 days and 2 days of a simulated night shift.
- Iso caloric snacks, reclining chairs, and constant light exposure.
- Gene expression was examined.
[10:45] Does rotating shifts affect outcomes.
- Genetic expression in the tissues adapt much more quickly than biorhythms in the brain.
[14:50] What role does eating play?
[16:05] Time restricted eating.
- Minimizing food intake at night is still important.
[19:45] Insulin resistance as a precursor to top killing diseases in America.
[24:55] Was artificial light exposure taken into account?
- No, but it is worth looking at.
[30:22] Are there any steps to mitigate this damage?
[36:00] the importance of health checks when shift working.
- Circadian rhythms play a role in cancer.
[39:37] Can you become adjusted and age better by keeping your CR intact?
[46:20] Are cortisol levels the main culprit of metabolic disorder from shift work?
[50:50] Should large companies provide compensation for shift workers?
[1:01:38] The growth of light therapy technology.
[1:03:35] A LT device can be too powerful.
- There is a goldilocks range for the appropriate dose. Too high of a dose can cause oxidative damage.
[1:08:10] What are some of the misconceptions about light therapy?
[1:11:00] Uses for acne.
[1:14:18] Celluma for fine lines and wrinkles.
[1:18:15] Celluma is a device that is flexible and designed to be used in a clinical setting.
