The Pep Talk: Immunity, Autoimmunity, peptides and Fasting
with Co-host: Dr. Heather Smith-Fernandez, MD
The immune system has been front and center since this pandemic. The people who are at greatest risk are those with pre-existing conditions including autoimmune conditions. Fasting, or time restricted feeding, has been used to treat autoimmune conditions. A newcomer to physicians' treatment offerings is peptides. These sophisticated strings of amino acids act as cellular messengers that help cells "fix" problems. Is there a way to leverage these two powerful tools to increase the likelihood of positive outcome in a variety of disease states? Listen and learn.
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Show Notes:
The Pep Talk: Immunity, Autoimmunity, peptides and Fasting
[4:14] The FDA’s intrusion into the peptide industry has limited physicians’ ability to treat their patients.
[7:15] CJC-1295 vs without DAC.
[10:30] Peptide coalition efforts were made.
- FDA removed the use of peptides that had never shown harm and were GRAS.
[12:00] Protection of intellectual property.
- Patents are now being made on naturally occurring molecules of the human body.
[16:06] Auto immunity
- Several of the diseases of modernity probably have some sort of auto immune component.
- There are several autoimmune issues that don’t even have a name yet.
[20:45] How do peptides and fasting work together to treat autoimmunity?
- GH secretagogue and BPC-157 90 minutes after your last meal and in the morning before eating.
- Thymosin alpha 1 can be taken fasted or not.
[25:28] Ghrelin agonists to boost appetite in the elderly.
[37:50] Using GH at the site of injury.
[38:36] Intra articular GH for cartilage growth.
[40:25] peptides to use during fed states.
- BPC-157
- PT-141
- Alkaseltzer Gold can help with the nausea.
[43:30] Pituitary bleed from CJC-1295.
- Carl does not advocate long-acting CJC because it doesn’t mimic bio rhythmicity of GH release.
[48:35] Options for a 50 year old male.
- Thymosin alpha 1
- TB-4
- Pentosan polysulfate- 1 course/ year.
- Epitalon
- Hormone optimization- especially testosterone.
[55:45] Can mold and infection be tested in bloodwork?
- It would be very difficult.
[1:04:20] Elevated hemoglobin is not necessarily a clotting risk.

