Dr. Brad Schoenfeld, PhD
Few people have studied how to build muscle more efficiently than Dr. Schoenfeld. Carl respectfully refers to him as Doctor Hypertrophy. From his original mission of helping people Look Good Naked to the science and real-world applications of building muscle faster that have been adopted by the words best strength and physique athletes, he knows how to give you the physique you’ve dreamed of having. In his latest book “Science and Development of Muscle Hypertrophy“ he puts a finer point on the process than ever before. Come join the fun and be part of the live show on Facebook (https://shrnetwork.biz/FBLIVE
Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
https://pubmed.ncbi.nlm.nih.go
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Show Notes:
[4:21] The science and Development of Muscle Hypertrophy.
- 2nd edition textbook.
[6:20] How to assess muscle building progress over time.
[9:00] The book lays out several variables that can be altered to build and maintain muscle mass.
[17:13] Lifting as you age.
- Osteoarthritic issues are more common. This could suggest possible benefit to backing off from 1-5 rep maxes.
[20:10] What about advanced techniques?
- It all depends on the context in which you incorporate them.
- Heavy negative and loaded stretches have potential for higher muscle damage.
[24:10] What about aerobic exercise’s effect on muscle building?
- It can be very beneficial if properly managed.
[30:37] Nutrition.
- Most “hardgainers” are just not eating enough.
[31:30] ampK activators.
[36:00] myostatin.
- It is a myokine that acts as a governor on muscle growth.
- Its role in training remains questionable.
[40:30] NSAIDS.
- Chronic use in young people blunts hypertrophy.
- In individuals 60 and older, it starts to have a neutral to positive effect.
[48:40] Where to use BFR in your program.
- Use in tandem with heavier movements.
- Better for single joint movements.
[51:32] IGF-1 ec (mechano-growth factor).
[53:00] Any new thoughts about test levels and muscle?
- You can still build muscle at hypo gonadal levels. The effects will be blunted though.
[1:04:33] Study finding 5x faster muscle loss vs. gain when you individuals were immobile.

