Ryan Smith

Several peptides show efficacy in suppressing viruses like influenza. But COVID-19 is a reverse transcripted virus like HIV and EBOLA. Can these peptides also protect against COVID-19 and even be used to treat patients who have already contracted the virus? PLUS There are people who are regularly infected with viruses and never develop symptoms. Why is that? What's different about their immune system? Could the linkage between seasonality of influenza and virus spread be a result of the sun and vitamin D3? And if it is, what can you do in the winter?

Studies Cited About Sun Exposure > Oral D3 Supplementation > LL37 > Reverse Transcripted Virus Replication

Seasonal dynamics of influenza in Brazil: the latitude effect
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307116/

Antiviral Activity of the Human Cathelicidin, LL-37, and Derived peptides on Seasonal and Pandemic Influenza A Viruses
https://www.ncbi.nlm.nih.gov/pubmed/25909853

Effect of Cholecalciferol Supplementation on Vitamin D Status and Cathelicidin Levels in Sepsis: A Randomized, Placebo-Controlled Trial
https://www.ncbi.nlm.nih.gov/pubmed/26086941

The antimicrobial peptide LL-37 inhibits HIV-1 replication
https://www.ncbi.nlm.nih.gov/m/pubmed/17627504/

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SHR # 2479 :: The Pep Talk: Peptide Protocols To Protect Against and Treat COVID-19

Show Notes:

[ 4:00] Thymosin Alpha 1.

• Increases the body’s ability to find and kill viruses.
• It should help even if you are already infected with a virus.
• It has less side effects than placebo.
• It increases natural killer cells.
• 5mg 2x/week via subcutaneous injection.

[8:25] Reverse transcription viruses.

[10:30] LL-37

• Stopped replication of HIV in a study.
• 100-150mcg 2x/day.

[12:55] sensitivity to Thymosin Alpha 1?

• Try single use vial sans the benzyl alcohol.

[14:00] Rapid die off reaction.

• Gives flu like symptoms, nausea, and paresthesia.

[16:42] Selank.

• It is a cognitive peptide.
• Has anti-viral capabilities.
• Use it as a prophylactic and a treatment.
• 2mg nasally. Daily.

[21:11] Pentosan polysulfate.

• A small molecule drug.
• Used for osteoarthritis.
• Reduces viral entry into cells by enveloping the spikes on viruses.
• Injectable 2mg/kg 2x/week.

[24:03] Thymosin Beta 4.

• Repair and recovery.
• Extremely pleotropic.
• Upregulates IL-18

[35:53] Why don’t we hear more talk about these peptides from big pharma?

[49:06] How can physicians become educated?/ Is there anything exciting coming down the pike with peptides?

• SS31- mitochondrial peptide.

[58:11] Sunshine exposure as a virus preventative measure.

Show Transcript SHR # 2479 :: The Pep Talk: Peptide Protocols To Protect Against and Treat COVID-19