Dr. Daryl Davies, PhD & Joshua Silva
During this pandemic shut-down liquor stores have been deemed essential and remain open. What’s not essential are hangovers! A well-known hangover drug not only helps soothe pounding headaches but also triggers profound changes that protect the liver, USC scientists report in new findings that could help prevent alcohol-related harm. Alcohol use disorders constitute the most common form of substance abuse. About 88,000 people die of alcohol-related deaths annually -- the third leading preventable cause of death in the United States, according to the U.S. Centers for Disease Control and Prevention. PLUS The CDC owns some 28 vaccine patents. Why? And does it make our government any money? Simple questions I think need to be answered.
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-------------Studies Discussed In The Episode---------------------
Hangover drug shows wider benefits https://onlinelibrary.wiley.com/doi/full/10.1111/acer.14326
Show Notes:
[4:26] The toll of alcohol in the U.S.
- 80,000 deaths/year.
- 249 million dollars per year.
[8:40] cultural acceptance of alcohol.
[9:16] what preceded/ inspired this research?
- Intrigue from traditional Chinese medicine.
- Wanted to know why TCM works.
[15:53] Alcohol production from sugar, yeast, and mold in the gut. What about NAFLD?
- DHM benefits glucose metabolism in the liver.
[25:05] Why call DHM a drug in the literature?
[33:00] How does this molecule work?
- It increases key pools of NAD and increases alcohol clearance.
[36:23] Alcohol dehydrogenase.
- DHM does not just increase ADH.
- It also increases acetaldehyde clearance.
[42:11] Cytokines were also lowered in rats that were administered DHM.
[43:55] Dose response?
[54:48] Dies the quality of alcohol make a difference in the hang over?
- Yes, especially in darker liquors.
- Sugary drinks could be a double-whammy.
[57:45] The Asian flush.
- It stems from a deficiency in ALDH-2.
[1:00:16] Could DHM be stacked with activated charcoal?
[1:01:51] BPC-157?
[1:12:08] Rant: We are critical thinkers.
- Why does the CDC hold patents on Covid?
