SHR Exclusive, Fadogia and Testosterone

[00:00:09]   In 2006 Carl had the opportunity to interview Dr Toyin Yakubu, who at the time was a PhD student at the University of Ilorin Nigeria. He had a scientific paper published in the Asian Journal of Andrology detailing his studies on an extract used in Nigeria as a natural treatment for erectile dysfunction. What he discovered is that the extract elevates natural testosterone levels in a dose-dependent manner up to 600%. This interview led to the launch of several testosterone boosters which did not exist previously.

[00:01:40]   Toyin talks about his area of study and then elaborates on his scientific study that was published in the Asian Journal of Andrology.

[00:02:38]   Toyin explains:

• Fadogia agrestis has been used in Nigeria as a natural treatment for erectile dysfunction for many years.
• it is a shrub that grows about 1 to 3 feet tall.
• it is found in the northern parts of the country.
• the preparation he had to use to extract the active ingredients,
  • was to get the plant dried at 40 degrees Celsius,
  • grind it up into powder form,
  • extract the active principal,
  • and then made the required dosages he needed.
• Only the stem of the plant is used.
• It was found that the active ingredient was a saponin.

[00:04:45]   Listen to a detailed conversation on the various results of the study – remarkable!

[00:08:43]   What did you determine actually caused the rise in serum testosterone levels in in the rats? Toyin responds.

[00:09:36]   Toyin describes the mechanism of action of the Fadogia agrestis that increased testosterone levels?

[00:10:52]   Is it possible that there would be a point of administration that would become unhealthy because of the increase cholesterol levels to an unhealthy level? An interesting answer follows.

[00:12:08]   Tests were also conducted on any possible toxicity on the Fadogia agrestis – Toyin describes the results.

[00:13:17]   After the test subjects’ 10 day recovery period were completed, the testosterone levels did not fall back to as low as it was before the administration – Toyin explains why.

[00:14:18]   Toyin talks about his planned future studies on Fadogia agrestis and there is some discussion on funding for these studies.