Dr. George Touliatos, MD

A recent paper brought back the discussion about the role of anabolic steroids and changes in behavior. A link to psychosis in some individuals. And in women the potential appears to occur as well. This plus more is discussed.

Show Notes:

[6:17] Double standard of TRT in professional athletes.

• Everything has advanced in sports.
• Performance enhancements using surgery, training, etc are all allowed, but HRT is not.

[9:30] Does testosterone change mentality?

• Maybe, but only with super-physoiological doses.
• Sex hormones affect the brain.
• 10% of abusers showed psychosis in a small study.
• Abuse could increase pre dispositions.
• Abuse of the more exotic compounds (masteron/tren) can cause even greater effects.
• This could be due to the androgenicity of these compounds.
• 19-nor derivatives suppress the HPTA more severely and could be the reason for the effects reported from nandrolone.

[22:53] The medical orthodoxy needs to distinguish between AAS more thoroughly.

[56:04] Is pyschosis from PED’s dependent on individual pre-disposition?

• Some people will have their mental and peronality states affected from PED’s

[1:03:53] Metformin.

• Inhibits MToR and should not be taken around training or GH.
• GH can lead to insulin resistance.
• The is very little research of metofrmin in healthy individuals.
• Would metformin still suppress MToR from consumption of 400g of protein/day?
• Carl takes Rhapamycin 1 time per month and protein fasts for the next 3 days.
• Why not just do intermittent fasting instead of metformin?