SHR #2881: The Role of Time Restricted Eating Relevant to Cancer

: Natalie Kopitzke; 13 June 2022; 11 December 2022

The Role of Time Restricted Eating Relevant to Cancer
with Guest Dr. Amy Kirkham, Ph.D.

Older breast cancer survivors with cardiometabolic risk factors who restricted food intake to eight hours during the weekday, followed by 16 hours of fasting, lowered their risk of cardiovascular disease (CVD) after a few weeks, according to a new research letter publishing today in JACC: CardioOncology. The study is a part of the upcoming mini-focus issue, “Physical Activity and Lifestyle Interventions in Cancer.” The authors looked at 22 individuals with a body mass index who were classified as overweight or obese (>25kg/m2), had completed cardiotoxic treatment (anthracyclines, a commonly used chemotherapy drug) within the past one to six years, and were an average age of 66 years. For eight weeks participants were allowed to eat freely between 12-8 p.m. on weekdays and at any time on the weekends. Outside of those hours, participants were asked to consume only water, black coffee or black tea. Using the Canadian Cardiovascular Society scoring system to calculate the 10-year Framingham Risk Score, the authors found that CVD risk decreased from 10.9% to 8.6% at the end of the trial period.

Play

Show Notes:

The Role of Time Restricted Eating Relevant to Cancer

[00:07:29] Dr Amy speaks on how as a scientist; she becomes frustrated and concerned with some of the overreaching and hyperbole that media outlets use and how some of them distort the outcomes of research.

[00:08:21] The discussion continues on about the misconception people have about fasting.

[00:13:19] Carl shares his view on the magnitudinal affect that metabolic derangement has on health.

[00:15:47] Dr Amy explains why the study needed to be done and what proceeded this work and talks about some of the chemo therapies that damages the heart.

[00:19:55] Dr Amy gives a detailed description of the study.

[00:23:28] Dr Amy replies to Carl’s question of the possibility of chemotherapy affecting insulin sensitivity and expounds on how caloric restriction actually helps to increases resistance in healthy cells to the damaging effects of the cancer treatment.

[00:30:58] Dr Amy describes the cohort and their parameters and what the diet entailed.

[00:35:35] Dr Amy talks about a future study she has planned.

[00:36:05] The discussion continues on into the subject of diets used in studies where participants keep following the diet long after the study has completed.

[00:45:30] Follow the description on the markers that were looked at in the study.

[00:48:00] Carl talks about a riveting study done by Drs Kekwick and Pawan in the 1950’s.

[00:52:25] Dr Amy then describes a study and the findings thereof, where a 25% caloric deficit and time restricted eating were combined.

[00:55:42] Dr Amy replies to question of Carl’s whether the participants in her study participated in any kind of exercise.

[01:02:49] Carl asks Dr Amy to elaborate on any surprises she found in the study after which the discussion flows into dietary interventions within the group who incorporated it into their family lives.

[01:10:15] Carl stresses how important it is to get the information out to the public on how beneficial time restricted eating could be for overall health and wellness. Dr Amy joins in.

[01:14:00] Carl shares a few interesting facts about autophagy, non-dippers and to stop eating at least 3 hours before going to bed. Dr Amy joins in with some facts and views of her own.

----------

Carl Recommends >

Stay in touch with us! Get show highlights, tips, new research & offers in your inbox.