with Guest: Jean-Francois Tremblay
There's lots of misinformation floating around about peptides. Some have been repeated so many times by so many people, they haver become "true". We get to the bottom of some of the most common questions about peptide stability, storage, choice of diluent, injection site and much more on todays show.
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Show Notes:
The Pep Talk: Unraveling the Truth About peptides
[5:00] Common misconceptions about peptides
[9:00] Other factors that people should consider.
[11:00] Fragility of peptides
- Most peptide are not as fragile as people believe.
- Insulin and GH are two compounds that are somewhat fragile.
[22:40] Concentrations and solvents.
[25:23] Peptide storage
- They will hold in the freezer for a few years if not put into solution.
[33:30] It is surprising how long peptides will stay good.
- Degradation of peptides occurs on a spectrum and gradually over time. It is not like flipping a switch.
[36:50] Purity of the peptide is important.
- Even if it is 98% pure, if that remaining 2 % contains bacteria, it can be very harmful.
[42:50] Does benzyl alcohol/ filtering improve shelf stability or purity?
[46:00] What is the purpose behind using NaCl?
[49:30] Phosphate buffered peptides?
[50:20] Lyophilization
- Basically, it is a freeze drying of the peptide powder.
- The water is sublimed out of the peptide mixture using a vacuum.
- It is done for accuracy purposes as well as purity control purposes.
[59:40] The purpose of using mannitol and fillers to create the “puck” is for aesthetic purposes.
[1:04:20] ARA 290 for a type 1 diatbetic?
- The peptide itself has been less than what it was hyped up to be.
- Be careful with GH secretagogues as well.
[1:07:08] Does the vacuum seal mean anything?
[1:12:20] Injectable amino acids.
[1:14:00] Don’t get your peptide advice from someone just because they are self-proclaimed “experts”.
