The Pep Talk - GHK-Cu In Anti-aging and Regenerative Medicine
with guest Dr. Carl Paige, MD
This tiny protein found naturally in humans and mammals is attached to copper. Early research showed it has the ability to reduce the effects of aging in a variety of tissue. Its effects are pronounced in skin where it acts to promote the production of supporting structures (extracellular matrix) in the skin, increase collagen synthesis, regulate copper levels, and activate reparative cells. Its small molecular weight makes it ideal for cosmetics. One French study showed it may regrow hair! It's currently being investigated as an anti-inflammatory to replace corticosteroids, for use in nerve regeneration, as a stem cell growth factor, as a DNA protectant, and as a general anti-cancer agent.
From an original interview in May 2019 (SHR# 2345)
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Show Notes:
The Pep Talk - GHK-Cu in Anti-aging and Regenerative Medicine
[00:01:45] GHK-Cu is a naturally occurring tripeptide found in multiple tissues in the body.
- It functions locally as a copper buffer.
- It has physiological response reactions to inflammation and neuro-generation.
- It is a gene expression modulator
- It is good for the skin.
- It attaches to copper ions, which is especially important for various metabolic processes in the body.
[00:02:31] What does this mean for people with copper deficiencies?
- This peptide buffers and regulates copper in proper ranges in the body.
[00:04:03] GHK-Cu diminishes with age and iron overload creates copper metabolism abnormalities.
[00:04:29] GHK-Cu plays a profound role in protecting and regenerating liver cells.
- It causes new blood vessel growth and recovery on a cellular level.
- It has a positive effect on most tissues in the body .i.e., skin, neuro, and nerve regenerative properties.
- It stimulates collagen and restructures fibroblast in skin.
- Can tighten loose skin, reverse aging, and reduce wrinkles and age spots.
- It can be applied transdermally.
- There are possibilities of copper overload, but highly unlikely.
[00:06:02] Some studies proved the peptide to have a protective mechanism on DNA.
[00:06:30] The smaller peptides have pleotropic effects, in contrast to the bigger peptides like Human Growth hormone that have more narrow focused effects.
[00:07:54] Age reversal not only in skin, but also in nerve regeneration
[00:08:59] GHK-Cu should be able to cross the blood brain barrier, especially since it is naturally occurring.
[00:09:24] Dosing for various neuropathies.
- Systemically 1-2 mg per day.
- Frequency depends on volume of what it concentrates down to.
- For targeted treatment, inject it as close to the site in question as possible.
[00:15:30] Some studies show that GHK-Cu could have an effect on hair regrowth.
- In addition, it could restore hair color.
- Blocks DHT (Dihydrotestosterone)
- Acts as an anti-inflammatory.
- Aids in stem cell migration.
[00:16:00] Carl shares a few interesting facts about the adverse side effects of corticosteroids. Studies show that GHK-Cu could possibly replace corticosteroids. It could also be used together with other peptides to assist in recovery after corticosteroid treatment.
[00:18:55] How pronounced are the anti-inflammatory effects?
- We are not sure exactly how fast GHK-Cu would act.
[00:21:00] Corticosteroid injections increase the risk of injury i.e., tendon weakening and injuries.
[00:22:25] Prophylactic potential of GHK-Cu.
- From a skin regeneration and protection standpoint it has immense value prophylactically.
[00:24:15] An interesting discussion on hair growth regeneration ensues, do not miss out!
[00:26:59] peptides by en large, when taken in logical doses, are considered safe.
[00:28:07] Listen to Dr Carl’s advice to Carl on how to stack and use his prophylactic peptide regimen.
[00:33:54] Cancer treatment.
- GHK-Cu resets apoptotic mechanisms in skin cells.
- It upregulates genes that would help the body recover from cancer.
- Inhibits neuroblastoma cells when combined with vitamin C.
[00:35:54] Dosing to improve skin and hair quality.
- Apply topically to specific areas.
- There are local effects in the tissues GHK-Cu is applied to.
[00:37:25] Should you use Zinc supplementation while pulsing GHK-Cu peptides?
- If testing shows high copper levels, zinc will bring that levels down naturally.
- The balance of copper and zinc levels are extremely important in many metabolic functions in the body.
[00:39:23] peptides are magic! They resolve problems in the body as opposed to hide or dampen symptoms.
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