From a nutritional perspective, it is widely recognized that consuming a satiating diet can help prevent an overconsumption of calories through controlling appetite without deprivation. Interestingly, previous research has suggested that women are more sensitive to overfeeding and high-protein diets than men, which raises questions about sex-differences in appetite responses. To answer these questions, Bédard et al recruited 70 middle-aged, overweight-obese men and women to undergo a 4-week fully controlled feeding intervention using a traditional Mediterranean diet (MedDiet). An example of the daily nutritional composition of a 2500 kcal diet is presented in the image to the right, but everything was scaled to accommodate differences in energy intake among individuals so as to maintain weight. Before the intervention began, each participant was counselled on following the recommendations of the Canada’s Food Guide during a 4-week run-in period that led to similar dietary habits between men and women in the month prior...

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