Thymosin Beta 4 Reviewed with Dr. Carl Paige, MD
Thymosin Beta 4 also known as TB-500 made its debut in the thoroughbred race horse industry. Quickly adopted by athletes, many misconceptions about what it does or doesn't do in humans have followed. Dr. Paige gets to the truth.
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Download Episode SHR # 2338 :: The Pep Talk: Thymosin Beta 4 Reviewed
Show Notes:
[5:36] The improved recovery from TB-500 leads to anabolism, but it is not directly anabolic.
[6:29] The difference between Thymosin Beta-4 and TB-500.
- From a practical standpoint, they are very similar.
- Used for wound healing, anti-inflammation, angiogenesis, upregulation of VEG-F, modulation of cytokines to be anti-inflammatory, and erythriopoitic purposes.
- Discovered by the horse racing industry as a blood builder.
- These peptides should be cycled off.
[11:38] A pair of studies showed
- Post-ischemic event- TB-4 mitigated heart damage.
- TB-4 did the same with post cardiac events.
- These studies have not been repeated, however.
- Carl holds 2 vials of TB-4 in his freezer just in case of heart attack or stroke.
[14:55] TB-4 seems to mediate the direction of growth factors to heal injuries.
[16:08-16:27] “It’s almost as if TB-4 has the blueprint…..”
- It starts to be diluted in the body by the mid-30’s.
- Recovery from training can be thought of as a “coordinated” form of wound healing.
- TB-4 can be stacked with GH secretagogues for recovery.
[19:20] Correlations with cancer.
- There is a direct correlation with cancer cells, but it is felt that the TB-4 is upregulated to help eradicate the cancer cells instead of growing them.
[25:27] There exists research showing recovery of nervous tissue.
- Dosing: Therapeutic- 250mcg-300mcg daily cycled.
- Monitor blood count.
- Can be used in conjunction with BPC-157, collagen, and a GH secretagogue.
- Aggressive short term dose- 2mg every third day.
[29:12] Application to cross-trainers that are up in age.
- Be aware of WADA regulation.
- Stack it with BPC-157, collagen, and a GH secretagogue.
[31:14] Clinical reports for elbow injury.
- Not much research showing the efficacy of the compound stacks, but along with proper rest and nutrition, TB-4 should have much potential to help.
- Make sure to take enough collagen and 60-100mg of Vitamin C pre workout for soft tissue healing.
[35:20] Any legitimate pharmacies with good prices?
- Taylormade pharmaceuticals.
- You get what you pay for.
- The extra cost from pharmacies ensures that you know what you are taking.
- Once more doctors get on board with peptides, the prices will go down.
[43:14] Tailoring your expectation from peptides.
[44:12] Hair regrowth.
Medicaltranformationcenter.com
[49:50] Closing thoughts on TB-4.
peptidesociety.org
[50:25] Carl’s experiment with Epitalon.
- It is difficult to take extremely large doses subcutaneously.
- Intra-muscular and I.V. administrations are also options.
- Original study used 1 dosing instead of splitting doses.
- Use a half-hour before bed.
[55:28] peptides are in an early adoption phase.
-Lifestyle and nutrition should be managed to match the goal of the peptide administration.
[57:20] TB-500 with GH?
- Carl feels that it is short-sided to use simple GH with TB-500.
- A GH secretagogue would be more beneficial due to your pituitary releasing more than just 191 amino sequence GH.
[59:48] We do not know the point of diminishing returns with epitalon.
[1:00:30] How CJC 1295 can act as a GDA and clear enough glucose from the blood stream to make you light-headed.
Show Transcript SHR # 2338 :: The Pep Talk: Thymosin Beta 4 Reviewed
